Gene

KWMTBOMO12700

Annotation

PREDICTED:_RNA-directed_DNA_polymerase_from_mobile_element_jockey-like_[Plutella_xylostella]

Location

Bomo_Chr21(-):12165838-12170806      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.82

CDS

ATGTCTGGGGGAAATTCACCCCCGCTCATCAGCACTCCCGGCCCGTCTCACAAGGGACGACAGGTGATGCCTCAATCAAGCAGATACCAACCAACGCCAGCAGCTCGCATAGGCTCGATGGGACTCGGGACGGACAGTCTGCCCGGGCCTTCGGTCGCGGCCCAGAGGACTCTGAGGATCGAACCGGAGGAAGATAACCTTCCTTCGTTGACCGATCCCTCTGGGCCCTCTCGGCCGCGGAAGAAGGCCAGGTCCGAGTCTGACCGAGGCTCATCGAGCGATAAGGACAAGCGTCCCAGACTAGGCCCTTCCTCCAGATCGGAGGGGGAGGATAGTTCGACCACGTCCTCGGCTCATTCCTCGACAGAATCAGTCACTCCCTCCTCGTCCAGATCTTCGTCCCCCTCTGGGAGTCCAATCCCAGCTAAACCAACTCCGAAACCTAGGGCTCCCACCAGGACAGGGATAGCCCTAAGGCAACAACGATCCCCTCCTCGTTCTCCCTCCCCAACGCTTTCCCCTATCCCGGTAGACTCAACCCGAGGTGCCCCCGCCCTAAGCGGCACGGCGGGTAACCTGGATTCGACCAGGTATATGGACCTCGAGTCTACCAGACCACACGTCCCAAAGCCCAATCCCACTCCTTCTACCTCCTATGCTGCCATGGCAGCTAGGCCAGGTGTTCCCACCACCCAGAGGACTTCCCAATCCTCACAAATTCCTCCCCCGAGGCCGAAGGGTCGTGCCCAGGAGGCCTACCTGTCGGAGGCCTCTGCCAGGGACAGTGCCATTAAATGGTACTGTTACGCCCTGGCGGAGGAGATGCCTTCGAAGGTGGCGGTCCGGGGCCTCCCTGCCGACACCGACGAGGCAGAAATCGTCAATGCCCTGAAGGAGCTGGGATTCCCGGCTCGATATGCCAGGTGCATTAGGTCCCAGAGAGGGCGTCCGGGCTGCGTGTTTCACGTAGCCCTGGATCACCTCTCGAAGGACGGTCTCGCCCGCTTGTACGCAGTCAACGAACTGCTGTACCTGCCGGGGGTGACGGTGGAAGGATGGCGTCCAACCCGAGGACCTGCGCAGTGTCATCGCTGCCAGGGCTTCGGACACGCCTCCTACAACTGTCATCGTGCGGTCCGTTGCGTAAGCCAGGAGCTTCGCATCATCTATTGGAACCCCGATGGGATAAGATCCCGAAAAAACGATCTCTTGGTTCTCGCCCAGGAGTACAACCCTGAGGTTCTGCTGCTGGGGGAGACCTTGTTAAAACCTCAGGATGTGTTCAGGATTCCCAACTATTTCATGTACCGACGTGACGAGCTTACCCCTGCCGGGCGGCCGTTCAGGGGCACTGCGGCCCTTGTCAGGCGGGACGTGGTGCATGATCAGTTGGATTTGCTGTCCTTCACATCGACAAGACCCCCGGGGCCTGAATTCCATCCTGAGGATATAAGACGGGCCCTGAATTACGACAGCCGCCCAGCTCTGCTGGTCGGGGACCTCAACGCGAAGCACGTCGCGTGGGGTTCCCGACTTAACACAGCAGTGGGCAGGCGGCTGTTAGAAGATGCCGATAGGGGCGACTACTCTGTGGTCGGCCCTGATGAACCCACGCACGTCCCGACCGCCGCGCGATACCAGCCCGATGTGCTGGACGTGTGTGTTCATAAGGGGCTACGGTGCCCCGTAACGATCGAGGCACTGTACGACCTGGGTACCCCACATCTCCCTGTCCTGGTGACACTGGGAATGGGGCTCACCCGGGTTGCGACTTCGCCCCTACGACCGAAGGTCGACTGGGAGCTCTTTAAGAGACGACTAGTCGACCTTCCCGTAATTCAGGACCCCAACACCCCTGAGGGGGTCGATGACGCGGCAGTCCGCCTTATCGACTCCATCAGGGGAGCGATTGACCAGGCGACGACTCTTGTGCCCAGCGGCGGGCCCAGAGGTAGACTCCCGGCCCATCTGAAGGCGATCATTCGCCGGAAGAGGGGCCTGAGGAGGCTCTGGGCGACAACTCGTTGTCCCAGGATCAAGCGCGAGCTTAATGAGTTGGAAGCGGAGTTGGCGGCGAAGATTAGCTCCTTTCGGGGCTATGCGTGGGAGGAACGGATTGAGGAGGCCCGTGAGGACCCCTCTTCCGTGTCCCTCCACCGACTTTGCCGCCAGCTCTCAAATCGGCCTGCCCCGACTTGTCCACTCGTGGACGAGAGGGGCAACCGATGCTTCTCGGCTCAGGCCCGCGCCGATGTCCTGGCCGCAATGCTGGAGCGGCAGTTCGTTCCGAATGACTCTGCACCCTCAGAGGCCGCATTCCACCAATCGGTGGAAGAGAGCGTAGCGAACCTACTCTCCTCCCCGGTGCCACCGTTGGGAGATGATGTTTTCATCACTCCCAGTGAATTGCGCCTCTCCATCAAGCGGATGAAGAGGCGCAAGGCGCCGGGTGAGGACGGTATTCCCTCCCTCGCATTCTTCCACTTCCCTGAAACGGTCGTGTCATACATGACACGGCTGTTCAATTCCATTCTGTCCACAGGACACTTCCCGGGAATTTGGAAATTGGGCAAGGTTATCGCCTTGCCCAAACCCGGCAAGGATAGGAGAAATCCCTCCAGTTACCGTCCGATCACCTTGCTGTCGCATGTGGGCAAGTTGTTCGAGAGGCTGCTGCTGAGAAGGGTGTCGCCGCACATCCTTCCCAGACCCGAGCAGTTCGGGTTTCGCAGCGGTCACTCGACAACGCTGCAATTGGTCCGCGTCATGCATCACTTGGCGGATCGGTCCAACGCGCGCCAGTACACGGCCGCAGTCTTTCTCGATATCGAGAAAGCCTTCGACCGTGTCTGGCATGCGGGACTGATCCACAAGCTGGTGCAGAACACGGACCTCCAGCACGCCTACGTGCGACTGCTGGGGTCGTACCTGGAGGGAAGATCCTTCTTTGTCGCGGTCGAGGGCGCCAAGTCGTCGGTGCGCCCAGTCACGGCCGGAGTTCCGCAGGGAAGCGTCCTGGCCCCACTCCTCTACGCTCTCTACACAAACGACATTCCCACGCTCGAGGGTAACCTCCAAGCGTGGGAAGTAGACGTGAAGTTGGCGCTGTTTGCCGACGACAGCGCCTACTTCTCGTCATCCAACGTCCCCTCTGCGGCCATTTTGAGGATGCAGAGGCTTTTGGACCTACTGCCCCAGTGGCTGGACCGATGGAGGGTCGCGGTCAACGTGGGGAAGACTGCGGCTATCCTCTTCGGTCCGGTCCGCACAACAGTCGTCCCGGGACAGCTCAGTCTCCGTGGCGCTAATGTCGAGTTTAGATCCAGCGTCCGGTACTTGGGGGTCGATATCGACCGGAGTTTGAGGATGACCGCCCACGCCAATAAGGCGTTGGCGGCCGCTCGCTGTGCGAGATTCCTCCTCCGGCCGGTGTTGGCCTCCAGGTTGCCGGTCAGGACTAAGCTCGGCATTTATAAGACGTATGTCCGTTCCCGTATCACGTACGCAGCTGAGGCCTGGTATCACCTCATCCCGCAGGGTATGCGGGCGAGGTTACAGGTCCAGCAAAATCTGGCTCTTCGCACGATAGTCGGAGCAGGGCGTTACGTCAGAAATGACGTAATCGCCCGGGATCTAGATGTGGAGTCGCTCGAGGAGTTCATCCGGAGGCTAGCTCGTAATCTTTACGAGCGGGCTGACGGTGGACCCCACGAGCACCTCCACAATATAGCTCCCTTGCACGCCAGACCACCTGATGGTCGGGCGCTACCAAGGGAGCTACTGGAACCCCCGGCTATGGTAAGATAG

Protein

MSGGNSPPLISTPGPSHKGRQVMPQSSRYQPTPAARIGSMGLGTDSLPGPSVAAQRTLRIEPEEDNLPSLTDPSGPSRPRKKARSESDRGSSSDKDKRPRLGPSSRSEGEDSSTTSSAHSSTESVTPSSSRSSSPSGSPIPAKPTPKPRAPTRTGIALRQQRSPPRSPSPTLSPIPVDSTRGAPALSGTAGNLDSTRYMDLESTRPHVPKPNPTPSTSYAAMAARPGVPTTQRTSQSSQIPPPRPKGRAQEAYLSEASARDSAIKWYCYALAEEMPSKVAVRGLPADTDEAEIVNALKELGFPARYARCIRSQRGRPGCVFHVALDHLSKDGLARLYAVNELLYLPGVTVEGWRPTRGPAQCHRCQGFGHASYNCHRAVRCVSQELRIIYWNPDGIRSRKNDLLVLAQEYNPEVLLLGETLLKPQDVFRIPNYFMYRRDELTPAGRPFRGTAALVRRDVVHDQLDLLSFTSTRPPGPEFHPEDIRRALNYDSRPALLVGDLNAKHVAWGSRLNTAVGRRLLEDADRGDYSVVGPDEPTHVPTAARYQPDVLDVCVHKGLRCPVTIEALYDLGTPHLPVLVTLGMGLTRVATSPLRPKVDWELFKRRLVDLPVIQDPNTPEGVDDAAVRLIDSIRGAIDQATTLVPSGGPRGRLPAHLKAIIRRKRGLRRLWATTRCPRIKRELNELEAELAAKISSFRGYAWEERIEEAREDPSSVSLHRLCRQLSNRPAPTCPLVDERGNRCFSAQARADVLAAMLERQFVPNDSAPSEAAFHQSVEESVANLLSSPVPPLGDDVFITPSELRLSIKRMKRRKAPGEDGIPSLAFFHFPETVVSYMTRLFNSILSTGHFPGIWKLGKVIALPKPGKDRRNPSSYRPITLLSHVGKLFERLLLRRVSPHILPRPEQFGFRSGHSTTLQLVRVMHHLADRSNARQYTAAVFLDIEKAFDRVWHAGLIHKLVQNTDLQHAYVRLLGSYLEGRSFFVAVEGAKSSVRPVTAGVPQGSVLAPLLYALYTNDIPTLEGNLQAWEVDVKLALFADDSAYFSSSNVPSAAILRMQRLLDLLPQWLDRWRVAVNVGKTAAILFGPVRTTVVPGQLSLRGANVEFRSSVRYLGVDIDRSLRMTAHANKALAAARCARFLLRPVLASRLPVRTKLGIYKTYVRSRITYAAEAWYHLIPQGMRARLQVQQNLALRTIVGAGRYVRNDVIARDLDVESLEEFIRRLARNLYERADGGPHEHLHNIAPLHARPPDGRALPRELLEPPAMVR

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

X1WLB2   X1WZH0   J9LC21   A0A2J7PBY3   A0A2J7QY69   A0A2J7QR37   + More
A0A2J7PU96   A0A224X6Q4   A0A087UCW3   A0A2J7Q6J2   J9LF85   A0A2J7R4U3   V5GNF3   A0A0A9YJ00   A0A2J7QB68   A0A0A9YU04   A0A2J7R7D0   A0A2H8TF37   A0A2J7PVX3   A0A2S2NGV8   A0A2M4CV52   A0A2S2Q383   A0A224XJI0   A0A224XIB0   A0A023F0I3   A0A224X6T4   Q9BPQ0   A0A1Y1KFR3   A0A069DX78   A0A2M4CV42   Q9XXW0   O96546   A0A224X6U5   A0A023F069   A0A2S2NPG3   A0A224X6R6   P21328   A0A2S2QEE0   A0A2S2N814   A0A087UGF5   Q93137   A0A2S2PHL7  

EC Number

2.7.7.49

Pubmed

25401762    25474469    28004739    26334808    10333566    10380107    + More
2463954    3040362    1714378   

EMBL

ABLF02042518    ABLF02057746    ABLF02034467    ABLF02036316    ABLF02036319    ABLF02048663    + More
ABLF02066977    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    NEVH01011985    PNF31054.1    NEVH01021205    PNF19912.1    GFTR01008279    JAW08147.1    KK119261    KFM75202.1    NEVH01017470    PNF24199.1    ABLF02017813    NEVH01007402    PNF35856.1    GALX01005359    JAB63107.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    NEVH01016302    PNF25823.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    NEVH01006736    PNF36716.1    GFXV01000908    MBW12713.1    NEVH01020940    PNF20481.1    GGMR01003407    MBY16026.1    GGFL01004957    MBW69135.1    GGMS01002992    MBY72195.1    GFTR01008257    JAW08169.1    GFTR01008246    JAW08180.1    GBBI01003747    JAC14965.1    GFTR01008261    JAW08165.1    AB055391    BAB21761.1    GEZM01084969    JAV60363.1    GBGD01000389    JAC88500.1    GGFL01005012    MBW69190.1    AB018558    BAA76304.1    AF081103    AAC72921.1    GFTR01008251    JAW08175.1    GBBI01003810    JAC14902.1    GGMR01006408    MBY19027.1    GFTR01008269    JAW08157.1    M22874    M38643    GGMS01006359    MBY75562.1    GGMR01000676    MBY13295.1    KK119692    KFM76444.1    U07847    AAA17752.1    GGMR01016296    MBY28915.1   

Proteomes

UP000007819    UP000235965    UP000054359   

PRIDE

Q9BPQ0    Q9XXW0    P21328    Q93137   

Pfam

PF00078   RVT_1        + More
PF07530   PRE_C2HC
PF14529   Exo_endo_phos_2
PF07727   RVT_2
PF03372   Exo_endo_phos

Interpro

IPR000477   RT_dom        + More
IPR006579   Pre_C2HC_dom       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR005135   Endo/exonuclease/phosphatase       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

X1WLB2   X1WZH0   J9LC21   A0A2J7PBY3   A0A2J7QY69   A0A2J7QR37   + More
A0A2J7PU96   A0A224X6Q4   A0A087UCW3   A0A2J7Q6J2   J9LF85   A0A2J7R4U3   V5GNF3   A0A0A9YJ00   A0A2J7QB68   A0A0A9YU04   A0A2J7R7D0   A0A2H8TF37   A0A2J7PVX3   A0A2S2NGV8   A0A2M4CV52   A0A2S2Q383   A0A224XJI0   A0A224XIB0   A0A023F0I3   A0A224X6T4   Q9BPQ0   A0A1Y1KFR3   A0A069DX78   A0A2M4CV42   Q9XXW0   O96546   A0A224X6U5   A0A023F069   A0A2S2NPG3   A0A224X6R6   P21328   A0A2S2QEE0   A0A2S2N814   A0A087UGF5   Q93137   A0A2S2PHL7  

PDB

6AR3     E-value=2.8429e-05,     Score=118

KEGG

101740860    no KO assigned | (RefSeq) putative uncharacterized protein DDB_G0290521

GO

GO:0003964   GO:0004519  

Length:

1268

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00366

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00000

outside

1  -  1268

 

 

Pi

5.102859

Theta

5.121119

Tajima's D

-1.248383

CLR

5.821569

CSRT

0.0893455327233638

Interpretation

Uncertain