Gene

KWMTBOMO11408

Pre Gene Modal

BGIBMGA001947

Annotation

hepatocyte_nuclear_factor_4_isoform_a_[Bombyx_mori]

Location

Bomo_Chr19(-):4889429-4923125      View in EpiBrowser

Transcription factor

RXR-like

Location in the cell

Nuclear   Reliability : 3.752

CDS

ATGGGATACAGTGCTGCGTCGGAGTACATGGTCCCGGCCCACGTGTGGGAGAAGCAGCACAACGCTCCCTACAGCGACTTCCAGTCCAGAAGCGGAGGAGCAGACCACCGCGGGATCAACGTGACATACAACAGCGAAGATAGTGATATGCAGCTGGAGACGAGCAGTAGCGAGGCAAGCGCAGCCAGTTCCACGACCATATCCCAGCATTGCGCCATCTGCGGGGACAGGGCGACGGGCAAGCATTACGGTGCCTCGTCCTGTGACGGATGCAAAGGATTCTTCAGACGGAGCGTGAGGAAGAACCATTTGTATACATGCCGTTTCAGCAGGAACTGTGTAGTCGACAAAGACAAAAGGAACCAATGCAGATATTGTAGATTAAGGAAGTGCTTCAAAGCCGGCATGAAAAAAGAAGCTGTTCAAAACGAAAGGGACAGGATCAACTGCAGGCGACCTTCTTACGAAGAACCGACGCAGGCCAACGGTCTATCTGTTGTATCGCTCCTCAACGCTGAACTCCTGAGTAGAAAAGTCATTGACGAGACTGTAAACGTGAGCGACGCCGAAATAAACAATAGGAAGCTAGCAAAGATCAACGATGTATGCGATTCGATAAAACAGCAACTACTCATATTGGTGGAGTGGGCTAAATACATACCCGCCTTCACGGAGCTACACCTCGACGATCAGGTGGCGTTGCTGCGTGCTCACGCCGGCGAGCACCTGCTGCTGGGCTGCGCGCGTCGCTCGCTGCACCTCAAGGACATACTGCTGCTCGGGAACAACTGCATCATCACGAAGCACAACATCGATGGTCGTATGGACATTGACATTAGCATGATAGGCATGCGCGTCATGGACGAGATAGTGAAGCCGCTGCGAGAGATTGACATAGACGACACTGAATTCGCATGTTTGAAAGCTATCGTCTTCTTCGATCCAAACGCGAAAGGCCTGTCCCAGCCGCAGAAGATCAAGCAGCTCCGCTACCAGATCCAGATCAACCTGGAGGACTACATAAGCGACCGGCAGTACGACGGGCGCGGGCGGTTCGGGGAGCTGCTGCTGTGCCTGCCGCCGCTGCAGAGCATCACGTGGCAGATGATCGAGCAGATCCAGTTCGCGAAGCTGTTCGGGGTCGCGCACGTCGACAGCCTGCTGCAGGAGATGCTGCTCGGCGGGGCCACAACAGAAGCCGTCCTGGAGGAGCCGTCCCCGGAGCCGGCGGCCGCATCCCCCTCTCCGCCGCTAGTGCCGCTGGTGCCGCTAGTGCCGCAACTGCCGCAGCTGCCGGGCAACGACTCCGCCTTCCTCGAACCGATGCCCTTCAAACAAGAGCCCAACATCTAA

Protein

MGYSAASEYMVPAHVWEKQHNAPYSDFQSRSGGADHRGINVTYNSEDSDMQLETSSSEASAASSTTISQHCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHLYTCRFSRNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRINCRRPSYEEPTQANGLSVVSLLNAELLSRKVIDETVNVSDAEINNRKLAKINDVCDSIKQQLLILVEWAKYIPAFTELHLDDQVALLRAHAGEHLLLGCARRSLHLKDILLLGNNCIITKHNIDGRMDIDISMIGMRVMDEIVKPLREIDIDDTEFACLKAIVFFDPNAKGLSQPQKIKQLRYQIQINLEDYISDRQYDGRGRFGELLLCLPPLQSITWQMIEQIQFAKLFGVAHVDSLLQEMLLGGATTEAVLEEPSPEPAAASPSPPLVPLVPLVPQLPQLPGNDSAFLEPMPFKQEPNI

Similarity

Belongs to the nuclear hormone receptor family.

Uniprot

O46174   O46175   A0A2A4K916   A0A2H1WEA5   A0A0N0PBY4   A0A194QKI6   + More
A0A212FLQ4   Q1KTF4   A0A139WFC1   A0A139WF19   A0A1W4XIN3   A0A1W4XJT8   A0A1Y1LA96   A0A1W4XJL9   A0A139WFB8   D6WSJ2   A0A139WF08   A0A1W4X957   A0A1Y1L865   A0A1Y1LDZ1   A0A1W4X9E0   A0A139WFI4   A0A1W4XJL4   A0A1W4XIM7   A0A1W4XJM4   A0A1W4X958   A0A1Y1LA81   A0A1W4X9E4   A0A1W4XJU3   A0A1Y1LCW4   A0A1Y1LFK4   A0A1B6KBL3   A0A1B6MHM9   A0A0L7R0C5   A0A1B6L3F7   A0A1B6L270   D2CPV5   V5I8N9   A0A1S5UZQ1   V5G277   A0A0C9QBL7   A0A220XK81   A0A0C9S015   A0A0C9QH11   E0VWC2   A0A2J7PI01   A0A2J7PI19   A0A0C9RET9   N6U7V6   A0A3L8DB82   A0A026WYG3   A0A1B6IFT4   A0A1B6JAB7   A0A1B6F1Q5   A0A1B6JYX0   A0A1B6J3C8   A0A1B6H8Y4   A0A1B6GL07   A0A1B6CX94   W8B9A5   A0A067R1M5   A0A336M736   W8B4X7   A0A1I8MY45   A0A023F9Y2   A0A161MBV2   A0A0M8ZMX6   A0A0K8U345   A0A0A1WXP8   A0A0N7Z8N9   A0A0A1WML3   A0A2S2PY23   R4G2Q8   A0A034V6Y7   A0A034V9N9   A0A224XDE1   A0A1I8Q8F5   A0A1S3J4P6   A0A2T7NHA4   R4WQQ0   E2C293   A0A1B0B7J3   A0A1A9Y0L9   A0A1B0A4U8   A0A1S3J5Z2   A0A0L0CLU4   A0A1A9VZY8   J9K904   A0A2H8TTW3   A0A1S3J4E3   A0A1S3J492   A0A2S2NTE3   A0A0P5C3B8   A0A1A9V759   A0A0P5PDR9   A0A0P5CDB8   K1QT78   A0A1S3J5Y7   E9H7Y7   T1HVZ2  

Pubmed

26354079    22118469    18362917    19820115    28004739    20048156    + More
20566863    23537049    30249741    24508170    24495485    24845553    25315136    25474469    25830018    27129103    25348373    23691247    20798317    26108605    22992520    21292972   

EMBL

U63843    AAB93762.1    U63844    AAB93763.1    NWSH01000016    PCG80775.1    + More
ODYU01008094    SOQ51399.1    KQ460772    KPJ12471.1    KQ459053    KPJ03971.1    AGBW02007717    OWR54675.1    DQ427106    ABD85142.1    KQ971354    KYB26571.1    KYB26570.1    GEZM01062353    JAV69791.1    KYB26569.1    EFA07427.1    KYB26568.1    GEZM01062359    JAV69784.1    GEZM01062357    JAV69786.1    KYB26567.1    GEZM01062355    JAV69788.1    GEZM01062358    JAV69785.1    GEZM01062356    JAV69787.1    GEBQ01031138    JAT08839.1    GEBQ01004592    JAT35385.1    KQ414670    KOC64297.1    GEBQ01021728    JAT18249.1    GEBQ01022180    JAT17797.1    EU545256    ACD77184.1    GALX01004355    JAB64111.1    KX373871    AQN67830.1    GALX01004356    JAB64110.1    GBYB01011803    JAG81570.1    KX431886    ASL05632.1    GBYB01015115    JAG84882.1    GBYB01013928    JAG83695.1    DS235818    EEB17678.1    NEVH01025130    PNF15967.1    PNF15968.1    GBYB01015114    JAG84881.1    APGK01036196    KB740937    KB632052    ENN77755.1    ERL88333.1    QOIP01000010    RLU17373.1    KK107079    EZA60149.1    GECU01021914    JAS85792.1    GECU01011607    JAS96099.1    GECZ01025580    JAS44189.1    GECU01003593    JAT04114.1    GECU01014022    JAS93684.1    GECU01036612    JAS71094.1    GECZ01006671    JAS63098.1    GEDC01019182    JAS18116.1    GAMC01012924    GAMC01012922    JAB93633.1    KK852779    KDR16688.1    UFQT01000481    SSX24689.1    GAMC01012923    JAB93632.1    GBBI01000903    JAC17809.1    GEMB01001723    JAS01441.1    KQ436240    KOX67337.1    GDHF01031403    JAI20911.1    GBXI01010871    GBXI01010570    JAD03421.1    JAD03722.1    GDKW01002819    JAI53776.1    GBXI01014552    JAC99739.1    GGMS01001242    MBY70445.1    GAHY01002391    JAA75119.1    GAKP01020693    JAC38259.1    GAKP01020694    JAC38258.1    GFTR01005989    JAW10437.1    PZQS01000012    PVD20522.1    AK418006    BAN21221.1    GL452091    EFN77940.1    JXJN01009677    JRES01000198    KNC33338.1    ABLF02034530    ABLF02034534    GFXV01005871    MBW17676.1    GGMR01007683    MBY20302.1    GDIP01176283    JAJ47119.1    GDIQ01130086    JAL21640.1    GDIP01171893    JAJ51509.1    JH818091    EKC36868.1    GL732602    EFX72163.1    ACPB03019739   

Proteomes

UP000218220    UP000053240    UP000053268    UP000007151    UP000007266    UP000192223    + More
UP000053825    UP000009046    UP000235965    UP000019118    UP000030742    UP000279307    UP000053097    UP000027135    UP000095301    UP000053105    UP000095300    UP000085678    UP000245119    UP000008237    UP000092460    UP000092443    UP000092445    UP000037069    UP000091820    UP000007819    UP000078200    UP000005408    UP000000305    UP000015103   

PRIDE

O46174    O46175   

Pfam

PF00105   zf-C4        + More
PF00104   Hormone_recep

Interpro

IPR001628   Znf_hrmn_rcpt        + More
IPR000536   Nucl_hrmn_rcpt_lig-bd       
IPR000003   Retinoid-X_rcpt/HNF4       
IPR013088   Znf_NHR/GATA       
IPR001723   Nuclear_hrmn_rcpt       
IPR035500   NHR-like_dom_sf       

SUPFAM

SSF48508   SSF48508       

Gene 3D

1.10.565.10     3.30.50.10    

ProteinModelPortal

O46174   O46175   A0A2A4K916   A0A2H1WEA5   A0A0N0PBY4   A0A194QKI6   + More
A0A212FLQ4   Q1KTF4   A0A139WFC1   A0A139WF19   A0A1W4XIN3   A0A1W4XJT8   A0A1Y1LA96   A0A1W4XJL9   A0A139WFB8   D6WSJ2   A0A139WF08   A0A1W4X957   A0A1Y1L865   A0A1Y1LDZ1   A0A1W4X9E0   A0A139WFI4   A0A1W4XJL4   A0A1W4XIM7   A0A1W4XJM4   A0A1W4X958   A0A1Y1LA81   A0A1W4X9E4   A0A1W4XJU3   A0A1Y1LCW4   A0A1Y1LFK4   A0A1B6KBL3   A0A1B6MHM9   A0A0L7R0C5   A0A1B6L3F7   A0A1B6L270   D2CPV5   V5I8N9   A0A1S5UZQ1   V5G277   A0A0C9QBL7   A0A220XK81   A0A0C9S015   A0A0C9QH11   E0VWC2   A0A2J7PI01   A0A2J7PI19   A0A0C9RET9   N6U7V6   A0A3L8DB82   A0A026WYG3   A0A1B6IFT4   A0A1B6JAB7   A0A1B6F1Q5   A0A1B6JYX0   A0A1B6J3C8   A0A1B6H8Y4   A0A1B6GL07   A0A1B6CX94   W8B9A5   A0A067R1M5   A0A336M736   W8B4X7   A0A1I8MY45   A0A023F9Y2   A0A161MBV2   A0A0M8ZMX6   A0A0K8U345   A0A0A1WXP8   A0A0N7Z8N9   A0A0A1WML3   A0A2S2PY23   R4G2Q8   A0A034V6Y7   A0A034V9N9   A0A224XDE1   A0A1I8Q8F5   A0A1S3J4P6   A0A2T7NHA4   R4WQQ0   E2C293   A0A1B0B7J3   A0A1A9Y0L9   A0A1B0A4U8   A0A1S3J5Z2   A0A0L0CLU4   A0A1A9VZY8   J9K904   A0A2H8TTW3   A0A1S3J4E3   A0A1S3J492   A0A2S2NTE3   A0A0P5C3B8   A0A1A9V759   A0A0P5PDR9   A0A0P5CDB8   K1QT78   A0A1S3J5Y7   E9H7Y7   T1HVZ2  

PDB

4IQR     E-value=3.7204e-129,     Score=1182

KEGG

693036    K08704 hepatocyte nuclear factor 4 | (RefSeq) Hnf-4; hepatocyte nuclear factor 4

GO

GO:0005634   GO:0003707   GO:0043565   GO:0008270   GO:0003700   GO:0046872   GO:0003677   GO:0016021   GO:0070365   GO:0055088   GO:0050796   GO:0003323   GO:0006355   GO:0043401   GO:0006418   GO:0003824  

Subcellular location

Nucleus  

Length:

450

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00158

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00420

outside

1  -  450

 

 

Pi

227.279096

Theta

159.310829

Tajima's D

1.264039

CLR

0.363626

CSRT

0.731813409329534

Interpretation

Uncertain