Gene

KWMTBOMO13837

Pre Gene Modal

BGIBMGA011565

Annotation

PREDICTED:_transcription_factor_collier_[Amyelois_transitella]

Location

Bomo_Chr23(+):10542956-10606747      View in EpiBrowser

Full name

Transcription factor collier      

Alternative Name

Transcription factor knot

Transcription factor

COE

Location in the cell

Nuclear   Reliability : 3.333

CDS

ATGTTCGGGCTCCACCACCAGGAGGCGGCTGGTGGTCTCCATGCCCAACCTCGAGGACCCGTCACCTCTCTCAAAGAAGAACCGCTTACACGAGCATGGATGACTCCGAGTTCCTTAGTTGATAATACGAATAGCGTGGGCGTTGGGCGTGCGCATTTCGAGAAGCAACCGCCTAGCAACCTGCGCAAGAGCAACTTCTTCCATTTCGTCGTAGCATTGTACGATCGCGCCGGGCAACCGGTCGAGATTGAACGGACAGCGTTCATAGGCTTCATTGAAAAGGACCAGGAGCCTGAAGGTCAGAAAACAAATAATGGCATACAATATAGACTGCAATTACTTTACGCTAATGGTATTAGACAAGAACAGGATATTTTCGTCCGTCTCATCGATTCGGTAACGAAGCAGCCGATTGTTTATGAAGGTCAAGATAAGAATCCAGAAATGTGCAGGGTTTTACTCACGCATGAGGTCATGTGCAGTCGCTGCTGTGATAAGAAAAGTTGTGGTAACAGAAACGAAACACCTTCGGATCCCGTCATCATAGACAGGTTTTTTCTCAAATTCTTCTTGAAATGCAATCAGAATTGTTTGAAGAACGCTGGCAATCCGAGAGACATGAGAAGATTTCAAGTAGTAATATCAACGCAAGTGATGGTGGACGGGCCGTTGCTAGCGATATCGGACAACATGTTTGTCCACAACAACAGCAAGCACGGCCGCAGAGCGAAAAGGCTCGATCCCACTGAAGCTGGCTTATACCCACCTTTGCCGGTCGCTACGCCGTGCATCAAGGCCATCTCGCCCAGCGAAGGCTGGACGTCAGGAGGTTCCACCGTGATTATAGTAGGAGACAACTTCTTCGACGGATTGCAAGTCGTGTTCGGAACCATGCTAGTCTGGAGTGAGTTAATAACATCACACGCGATACGAGTCCAAACACCGCCAAGACACATACCGGGGGTAGTTGAAGTGACATTATCATACAAGAGCAAGCAATTCTGTAAAGGAGCGCCCGGCAGATTTGTTTATGTTTCAGCACTCAACGAACCGACGATAGATTACGGATTCCAGAGGCTACAGAAACTTATACCGAGACATCCCGGTGACCCGGAAAAACTGCCGAAGGAAATCATTCTAAAACGAGCGGCTGACTTAGCGGAAGCATTGTATTCGATGCCAAGGAACAATCAGCTTGGATTAGGAGCGCCAAGGTCCCCTCCAGCCAGCATGCCTTTCAACTCGTATACTGGACAGTTGGCGGTTAGCGTGCAGGACACTGCGGCATCGCAGTGGACCGAAGAAGAGTACGCGCGTAGTGGCGGCTCCGTTTCGCCGCGGTATTGCTCCGCCGCGTCTACCCCGCACGCCGCGCCCGCGTCCTACCCTCATCCACAGCACTACCCCGCACCTCCCACCTCGCTATTCAATACTACCTCACGAATGGGCGGTCTCGTCTCGTCTCCGTTCAGTATGAATCCGTTTTCCTTACCGACCTGCAGTTCCCAGCAGTACGCTCAGACAGCTCCACTAGCGTCCAAGTAA

Protein

MFGLHHQEAAGGLHAQPRGPVTSLKEEPLTRAWMTPSSLVDNTNSVGVGRAHFEKQPPSNLRKSNFFHFVVALYDRAGQPVEIERTAFIGFIEKDQEPEGQKTNNGIQYRLQLLYANGIRQEQDIFVRLIDSVTKQPIVYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVISTQVMVDGPLLAISDNMFVHNNSKHGRRAKRLDPTEAGLYPPLPVATPCIKAISPSEGWTSGGSTVIIVGDNFFDGLQVVFGTMLVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFVYVSALNEPTIDYGFQRLQKLIPRHPGDPEKLPKEIILKRAADLAEALYSMPRNNQLGLGAPRSPPASMPFNSYTGQLAVSVQDTAASQWTEEEYARSGGSVSPRYCSAASTPHAAPASYPHPQHYPAPPTSLFNTTSRMGGLVSSPFSMNPFSLPTCSSQQYAQTAPLASK

Description

May act as a 'second-level regulator' of head patterning. Required for establishment of the PS(-1)/PS0 parasegmental border and formation of the intercalary segment. Required for expression of the segment polarity genes hedgehog, engrailed and wingless, and the segment-identity genes CAP and collar in the intercalary segment. Required at the onset of the gastrulation for the correct formation of the mandibular segment.

Similarity

Belongs to the COE family.

Keywords

Alternative splicing   Complete proteome   Developmental protein   DNA-binding   Metal-binding   Nucleus   Reference proteome   Transcription   Transcription regulation   Zinc   Zinc-finger  

Feature

chain  Transcription factor collier
splice variant  In isoform COL2.

Uniprot

A0A2A4JG02   A0A0K0PR08   E0VDL6   A0A146KX83   A0A139WNP7   A0A182XCC3   + More
A0A084VIH1   A0A1I8Q4M9   A0A1I8Q4P4   A0A1I8N494   A0A0R3NSL9   A0A0R3NUD5   A0A1I8Q4M1   B5E039   P56721-2   A0A1W4UJD2   A0A0J9RE29   A0A0J9U262   V5LWW0   B4NND0   B4HRP7   A0A0Q5VMG4   A0A0Q5VUK0   A0A0M4EIT4   A0A1I8Q4N0   A8DYD9   Q17FF9   B3MGM8   B4LPT7   A0A0Q9X9L5   B4J9B4   A0A0Q9XH04   A0A067RHK3   A0A0R3NM57   B4P7P4   A0A0Q9X8M1   A0A1W4UHI7   A0A0J9RCZ5   A1Z9V2   B3NQS4   A0A0L0CLM3   A0A0N8P088   A0A0Q9WFS1   B4KQX3   A0A0Q9XA73   A0A1W4U6K5   W8BPJ4   A0A1W4U6K0   E2QCN0   A0A0Q5VNJ6   P56721   A0A0Q9X453   A0A0P8XP72   A0A0Q9W488   A0A1I8N476   A0A0Q9XM78   A0A0Q9XC15   A0A0J9RCW6   A0A0Q5VMH3   A0A1W4UHL8   A0A0Q9X9S4   A0A1W4UJC7   A0A1W4U5X6   A0A1J1J8F7   Q7PN01   A0A1W4U5X2   A0A1W4UHI4   A0A1S3IJZ3   A0A2H8TNT9   A0A1S3II85   A0A1W4UHL3   A0A0J9RCR0   A0A0B4KFQ1   A0A158NYF5   A0A2S2P181   B4GAT0   A0A1S3IIX1   A0A1S3IHZ5   A0A087ZTZ4   A0A1S3IHW8   A0A2R2MRC8   A0A1S3IJY8   K7IMM1   A0A2C9JWV0   A0A151IY75   A0A151WK70   E5LP62   V4B2B1   E5LP63   A0A151IQI5   B5LVY5   A0A3B4UQR8   A0A2C9JWU2   A0A210QPZ0   K1QVZ4   A0A3B4GHI2   A0A3P8QDB6   A0A3P9CR21   A0A147AT31   A0A0P5GB35  

Pubmed

20566863    26823975    18362917    19820115    24438588    25315136    + More
15632085    17994087    8793297    10731132    12537572    12537569    10375526    10068642    10477305    22936249    12537568    12537573    12537574    16110336    17569856    17569867    17510324    24845553    17550304    26108605    24495485    12364791    21347285    20075255    15562597    21069538    23254933    18574105    28812685    22992520    25186727   

EMBL

NWSH01001511    PCG71015.1    KP641330    AKQ48972.1    DS235081    EEB11472.1    + More
GDHC01018972    JAP99656.1    KQ971312    KYB29395.1    ATLV01013356    KE524854    KFB37765.1    CM000071    KRT01941.1    KRT01942.1    EDY68923.1    X97803    AE013599    AY119102    CM002911    KMY93844.1    KMY93840.1    BT150395    AHA59285.1    CH964282    EDW85869.1    CH480816    EDW47911.1    CH954179    KQS62599.1    KQS62597.1    CP012524    ALC41067.1    ABV53800.1    CH477271    EAT45286.1    CH902619    EDV36786.1    CH940648    EDW61277.1    CH933808    KRG05147.1    CH916367    EDW01395.1    KRG05146.1    KK852468    KDR23267.1    KRT01940.1    CM000158    EDW91070.2    KRG00307.1    KMY93841.1    AAF58203.2    EDV55984.2    JRES01000319    KNC32344.1    KPU76444.1    KRF79883.1    EDW10329.2    KRG05149.1    GAMC01003455    JAC03101.1    AAM68551.2    KQS62596.1    KRG00308.1    KPU76445.1    KRF79882.1    KRG05144.1    KRG05145.1    KMY93842.1    KQS62598.1    KRG05148.1    CVRI01000074    CRL08068.1    AAAB01008966    EAA12970.5    GFXV01004000    MBW15805.1    KMY93843.1    AGB93512.1    ADTU01000623    ADTU01000624    ADTU01000625    ADTU01000626    ADTU01000627    ADTU01000628    ADTU01000629    ADTU01000630    ADTU01000631    ADTU01000632    GGMR01010546    MBY23165.1    CH479181    EDW32032.1    KQ980774    KYN13251.1    KQ983012    KYQ48273.1    HQ529596    ADQ39028.1    KB200702    ESP00422.1    AMQN01001456    HQ529597    KB302615    ADQ39029.1    ELU04107.1    KQ976779    KYN08411.1    EU915510    ACG76358.1    NEDP02002450    OWF50797.1    JH815886    EKC33090.1    GCES01004595    JAR81728.1    GDIQ01245009    JAK06716.1   

Proteomes

UP000218220    UP000009046    UP000007266    UP000076407    UP000030765    UP000095300    + More
UP000095301    UP000001819    UP000000803    UP000192221    UP000007798    UP000001292    UP000008711    UP000092553    UP000008820    UP000007801    UP000008792    UP000009192    UP000001070    UP000027135    UP000002282    UP000037069    UP000183832    UP000007062    UP000085678    UP000005205    UP000008744    UP000005203    UP000002358    UP000076420    UP000078492    UP000075809    UP000030746    UP000014760    UP000078542    UP000261420    UP000242188    UP000005408    UP000261460    UP000265100    UP000265160   

PRIDE

P56721    A1Z9V2   

Pfam

PF01833   TIG        + More
PF16422   COE1_DBD
PF16423   COE1_HLH

Interpro

IPR013783   Ig-like_fold        + More
IPR038173   COE_DBD_sf       
IPR014756   Ig_E-set       
IPR002909   IPT_dom       
IPR003523   Transcription_factor_COE       
IPR018350   Transcription_factor_COE_CS       
IPR036638   HLH_DNA-bd_sf       
IPR032200   COE_DBD       
IPR032201   COE_HLH       
IPR038006   COE_IPT       

SUPFAM

SSF81296   SSF81296       

Gene 3D

2.60.40.10     2.60.40.3180     4.10.280.10    

CDD

cd01175  IPT_COE
cd11606  COE_DBD

ProteinModelPortal

A0A2A4JG02   A0A0K0PR08   E0VDL6   A0A146KX83   A0A139WNP7   A0A182XCC3   + More
A0A084VIH1   A0A1I8Q4M9   A0A1I8Q4P4   A0A1I8N494   A0A0R3NSL9   A0A0R3NUD5   A0A1I8Q4M1   B5E039   P56721-2   A0A1W4UJD2   A0A0J9RE29   A0A0J9U262   V5LWW0   B4NND0   B4HRP7   A0A0Q5VMG4   A0A0Q5VUK0   A0A0M4EIT4   A0A1I8Q4N0   A8DYD9   Q17FF9   B3MGM8   B4LPT7   A0A0Q9X9L5   B4J9B4   A0A0Q9XH04   A0A067RHK3   A0A0R3NM57   B4P7P4   A0A0Q9X8M1   A0A1W4UHI7   A0A0J9RCZ5   A1Z9V2   B3NQS4   A0A0L0CLM3   A0A0N8P088   A0A0Q9WFS1   B4KQX3   A0A0Q9XA73   A0A1W4U6K5   W8BPJ4   A0A1W4U6K0   E2QCN0   A0A0Q5VNJ6   P56721   A0A0Q9X453   A0A0P8XP72   A0A0Q9W488   A0A1I8N476   A0A0Q9XM78   A0A0Q9XC15   A0A0J9RCW6   A0A0Q5VMH3   A0A1W4UHL8   A0A0Q9X9S4   A0A1W4UJC7   A0A1W4U5X6   A0A1J1J8F7   Q7PN01   A0A1W4U5X2   A0A1W4UHI4   A0A1S3IJZ3   A0A2H8TNT9   A0A1S3II85   A0A1W4UHL3   A0A0J9RCR0   A0A0B4KFQ1   A0A158NYF5   A0A2S2P181   B4GAT0   A0A1S3IIX1   A0A1S3IHZ5   A0A087ZTZ4   A0A1S3IHW8   A0A2R2MRC8   A0A1S3IJY8   K7IMM1   A0A2C9JWV0   A0A151IY75   A0A151WK70   E5LP62   V4B2B1   E5LP63   A0A151IQI5   B5LVY5   A0A3B4UQR8   A0A2C9JWU2   A0A210QPZ0   K1QVZ4   A0A3B4GHI2   A0A3P8QDB6   A0A3P9CR21   A0A147AT31   A0A0P5GB35  

PDB

3MLP     E-value=0,     Score=1700

KEGG

101736691    K09103 early B-cell factor | (RefSeq) transcription factor collier-like

GO

GO:0003700   GO:0007275   GO:0046872   GO:0005634   GO:0046983   GO:0003677   GO:0001228   GO:0045944   GO:0007526   GO:0035288   GO:0007367   GO:0048814   GO:0035203   GO:0010468   GO:0035287   GO:0035289   GO:0035291   GO:0007474   GO:0016204   GO:0045087   GO:0009608   GO:0007419   GO:0007350   GO:0042694   GO:0007476   GO:0048813   GO:0006355   GO:0001700   GO:0005515   GO:0006468   GO:0016075   GO:0005524   GO:0016787   GO:0004713   GO:0016491   GO:0015930  

PANTHER

PTHR10747  

Subcellular location

Nucleus  

Length:

514

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01954

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00090

outside

1  -  514

 

 

Pi

305.522747

Theta

195.989092

Tajima's D

1.602909

CLR

0.171489

CSRT

0.809359532023399

Interpretation

Uncertain