Gene

KWMTBOMO15145

Pre Gene Modal

BGIBMGA004986

Annotation

PREDICTED:_protein_farnesyltransferase_subunit_beta_[Bombyx_mori]

Location

Bomo_Chr25(-):5802231-5809073      View in EpiBrowser

Full name

Protein farnesyltransferase subunit beta      

Location in the cell

Cytoplasmic   Reliability : 1.259 Extracellular   Reliability : 1.581

CDS

ATGGAAAACCAAGTCCGTTGTTACAACGATATTGTATCGGAAGCTTTCGATTCTGAAGATGTTAAAACAGACACATCAATAGATCAGATTTATGTTGAAAAAACAATTTTGAAATTGTACAAGGAATTTGAGAAAAATTCCTCCATTGATCCTGATTTACCACTTTTGATAAAAGAAGTTCACAGCAAGCTATTAAAAAAATGTTTAATCAATTTGCCAAAAAGTTATGAATGCCTTGATGCTAGCAGAACCTGGATCATATATTGGATTCTACATTCACTATGGATTCTTAATGACATGCCCGACCATGAGACTCTTTCTGCAGTAGTAAAATTCTTAGATCAGTGTCAACATGAAGATGGCGGTTATGGTGGGGGGCCTAGACAATATCCACATTTGGGAACAACATATGCAGCTGTTAACGCCCTTAGCATAATAGGAACAGATGAGGCTTATGACTCAATAGATAGAAGTAGCTTACAAAGATTTCTGTGGACAGTTAGAGATGTTGATGGATCCTTTGCTCTTCATAAAGATGGAGAACAAGATATTAGAGGCGCATATTGTGCAATTAGTATAGCCAAAATGACAAATACATACACAGAAGCGTTATTTGATAAAACGGCAGAATGGATTGTTAGTTGTCAGACATATGAGGGTGGCTTTGCTGGTTGTCCTGGTATGGAAGCACATGGTGGCTATGCATTCTGTGGAATCGCATCCTTAGCTCTATTAAATAGAACACAATTATGTGATATAGATTCACTGCTTAGGTGGTCAGTAAACAGACAGATGAGGATAGAGGGTGGATTTCAAGGAAGGACAAACAAACTTGTAGATGGATGTTATTCTTTTTGGCAAGGTGCTGCTTTTCCTATTATAAGTGCAATACTTTCAAAAGATAATAAGGAACTTATTGAGACAGTTCTTTTCAATCAATCTGCCCTACAGGAATACATTTTGATATGTTGTCAAAATCGGGATGGTGGTCTGATTGATAAGCCTGGCAAGCCTAGAGACATTTACCATACATGTTATGGCCTCAGTGGATTATCGGTAGCGCAACATGGTACAGGGGTTATGGATCCCTACGTAGTTGGATCACCTAGTAATGAACTGAATAGAGTGCATCCTTTGCATAATGTTGCACCTCATTTGGTTTACAACAGTGTTCACTATTTTATCAGGCACCCGCCTCCAGTCAAAGACAAGAATTAA

Protein

MENQVRCYNDIVSEAFDSEDVKTDTSIDQIYVEKTILKLYKEFEKNSSIDPDLPLLIKEVHSKLLKKCLINLPKSYECLDASRTWIIYWILHSLWILNDMPDHETLSAVVKFLDQCQHEDGGYGGGPRQYPHLGTTYAAVNALSIIGTDEAYDSIDRSSLQRFLWTVRDVDGSFALHKDGEQDIRGAYCAISIAKMTNTYTEALFDKTAEWIVSCQTYEGGFAGCPGMEAHGGYAFCGIASLALLNRTQLCDIDSLLRWSVNRQMRIEGGFQGRTNKLVDGCYSFWQGAAFPIISAILSKDNKELIETVLFNQSALQEYILICCQNRDGGLIDKPGKPRDIYHTCYGLSGLSVAQHGTGVMDPYVVGSPSNELNRVHPLHNVAPHLVYNSVHYFIRHPPPVKDKN

Description

Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.

Catalytic Activity

(2E,6E)-farnesyl diphosphate + L-cysteinyl-[protein] = diphosphate + S-(2E,6E)-farnesyl-L-cysteinyl-[protein]

Cofactor

Zn(2+)

Subunit

Heterodimer of an alpha and a beta subunit.

Similarity

Belongs to the protein prenyltransferase subunit beta family.
Belongs to the cyclin family.

Feature

chain  Protein farnesyltransferase subunit beta

Uniprot

E2QC37   A0A2A4JM34   A0A2H1WZI3   A0A212ETQ7   A0A1E1WE49   A0A194PGV1   + More
A0A0L7KSY6   A0A194RLC8   A0A067R136   A0A2J7QAW9   A0A1W4XHW9   A0A0L0CJJ2   A0A1B6CPL5   A0A336MDZ1   A0A1Y1L156   A0A1A9WH29   D3TP88   A0A1A9YCT7   A0A1A9Z3U9   A0A1B0G9M1   A0A1B6HD43   A0A1B0BUH6   A0A0A1WJA9   A0A034V7Z1   A0A0K8UKP2   A0A1B6EPX8   A0A293N1C3   A0A224Z2A8   R7UM01   T1PC76   A0A1B6L534   W8BQ94   A0A131YYF3   A0A2R5LKX7   A0A1B6DT40   L7M4M2   A0A1S3HPM9   A0A2R2WSJ4   A0A1I8P731   A0A1Z5LCF7   D6WSN3   A0A1A9V7X0   E2ANE8   A0A151IQ29   A0A2H8TSE4   E0VV79   A0A2G8LR97   A0A2S2N6U6   J3JUW9   V3YZC1   E9IZL7   A0A151I3F7   A0A1J1IWT7   A0A151J5R8   A0A158NIN8   J9K4H2   B4LWX0   U4U0Q3   N6TVJ2   B4KBZ8   A0A2S2R6M8   A0A232F293   A0A131XVC9   A0A147BQI4   A0A195FS92   A0A1Q3G1T2   A0A3L8DJT5   A0A026WM91   A0A2C9L7R8   A0A182QI73   A0A1E1X5D9   I3JEI6   A0A182PSH7   A0A0M4F6L4   A0A1L8DTT6   E2BEM9   A0A3B4EQF7   A0A3Q2VTU3   A0A3P8RBP7   A0A3P9B2C7   A0A084VXQ9   A0A3Q4FZZ4   U5EHI4   A0A0P4W3G2   A0A088AFG0   Q4RQW7   A0A0P4Z5Y7   A0A0P6EEN8   A0A0P5T528   A0A0P5RLT1   A0A182NRS6   H3DG66   A0A310SCJ8   A0A164T713   A0A2M4APS2   A0A3S1B2Q5   B4IBW2   A0A182VBP7   B4QX36   A0A2M4AQ49  

EC Number

2.5.1.58

Pubmed

19121390    22118469    26354079    26227816    24845553    26108605    + More
28004739    20353571    25830018    25348373    28797301    23254933    25315136    24495485    26830274    25576852    28528879    18362917    19820115    20798317    20566863    29023486    22516182    21282665    21347285    17994087    23537049    28648823    29652888    30249741    24508170    15562597    28503490    25186727    24438588    15496914   

EMBL

BABH01029968    BABH01029969    AB201556    BAD89510.1    NWSH01001030    PCG73041.1    + More
ODYU01012229    SOQ58428.1    AGBW02012531    OWR44885.1    GDQN01005923    JAT85131.1    KQ459604    KPI92268.1    JTDY01006181    KOB66215.1    KQ460045    KPJ18224.1    KK853013    KDR12520.1    NEVH01016310    PNF25731.1    JRES01000301    KNC32583.1    GEDC01021928    JAS15370.1    UFQT01000693    SSX26607.1    GEZM01067832    JAV67393.1    EZ423240    ADD19516.1    CCAG010022856    GECU01035103    JAS72603.1    JXJN01020692    GBXI01015148    JAC99143.1    GAKP01019526    JAC39426.1    GDHF01025178    JAI27136.1    GECZ01029772    JAS39997.1    GFWV01021441    MAA46169.1    GFPF01010953    MAA22099.1    AMQN01007169    KB300141    ELU07098.1    KA645538    AFP60167.1    GEBQ01021236    JAT18741.1    GAMC01007582    GAMC01007580    JAB98973.1    GEDV01004338    JAP84219.1    GGLE01006054    MBY10180.1    GEDC01008473    JAS28825.1    GACK01006961    JAA58073.1    KY628458    ARE68914.1    GFJQ02001975    JAW04995.1    KQ971354    EFA07131.1    GL441193    EFN65048.1    KQ976794    KYN08259.1    GFXV01004707    MBW16512.1    DS235804    EEB17285.1    MRZV01000007    PIK62700.1    GGMR01000179    MBY12798.1    BT127034    AEE61996.1    KB203660    ESO83518.1    GL767232    EFZ13918.1    KQ976479    KYM83776.1    CVRI01000059    CRL03017.1    KQ979945    KYN18574.1    ADTU01017033    ABLF02028179    CH940650    EDW66691.1    KB631951    ERL87434.1    APGK01016859    APGK01016860    APGK01016861    APGK01016862    APGK01016863    KB739988    ENN82053.1    CH933806    EDW15850.1    GGMS01016452    MBY85655.1    NNAY01001181    OXU24831.1    GEFM01004543    JAP71253.1    GEGO01002632    JAR92772.1    KQ981285    KYN43167.1    GFDL01001292    JAV33753.1    QOIP01000007    RLU20657.1    KK107152    EZA57177.1    AXCN02001149    GFAC01004734    JAT94454.1    AERX01015206    CP012526    ALC47712.1    GFDF01004205    JAV09879.1    GL447829    EFN85863.1    ATLV01018182    KE525221    KFB42753.1    GANO01003009    JAB56862.1    GDRN01092204    JAI60150.1    CAAE01015003    CAG09215.1    GDIP01219978    JAJ03424.1    GDIQ01063705    JAN31032.1    GDIQ01096446    JAL55280.1    GDIQ01098945    GDIP01086614    JAL52781.1    JAM17101.1    KQ777939    OAD52037.1    LRGB01001867    KZS10239.1    GGFK01009463    MBW42784.1    RQTK01000919    RUS73593.1    CH480827    EDW44870.1    CM000364    EDX12690.1    GGFK01009417    MBW42738.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000037510    UP000053240    + More
UP000027135    UP000235965    UP000192223    UP000037069    UP000091820    UP000092443    UP000092445    UP000092444    UP000092460    UP000014760    UP000095301    UP000085678    UP000095300    UP000007266    UP000078200    UP000000311    UP000078542    UP000009046    UP000230750    UP000030746    UP000078540    UP000183832    UP000078492    UP000005205    UP000007819    UP000008792    UP000030742    UP000019118    UP000009192    UP000215335    UP000078541    UP000279307    UP000053097    UP000076420    UP000075886    UP000005207    UP000075885    UP000092553    UP000008237    UP000261460    UP000264840    UP000265100    UP000265160    UP000030765    UP000261580    UP000005203    UP000075884    UP000007303    UP000076858    UP000271974    UP000001292    UP000075903    UP000000304   

PRIDE

E2QC37   

Pfam

PF00432   Prenyltrans        + More
PF00134   Cyclin_N

Interpro

IPR026872   FTB        + More
IPR008930   Terpenoid_cyclase/PrenylTrfase       
IPR001330   PFTB_repeat       
IPR006671   Cyclin_N       
IPR013763   Cyclin-like       
IPR036915   Cyclin-like_sf       

SUPFAM

SSF48239   SSF48239        + More
SSF47954   SSF47954       

CDD

cd02893  FTase
cd00043  CYCLIN

ProteinModelPortal

E2QC37   A0A2A4JM34   A0A2H1WZI3   A0A212ETQ7   A0A1E1WE49   A0A194PGV1   + More
A0A0L7KSY6   A0A194RLC8   A0A067R136   A0A2J7QAW9   A0A1W4XHW9   A0A0L0CJJ2   A0A1B6CPL5   A0A336MDZ1   A0A1Y1L156   A0A1A9WH29   D3TP88   A0A1A9YCT7   A0A1A9Z3U9   A0A1B0G9M1   A0A1B6HD43   A0A1B0BUH6   A0A0A1WJA9   A0A034V7Z1   A0A0K8UKP2   A0A1B6EPX8   A0A293N1C3   A0A224Z2A8   R7UM01   T1PC76   A0A1B6L534   W8BQ94   A0A131YYF3   A0A2R5LKX7   A0A1B6DT40   L7M4M2   A0A1S3HPM9   A0A2R2WSJ4   A0A1I8P731   A0A1Z5LCF7   D6WSN3   A0A1A9V7X0   E2ANE8   A0A151IQ29   A0A2H8TSE4   E0VV79   A0A2G8LR97   A0A2S2N6U6   J3JUW9   V3YZC1   E9IZL7   A0A151I3F7   A0A1J1IWT7   A0A151J5R8   A0A158NIN8   J9K4H2   B4LWX0   U4U0Q3   N6TVJ2   B4KBZ8   A0A2S2R6M8   A0A232F293   A0A131XVC9   A0A147BQI4   A0A195FS92   A0A1Q3G1T2   A0A3L8DJT5   A0A026WM91   A0A2C9L7R8   A0A182QI73   A0A1E1X5D9   I3JEI6   A0A182PSH7   A0A0M4F6L4   A0A1L8DTT6   E2BEM9   A0A3B4EQF7   A0A3Q2VTU3   A0A3P8RBP7   A0A3P9B2C7   A0A084VXQ9   A0A3Q4FZZ4   U5EHI4   A0A0P4W3G2   A0A088AFG0   Q4RQW7   A0A0P4Z5Y7   A0A0P6EEN8   A0A0P5T528   A0A0P5RLT1   A0A182NRS6   H3DG66   A0A310SCJ8   A0A164T713   A0A2M4APS2   A0A3S1B2Q5   B4IBW2   A0A182VBP7   B4QX36   A0A2M4AQ49  

PDB

3E37     E-value=1.43518e-109,     Score=1013

KEGG

692537    K05954 protein farnesyltransferase subunit beta [EC:2.5.1.58] | (RefSeq) Fntb; farnesyltransferase,

PATHWAY

00900    Terpenoid backbone biosynthesis - Bombyx mori (domestic silkworm)

GO

GO:0005965   GO:0008270   GO:0018343   GO:0004660   GO:0018342   GO:0003824   GO:0003231   GO:0016021   GO:0042127   GO:0005525   GO:0000166   GO:0003677   GO:0008408   GO:0005112   GO:0015930  

PANTHER

PTHR11774:SF6  

Length:

405

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.14177

Exp number, first 60 AAs:

0

Total prob of N-in:

0.05286

outside

1  -  405

 

 

Pi

292.31582

Theta

173.696906

Tajima's D

1.818438

CLR

0.05395

CSRT

0.853557322133893

Interpretation

Uncertain