Gene

KWMTBOMO02409

Pre Gene Modal

BGIBMGA013526

Annotation

proteasome_beta_2_subunit-like_protein_[Danaus_plexippus]

Location

Bomo_Chr5(-):1480380-1487307      View in EpiBrowser

Full name

Proteasome subunit beta      

Location in the cell

Extracellular   Reliability : 1.864

CDS

ATGACGAATCCTTCAACTTCTTTGTATTTGCAATGTCTCATCGGGATTCAGTGTCAGGACTTCGTGTTGGTAGCCGCAGACCAGACAAATATACAGAGTATTATCGTCATGAGCGACGACGAGGATAAGCTCCACAACATTTCGAATAGTCTTGTAATGGGAGTTATAGGAGATCACGCTGATGCGGTACATTTGCAGCAGTACATTACCAAGAACTTGCAGTTGTACAAGCTGAAGAACGGATACGAGTTGGATACGCCTGCCGTGGTCCATTTCACAAGGAGGACCCTGTCTGATAGTTTGAAGAATGGCAATCCTACGATGGTGAATATGCTATTAGCTGGTTATGATAGGAACACAGGCAGTGCACTATACGCCCTGGACTTCTTGGCTTCTTGCGTCAAAGTGCCGTACGCTGTCCACGGCTTCGGAGGCATCATCAGCTTGGGTATCCTGGATGACCTCTACAGACCAACGTTATCGCAAACAGAAGCTTACGAAGTATTGAAAATTTGCATCAGGGAAATACAGAAGAGACTGTTTGCTAATTTGAAGAATTTCCAAGTTAAGATTGTGTCTAGATGCGGCATCAAGACTCTGCCGACGATAAACGCAGATACTTTTAGTAAATAA

Protein

MTNPSTSLYLQCLIGIQCQDFVLVAADQTNIQSIIVMSDDEDKLHNISNSLVMGVIGDHADAVHLQQYITKNLQLYKLKNGYELDTPAVVHFTRRTLSDSLKNGNPTMVNMLLAGYDRNTGSALYALDFLASCVKVPYAVHGFGGIISLGILDDLYRPTLSQTEAYEVLKICIREIQKRLFANLKNFQVKIVSRCGIKTLPTINADTFSK

Catalytic Activity

Cleavage of peptide bonds with very broad specificity.

Subunit

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

Similarity

Belongs to the peptidase T1B family.

Feature

chain  Proteasome subunit beta

Uniprot

A0A2H1V2W2   A0A2W1BKD8   A0A212F5L6   A0A2A4JXW0   A0A2H1VJ26   S4PBF7   + More
A0A2A4K3Q1   A0A194RRH8   A0A2W1BRR4   A0A194PIK4   A0A1E1WQZ4   A0A232EMC0   K7J9Q1   A0A026X561   A0A151XHU4   A0A151IML7   E9IB35   A0A151HY76   A0A195ESA4   A0A158NVX6   A0A0P5WU15   A0A0P5YD11   A0A0P5Q8R2   A0A067R3P7   F4X4Y2   A0A2J7PHZ7   A0A0P5Z5F8   A0A0N8AXZ3   A0A194Q5N8   A0A0P5QF09   A0A0P5M4S4   A0A0P5QKR7   A0A0P5A981   A0A0N8DTF6   A0A0N8C7G3   A0A0P6ILM8   E9HF20   A0A087ZWB2   E2BY51   A0A2A3EMN4   A0A0L7QVH1   A0A0N8BRN9   A0A0P5NJY9   A0A154PNC2   A0A310SF94   A0A0P5YST0   A0A0P5THG0   A0A0N0BEU3   A0A0P5NWN9   A0A1B6E889   A0A1Y1NKF7   A0A212FCC9   A0A1W4WMT1   J3JU85   A0A0P5TVH2   A2IAA2   D6WPM7   A0A1Z5LEK4   E0VWC5   V5GZQ3   A0A293MNJ5   A0A2R5LE76   A0A1E1X5E0   K1PDC6   A0A023FU65   A0A1S3J3M5   R7THR9   A0A0P6D0D8   A0A2B4RU76   H3B8Y0   A0A0P5NGD4   A0A131YV56   A0A1S4EGJ4   A0A224YQ14   A0A224YS56   A0A034VAR8   A0A336JWZ1   T1J2E8   A0A0K8VWQ3   W8BZZ6   B0W1D3   A0A0X3PVZ5   A0A1Q3FDP7   V4BCA6   C1BZW6   A0A2S2NCF7   A0A1L8DSZ6   B3MU93   T1EYD7   U3FWB4   Q17IE3   C4WW19   A0A0K8S7L4   C4WU68   Q86F39   A0A0R3UKQ4   A0A0K8R840   A0A0K8TSM5  

EC Number

3.4.25.1

Pubmed

28756777    22118469    23622113    26354079    28648823    20075255    + More
24508170    30249741    21282665    21347285    24845553    21719571    21292972    20798317    28004739    22516182    23537049    17437641    18362917    19820115    28528879    20566863    28503490    22992520    23254933    9215903    26830274    28797301    25348373    24495485    17994087    23915248    17510324    12973349    26369729   

EMBL

ODYU01000215    SOQ34614.1    KZ150214    PZC72143.1    AGBW02010179    OWR49026.1    + More
NWSH01000405    PCG76649.1    ODYU01002848    SOQ40839.1    GAIX01005932    JAA86628.1    NWSH01000165    PCG78887.1    KQ459765    KPJ20072.1    KZ149920    PZC77769.1    KQ459604    KPI92554.1    GDQN01001803    JAT89251.1    NNAY01003382    OXU19505.1    AAZX01001624    KK107020    QOIP01000006    EZA62569.1    RLU21138.1    KQ982129    KYQ59858.1    KQ977033    KYN06198.1    GL762106    EFZ22229.1    KQ976730    KYM76394.1    KQ981993    KYN31130.1    ADTU01027584    GDIP01081769    JAM21946.1    GDIP01059470    JAM44245.1    GDIQ01139143    JAL12583.1    KK852779    KDR16684.1    GL888679    EGI58555.1    NEVH01025130    PNF15952.1    GDIP01061421    JAM42294.1    GDIQ01231915    JAK19810.1    KQ459465    KPJ00320.1    GDIQ01121404    JAL30322.1    GDIQ01184930    GDIQ01180584    GDIQ01046076    JAK66795.1    GDIQ01112850    JAL38876.1    GDIP01205751    JAJ17651.1    GDIP01002599    LRGB01003216    JAN01117.1    KZS03717.1    GDIQ01107355    JAL44371.1    GDIQ01019830    JAN74907.1    GL732633    EFX69663.1    GL451420    EFN79330.1    KZ288215    PBC32532.1    KQ414727    KOC62491.1    GDIQ01151547    JAL00179.1    GDIQ01141148    JAL10578.1    KQ434978    KZC12964.1    KQ769068    OAD52975.1    GDIP01055077    JAM48638.1    GDIP01127812    JAL75902.1    KQ435821    KOX72411.1    GDIQ01136649    JAL15077.1    GEDC01003147    JAS34151.1    GEZM01000453    GEZM01000452    JAV98413.1    AGBW02009208    OWR51367.1    APGK01054913    BT126798    KB741253    KB632340    AEE61760.1    ENN71815.1    ERL92957.1    GDIP01121413    JAL82301.1    EF179416    ABM55422.1    KQ971354    EFA06200.1    GFJQ02001134    JAW05836.1    DS235818    EEB17681.1    GALX01002473    JAB65993.1    GFWV01022540    MAA47267.1    GGLE01003714    MBY07840.1    GFAC01004698    JAT94490.1    JH815987    EKC21877.1    GBBL01001959    JAC25361.1    AMQN01012817    KB309774    ELT93338.1    GDIQ01087066    JAN07671.1    LSMT01000344    PFX19805.1    AFYH01014206    AFYH01014207    AFYH01014208    AFYH01014209    AFYH01014210    AFYH01014211    AFYH01014212    GDIQ01149196    JAL02530.1    GEDV01006152    JAP82405.1    GFPF01005505    MAA16651.1    GFPF01005504    MAA16650.1    GAKP01020077    JAC38875.1    UFQS01000002    UFQT01000002    SSW96721.1    SSX17108.1    JH431802    GDHF01009314    JAI43000.1    GAMC01007627    GAMC01007624    JAB98931.1    DS231821    EDS45003.1    GEEE01007396    UYSU01039927    JAP55829.1    VDM01806.1    GFDL01009406    JAV25639.1    KB199650    ESP05311.1    BT080145    ACO14569.1    GGMR01002254    MBY14873.1    GFDF01004577    JAV09507.1    CH902624    EDV33422.1    AMQM01002525    KB095812    ESO11681.1    GAEP01001210    GBEW01000752    JAB53611.1    JAI09613.1    CH477240    EAT46434.1    AK341797    AK342810    BAH72089.1    GBRD01016548    JAG49278.1    AK340931    BAH71438.1    AY223025    FN315002    FN315003    FN320033    FN320034    FN320035    AAP06048.1    CAX70734.1    UXSR01005470    VDD82195.1    GADI01006476    JAA67332.1    GDAI01000480    JAI17123.1   

Proteomes

UP000007151    UP000218220    UP000053240    UP000053268    UP000215335    UP000002358    + More
UP000053097    UP000279307    UP000075809    UP000078542    UP000078540    UP000078541    UP000005205    UP000027135    UP000007755    UP000235965    UP000076858    UP000000305    UP000005203    UP000008237    UP000242457    UP000053825    UP000076502    UP000053105    UP000192223    UP000019118    UP000030742    UP000007266    UP000009046    UP000005408    UP000085678    UP000014760    UP000225706    UP000008672    UP000079169    UP000002320    UP000050788    UP000275846    UP000030746    UP000007801    UP000015101    UP000008820    UP000046399    UP000267029   

PRIDE

A0A087ZWB2   

Pfam

PF00227   Proteasome

Interpro

IPR001353   Proteasome_sua/b        + More
IPR023333   Proteasome_suB-type       
IPR029055   Ntn_hydrolases_N       
IPR016050   Proteasome_bsu_CS       
IPR035206   Proteasome_beta2       

SUPFAM

SSF56235   SSF56235       

Gene 3D

3.60.20.10    

CDD

cd03758  proteasome_beta_type_2

ProteinModelPortal

A0A2H1V2W2   A0A2W1BKD8   A0A212F5L6   A0A2A4JXW0   A0A2H1VJ26   S4PBF7   + More
A0A2A4K3Q1   A0A194RRH8   A0A2W1BRR4   A0A194PIK4   A0A1E1WQZ4   A0A232EMC0   K7J9Q1   A0A026X561   A0A151XHU4   A0A151IML7   E9IB35   A0A151HY76   A0A195ESA4   A0A158NVX6   A0A0P5WU15   A0A0P5YD11   A0A0P5Q8R2   A0A067R3P7   F4X4Y2   A0A2J7PHZ7   A0A0P5Z5F8   A0A0N8AXZ3   A0A194Q5N8   A0A0P5QF09   A0A0P5M4S4   A0A0P5QKR7   A0A0P5A981   A0A0N8DTF6   A0A0N8C7G3   A0A0P6ILM8   E9HF20   A0A087ZWB2   E2BY51   A0A2A3EMN4   A0A0L7QVH1   A0A0N8BRN9   A0A0P5NJY9   A0A154PNC2   A0A310SF94   A0A0P5YST0   A0A0P5THG0   A0A0N0BEU3   A0A0P5NWN9   A0A1B6E889   A0A1Y1NKF7   A0A212FCC9   A0A1W4WMT1   J3JU85   A0A0P5TVH2   A2IAA2   D6WPM7   A0A1Z5LEK4   E0VWC5   V5GZQ3   A0A293MNJ5   A0A2R5LE76   A0A1E1X5E0   K1PDC6   A0A023FU65   A0A1S3J3M5   R7THR9   A0A0P6D0D8   A0A2B4RU76   H3B8Y0   A0A0P5NGD4   A0A131YV56   A0A1S4EGJ4   A0A224YQ14   A0A224YS56   A0A034VAR8   A0A336JWZ1   T1J2E8   A0A0K8VWQ3   W8BZZ6   B0W1D3   A0A0X3PVZ5   A0A1Q3FDP7   V4BCA6   C1BZW6   A0A2S2NCF7   A0A1L8DSZ6   B3MU93   T1EYD7   U3FWB4   Q17IE3   C4WW19   A0A0K8S7L4   C4WU68   Q86F39   A0A0R3UKQ4   A0A0K8R840   A0A0K8TSM5  

PDB

6EPF     E-value=2.91197e-45,     Score=455

KEGG

101742539    K02734 20S proteasome subunit beta 4 [EC:3.4.25.1] | (RefSeq) proteasome subunit beta type-2-like

PATHWAY

03050    Proteasome - Bombyx mori (domestic silkworm)

GO

GO:0004298   GO:0051603   GO:0005839   GO:0005737   GO:0005634   GO:0010499   GO:0043161   GO:0004175   GO:0010498   GO:0032504   GO:0005089   GO:0035023   GO:0006289   GO:0004518   GO:0006281   GO:0048384  

PANTHER

PTHR11599:SF6  

Subcellular location

Cytoplasm  
Nucleus  

Length:

210

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.602439999999999

Exp number, first 60 AAs:

0.05091

Total prob of N-in:

0.06241

outside

1  -  210

 

 

Pi

162.847866

Theta

135.097351

Tajima's D

0.616336

CLR

0.238014

CSRT

0.552422378881056

Interpretation

Uncertain