| Gene | Short Name | Full Name |
|---|---|---|
| KWMTBOMO00631 (BGIBMGA003860) |
GATOR complex protein NPRL2
|
|
|
Description
An essential component of the GATOR subcomplex GATOR1 which functions as an inhibitor of the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:23723238, PubMed:27166823, PubMed:25512509). The two GATOR subcomplexes, GATOR1 and GATOR2, regulate the TORC1 pathway in order to mediate metabolic homeostasis, female gametogenesis and the response to amino acid limitation and complete starvation (PubMed:23723238, PubMed:27166823, PubMed:25512509). The function of GATOR1 in negatively regulating the TORC1 pathway is essential for maintaining baseline levels of TORC1 activity under nutrient rich conditions, and for promoting survival during amino acid or complete starvation by inhibiting TORC1-dependent cell growth and promoting catabolic metabolism and autophagy (PubMed:23723238, PubMed:27166823). In addition, this inhibition of TORC1 is necessary to maintain female fertility under normal conditions and during periods of nutrient stress (PubMed:24786828, PubMed:27672113, PubMed:25512509). GATOR1 and GATOR2 act at different stages of oogenesis to regulate TORC1 in order to control meiotic entry and promote oocyte growth and development (PubMed:25512509). After exactly four mitotic cyst divisions, the GATOR1 complex members (Iml1, Nprl2 and Nprl3) down-regulate TORC1 to slow cellular metabolism and promote the mitotic/meiotic transition (PubMed:25512509). At later stages of oogenesis, the mio and Nup44A components of the GATOR2 complex inhibit GATOR1 and thus activate TORC1 to promote meiotic progression, and drive oocyte growth and development (PubMed:25512509).
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00632 | ||
|
Annotation
|
||
|
Description
reverse_transcriptase_[Bombyx_mori]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00633 (BGIBMGA003861) | ||
|
Description
PREDICTED:_nitrogen_permease_regulator_2-like_protein_isoform_X1_[Bombyx_mori]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00634 |
Retrovirus-related Pol polyprotein from transposon TNT 1-94
|
|
|
Description
Retrovirus-related_Pol_polyprotein_from_transposon_TNT_1-94_[Papilio_machaon]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00635 | ||
|
Description
Retrovirus-related_Pol_polyprotein_from_transposon_TNT_1-94_[Papilio_machaon]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00636 (BGIBMGA003894) | ||
|
Description
PREDICTED:_proton-coupled_amino_acid_transporter_1-like_[Bombyx_mori]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00637 (BGIBMGA003892) |
Coatomer subunit beta'
|
|
|
Description
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00638 (BGIBMGA003892) |
Coatomer subunit beta'
+ More
Serine/threonine-protein phosphatase |
|
|
Description
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
+ More
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). |
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00639 (BGIBMGA003891) | ||
|
Description
PREDICTED:_transcription_initiation_factor_TFIID_subunit_4_[Bombyx_mori]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00640 (BGIBMGA003862) |
Chloride channel protein
|
|
|
Description
PREDICTED:_H(+)/Cl(-)_exchange_transporter_5_isoform_X2_[Bombyx_mori]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00641 | ||
|
Description
PREDICTED:_protein_furry_isoform_X2_[Bombyx_mori]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00642 (BGIBMGA003863) | ||
|
Annotation
|
||
|
Description
neuropeptide_receptor_A18_[Bombyx_mori]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00643 (BGIBMGA003890) | ||
|
Description
PREDICTED:_protein_furry_isoform_X3_[Bombyx_mori]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00644 (BGIBMGA003864) | ||
|
Annotation
|
||
|
Description
os_protein_[Bombyx_mori]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO00645 | ||
|
Annotation
|
||
|
Description
AF461149_1_transposase_[Bombyx_mori]
|
||
| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||