Gene

KWMTBOMO02733

Annotation

PREDICTED:_cytoplasmic_tRNA_2-thiolation_protein_2_[Amyelois_transitella]

Location

Bomo_Chr5(-):9753222-9756280      View in EpiBrowser

Full name

Cytoplasmic tRNA 2-thiolation protein 2      

Location in the cell

Nuclear   Reliability : 3.18

CDS

ATGAAATGTAAAAAATGCAATTCATCTTCTGCATTAATTATCTTAAGAAAAAAAGATTTGTATTGCAGAGAGTGCTTCCTAGCAAATGTAACTCATAAATTCCGTTCTAGCATCGGAAAAAATAAAATATTAGGAAAGGCAGATAATGTTTTGATCTGTTTGTCGGGGAAGGAAGGCTCAACGGTTTTATTAGATTTGATTAATAATGCGTTATCCCTTGATAACCACAAGAAACTACGAATAACTCCAATTTTTCTACACTTGTGTGAAAACTACGAAACAATAAAGAATGTAATAGAACAATGTCAAAAGTACAATTATGACCTATATTCACCACATATATCAGAATATGTTCAATCCAAATCTCATATACCAATTGTGAATTCTTTACCTATTGTAAACAATGAACTTATAGAAGAGTACAATAACATGCAAAATAGCATGTTACCAACAGTTAAAGATGATTTCATAACTAATATTAAGAGAACTTTATATATTAGATATGCAAAGCTTTTGAATTGCAAATATATTTTCACTGGTGAAACAACAACCACTTTGGCCACAAAATTACTTGTAAATTTAGCTATTGGACGTGGCTCTCAAGTACAAAGTGATGTGGGATTTTTAGACAGTAGAGATATGGAAATCAAAATTATTAGACCTATGAAAGACATAAGTGAAGAGGAATTAAAACTTTATATCAACTCTAAGAATCTTAAAGTAAATGATAAACAAACATCCAAAGAGAATGAGCACACTAGCTTGCAAACAGTAATTAGTACTTTTGTAAGCAGTTTGCAAGAAAATTTTCCTTCCACAATTTCAACAATATGTAAAACTGCTGATAAAATTGGATTACAAGATGAATGTGACAATGAAAGGCATAATATGTGTGTTATTTGTCAAAGCATCTTGAAACCTGATGAGAAAGCAATCTCAGCTTTAGATGCAACAAGTATTTCCAAAATAGTTTCATTGAGAAAACATACAGACTCTGCTATAGATGTGGACATGGAGAAAAATGTTATTAACTCAACAATATTTCCTTATATTCATAATCGTCTATGTTATGCTTGCAGTAGAAATTATGCAGAAATTAAACAAAGCAAAATACCAAGTTACATTATCGAAACACAAAAATAA

Protein

MKCKKCNSSSALIILRKKDLYCRECFLANVTHKFRSSIGKNKILGKADNVLICLSGKEGSTVLLDLINNALSLDNHKKLRITPIFLHLCENYETIKNVIEQCQKYNYDLYSPHISEYVQSKSHIPIVNSLPIVNNELIEEYNNMQNSMLPTVKDDFITNIKRTLYIRYAKLLNCKYIFTGETTTTLATKLLVNLAIGRGSQVQSDVGFLDSRDMEIKIIRPMKDISEEELKLYINSKNLKVNDKQTSKENEHTSLQTVISTFVSSLQENFPSTISTICKTADKIGLQDECDNERHNMCVICQSILKPDEKAISALDATSISKIVSLRKHTDSAIDVDMEKNVINSTIFPYIHNRLCYACSRNYAEIKQSKIPSYIIETQK

Description

Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

Similarity

Belongs to the CTU2/NCS2 family.

Keywords

Complete proteome   Cytoplasm   Reference proteome   tRNA processing  

Feature

chain  Cytoplasmic tRNA 2-thiolation protein 2

Uniprot

A0A1E1WG68   A0A2A4JZ41   A0A2H1WWL8   A0A212FIZ1   A0A194RFZ8   A0A0C9RFS3   + More
U4U4P5   J3JV37   A0A1B6JV90   A0A2P8XGU2   A0A0L7KMA1   D6WYA9   A0A1Y1M3Q4   A0A1B6KH68   A0A067RN66   A0A1B6H2N7   A0A1Y1M405   A0A182H3B6   A0A2K7P687   Q17JB7   A0A293LYM3   A0A158NT32   A0A023GJQ7   V4CK50   T1I792   A0A0P4VUE8   R4FQD1   A0A195BG92   W5JGH8   A0A1S3JE92   A0A0T6AVL9   Q9VIV3   A0A2H8TP24   J9JW98   A0A182RFA1   A0A2R7WS26   A0A1A9V1K9   A0NEF7   A0A182LW56   A0A084W473   A0A1I8MEV7   A0A195C8I0   A0A0V0G776   B4I5W3   A0A0L8HE76   A0A195EFH6   A0A1L8DA21   A0A034VS20   A0A2S2P968   A0A0J9R5L9   B4Q9Z1   A0A182V9Y9   A0A182PHM8   A0A182FHY3   A0A2M4BN88   A0A195EZF8   A0A2M3Z9F5   A0A2R5LK50   A0A182NGW9   A0A182WIH7   A0A023F772   A0A0A1X3V7   A0A182QB04   D3TLU7   B0X911   A0A1W4VER7   A0A182XMW4   A0A3Q0IHQ7   A0A1B0FEC6   A0A1Q3F147   A0A1S3DUI6   A0A182HWS0   A0A1B0A943   A0A1B0C105   B4PAZ6   A0A182Y1A7   A0A2M3Z9D5   A0A151WJD9   B3NM45   A0A210R0K2   A0A026WSU3   T1KDJ5   E9IBE4   F4WG48   B3MN57   A0A2M3ZA98   A0A0K8TW66   B4JCV8   U5EXQ1   A0A0K2T6Y0   A0A1I8NMV7   A0A2G8JTY6   B4MYR2   B4M8J8   E9G223   B4KIW3   R7U248   W8BUL7  

Pubmed

22118469    26354079    23537049    22516182    29403074    26227816    + More
18362917    19820115    28004739    24845553    26483478    17510324    21347285    23254933    27129103    20920257    23761445    10731132    12537572    12537569    12364791    24438588    25315136    17994087    25348373    22936249    25474469    25830018    20353571    25244985    28812685    24508170    30249741    21282665    21719571    29023486    21292972    24495485   

EMBL

GDQN01005071    JAT85983.1    NWSH01000357    PCG77046.1    ODYU01011613    SOQ57465.1    + More
AGBW02008321    OWR53692.1    KQ460207    KPJ16738.1    GBYB01007215    JAG76982.1    KB632100    ERL88844.1    APGK01041758    BT127103    KB740997    AEE62065.1    ENN75847.1    GECU01004578    JAT03129.1    PYGN01002190    PSN31223.1    JTDY01009137    KOB64059.1    KQ971356    EFA09124.2    GEZM01041407    JAV80439.1    GEBQ01029212    JAT10765.1    KK852408    KDR24498.1    GECZ01000805    JAS68964.1    GEZM01041403    JAV80443.1    JXUM01024467    KQ560691    KXJ81259.1    CH477233    GFWV01009084    MAA33813.1    ADTU01025481    GBBM01001236    JAC34182.1    KB200170    ESP02605.1    ACPB03016783    GDKW01000287    JAI56308.1    GAHY01000464    JAA77046.1    KQ976488    KYM83612.1    ADMH02001577    ETN62015.1    LJIG01022687    KRT79248.1    AE014134    BT046166    AY118308    GFXV01004149    MBW15954.1    ABLF02039905    KK855397    PTY22368.1    AAAB01008960    AXCM01002623    ATLV01020284    KE525297    KFB45017.1    KQ978205    KYM96481.1    GECL01002270    JAP03854.1    CH480822    KQ418417    KOF87419.1    KQ978957    KYN26998.1    GFDF01010776    JAV03308.1    GAKP01014600    GAKP01014599    JAC44353.1    GGMR01013119    MBY25738.1    CM002910    KMY91024.1    CM000361    GGFJ01005323    MBW54464.1    KQ981897    KYN33685.1    GGFM01004381    MBW25132.1    GGLE01005765    MBY09891.1    GBBI01001622    JAC17090.1    GBXI01008857    JAD05435.1    AXCN02000361    EZ422399    ADD18675.1    DS232513    CCAG010022386    GFDL01013764    JAV21281.1    APCN01001535    JXJN01023850    CM000158    GGFM01004395    MBW25146.1    KQ983039    KYQ47920.1    CH954179    NEDP02000981    OWF54553.1    KK107109    QOIP01000008    EZA59053.1    RLU19939.1    CAEY01002017    GL762111    EFZ22034.1    GL888128    EGI66815.1    CH902620    GGFM01004702    MBW25453.1    GDHF01034014    GDHF01029495    JAI18300.1    JAI22819.1    CH916368    GANO01000837    JAB59034.1    HACA01004402    CDW21763.1    MRZV01001265    PIK39188.1    CH963913    CH940654    GL732530    EFX86173.1    CH933807    AMQN01009843    KB306344    ELT99947.1    GAMC01003658    JAC02898.1   

Proteomes

UP000218220    UP000007151    UP000053240    UP000030742    UP000019118    UP000245037    + More
UP000037510    UP000007266    UP000027135    UP000069940    UP000249989    UP000008820    UP000005205    UP000030746    UP000015103    UP000078540    UP000000673    UP000085678    UP000000803    UP000007819    UP000075900    UP000078200    UP000007062    UP000075883    UP000030765    UP000095301    UP000078542    UP000001292    UP000053454    UP000078492    UP000000304    UP000075903    UP000075885    UP000069272    UP000078541    UP000075884    UP000075920    UP000075886    UP000002320    UP000192221    UP000076407    UP000079169    UP000092444    UP000075840    UP000092445    UP000092460    UP000002282    UP000076408    UP000075809    UP000008711    UP000242188    UP000053097    UP000279307    UP000015104    UP000007755    UP000007801    UP000001070    UP000095300    UP000230750    UP000007798    UP000008792    UP000000305    UP000009192    UP000014760   

PRIDE

Q9VIV3    B0X911    B3MN57    B4JCV8    B4KIW3   

Pfam

PF10288   CTU2        + More
PF01171   ATP_bind_3
PF01425   Amidase
PF00271   Helicase_C
PF00270   DEAD
PF00698   Acyl_transf_1
PF07177   Neuralized

Interpro

IPR014729   Rossmann-like_a/b/a_fold        + More
IPR019407   CTU2       
IPR011063   TilS/TtcA_N       
IPR036928   AS_sf       
IPR023631   Amidase_dom       
IPR020556   Amidase_CS       
IPR027417   P-loop_NTPase       
IPR011545   DEAD/DEAH_box_helicase_dom       
IPR014014   RNA_helicase_DEAD_Q_motif       
IPR001650   Helicase_C       
IPR014001   Helicase_ATP-bd       
IPR000629   RNA-helicase_DEAD-box_CS       
IPR016035   Acyl_Trfase/lysoPLipase       
IPR020801   PKS_acyl_transferase       
IPR016036   Malonyl_transacylase_ACP-bd       
IPR014043   Acyl_transferase       
IPR001227   Ac_transferase_dom_sf       
IPR006573   NHR_dom       

SUPFAM

SSF75304   SSF75304        + More
SSF52540   SSF52540       
SSF52151   SSF52151       
SSF55048   SSF55048       

Gene 3D

3.40.50.620     3.90.1300.10     3.40.366.10    

CDD

cd00079  HELICc

ProteinModelPortal

A0A1E1WG68   A0A2A4JZ41   A0A2H1WWL8   A0A212FIZ1   A0A194RFZ8   A0A0C9RFS3   + More
U4U4P5   J3JV37   A0A1B6JV90   A0A2P8XGU2   A0A0L7KMA1   D6WYA9   A0A1Y1M3Q4   A0A1B6KH68   A0A067RN66   A0A1B6H2N7   A0A1Y1M405   A0A182H3B6   A0A2K7P687   Q17JB7   A0A293LYM3   A0A158NT32   A0A023GJQ7   V4CK50   T1I792   A0A0P4VUE8   R4FQD1   A0A195BG92   W5JGH8   A0A1S3JE92   A0A0T6AVL9   Q9VIV3   A0A2H8TP24   J9JW98   A0A182RFA1   A0A2R7WS26   A0A1A9V1K9   A0NEF7   A0A182LW56   A0A084W473   A0A1I8MEV7   A0A195C8I0   A0A0V0G776   B4I5W3   A0A0L8HE76   A0A195EFH6   A0A1L8DA21   A0A034VS20   A0A2S2P968   A0A0J9R5L9   B4Q9Z1   A0A182V9Y9   A0A182PHM8   A0A182FHY3   A0A2M4BN88   A0A195EZF8   A0A2M3Z9F5   A0A2R5LK50   A0A182NGW9   A0A182WIH7   A0A023F772   A0A0A1X3V7   A0A182QB04   D3TLU7   B0X911   A0A1W4VER7   A0A182XMW4   A0A3Q0IHQ7   A0A1B0FEC6   A0A1Q3F147   A0A1S3DUI6   A0A182HWS0   A0A1B0A943   A0A1B0C105   B4PAZ6   A0A182Y1A7   A0A2M3Z9D5   A0A151WJD9   B3NM45   A0A210R0K2   A0A026WSU3   T1KDJ5   E9IBE4   F4WG48   B3MN57   A0A2M3ZA98   A0A0K8TW66   B4JCV8   U5EXQ1   A0A0K2T6Y0   A0A1I8NMV7   A0A2G8JTY6   B4MYR2   B4M8J8   E9G223   B4KIW3   R7U248   W8BUL7  

KEGG

101747220    K14169 cytoplasmic tRNA 2-thiolation protein 2 | (RefSeq) cytoplasmic tRNA 2-thiolation protein 2

PATHWAY

04122    Sulfur relay system - Bombyx mori (domestic silkworm)

GO

GO:0002098   GO:0032447   GO:0016779   GO:0005737   GO:0034227   GO:0000049   GO:0016783   GO:0002143   GO:0005829   GO:0016787   GO:0005524   GO:0006468   GO:0005634   GO:0005667   GO:0006631   GO:0006635   GO:0006281   GO:0048384  

PANTHER

PTHR20882  

Subcellular location

Cytoplasm  

Length:

380

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.14457

Exp number, first 60 AAs:

0.00925

Total prob of N-in:

0.08420

outside

1  -  380

 

 

Pi

190.827782

Theta

208.940535

Tajima's D

-0.265987

CLR

31.858895

CSRT

0.299035048247588

Interpretation

Uncertain