Gene

KWMTBOMO15201

Pre Gene Modal

BGIBMGA004964

Annotation

PREDICTED:_transcriptional_adapter_2B_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr25(-):6640205-6646368      View in EpiBrowser

Full name

Transcriptional adapter       + More
Transcriptional adapter 2B      

Alternative Name

dADA2b

Transcription factor

MYB

Location in the cell

Nuclear   Reliability : 3.602

CDS

ATGTCATTTTCAGATCTTTACGCTAAATATAATTGTACATATTGTCAAGAGGAAATAAACGGCGTAAGAGTTAAATGTACTGAATGTGTTGATTTTGATATTTGTTTGCAGTGTTTTTCTCTTGGTGCTGAAATCGGACAGCACAAAAACGATCATTCATATCAGTTTGTGGACTCTGGGGCTTTTGGAATATTTTTAGGACGTAGTAGCTGGTCAGCTAACGAAGAAGTAAGATTATTAGATGCCATAGAACAATTCGGCTTTGGTAACTGGGAGGATATAGCAAAACATATTGAAACAAGAACTCCTGAAGAAGCAAAAGATGAATACATTACTAGGTACCTGGAAGGCACCATAGGCAAAGCAACATGGGGCAATATTGAAAGTACATCTCGCCCATCACTACATTGTGCAGATAAAGATGATGGCCCACTTGGTCCAACTGCAGTGTCTCGACTACCAAACCTAGCTATAACAGTAGACGAAGCAGCACAACTTGGGTATATGCCAAATAGAGATGATTTTGAAAGAGAACATGATCATGAGGCAGAGCAGTTGATCTCAACATTATCATTAAATCCAGAAGATGATGAATTAGATGTTGCACTAAAGCTATCACAAGTTGATATATACATCAGAAGACTGAGAGAGAGAACGAGACGAAAAAGATTAGTTAGAGATTTCCAGTTAGTGTCTGTCTTCTTCAACAATCAGAGGAATAAACAGAAGACCCTAGGAAAACTTGCCAAAGAAAAAAAAGAGTTCACGGAGCGGCTACGATGGATGGCCCAATTCTACGGGCGCGCTGAGCAGGCGTGCGTGTCGAGCGGGCTGTGGCGGGAGCGCGAGCTGCGCGTGCGGCTGGCGGAGCTGCACCGGTACCGGCTGGCCGGCGTCACGCGGCTGGAGGAGTGCGCGCACCACGACCAGCACGCCGCGCTCAGGCGCTCCACGCACCACGACCGGAACGGTAGCAGTGGGTGCCCGGAAACCAATCAGACAAGAGATCAAACATCGATCAACTCGCTGCAGCAAAGAAAAAGAGACGGCGAAAGCGGCTCAAATTCCACCAGCCCAAAGTGCACACGGGACGGAAGTACCGCATGTGGATGCTCCAAAAAGAGCTCATGCAACAGCAACAGCGCAGGATGCTCGAGGAATCTGCTCACCACTAATGAGATACAGTTGTGTTCGGCGTTGAGCCTGCCGCCGGCGCAGTACGTGACGCTGAAGGGCGTGTTGCTCCGCCGAGCGCCCGCGCCCGACTGCGACCTCGACCTCTCCGTCACGCACTACTTGCACGCCGCCGGATGGATACGGAACTAG

Protein

MSFSDLYAKYNCTYCQEEINGVRVKCTECVDFDICLQCFSLGAEIGQHKNDHSYQFVDSGAFGIFLGRSSWSANEEVRLLDAIEQFGFGNWEDIAKHIETRTPEEAKDEYITRYLEGTIGKATWGNIESTSRPSLHCADKDDGPLGPTAVSRLPNLAITVDEAAQLGYMPNRDDFEREHDHEAEQLISTLSLNPEDDELDVALKLSQVDIYIRRLRERTRRKRLVRDFQLVSVFFNNQRNKQKTLGKLAKEKKEFTERLRWMAQFYGRAEQACVSSGLWRERELRVRLAELHRYRLAGVTRLEECAHHDQHAALRRSTHHDRNGSSGCPETNQTRDQTSINSLQQRKRDGESGSNSTSPKCTRDGSTACGCSKKSSCNSNSAGCSRNLLTTNEIQLCSALSLPPAQYVTLKGVLLRRAPAPDCDLDLSVTHYLHAAGWIRN

Description

Required for the function of some acidic activation domains, which activate transcription from a distant site. Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.

Subunit

Interacts with Gcn5 and Ada3 as part of a GCN5-containing ADA multiprotein complex (PubMed:12482983). Associated with a SAGA-type complex that also contains Taf5, e(y)1/Taf9, Taf10, Spt3 and Taf1 (PubMed:12697829).

Keywords

Alternative splicing   Complete proteome   DNA-binding   Metal-binding   Nucleus   Reference proteome   Transcription   Transcription regulation   Zinc   Zinc-finger  

Feature

chain  Transcriptional adapter 2B
splice variant  In isoform A.

Uniprot

A0A2A4JG19   A0A212F744   A0A194PGZ6   A0A194RL76   H9J623   A0A2A4JGD2   + More
A0A067RT11   A0A2J7R553   K7J1E2   A0A154P6B1   A0A232F1X3   A0A182H092   A0A0C9RTN3   A0A0C9RBJ0   A0A310SKC9   A0A0C9RCQ9   A0A2A3EPN6   A0A088AL74   E2CAG1   Q17J17   A0A026VVT0   E2ACN3   A0A151X002   A0A151IQP3   B0WJF7   D6WTS8   A0A1Y1KVP5   A0A139WFG5   Q8I8V0   A0A1W4XDN2   A0A0K8TLB3   A0A023ENK0   B4QYP2   Q8I8V0-2   A0A0B4KFU2   B4HLP3   A0A1I8NBA0   I5ANT8   A0A1I8NBB5   A0A0Q9X563   B4PSM1   A0A0R1E670   A0A0P9ATK8   Q299A8   A0A182MN65   A0A0R3NMD7   B3LZW9   A0A0P8Y1L2   B4NK22   A0A3B0JQ79   A0A1W4W1W8   A0A1B0CMT4   B3NZW3   A0A2M4AWM1   B4JF49   A0A1I8NBA3   Q17J15   Q17J16   A0A2C9GQG4   A0A1W4VQD1   A0A182VDC6   A0A1I8JW23   Q7PQQ9   W8CDD8   A0A3B0JRR0   A0A1L8DX02   W5JW43   A0A182LC52   A0A1L8DWX3   A0A0N0BI82   A0A182R096   A0A0Q9WT02   A0A1I8JW03   F5HKZ2   A0A182TXI8   A0A2M4AUK8   B4M162   A0A2M4AUJ3   W8C9J1   A0A1Q3F7G0   B4K961   A0A1Q3G2E5   A0A2P8YRH3   A0A034VK62   A0A0K8W8L7   A0A1Y1KQ99   A0A0A1WSH4   A0A0K8VB12   A0A1A9YQ64   A0A1B0B2Z1   A0A1A9VDP4   A0A034VK74   A0A1I8NTY5   A0A0K8WF24   A0A0A1WU88   A0A1A9W5P1   A0A1I8NTY2   A0A1Y1KPX8   A0A034VHW0  

Pubmed

22118469    26354079    19121390    24845553    20075255    28648823    + More
26483478    20798317    17510324    24508170    18362917    19820115    28004739    12697829    10731132    12537572    12537569    12482983    26369729    24945155    17994087    12537568    12537573    12537574    16110336    17569856    17569867    25315136    15632085    17550304    12364791    14747013    17210077    24495485    20920257    23761445    20966253    29403074    25348373    25830018   

EMBL

NWSH01001593    PCG70769.1    AGBW02009936    OWR49544.1    KQ459604    KPI92318.1    + More
KQ460045    KPJ18174.1    BABH01029890    PCG70768.1    KK852433    KDR23950.1    NEVH01007395    PNF35964.1    KQ434809    KZC06680.1    NNAY01001210    OXU24725.1    JXUM01100897    KQ564607    KXJ72032.1    GBYB01010911    JAG80678.1    GBYB01004251    JAG74018.1    KQ763472    OAD55041.1    GBYB01010907    JAG80674.1    KZ288209    PBC33001.1    GL453976    EFN75072.1    CH477235    EAT46696.1    KK107790    EZA47770.1    GL438568    EFN68777.1    KQ982625    KYQ53469.1    KQ976755    KYN08562.1    DS231959    EDS29131.1    KQ971352    EFA06279.1    GEZM01077000    JAV63476.1    KYB26672.1    AY142213    AE014297    AY058546    AAL13775.1    AAN52141.1    AAZ52519.1    GDAI01002466    JAI15137.1    GAPW01002606    JAC10992.1    CM000364    EDX13800.1    AGB95749.1    CH480815    EDW43070.1    CM000070    EIM52623.1    CH964272    KRG00178.1    CM000160    EDW96481.1    KRK03172.1    CH902617    KPU80642.1    EAL27795.2    AXCM01000265    KRT00291.1    EDV44159.1    KPU80643.1    EDW85064.1    OUUW01000007    SPP83073.1    AJWK01019156    AJWK01019157    CH954181    EDV49961.1    GGFK01011876    MBW45197.1    CH916369    EDV93330.1    EAT46695.1    EAT46694.1    APCN01002106    AAAB01008879    EAA08449.6    GAMC01002121    JAC04435.1    SPP83072.1    GFDF01003116    JAV10968.1    ADMH02000272    ETN67169.1    GFDF01003117    JAV10967.1    KQ435733    KOX77288.1    AXCN02000226    CH940650    KRF83301.1    EGK96953.1    GGFK01011144    MBW44465.1    EDW67473.1    GGFK01011129    MBW44450.1    GAMC01002119    JAC04437.1    GFDL01011541    JAV23504.1    CH933806    EDW14474.1    GFDL01001073    JAV33972.1    PYGN01000411    PSN46846.1    GAKP01016073    JAC42879.1    GDHF01004892    JAI47422.1    GEZM01077003    JAV63474.1    GBXI01012696    JAD01596.1    GDHF01016246    JAI36068.1    JXJN01007738    GAKP01016058    JAC42894.1    GDHF01002660    JAI49654.1    GBXI01012304    JAD01988.1    GEZM01077005    GEZM01077004    JAV63473.1    GAKP01016056    JAC42896.1   

Proteomes

UP000218220    UP000007151    UP000053268    UP000053240    UP000005204    UP000027135    + More
UP000235965    UP000002358    UP000076502    UP000215335    UP000069940    UP000249989    UP000242457    UP000005203    UP000008237    UP000008820    UP000053097    UP000000311    UP000075809    UP000078542    UP000002320    UP000007266    UP000000803    UP000192223    UP000000304    UP000001292    UP000095301    UP000001819    UP000007798    UP000002282    UP000007801    UP000075883    UP000268350    UP000192221    UP000092461    UP000008711    UP000001070    UP000075840    UP000075903    UP000076407    UP000007062    UP000000673    UP000075882    UP000053105    UP000075886    UP000008792    UP000075902    UP000009192    UP000245037    UP000092443    UP000092460    UP000078200    UP000095300    UP000091820   

PRIDE

H9J623    Q8I8V0   

Pfam

PF00569   ZZ        + More
PF00249   Myb_DNA-binding
PF03392   OS-D

Interpro

IPR000433   Znf_ZZ        + More
IPR016827   Ada2/TADA2       
IPR041983   ADA2-like_ZZ       
IPR009057   Homeobox-like_sf       
IPR017884   SANT_dom       
IPR001005   SANT/Myb       
IPR005055   A10/PebIII       
IPR036682   OS_D_A10/PebIII_sf       

SUPFAM

SSF46689   SSF46689        + More
SSF100910   SSF100910       

Gene 3D

1.10.2080.10    

CDD

cd02335  ZZ_ADA2
cd00167  SANT

ProteinModelPortal

A0A2A4JG19   A0A212F744   A0A194PGZ6   A0A194RL76   H9J623   A0A2A4JGD2   + More
A0A067RT11   A0A2J7R553   K7J1E2   A0A154P6B1   A0A232F1X3   A0A182H092   A0A0C9RTN3   A0A0C9RBJ0   A0A310SKC9   A0A0C9RCQ9   A0A2A3EPN6   A0A088AL74   E2CAG1   Q17J17   A0A026VVT0   E2ACN3   A0A151X002   A0A151IQP3   B0WJF7   D6WTS8   A0A1Y1KVP5   A0A139WFG5   Q8I8V0   A0A1W4XDN2   A0A0K8TLB3   A0A023ENK0   B4QYP2   Q8I8V0-2   A0A0B4KFU2   B4HLP3   A0A1I8NBA0   I5ANT8   A0A1I8NBB5   A0A0Q9X563   B4PSM1   A0A0R1E670   A0A0P9ATK8   Q299A8   A0A182MN65   A0A0R3NMD7   B3LZW9   A0A0P8Y1L2   B4NK22   A0A3B0JQ79   A0A1W4W1W8   A0A1B0CMT4   B3NZW3   A0A2M4AWM1   B4JF49   A0A1I8NBA3   Q17J15   Q17J16   A0A2C9GQG4   A0A1W4VQD1   A0A182VDC6   A0A1I8JW23   Q7PQQ9   W8CDD8   A0A3B0JRR0   A0A1L8DX02   W5JW43   A0A182LC52   A0A1L8DWX3   A0A0N0BI82   A0A182R096   A0A0Q9WT02   A0A1I8JW03   F5HKZ2   A0A182TXI8   A0A2M4AUK8   B4M162   A0A2M4AUJ3   W8C9J1   A0A1Q3F7G0   B4K961   A0A1Q3G2E5   A0A2P8YRH3   A0A034VK62   A0A0K8W8L7   A0A1Y1KQ99   A0A0A1WSH4   A0A0K8VB12   A0A1A9YQ64   A0A1B0B2Z1   A0A1A9VDP4   A0A034VK74   A0A1I8NTY5   A0A0K8WF24   A0A0A1WU88   A0A1A9W5P1   A0A1I8NTY2   A0A1Y1KPX8   A0A034VHW0  

PDB

6CW2     E-value=1.45898e-19,     Score=237

KEGG

101743634    K15127 transcriptional adapter 2-beta | (RefSeq) transcriptional adapter 2B

GO

GO:0008270   GO:0035065   GO:0003677   GO:0006357   GO:0003713   GO:0005634   GO:0006338   GO:0003682   GO:0035066   GO:0070461   GO:0016573   GO:0000124   GO:0005700   GO:0035222   GO:0043966   GO:0006355   GO:2000331   GO:0016740   GO:0016746   GO:0070775   GO:0004402   GO:0006391   GO:0031167   GO:0008408   GO:0005112   GO:0015930  

Subcellular location

Nucleus  

Length:

441

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.000940000000000001

Exp number, first 60 AAs:

0.0002

Total prob of N-in:

0.00431

outside

1  -  441

 

 

Pi

284.425687

Theta

188.853458

Tajima's D

1.594244

CLR

0.00581

CSRT

0.80265986700665

Interpretation

Uncertain