Gene

KWMTBOMO02625

Pre Gene Modal

BGIBMGA002636

Annotation

sodium/hydrogen_exchanger_7?_9?_partial_[Manduca_sexta]

Location

Bomo_Chr5(+):7524528-7539474      View in EpiBrowser

Full name

Sodium/hydrogen exchanger      

Location in the cell

PlasmaMembrane   Reliability : 4.937

CDS

ATGTTGTTTACATTGAACTTCAATGCTAAACTAAGTACGGACATCGCACTAGATGCTAAAGCCACTCTTTTACACCGTATAGATAGTTTGAATCTACTTATTTACACTTGCCTCCTAACTCTTACTGTGCTAACGATCTGGGTGTTCAAACATCGTCGAGTCAGCTGGCTTCACGAAACTGGACTGGCAGTAATTTATGGTCTCATAGTAGGAGCAATCATTCGTTATGCAGGCAGTACGAATCATATTACCCACATCAATGTCAATCCAGAACCCGGCACAACCTACAACCTGTCTGTACCACCAGATATGTTGCGTTTTCACTTCCCTGCTAGCTTACCGATCACACCAGGAGATTCTCCAATAGCAAACAAAACATACGCATATAGCTTCAGGGGTGAAATAGTAAATGTAGAACAAAATGAAATTGATCTCAAAGCTACGTTTGATCCTGAGATATTCTTTAATATAATTTTACCGCCAATCATATTCCATGCGGGCTATTGCCTGAAACGGAAATATTTCTTCCGAAACTTGGGGGCGATATTGACATTCGCTATGGTCGGAACAGCTCTCTCGGCTTTAGTTATAGGAGCACTGATGTACGGCTGCGTGCAACTAATGCCGGCATCATTGGCATCCAGCTTCACGTTCCTTGACACCCTGTATTTCGGGGCATTGATCTCACCAACGGACCCTTTAACGGTGCTGGCTATATTCTCACAGTTGAAGGTGGACGTCAATTTGTATGCGATGATATTTGGTGAAAGCGTTCTGAATGACGCCGTCGCTCTTGTACTTAGCGGAGCGATACAAAACTACGAAACGAGATACTCGCATGACGGCGGCTTCGAAATATCCGGTTTCCTAGGAGCCATTGGGGATTTCATAGGAATATTCAGCCTTTCTCTGCTAGTTGGTGCTCTGATGGGATGTTTGACAGCATTGATATCCTTTTAA

Protein

MLFTLNFNAKLSTDIALDAKATLLHRIDSLNLLIYTCLLTLTVLTIWVFKHRRVSWLHETGLAVIYGLIVGAIIRYAGSTNHITHINVNPEPGTTYNLSVPPDMLRFHFPASLPITPGDSPIANKTYAYSFRGEIVNVEQNEIDLKATFDPEIFFNIILPPIIFHAGYCLKRKYFFRNLGAILTFAMVGTALSALVIGALMYGCVQLMPASLASSFTFLDTLYFGALISPTDPLTVLAIFSQLKVDVNLYAMIFGESVLNDAVALVLSGAIQNYETRYSHDGGFEISGFLGAIGDFIGIFSLSLLVGALMGCLTALISF

Similarity

Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

Feature

chain  Sodium/hydrogen exchanger

Uniprot

H9IZF1   D2KMI1   A0A2H1VWB1   A0A2Z4GWX1   A0A2A4JUY0   A0A2A4JVL3   + More
A0A2A4JTS3   A0A2A4JVC2   A0A2A4JUI8   A0A194Q288   A0A194R361   A0A0K8TXJ3   A0A1A9UYP2   A0A1A9XML2   A0A1B0BVM4   A0A1I8PE93   W8BTK4   A0A182TQK6   W8AUG9   A0A1I8PEA1   A0A1I8PE00   A0A1I8PE18   A0A1I8PE69   A0A1I8PEA0   A0A1Q3F7C0   A0A1Q3F6Z9   A0A0K8USU6   A0A0K8VGE2   A0A2M4AAN2   A0A0K8UXP3   A0A0K8W9I2   A0A2M4CG72   W5J3J7   A0A2M4AAL2   A0A0K8VXZ0   A0A2M4CG76   A0A1I8MVT3   A0A2M3Z299   A0A2M3Z296   A0A2M4BGE9   A0A182KWG4   A0A2M4BG26   A0A1A9WXG0   A0A034W3A9   A0A034VY73   A0A0A1X355   A0A1I8MVT2   A0A0A1WV94   T1PD84   A0A1I8MVU5   A0A034W0Q3   A0A1I8MVU3   A0A1I8MVT9   A0A034W1P4   A0A182R405   A0A0A1X9G6   A0A182X697   A0A182UU04   A0A034W2B4   A0A182K3T6   A0A182IBB7   A0A1Q3FA22   A0A182P6F1   A0A1Q3FD16   A0A034W2A9   A0A182VTG5   A0A182YLQ1   A0A182NAM3   A0A1Q3F903   A0A1S4GZS0   A0A1Q3F8B3   A0A1Q3F8W7   A0A336MX14   A0A336LGG0   A0A1Q3F8S1   Q7Q8A8   A0A336LCL2   A0A1B0FF58   A0A336LG79   A0A1Q3F953   A0A182MTC0   A0A1B6FZG6   A0A1Q3FBA5   A0A1Q3F9C2   A0A182J6Y2   B0W4X3   A0A1Q3F9J5   A0A084VMI0   A0A0K8TQS9   A0A1L8DUV9   A0A1L8DUX4   A0A1L8DUW1   A0A1L8DUY2   A0A1L8DUV5   A0A1L8DUX3   A0A1L8DVA7   A0A1L8DUX6   A0A067R0D5   Q17JD8   Q9U624  

Pubmed

19121390    20696265    29908900    26354079    24495485    20920257    + More
23761445    25315136    20966253    25348373    25830018    25244985    12364791    24438588    26369729    24845553    17510324    11719534   

EMBL

BABH01014149    BABH01014150    BABH01014151    BABH01014152    GU229277    ADA60969.1    + More
ODYU01004836    SOQ45127.1    MH048892    AWW06964.1    NWSH01000598    PCG75434.1    PCG75432.1    PCG75435.1    PCG75433.1    PCG75436.1    KQ459589    KPI97520.1    KQ460870    KPJ11680.1    GDHF01033539    JAI18775.1    JXJN01021373    JXJN01021374    GAMC01014101    JAB92454.1    GAMC01014100    JAB92455.1    GFDL01011642    JAV23403.1    GFDL01011709    JAV23336.1    GDHF01022570    JAI29744.1    GDHF01014699    JAI37615.1    GGFK01004471    MBW37792.1    GDHF01020880    JAI31434.1    GDHF01004784    JAI47530.1    GGFL01000169    MBW64347.1    ADMH02002110    ETN58922.1    GGFK01004503    MBW37824.1    GDHF01008546    JAI43768.1    GGFL01000168    MBW64346.1    GGFM01001901    MBW22652.1    GGFM01001906    MBW22657.1    GGFJ01002998    MBW52139.1    GGFJ01002864    MBW52005.1    GAKP01010714    JAC48238.1    GAKP01010716    JAC48236.1    GBXI01008735    JAD05557.1    GBXI01011525    JAD02767.1    KA645898    AFP60527.1    GAKP01010713    JAC48239.1    GAKP01010715    JAC48237.1    GBXI01006706    JAD07586.1    GAKP01010712    JAC48240.1    APCN01000664    GFDL01010683    JAV24362.1    GFDL01009571    JAV25474.1    GAKP01010717    JAC48235.1    GFDL01011046    JAV23999.1    AAAB01008944    GFDL01011230    JAV23815.1    GFDL01011053    JAV23992.1    UFQS01003548    UFQT01003548    SSX15752.1    SSX35104.1    SSX15753.1    SSX35105.1    GFDL01011132    JAV23913.1    EAA10143.4    UFQS01003374    UFQT01003374    SSX15576.1    SSX34939.1    CCAG010001470    SSX15575.1    SSX34938.1    GFDL01010941    JAV24104.1    AXCM01001606    GECZ01014197    JAS55572.1    GFDL01010180    JAV24865.1    GFDL01010899    JAV24146.1    DS231839    EDS34311.1    GFDL01010829    JAV24216.1    ATLV01014596    KE524975    KFB39174.1    GDAI01000889    JAI16714.1    GFDF01003856    JAV10228.1    GFDF01003858    JAV10226.1    GFDF01003857    JAV10227.1    GFDF01003855    JAV10229.1    GFDF01003860    JAV10224.1    GFDF01003852    JAV10232.1    GFDF01003859    JAV10225.1    GFDF01003853    JAV10231.1    KK852804    KDR16186.1    CH477233    EAT46765.1    AF199463    AAF13702.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000078200    UP000092443    + More
UP000092460    UP000095300    UP000075902    UP000000673    UP000095301    UP000075882    UP000091820    UP000075900    UP000076407    UP000075903    UP000075881    UP000075840    UP000075885    UP000075920    UP000076408    UP000075884    UP000007062    UP000092444    UP000075883    UP000075880    UP000002320    UP000030765    UP000027135    UP000008820   

PRIDE

H9IZF1    Q9U624   

Pfam

PF00999   Na_H_Exchanger

Interpro

IPR006153   Cation/H_exchanger        + More
IPR018422   Cation/H_exchanger_CPA1       
IPR002090   Na/H_exchanger_6       
IPR004709   NaH_exchanger       

ProteinModelPortal

H9IZF1   D2KMI1   A0A2H1VWB1   A0A2Z4GWX1   A0A2A4JUY0   A0A2A4JVL3   + More
A0A2A4JTS3   A0A2A4JVC2   A0A2A4JUI8   A0A194Q288   A0A194R361   A0A0K8TXJ3   A0A1A9UYP2   A0A1A9XML2   A0A1B0BVM4   A0A1I8PE93   W8BTK4   A0A182TQK6   W8AUG9   A0A1I8PEA1   A0A1I8PE00   A0A1I8PE18   A0A1I8PE69   A0A1I8PEA0   A0A1Q3F7C0   A0A1Q3F6Z9   A0A0K8USU6   A0A0K8VGE2   A0A2M4AAN2   A0A0K8UXP3   A0A0K8W9I2   A0A2M4CG72   W5J3J7   A0A2M4AAL2   A0A0K8VXZ0   A0A2M4CG76   A0A1I8MVT3   A0A2M3Z299   A0A2M3Z296   A0A2M4BGE9   A0A182KWG4   A0A2M4BG26   A0A1A9WXG0   A0A034W3A9   A0A034VY73   A0A0A1X355   A0A1I8MVT2   A0A0A1WV94   T1PD84   A0A1I8MVU5   A0A034W0Q3   A0A1I8MVU3   A0A1I8MVT9   A0A034W1P4   A0A182R405   A0A0A1X9G6   A0A182X697   A0A182UU04   A0A034W2B4   A0A182K3T6   A0A182IBB7   A0A1Q3FA22   A0A182P6F1   A0A1Q3FD16   A0A034W2A9   A0A182VTG5   A0A182YLQ1   A0A182NAM3   A0A1Q3F903   A0A1S4GZS0   A0A1Q3F8B3   A0A1Q3F8W7   A0A336MX14   A0A336LGG0   A0A1Q3F8S1   Q7Q8A8   A0A336LCL2   A0A1B0FF58   A0A336LG79   A0A1Q3F953   A0A182MTC0   A0A1B6FZG6   A0A1Q3FBA5   A0A1Q3F9C2   A0A182J6Y2   B0W4X3   A0A1Q3F9J5   A0A084VMI0   A0A0K8TQS9   A0A1L8DUV9   A0A1L8DUX4   A0A1L8DUW1   A0A1L8DUY2   A0A1L8DUV5   A0A1L8DUX3   A0A1L8DVA7   A0A1L8DUX6   A0A067R0D5   Q17JD8   Q9U624  

PDB

2MDF     E-value=2.25818e-07,     Score=130

KEGG

101746680    K12041 solute carrier family 9 (sodium/hydrogen exchanger), member 6/7 | (RefSeq) sodium/hydrogen ex

GO

GO:0016021   GO:0006885   GO:0015385   GO:0098719   GO:0015386   GO:0005886   GO:0055037   GO:0051453   GO:0071805   GO:0048471   GO:0006814   GO:0006812   GO:0015299   GO:0006631   GO:0006635   GO:0006281   GO:0048384   GO:0055085  

PANTHER

PTHR10110  

Length:

319

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

139.22941

Exp number, first 60 AAs:

24.10586

Total prob of N-in:

0.33182

POSSIBLE N-term signal

sequence

outside

1  -  26

TMhelix

27  -  49

inside

50  -  55

TMhelix

56  -  78

outside

79  -  152

TMhelix

153  -  170

inside

171  -  178

TMhelix

179  -  201

outside

202  -  220

TMhelix

221  -  243

inside

244  -  295

TMhelix

296  -  318

outside

319  -  319

 

 

Pi

244.390457

Theta

187.513233

Tajima's D

1.488347

CLR

0.192613

CSRT

0.779911004449777

Interpretation

Uncertain