Gene
KWMTBOMO15146
Pre Gene Modal
BGIBMGA004927
Annotation
PREDICTED:_mediator_of_RNA_polymerase_II_transcription_subunit_6_isoform_X1_[Bombyx_mori]
Full name
Mediator of RNA polymerase II transcription subunit 6
Alternative Name
Mediator complex subunit 6
Location in the cell
Nuclear Reliability : 3.039
Sequence
CDS
ATGATGCCCGGCAGGATTGGAAATATATCACTGGCCAATGAGAATCCTTTGGGATTATCATGGCATGATTCAGCATGGATACCGTTATTGAATCCATCCAATATTATGGATTATTTTTCAGAAAGATCTAATCCATTTTTCGATCGGACATGTAATAATGAAATTGTTAAAATGCAACGTTTAAGTATGGACCAGTTGCAAAATATGACTGGATTGGAATACATTTTATTGCATGTTCAAGAGCCAATTCTCTATGTTGTGCGTAAACAACACAGGCATAGCCCAACACAAGCAACACCCCTTGCAGATTATTATGTGATTGCTGGTATTGTTTATCAGGCTCCTGATCTCGCAAGTGTTTTGAATTCTAGGCTGCTGTCAGCTGTTCATCATCTTCAGTGCTCTTTTGAAGAAACCATGTCATATTCAAGATATCACCCCAGTAAAGGATATTGGTGGGATTTTAAACCTACTAAGCCTGGGTTAGGATCTTACAATTCTAGTCAAACAGCACCGAAAGATGTTTCAAGTACTCCAAAGGAAGAACCTTCAACTCTATTCCAGCGGCAGAGAGTTGATATGCTATTAGCAGAACTTGTGAGGCAGTTTCCATTACCTGTTACTCAAACTGCACCAAATCAGGCAAATGGAGTGACAGTGAAGACTGAAGTCTCCAATGACAAAAATGAAAAAGGAATGGAAGGGAATCTTAACAATATAACTATTAAACAAGAGCCAGTGGATCCCACAACATCTGAAATGACAAATGGGTCAATGCAAGGTCAAATTGAAATAAAAACTGAAATTAAACAGGAAAACATGAAACCACCTCCTGAGAAAAAACCAAGGAATTTATAG
Protein
MMPGRIGNISLANENPLGLSWHDSAWIPLLNPSNIMDYFSERSNPFFDRTCNNEIVKMQRLSMDQLQNMTGLEYILLHVQEPILYVVRKQHRHSPTQATPLADYYVIAGIVYQAPDLASVLNSRLLSAVHHLQCSFEETMSYSRYHPSKGYWWDFKPTKPGLGSYNSSQTAPKDVSSTPKEEPSTLFQRQRVDMLLAELVRQFPLPVTQTAPNQANGVTVKTEVSNDKNEKGMEGNLNNITIKQEPVDPTTSEMTNGSMQGQIEIKTEIKQENMKPPPEKKPRNL
Summary
Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subunit
Component of the Mediator complex.
Similarity
Belongs to the Mediator complex subunit 6 family.
Keywords
Activator
Complete proteome
Nucleus
Reference proteome
Transcription
Transcription regulation
Feature
chain Mediator of RNA polymerase II transcription subunit 6
Uniprot
H9J5Y6
A0A2H1WZB3
A0A2A4JNP2
A0A1E1WH74
A0A194RL03
I4DNT0
+ More
A0A212ETR4 A0A3S2M2X9 S4NID5 A0A194PFV9 A0A2P8Z751 A0A2J7PR61 A0A0J7KX34 A0A1B6GDJ3 A0A1B6HIG5 A0A023EM62 D6WR32 A0A084VD12 E2AKZ6 A0A1B0DKT5 A0A182IYZ0 A0A232F3E6 K7IQE0 A0A1L8DHG0 A0A154PHA1 A0A195C6J9 A0A195EZZ0 E2BN56 A0A158NT22 A0A182Y657 A0A2A3EQV9 A0A088A0I1 A0A182NNX8 F4WG41 A0A182K1J4 A0A182R1T7 A0A2M4ASU7 A0A182W8M2 A0A2M4ATS0 E9IBF1 A0A182L7X6 Q7Q107 W5JSM9 A0A151XBY5 A0A182MNG5 A0A182F334 A0A182PDX2 A0A182VNK5 A0A1Q3FX93 A0A182XHC9 A0A182IFT6 A0A1B6LN91 A0A182TRH4 A0A182Q502 E0VYJ6 U5EVY2 A0A1B0CGQ7 A0A0P4VN67 R4G8N8 A0A0A9X7W3 N6SY90 A0A293LIA4 A0A0V0GCR4 A0A2R5LJ17 A0A069DQI7 A0A023FAC3 A0A1Z5L6V4 A0A1Y1NBM5 A0A1B6DCC3 A0A1B6DHP3 A0A1Y1NHF1 A0A026WIG6 A0A2S2PTI8 J9JLI3 A0A2H8TLY6 A0A2R7WCS7 R7ULS6 C3XZM7 A0A1J1I2V9 A0A0K8TQU3 A0A3S3PER7 A0A3M6UQW2 A0A0P5XN70 A0A0P6J148 A0A131XTL7 V5IGT8 B7PA23 A0A3N0YU36 A0A0K8VWY7 A0A034WF70 W8BWI9 A0A1S3I7X8 A0A1A6GFM2
A0A212ETR4 A0A3S2M2X9 S4NID5 A0A194PFV9 A0A2P8Z751 A0A2J7PR61 A0A0J7KX34 A0A1B6GDJ3 A0A1B6HIG5 A0A023EM62 D6WR32 A0A084VD12 E2AKZ6 A0A1B0DKT5 A0A182IYZ0 A0A232F3E6 K7IQE0 A0A1L8DHG0 A0A154PHA1 A0A195C6J9 A0A195EZZ0 E2BN56 A0A158NT22 A0A182Y657 A0A2A3EQV9 A0A088A0I1 A0A182NNX8 F4WG41 A0A182K1J4 A0A182R1T7 A0A2M4ASU7 A0A182W8M2 A0A2M4ATS0 E9IBF1 A0A182L7X6 Q7Q107 W5JSM9 A0A151XBY5 A0A182MNG5 A0A182F334 A0A182PDX2 A0A182VNK5 A0A1Q3FX93 A0A182XHC9 A0A182IFT6 A0A1B6LN91 A0A182TRH4 A0A182Q502 E0VYJ6 U5EVY2 A0A1B0CGQ7 A0A0P4VN67 R4G8N8 A0A0A9X7W3 N6SY90 A0A293LIA4 A0A0V0GCR4 A0A2R5LJ17 A0A069DQI7 A0A023FAC3 A0A1Z5L6V4 A0A1Y1NBM5 A0A1B6DCC3 A0A1B6DHP3 A0A1Y1NHF1 A0A026WIG6 A0A2S2PTI8 J9JLI3 A0A2H8TLY6 A0A2R7WCS7 R7ULS6 C3XZM7 A0A1J1I2V9 A0A0K8TQU3 A0A3S3PER7 A0A3M6UQW2 A0A0P5XN70 A0A0P6J148 A0A131XTL7 V5IGT8 B7PA23 A0A3N0YU36 A0A0K8VWY7 A0A034WF70 W8BWI9 A0A1S3I7X8 A0A1A6GFM2
Pubmed
19121390
26354079
22651552
22118469
23622113
29403074
+ More
24945155 18362917 19820115 24438588 20798317 28648823 20075255 21347285 25244985 21719571 21282665 20966253 12364791 20920257 23761445 20566863 27129103 25401762 26823975 23537049 26334808 25474469 28528879 28004739 24508170 30249741 23254933 18563158 26369729 30382153 25765539 25348373 24495485
24945155 18362917 19820115 24438588 20798317 28648823 20075255 21347285 25244985 21719571 21282665 20966253 12364791 20920257 23761445 20566863 27129103 25401762 26823975 23537049 26334808 25474469 28528879 28004739 24508170 30249741 23254933 18563158 26369729 30382153 25765539 25348373 24495485
EMBL
BABH01029967
BABH01029968
ODYU01012229
SOQ58429.1
NWSH01001030
PCG73040.1
+ More
GDQN01008474 GDQN01004700 JAT82580.1 JAT86354.1 KQ460045 KPJ18222.1 AK403121 BAM19570.1 AGBW02012531 OWR44883.1 RSAL01000053 RVE50081.1 GAIX01014114 JAA78446.1 KQ459604 KPI92271.1 PYGN01000166 PSN52329.1 NEVH01022633 PNF18825.1 LBMM01002255 KMQ95072.1 GECZ01009282 JAS60487.1 GECU01033219 JAS74487.1 GAPW01003217 JAC10381.1 KQ971354 EFA07012.2 ATLV01011119 KE524642 KFB35856.1 GL440425 EFN65913.1 AJVK01068480 NNAY01001084 OXU25205.1 GFDF01008233 JAV05851.1 KQ434905 KZC11235.1 KQ978205 KYM96489.1 KQ981897 KYN33676.1 GL449385 EFN82818.1 ADTU01025480 KZ288194 PBC33884.1 GL888128 EGI66808.1 GGFK01010528 MBW43849.1 GGFK01010859 MBW44180.1 GL762111 EFZ22141.1 AAAB01008980 ADMH02000277 ETN67146.1 KQ982320 KYQ57808.1 AXCM01008115 GFDL01002983 JAV32062.1 APCN01001644 GEBQ01014850 JAT25127.1 AXCN02002097 DS235845 EEB18452.1 GANO01001673 JAB58198.1 AJWK01011552 GDKW01000533 JAI56062.1 ACPB03018896 GAHY01000647 JAA76863.1 GBHO01030455 GBHO01030454 GBRD01016099 GDHC01019302 GDHC01009111 JAG13149.1 JAG13150.1 JAG49727.1 JAP99326.1 JAQ09518.1 APGK01052199 APGK01052200 APGK01052201 KB741211 KB632263 ENN72759.1 ERL90892.1 GFWV01002849 GFWV01015184 MAA27579.1 GECL01000464 JAP05660.1 GGLE01005360 MBY09486.1 GBGD01002719 JAC86170.1 GBBI01000834 JAC17878.1 GFJQ02003935 JAW03035.1 GEZM01007522 GEZM01007521 GEZM01007518 GEZM01007514 JAV95129.1 GEDC01013964 GEDC01012773 JAS23334.1 JAS24525.1 GEDC01012104 JAS25194.1 GEZM01007515 JAV95127.1 KK107185 QOIP01000012 EZA55763.1 RLU15690.1 GGMR01020029 MBY32648.1 ABLF02022456 GFXV01003358 MBW15163.1 KK854633 PTY17483.1 AMQN01008241 KB302535 ELU04232.1 GG666475 EEN66548.1 CVRI01000039 CRK94648.1 GDAI01000871 JAI16732.1 NCKU01000017 NCKU01000016 RWS17922.1 RWS17941.1 RCHS01000977 RMX55957.1 GDIP01069670 LRGB01000944 JAM34045.1 KZS14534.1 GDIQ01024478 JAN70259.1 GEFM01005152 JAP70644.1 GANP01006112 JAB78356.1 ABJB010482589 ABJB010801276 DS668644 EEC03445.1 RJVU01026577 ROL49709.1 GDHF01008927 JAI43387.1 GAKP01006519 JAC52433.1 GAMC01002973 JAC03583.1 LZPO01097168 OBS64565.1
GDQN01008474 GDQN01004700 JAT82580.1 JAT86354.1 KQ460045 KPJ18222.1 AK403121 BAM19570.1 AGBW02012531 OWR44883.1 RSAL01000053 RVE50081.1 GAIX01014114 JAA78446.1 KQ459604 KPI92271.1 PYGN01000166 PSN52329.1 NEVH01022633 PNF18825.1 LBMM01002255 KMQ95072.1 GECZ01009282 JAS60487.1 GECU01033219 JAS74487.1 GAPW01003217 JAC10381.1 KQ971354 EFA07012.2 ATLV01011119 KE524642 KFB35856.1 GL440425 EFN65913.1 AJVK01068480 NNAY01001084 OXU25205.1 GFDF01008233 JAV05851.1 KQ434905 KZC11235.1 KQ978205 KYM96489.1 KQ981897 KYN33676.1 GL449385 EFN82818.1 ADTU01025480 KZ288194 PBC33884.1 GL888128 EGI66808.1 GGFK01010528 MBW43849.1 GGFK01010859 MBW44180.1 GL762111 EFZ22141.1 AAAB01008980 ADMH02000277 ETN67146.1 KQ982320 KYQ57808.1 AXCM01008115 GFDL01002983 JAV32062.1 APCN01001644 GEBQ01014850 JAT25127.1 AXCN02002097 DS235845 EEB18452.1 GANO01001673 JAB58198.1 AJWK01011552 GDKW01000533 JAI56062.1 ACPB03018896 GAHY01000647 JAA76863.1 GBHO01030455 GBHO01030454 GBRD01016099 GDHC01019302 GDHC01009111 JAG13149.1 JAG13150.1 JAG49727.1 JAP99326.1 JAQ09518.1 APGK01052199 APGK01052200 APGK01052201 KB741211 KB632263 ENN72759.1 ERL90892.1 GFWV01002849 GFWV01015184 MAA27579.1 GECL01000464 JAP05660.1 GGLE01005360 MBY09486.1 GBGD01002719 JAC86170.1 GBBI01000834 JAC17878.1 GFJQ02003935 JAW03035.1 GEZM01007522 GEZM01007521 GEZM01007518 GEZM01007514 JAV95129.1 GEDC01013964 GEDC01012773 JAS23334.1 JAS24525.1 GEDC01012104 JAS25194.1 GEZM01007515 JAV95127.1 KK107185 QOIP01000012 EZA55763.1 RLU15690.1 GGMR01020029 MBY32648.1 ABLF02022456 GFXV01003358 MBW15163.1 KK854633 PTY17483.1 AMQN01008241 KB302535 ELU04232.1 GG666475 EEN66548.1 CVRI01000039 CRK94648.1 GDAI01000871 JAI16732.1 NCKU01000017 NCKU01000016 RWS17922.1 RWS17941.1 RCHS01000977 RMX55957.1 GDIP01069670 LRGB01000944 JAM34045.1 KZS14534.1 GDIQ01024478 JAN70259.1 GEFM01005152 JAP70644.1 GANP01006112 JAB78356.1 ABJB010482589 ABJB010801276 DS668644 EEC03445.1 RJVU01026577 ROL49709.1 GDHF01008927 JAI43387.1 GAKP01006519 JAC52433.1 GAMC01002973 JAC03583.1 LZPO01097168 OBS64565.1
Proteomes
UP000005204
UP000218220
UP000053240
UP000007151
UP000283053
UP000053268
+ More
UP000245037 UP000235965 UP000036403 UP000007266 UP000030765 UP000000311 UP000092462 UP000075880 UP000215335 UP000002358 UP000076502 UP000078542 UP000078541 UP000008237 UP000005205 UP000076408 UP000242457 UP000005203 UP000075884 UP000007755 UP000075881 UP000075900 UP000075920 UP000075882 UP000007062 UP000000673 UP000075809 UP000075883 UP000069272 UP000075885 UP000075903 UP000076407 UP000075840 UP000075902 UP000075886 UP000009046 UP000092461 UP000015103 UP000019118 UP000030742 UP000053097 UP000279307 UP000007819 UP000014760 UP000001554 UP000183832 UP000285301 UP000275408 UP000076858 UP000001555 UP000085678 UP000092124
UP000245037 UP000235965 UP000036403 UP000007266 UP000030765 UP000000311 UP000092462 UP000075880 UP000215335 UP000002358 UP000076502 UP000078542 UP000078541 UP000008237 UP000005205 UP000076408 UP000242457 UP000005203 UP000075884 UP000007755 UP000075881 UP000075900 UP000075920 UP000075882 UP000007062 UP000000673 UP000075809 UP000075883 UP000069272 UP000075885 UP000075903 UP000076407 UP000075840 UP000075902 UP000075886 UP000009046 UP000092461 UP000015103 UP000019118 UP000030742 UP000053097 UP000279307 UP000007819 UP000014760 UP000001554 UP000183832 UP000285301 UP000275408 UP000076858 UP000001555 UP000085678 UP000092124
PRIDE
Interpro
Gene 3D
CDD
ProteinModelPortal
H9J5Y6
A0A2H1WZB3
A0A2A4JNP2
A0A1E1WH74
A0A194RL03
I4DNT0
+ More
A0A212ETR4 A0A3S2M2X9 S4NID5 A0A194PFV9 A0A2P8Z751 A0A2J7PR61 A0A0J7KX34 A0A1B6GDJ3 A0A1B6HIG5 A0A023EM62 D6WR32 A0A084VD12 E2AKZ6 A0A1B0DKT5 A0A182IYZ0 A0A232F3E6 K7IQE0 A0A1L8DHG0 A0A154PHA1 A0A195C6J9 A0A195EZZ0 E2BN56 A0A158NT22 A0A182Y657 A0A2A3EQV9 A0A088A0I1 A0A182NNX8 F4WG41 A0A182K1J4 A0A182R1T7 A0A2M4ASU7 A0A182W8M2 A0A2M4ATS0 E9IBF1 A0A182L7X6 Q7Q107 W5JSM9 A0A151XBY5 A0A182MNG5 A0A182F334 A0A182PDX2 A0A182VNK5 A0A1Q3FX93 A0A182XHC9 A0A182IFT6 A0A1B6LN91 A0A182TRH4 A0A182Q502 E0VYJ6 U5EVY2 A0A1B0CGQ7 A0A0P4VN67 R4G8N8 A0A0A9X7W3 N6SY90 A0A293LIA4 A0A0V0GCR4 A0A2R5LJ17 A0A069DQI7 A0A023FAC3 A0A1Z5L6V4 A0A1Y1NBM5 A0A1B6DCC3 A0A1B6DHP3 A0A1Y1NHF1 A0A026WIG6 A0A2S2PTI8 J9JLI3 A0A2H8TLY6 A0A2R7WCS7 R7ULS6 C3XZM7 A0A1J1I2V9 A0A0K8TQU3 A0A3S3PER7 A0A3M6UQW2 A0A0P5XN70 A0A0P6J148 A0A131XTL7 V5IGT8 B7PA23 A0A3N0YU36 A0A0K8VWY7 A0A034WF70 W8BWI9 A0A1S3I7X8 A0A1A6GFM2
A0A212ETR4 A0A3S2M2X9 S4NID5 A0A194PFV9 A0A2P8Z751 A0A2J7PR61 A0A0J7KX34 A0A1B6GDJ3 A0A1B6HIG5 A0A023EM62 D6WR32 A0A084VD12 E2AKZ6 A0A1B0DKT5 A0A182IYZ0 A0A232F3E6 K7IQE0 A0A1L8DHG0 A0A154PHA1 A0A195C6J9 A0A195EZZ0 E2BN56 A0A158NT22 A0A182Y657 A0A2A3EQV9 A0A088A0I1 A0A182NNX8 F4WG41 A0A182K1J4 A0A182R1T7 A0A2M4ASU7 A0A182W8M2 A0A2M4ATS0 E9IBF1 A0A182L7X6 Q7Q107 W5JSM9 A0A151XBY5 A0A182MNG5 A0A182F334 A0A182PDX2 A0A182VNK5 A0A1Q3FX93 A0A182XHC9 A0A182IFT6 A0A1B6LN91 A0A182TRH4 A0A182Q502 E0VYJ6 U5EVY2 A0A1B0CGQ7 A0A0P4VN67 R4G8N8 A0A0A9X7W3 N6SY90 A0A293LIA4 A0A0V0GCR4 A0A2R5LJ17 A0A069DQI7 A0A023FAC3 A0A1Z5L6V4 A0A1Y1NBM5 A0A1B6DCC3 A0A1B6DHP3 A0A1Y1NHF1 A0A026WIG6 A0A2S2PTI8 J9JLI3 A0A2H8TLY6 A0A2R7WCS7 R7ULS6 C3XZM7 A0A1J1I2V9 A0A0K8TQU3 A0A3S3PER7 A0A3M6UQW2 A0A0P5XN70 A0A0P6J148 A0A131XTL7 V5IGT8 B7PA23 A0A3N0YU36 A0A0K8VWY7 A0A034WF70 W8BWI9 A0A1S3I7X8 A0A1A6GFM2
PDB
4H61
E-value=5.75749e-15,
Score=195
Ontologies
GO
PANTHER
Topology
Subcellular location
Nucleus
Length:
285
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.01639
Exp number, first 60 AAs:
0.00045
Total prob of N-in:
0.02138
outside
1 - 285
Population Genetic Test Statistics
Pi
198.427704
Theta
172.552984
Tajima's D
0.279929
CLR
0.261218
CSRT
0.44192790360482
Interpretation
Uncertain
