Annotation

PREDICTED:_cysteine_protease_ATG4D_[Bombyx_mori]

Description

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.       + More
Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.      
Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability (By similarity).      

Annotation

PREDICTED:_protein_farnesyltransferase_subunit_beta_[Bombyx_mori]

Description

Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.      

Annotation

PREDICTED:_mediator_of_RNA_polymerase_II_transcription_subunit_6_isoform_X1_[Bombyx_mori]

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.       + More
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).      

Annotation

PREDICTED:_Down_syndrome_cell_adhesion_molecule-like_protein_Dscam2_[Bombyx_mori]

Description

PREDICTED:_Down_syndrome_cell_adhesion_molecule-like_protein_Dscam2_[Bombyx_mori]

Annotation

gag-like_protein_[Bombyx_mori]

Description

gag-like_protein_[Bombyx_mori]

Annotation

reverse_transcriptase_[Bombyx_mori]

Description

reverse_transcriptase_[Bombyx_mori]

Annotation

PREDICTED:_JNK1/MAPK8-associated_membrane_protein_[Amyelois_transitella]

Description

PREDICTED:_JNK1/MAPK8-associated_membrane_protein_[Amyelois_transitella]

Annotation

uridine_diphosphate_glucosyltransferase_precursor_[Bombyx_mori]

Description

Catalyzes the transfer of glucose from UDP-glucose to ecdysteroids which are insect molting hormones.      

Annotation

PREDICTED:_cyclin-dependent_kinase_20_[Papilio_xuthus]

Description

Involved in cell growth. Activates cdk2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity). Required for high-level Shh responses in the developing neural tube. Together with tbc1d32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing gli2 to be properly activated in response to SHH signaling.       + More
Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity). Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling.      
Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling. Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity).      

Annotation

Yokozuna_[Bombyx_mori]

Description

Yokozuna_[Bombyx_mori]

Annotation

PREDICTED:_transcriptional_adapter_2B_isoform_X1_[Bombyx_mori]

Description

Required for the function of some acidic activation domains, which activate transcription from a distant site. Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.      

Annotation

PREDICTED:_WD_repeat-containing_protein_37_[Amyelois_transitella]

Description

PREDICTED:_WD_repeat-containing_protein_37_[Amyelois_transitella]

Annotation

PREDICTED:_gastrula_zinc_finger_protein_XlCGF26.1-like_[Papilio_machaon]

Description

PREDICTED:_gastrula_zinc_finger_protein_XlCGF26.1-like_[Papilio_machaon]

Annotation

PREDICTED:_probable_ATP-dependent_RNA_helicase_spindle-E_[Bombyx_mori]

Description

Probable ATP-binding RNA helicase which plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity).       + More
Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons. Involved in the repression of LTR retrotransposon copia. Also involved in telomere regulation by repressing specialized telomeric retroelements HeT-A, TAHRE, and TART; Drosophila telomeres being maintained by transposition of specialized telomeric retroelements. Involved in telomeric trans-silencing, a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin has the capacity to repress in trans in the female germline, a homologous transposon, or transgene located in euchromatin. Involved in the repression of testis-expressed Stellate genes by the homologous Su(Ste) repeats. Required for anteroposterior and dorsoventral axis formation during oogenesis (By similarity).      

Annotation

PREDICTED:_C-1-tetrahydrofolate_synthase?_cytoplasmic_isoform_X2_[Bombyx_mori]

Description

PREDICTED:_C-1-tetrahydrofolate_synthase?_cytoplasmic_isoform_X2_[Bombyx_mori]