SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO00637  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA003892
Annotation
PREDICTED:_coatomer_protein_complex_subunit_beta_2_isoform_X1_[Bombyx_mori]
Full name
Coatomer subunit beta'      
Location in the cell
Nuclear   Reliability : 2.916
 

Sequence

CDS
ATGGAGGCCGTCGAGCCGAATTCAAAGATCACGAATACGGAACGAGACATCGCCGCGGAATACGCCGAAGCGAAACGACGAGGGCCCCTCAACATACCGCCGCTACTCAATCACAATCAAATACAAGATTCTGAAGGGGACAGCAGAGAGGATGCGACAAATGGGAACACGACGAGCGAAAGTCAACAGAAACGTAAAATTTCAATCGACATCATGGAGGAGATAGAACGGGAATTCGGTGAAATCGAATTCGAAAACCACGTCGATAACGATGACCTCTCGGACGTAGAAGACTTAATCGGCTAA
Protein
MEAVEPNSKITNTERDIAAEYAEAKRRGPLNIPPLLNHNQIQDSEGDSREDATNGNTTSESQQKRKISIDIMEEIEREFGEIEFENHVDNDDLSDVEDLIG

Summary

Description
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subunit
Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
Similarity
Belongs to the WD repeat COPB2 family.
Pfam
PF00400   WD40        + More
PF04053   Coatomer_WDAD
Interpro
IPR011044   Quino_amine_DH_bsu        + More
IPR017986   WD40_repeat_dom       
IPR036322   WD40_repeat_dom_sf       
IPR006692   Coatomer_WD-assoc_reg       
IPR001680   WD40_repeat       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR016453   COPB2       
IPR020472   G-protein_beta_WD-40_rep       
SUPFAM
SSF50978   SSF50978        + More
SSF50969   SSF50969       
Gene 3D
ProteinModelPortal

Ontologies

Topology

Subcellular location
Golgi apparatus membrane   The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.   With evidence from 2 publications.
Cytoplasmic vesicle   The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.   With evidence from 2 publications.
COPI-coated vesicle membrane   The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.   With evidence from 2 publications.
Length:
101
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0
Exp number, first 60 AAs:
0
Total prob of N-in:
0.21858
outside
1  -  101
 
 

Population Genetic Test Statistics

Pi
13.835587
Theta
21.358032
Tajima's D
-1.10439
CLR
0.000935
CSRT
0.117194140292985
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
28556443 VFNYNTLER 100.00 1e-10
26280517 ITIPSAASSINEEICNSFK 100.00 1e-04
27102218 QIAEEAGIAEGVASR 100.00 1e-04
Copyright@ 2018-2023    Any Comments and suggestions mail to:zhuzl@cqu.edu.cn   渝ICP备19006517号

渝公网安备 50010602502065号