| Gene | Short Name | Full Name |
|---|---|---|
| KWMTBOMO02384 | ||
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Description
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02385 (BGIBMGA013539) | ||
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Description
PREDICTED:_hairy/enhancer-of-split_related_with_YRPW_motif_protein_[Amyelois_transitella]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02403 (BGIBMGA013531) |
Obscurin
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Muscle M-line assembly protein unc-89 Kalirin Triple functional domain protein |
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Description
Structural component of the muscle M line which is involved in assembly and organization of sarcomere (PubMed:22467859, PubMed:26251439). Required for the development and organization of indirect flight muscle sarcomeres by regulating the formation of M line and H zone and the correct assembly of thick and thin filaments in the sarcomere (PubMed:22467859, PubMed:26251439). Likely to have serine/threonine-protein kinase activity as one of the two protein kinase domains appears to be functional (Probable).
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Structural component of the muscle M line which is involved in assembly and organization of sarcomere myofilaments (PubMed:15313609, PubMed:16453163, PubMed:18801371, PubMed:22621901, PubMed:23283987, PubMed:27009202). The large isoform a, isoform b, isoform d and isoform f play an essential role in maintaining the organization of sarcomeres but not myofilament alignment during body wall muscle development whereas the small isoform c and isoform d appear to have a minor role (PubMed:15313609, PubMed:16453163, PubMed:22768340). Isoform b and isoform f are required for the organization of unc-15/paramyosin into sarcomere thick filaments in body wall muscles (PubMed:27009202). By binding mel-26, a substrate adapter of the cul-3 E3 ubiquitin-protein ligase complex, regulates the organization of myosin thick filaments, likely by preventing the degradation of microtubule severing protein mei-1 (PubMed:22621901). Acts as guanine nucleotide exchange factor (GEF) for Rho GTPase rho-1 but not ced-10, mig-2 and cdc-42 (PubMed:18801371). The large isoforms regulate Ca(2+) signaling during muscle contraction by ensuring the correct localization of sarco-endoplamic reticulum Ca(2+) ATPase sca-1 and ryanodine receptor unc-68 (PubMed:22768340). By controlling the contraction and/or organization of pharyngeal muscles, plays a role in the formation of pharyngeal gland cell extension (PubMed:21868609). In contrast to obscurins in other species, unlikely to have serine/threonine kinase activity as both protein kinase domains are predicted to be catalytically inactive (Probable). Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity. Isoforms 1 and 7 are necessary for neuronal development and axonal outgrowth. Isoform 6 is required for dendritic spine formation. Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity (By similarity). Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity. Structural component of striated muscles which plays a role in myofibrillogenesis. Probably involved in the assembly of myosin into sarcomeric A bands in striated muscle (By similarity). Has serine/threonine protein kinase activity and phosphorylates N-cadherin CDH2 and sodium/potassium-transporting ATPase subunit ATP1B1 (PubMed:23392350). Binds (via the PH domain) strongly to phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), and to a lesser extent to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), phosphatidylinositol 5-phosphate (PtdIns(5)P) and phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) (By similarity). Isoform 2 and isoform 3: bind phosphatidylinositol bisphosphates (PIP2s) via their PH domains and negatively regulate the PI3K/AKT/mTOR signaling pathway, thus contributing to the regulation of cardiomyocyte size and adhesion. Structural component of striated muscles which plays a role in myofibrillogenesis. Probably involved in the assembly of myosin into sarcomeric A bands in striated muscle (PubMed:11448995, PubMed:16205939). Has serine/threonine protein kinase activity and phosphorylates N-cadherin CDH2 and sodium/potassium-transporting ATPase subunit ATP1B1 (By similarity). Binds (via the PH domain) strongly to phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), and to a lesser extent to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), phosphatidylinositol 5-phosphate (PtdIns(5)P) and phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) (PubMed:28826662). Promotes the exchange of GDP by GTP. Together with leukocyte antigen-related (LAR) protein, it could play a role in coordinating cell-matrix and cytoskeletal rearrangements necessary for cell migration and cell growth (By similarity). |
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02404 (BGIBMGA013530) | ||
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Description
P:regulation of Rho protein signal transduction
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02405 | ||
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Description
P:DNA integration
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02406 (BGIBMGA013529) | ||
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Description
consensus disorder prediction
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02407 (BGIBMGA012097) | ||
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Description
C:integral component of membrane
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02408 | ||
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Description
F:RNA-directed DNA polymerase activity
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02409 (BGIBMGA013526) |
Proteasome subunit beta
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Description
proteasome_beta_2_subunit-like_protein_[Danaus_plexippus]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02410 | ||
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Description
C:integral component of membrane
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02411 |
RNA-directed DNA polymerase from mobile element jockey
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Description
PREDICTED:_RNA-directed_DNA_polymerase_from_mobile_element_jockey-like_[Plutella_xylostella]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02412 |
RNA-directed DNA polymerase from mobile element jockey
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Description
PREDICTED:_RNA-directed_DNA_polymerase_from_mobile_element_jockey-like_[Plutella_xylostella]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02413 (BGIBMGA013489) | ||
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Description
consensus disorder prediction
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02414 (BGIBMGA013522) |
Queuosine salvage protein
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Description
Involved in salvaging queuosine.
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||
| KWMTBOMO02415 (BGIBMGA013491) | ||
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Description
PREDICTED:_nucleoporin_Nup43_[Amyelois_transitella]
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| Gene Information Genome Browser Gene Ontology and Pathway Transcriptional Analysis View Epigenomics Data Protein Structure Population genetics Close | ||