| Gene | Short Name | Full Name |
|---|---|---|
| KWMTBOMO02732 (BGIBMGA003474) |
CK II subunit alpha CK II CK II alpha |
Casein kinase II subunit alpha
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Description
Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8. Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV. Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, SRF, MAX, JUN, FOS, MYC and MYB. Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function. Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1. Acts as an ectokinase that phosphorylates several extracellular proteins. Phosphorylates PML at 'Ser-565' and primes it for ubiquitin-mediated degradation. Plays an important role in the circadian clock function by phosphorylating ARNTL/BMAL1 at 'Ser-90' which is pivotal for its interaction with CLOCK and which controls CLOCK nuclear entry. Phosphorylates CCAR2 at 'Thr-454' (By similarity).
+ More
Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8. Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV. Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, SRF, MAX, JUN, FOS, MYC and MYB. Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function. Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1. Acts as an ectokinase that phosphorylates several extracellular proteins. Phosphorylates PML at 'Ser-565' and primes it for ubiquitin-mediated degradation (By similarity). Plays an important role in the circadian clock function by phosphorylating ARNTL/BMAL1 at 'Ser-90' which is pivotal for its interaction with CLOCK and which controls CLOCK nuclear entry. Phosphorylates CCAR2 at 'Thr-454' (By similarity). |
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02733 |
Cytoplasmic tRNA 2-thiolation protein 2
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Description
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02734 (BGIBMGA003475) | ||
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Description
PREDICTED:_elongation_factor_1_delta_isoform_X2_[Bombyx_mori]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02735 (BGIBMGA003476) | ||
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Description
PREDICTED:_protein_grainyhead_isoform_X5_[Bombyx_mori]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02736 (BGIBMGA003479) |
Protein grainyhead
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Description
Binds a CNS-specific regulatory element of the Dopa decarboxylase (Ddc) gene. Also interacts with sequences adjacent to other transcription units, including Ultrabithorax (Ubx) and engrailed (en). Activity in vivo may be required only at high levels transiently to activate the expression of Ddc in the CNS.
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02623 (BGIBMGA002660) | ||
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Annotation
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Description
Myrosinase_1_[Papilio_xuthus]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02624 | ||
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Description
P:DNA integration
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02625 (BGIBMGA002636) |
Sodium/hydrogen exchanger
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Description
sodium/hydrogen_exchanger_7?_9?_partial_[Manduca_sexta]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02626 (BGIBMGA002638) |
Sodium/hydrogen exchanger
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Description
PREDICTED:_sodium/hydrogen_exchanger_7_isoform_X4_[Amyelois_transitella]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02627 (BGIBMGA002659) | ||
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Description
PREDICTED:_metallo-beta-lactamase_domain-containing_protein_1_[Bombyx_mori]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02628 (BGIBMGA002639) | ||
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Description
PREDICTED:_aspartyl/asparaginyl_beta-hydroxylase_isoform_X1_[Bombyx_mori]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02629 (BGIBMGA002658) | ||
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Description
C:integral component of membrane
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02630 (BGIBMGA002640) |
Ubiquitin carboxyl-terminal hydrolase
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Description
Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin.
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02631 | ||
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Description
PREDICTED:_major_facilitator_superfamily_domain-containing_protein_12-like_isoform_X2_[Bombyx_mori]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02632 | ||
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Description
F:zinc ion binding
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||