Gene

KWMTBOMO12718

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr21(+):13094376-13097633      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon X-element      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.708

CDS

ATGGTCAGGAACGACAGGCTCTCTGCCCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCGCTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGATCGTTCTAAGCAGTGATATCGAGGCGCTGCTCGGTATGGGGAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATCAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGGCTTGACGCGTTAGTCGATGATCTCGCCTTCGATATCGTCGCTCCGCTAACCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCATCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAACCCGGACTCTATCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCTTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATACGCGCCTACGACAGGTATCCTACCGCGGAAAATCGTATTCGAATGCGTGCCCTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCCTCTGATGCGTTACCACCCGTCACCCCGATGGAAGTTAAAGACTTGATCAAAGTCCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCTGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCAATTCGGAAATACATGAAGTCAGCGTCGGAACGATACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAAGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTTGCATTAGATGCCTTCAGCTCTAATACTAGGGGCAGGCTTAGGGACCCCGGTAACCGTACTCGTCGAACTCGACAAAGAGGTCGACGTGCAACCTAA

Protein

MVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTLRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFNPDSIPSPQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDDIRELLRAKNASIRAYDRYPTAENRIRMRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARTLKSDTVVTMPPLVGPSGRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRASLPPSDALPPVTPMEVKDLIKVLRPRKAPGSDGISNRVIKLLPVQLIVMLAFSMPLWRTVSFPRCGKKRTLSAYINPVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHARASHRRRPRHVLTDPSDPITFALDAFSSNTRGRLRDPGNRTRRTRQRGRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon X-element

Uniprot

Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   V5GNJ2   A0A139W8G9   + More
A0A139WA11   V5GNF3   A0A023EYS8   X1WLB2   A0A2S2QEE0   J9LC21   A0A2S2PPK8   A0A023EZE6   K7IN67   X1WQI9   A0A224XB44   J9JZG6   J9KPF1   A0A2J7QR37   A0A2J7PQB5   J9LFC9   A0A224XF24   X1WZH0   A0A2J7QY69   A0A2J7PBY3   A0A2J7PU96   A0A224X6Q4   A0A2S2Q383   A0A1Y1LKN6   A0A069DZL8   A0A0J7MYU2   J9M522   A0A2J7R7D0   J9JS95   A0A2S2PJG2   A0A2S2NGV8   J9LR29   A0A2S2N6Q7   A0A087UGF5   A0A1Y1KFR3   Q07995   A0A2J7Q6J2   A0A2S2R9D4   A0A2S2N814   A0A3N5Z7I3   J9KKL3   A0A224X6U5   A0A2J7PVX3   A0A0A9YJ00   A0A224XI99   A0A2S2NH02   A0A2J7PDM0   A0A224X746   A0A0A9YU04   A0A2J7QB68   A0A0V0G5B6   J9KSK5   A0A2M4BD67   A0A2M4BDV6   A0A352X8G4   A0A2S2PHL7   A0A2M4BD83   A0A2S2NPG3   A0A2A4K918   A0A224XIB0   A0A069DX78   A0A142LX49   A0A2J7RD70   A0A2S2PX53   A0A2S2NJB5   Q8T9X4   Q8I7P8   A0A2H8U0H5   A0A2J7R4U3   A0A2J7Q9Z1   A0A2J7PSM7   A0A0M4EWX7   Q9NBX4   A0A2J7RQ52   A0A2J7Q0S7   A0A2J7R098   A0A2J7R2E1   A0A2J7QES2   A0A2J7QFL0   A0A2J7RKP3   A0A2J7PMN4   J9LF86  

EC Number

2.7.7.49

Pubmed

26354079    10380107    28004739    18362917    19820115    25474469    + More
20075255    26334808    8387152    30086797    25401762    30148503    25527032    11405632   

EMBL

AB055391    BAB21761.1    KQ459265    KPJ02064.1    AF081103    AAC72921.1    + More
GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    ABLF02042518    ABLF02057746    GGMS01006359    MBY75562.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GGMR01018716    MBY31335.1    GBBI01004571    JAC14141.1    ABLF02022418    GFTR01008262    JAW08164.1    ABLF02037436    ABLF02041767    NEVH01011985    PNF31054.1    NEVH01022639    PNF18527.1    ABLF02023911    GFTR01008038    JAW08388.1    ABLF02034467    NEVH01009134    PNF33528.1    NEVH01027074    PNF13841.1    NEVH01021205    PNF19912.1    GFTR01008279    JAW08147.1    GGMS01002992    MBY72195.1    GEZM01053022    JAV74219.1    GBGD01000415    JAC88474.1    LBMM01013518    KMQ85605.1    ABLF02024246    NEVH01006736    PNF36716.1    ABLF02028535    ABLF02028545    GGMR01016905    MBY29524.1    GGMR01003407    MBY16026.1    ABLF02025082    ABLF02039175    ABLF02041809    GGMR01000226    MBY12845.1    KK119692    KFM76444.1    GEZM01084969    JAV60363.1    S59870    AAB26437.2    NEVH01017470    PNF24199.1    GGMS01017365    MBY86568.1    GGMR01000676    MBY13295.1    RPOV01000134    RPJ78669.1    ABLF02029306    ABLF02029314    ABLF02060138    GFTR01008251    JAW08175.1    NEVH01020940    PNF20481.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GFTR01008256    JAW08170.1    GGMR01003864    MBY16483.1    NEVH01026386    PNF14434.1    GFTR01008151    JAW08275.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    NEVH01016302    PNF25823.1    GECL01003538    JAP02586.1    ABLF02014118    ABLF02014121    ABLF02054790    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    DNOY01000259    HBE18313.1    GGMR01016296    MBY28915.1    GGFJ01001822    MBW50963.1    GGMR01006408    MBY19027.1    NWSH01000032    PCG80496.1    GFTR01008246    JAW08180.1    GBGD01000389    JAC88500.1    KU543685    AMS38375.1    NEVH01005295    PNF38784.1    GGMS01000737    MBY69940.1    GGMR01004661    MBY17280.1    AF456125    AAL57609.1    AY180919    AAN87272.1    GFXV01007093    MBW18898.1    NEVH01007402    PNF35856.1    NEVH01016340    PNF25410.1    NEVH01021925    PNF19341.1    CP012527    ALC48130.1    AF237761    AAF81411.1    NEVH01001347    PNF42959.1    NEVH01019963    PNF22185.1    NEVH01008277    PNF34262.1    NEVH01007838    PNF34986.1    NEVH01015305    PNF27092.1    NEVH01014858    PNF27387.1    NEVH01002716    PNF41415.1    NEVH01023979    PNF17579.1    ABLF02017815   

Proteomes

UP000053268    UP000007266    UP000007819    UP000002358    UP000235965    UP000036403    + More
UP000054359    UP000218220    UP000092553   

PRIDE

Q9BPQ0    Q8T9X4    Q8I7P8    Q9NBX4   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR000477   RT_dom        + More
IPR036691   Endo/exonu/phosph_ase_sf       
IPR005135   Endo/exonuclease/phosphatase       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   V5GNJ2   A0A139W8G9   + More
A0A139WA11   V5GNF3   A0A023EYS8   X1WLB2   A0A2S2QEE0   J9LC21   A0A2S2PPK8   A0A023EZE6   K7IN67   X1WQI9   A0A224XB44   J9JZG6   J9KPF1   A0A2J7QR37   A0A2J7PQB5   J9LFC9   A0A224XF24   X1WZH0   A0A2J7QY69   A0A2J7PBY3   A0A2J7PU96   A0A224X6Q4   A0A2S2Q383   A0A1Y1LKN6   A0A069DZL8   A0A0J7MYU2   J9M522   A0A2J7R7D0   J9JS95   A0A2S2PJG2   A0A2S2NGV8   J9LR29   A0A2S2N6Q7   A0A087UGF5   A0A1Y1KFR3   Q07995   A0A2J7Q6J2   A0A2S2R9D4   A0A2S2N814   A0A3N5Z7I3   J9KKL3   A0A224X6U5   A0A2J7PVX3   A0A0A9YJ00   A0A224XI99   A0A2S2NH02   A0A2J7PDM0   A0A224X746   A0A0A9YU04   A0A2J7QB68   A0A0V0G5B6   J9KSK5   A0A2M4BD67   A0A2M4BDV6   A0A352X8G4   A0A2S2PHL7   A0A2M4BD83   A0A2S2NPG3   A0A2A4K918   A0A224XIB0   A0A069DX78   A0A142LX49   A0A2J7RD70   A0A2S2PX53   A0A2S2NJB5   Q8T9X4   Q8I7P8   A0A2H8U0H5   A0A2J7R4U3   A0A2J7Q9Z1   A0A2J7PSM7   A0A0M4EWX7   Q9NBX4   A0A2J7RQ52   A0A2J7Q0S7   A0A2J7R098   A0A2J7R2E1   A0A2J7QES2   A0A2J7QFL0   A0A2J7RKP3   A0A2J7PMN4   J9LF86  

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

841

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.3774

Exp number, first 60 AAs:

0.05507

Total prob of N-in:

0.01469

outside

1  -  841

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

3.335234

CSRT

0

Interpretation

Uncertain