Annotation

PREDICTED:_histone-lysine_N-methyltransferase_trithorax-like_[Bombyx_mori]

Description

Histone methyltransferase that methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (PubMed:12408863). Functions in segment determination through interaction with genes of bithorax (BX-C) and antennapedia (ANT-C) complexes (PubMed:2107543, PubMed:7958911). Acts as an activator of BX-C (PubMed:7924996). Involved in the very early regulation of homeotic genes expressed only in the posterior region of the embryo (PubMed:7924996, PubMed:25310983).      

Annotation

putative_cytoplasmic_dynein_light_chain_[Danaus_plexippus]

Description

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site. May also be a accessory component of axonemal dynein (By similarity).       + More
Plays a role in neuronal morphogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. Required for neurite outgrowth. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Unrelated to the role in retrograde microtubule-associated movement may play a role in the dimerization of cytoplasmic proteins/domains such as for ACVR2B. Binds to the cytoplasmic domain of ACVR2B and, in vitro, inhibits ACVR2B signaling (By similarity). Involved in the regulation of mitotic spindle orientation.      
Plays a role in neuronal morphogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation (By similarity). Unrelated to the role in retrograde microtubule-associated movement may play a role in the dimerization of cytoplasmic proteins/domains such as for ACVR2B. Binds to the cytoplasmic domain of ACVR2B and, in vitro, inhibits ACVR2B signaling (PubMed:27502274).      
(Microbial infection) Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site.      
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. May also be a accessory component of axonemal dynein (By similarity).      
Plays a role in neuronal morphogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation. Unrelated to the role in retrograde microtubule-associated movement may play a role in the dimerization of cytoplasmic proteins/domains such as for ACVR2B. Binds to the cytoplasmic domain of ACVR2B and, in vitro, inhibits ACVR2B signaling (By similarity).      

Annotation

ubiquitin-conjugating_enzyme_E2-17_kDa_[Papilio_polytes]

Description

Catalyzes the covalent attachment of ubiquitin to other proteins. Required for postreplication repair of UV-damaged DNA (PubMed:1902572). Involved in the negative regulation of the Ras/MAPK signaling pathway in the wing by acting with the putative E3 ligases poe, Kcmf1 and Ufd4 to mediate the ubiquitination and proteasomal degradation of rl/MAPK (PubMed:27552662).      

Annotation

PREDICTED:_RNA_exonuclease_1_homolog_[Bombyx_mori]

Description

O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.      

Annotation

Cappuccino-like_protein_[Operophtera_brumata]

Description

Cappuccino-like_protein_[Operophtera_brumata]

Annotation

PREDICTED:_deoxyuridine_5'-triphosphate_nucleotidohydrolase_[Papilio_polytes]

Description

PREDICTED:_deoxyuridine_5'-triphosphate_nucleotidohydrolase_[Papilio_polytes]

Annotation

PREDICTED:_coiled-coil_domain-containing_protein_174_[Bombyx_mori]

Description

PREDICTED:_coiled-coil_domain-containing_protein_174_[Bombyx_mori]

Annotation

PREDICTED:_uncharacterized_protein_LOC105842364_[Bombyx_mori]

Description

C-terminal region of a signal peptide.

Annotation

PREDICTED:_uncharacterized_protein_LOC105842361_[Bombyx_mori]

Description

C:proteasome complex

Annotation

PREDICTED:_uncharacterized_protein_LOC105388498_[Plutella_xylostella]

Description

F:aspartic-type endopeptidase activity

Annotation

peroxisomal_biogenesis_factor_3_[Bombyx_mori]

Description

peroxisomal_biogenesis_factor_3_[Bombyx_mori]

Annotation

PREDICTED:_glycoprotein_3-alpha-L-fucosyltransferase_A_[Bombyx_mori]

Description

Catalyzes alpha-1,3 glycosidic linkages of N-glycans (PubMed:11382750). Plays a role in neuronal development by promoting ventral nerve cord formation, possibly by promoting interactions between migrating cells and the extracellular matrix or by promoting neural activity (PubMed:21203496).      

Annotation

Uncharacterized_protein_OBRU01_03101_[Operophtera_brumata]

Description

Uncharacterized_protein_OBRU01_03101_[Operophtera_brumata]

Annotation

PREDICTED:_scaffold_attachment_factor_B1-like_isoform_X1_[Papilio_xuthus]

Description

PREDICTED:_scaffold_attachment_factor_B1-like_isoform_X1_[Papilio_xuthus]

Annotation

Chitin_synthase_regulatory_factor_2_[Operophtera_brumata]

Description

Chitin_synthase_regulatory_factor_2_[Operophtera_brumata]