Gene

KWMTBOMO08726

Pre Gene Modal

BGIBMGA007914

Annotation

PREDICTED:_nuclear_hormone_receptor_FTZ-F1_beta_[Bombyx_mori]

Location

Bomo_Chr15(-):3547026-3567464      View in EpiBrowser

Full name

Nuclear hormone receptor FTZ-F1 beta      

Alternative Name

Nuclear hormone receptor HR39
Nuclear receptor subfamily 5 group B member 1

Transcription factor

SF-like

Location in the cell

Nuclear   Reliability : 4.561

CDS

ATGTCCAGTGAGGGTAACGCCGTGAAGGTGGAAGGTGGGCACGTTTCTGTCACCACTATCAGCATGTCCGGCCCGGAGACCAGCAATGGCCCATTCTCGTACAGTTCGAGCGGAGTACGAATCAGCGTCTCTTCGGAACCACACGACGAAGACTCGACTGATGCGGAAATCTCCAAAATCGATTTCACTCAACATCAATACGAGGTGAACATGCGAAGCAAGAAACAGCGCTCGTCGAGCGGGACCCAACGTGACAGTCTCCACGATCGGGAGCGACCCATGTCCTGGGAGGGAGAGCTGTCCGACTCCGAGATGGTCATCGATACAAGCGTCAATAACGACGAGAATAGCAATTCGTTGGACCTTCAATCGTCAAGGGATTCCATTGATACGCTCCGCAACGTGACCATTAAGGCTGAACCACTGAAGAACGAGTGCTTCCAGAGTCGTGACGATCAGCGCGTGTTGGACCTCAAGTATACGGCACCTCTGCAGCCCCACCAGAGGAGTCTCAGTATGAATAGGATATCAGTACTGACAGACAACGCGTCTCTTTCGCTTGCACGACGTCCGTCTTCACCGACCAACAGCGCCAAGTCTCTAGCGCTGTCCGACCAGGGCACAATGCCCGTAATGGCGCAGACTTCCATAGGGGAAGTCCAGAATTTGACCATCAAGAAGGAAATTCTAACAGATTTGAAATGCGAGCCCTCAGTGGGTATAGATAAGCTGATGGGCTCGCTTCACGGGTCTCCATTATTGGGTCGGCTGCCTCGCGTCCAGTCGAGCGCAAGTACAGACTCCGCTGTGCATTCCATGTATACGCATAGCGTATACAGCAGTCCTTCAGCGAGTCCGAGAGCGTCTCGACATTACACGCCGTCTCTTTCCCGCAACAACAGCGACGCATCGCACTCTTCTTGTTACTCCTATAGCTCCGAGTTCTCGCCCACACAGTCTCCAGTGCAGGGTCGACATCCGCATGTGATGTATCGCGAACCGGCCGGTGTTCTGTCGCCCGCACACGACGACGACACCGAGCCGACTGACGACAGACTCCATCATCACCAGGGTATCAGCAGACAACAGCTGATTAACAGCCCGTGCCCAATCTGCGGCGACAAAATAAGCGGCTTCCACTACGGAATCTTCTCGTGTGAATCCTGCAAGGGCTTCTTCAAGCGGACCGTACAGAATCGGAAGAACTACATGTGTCTGCGCGGCGGCAACTGTCCGGTCACCGTCGCGACCAGGAAGAAGTGTCCCGCGTGCCGGTTCGACAAGTGCCTCGGCTGCGGAATGAAGTTGGAAGCAATACGAGAGGATCGGACGAGGGGTGGAAGATCGACGTATCAGTGTTCGTATCCGCTGTCGGGCGCGGCCTCAACGGGCTCGCTGCTGTCCGCGCACGTGTCCCCCACGCTGAGGCACGCCACCAGCCTCAACTGCGTCAACGGTCCTGGATCATACAGTCGAGGAGAGTCCAGCAACAGCCGAGTGACGCCCGACATTCCACCTTTACTACAGGAAATAATGGATGTGGAACACTTGTGGCAATACAACGAATCCGAACTGAACCGGCTCGGTAGTTCGCCGGGGAGCCCCTCCGCGAACCCCCTACTCGCGGCGAGCGGCATCACCGCGCAGAATTCGAACCCGGACTTTTTAGCCGATCTATGCAACATAGCCGACCACAGATTATACAAAATCGTGAAATGGTGCAAGAGTTTACCGCTTTTCAAGAACATTTCGGTGAGTTTTGAGTCCGTGATACCCGATAATGTACTCTGTACTCTTTCAGCTGAGAAGTACTCCTGCTTATCAGTTTGA

Protein

MSSEGNAVKVEGGHVSVTTISMSGPETSNGPFSYSSSGVRISVSSEPHDEDSTDAEISKIDFTQHQYEVNMRSKKQRSSSGTQRDSLHDRERPMSWEGELSDSEMVIDTSVNNDENSNSLDLQSSRDSIDTLRNVTIKAEPLKNECFQSRDDQRVLDLKYTAPLQPHQRSLSMNRISVLTDNASLSLARRPSSPTNSAKSLALSDQGTMPVMAQTSIGEVQNLTIKKEILTDLKCEPSVGIDKLMGSLHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTQSPVQGRHPHVMYREPAGVLSPAHDDDTEPTDDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYPLSGAASTGSLLSAHVSPTLRHATSLNCVNGPGSYSRGESSNSRVTPDIPPLLQEIMDVEHLWQYNESELNRLGSSPGSPSANPLLAASGITAQNSNPDFLADLCNIADHRLYKIVKWCKSLPLFKNISVSFESVIPDNVLCTLSAEKYSCLSV

Description

Acts as a cofactor to fushi tarazu (ftz). Facilitates the binding of ftz to DNA. Binds the sequence element 5'-YCYYGGYCR-3' in the zebra element of ftz. Probably also functions as a receptor for a yet unknown ligand.

Subunit

Monomer; forms a complex with ftz.

Similarity

Belongs to the nuclear hormone receptor family.
Belongs to the nuclear hormone receptor family. NR5 subfamily.

Keywords

Activator   Alternative splicing   Complete proteome   DNA-binding   Metal-binding   Nucleus   Phosphoprotein   Receptor   Reference proteome   Transcription   Transcription regulation   Zinc   Zinc-finger  

Feature

chain  Nuclear hormone receptor FTZ-F1 beta
splice variant  In isoform C.

Uniprot

H9JEG7   A0A3S2LGD2   A0A2W1BQP5   A0A2A4K6H4   A0A212F644   A0A194PQ55   + More
O96041   A0A2H1WRM2   A0A0T6B6T1   D2A6H1   A0A1B0CHS9   U5EYK1   A0A1Y1L3R0   A0A1W4WWF8   A0A336K8C1   A0A1J1I9C9   A0A1B0DH33   B3MMC7   B4N7P4   B4IFM9   B4Q4C8   B4M9I6   B3NKS4   A0A1W4VAN9   Q05192-2   B4P6X5   Q05192   B4JC74   B4KH03   A0A1L8DN23   A0A1A9Z5M7   A0A182GKK1   A0A182GLJ0   Q17LN1   A0A1S4EYC9   Q7QGB9  

Pubmed

19121390    28756777    22118469    26354079    18362917    19820115    + More
28004739    17994087    22936249    18057021    8382937    8479913    10731132    12537572    12537569    8164672    18327897    17550304    26483478    17510324    12364791   

EMBL

BABH01003065    BABH01003066    RSAL01000014    RVE53238.1    KZ150012    PZC75060.1    + More
NWSH01000128    PCG79272.1    AGBW02010081    OWR49194.1    KQ459596    KPI95447.1    AB005660    BAA34123.1    ODYU01010523    SOQ55688.1    LJIG01009579    KRT82797.1    KQ971348    EFA05671.1    AJWK01012649    AJWK01012650    GANO01001954    JAB57917.1    GEZM01071539    GEZM01071538    JAV65717.1    UFQS01000121    UFQT01000121    SSX00062.1    SSX20442.1    CVRI01000044    CRK96819.1    AJVK01015319    AJVK01015320    CH902620    EDV31887.1    CH964214    EDW80383.1    CH480833    EDW46451.1    CM000361    CM002910    EDX05725.1    KMY91317.1    CH940654    EDW57862.1    CH954179    EDV54447.1    KQS61797.1    KQS61798.1    L06423    L07551    L07549    L07550    AE014134    AY069676    CM000158    EDW89944.1    KRJ98811.1    KRJ98812.1    CH916368    EDW03087.1    CH933807    EDW12214.2    GFDF01006307    JAV07777.1    JXUM01001078    JXUM01001079    JXUM01072215    KQ562708    KXJ75294.1    CH477214    EAT47581.1    AAAB01008835    EAA05800.4   

Proteomes

UP000005204    UP000283053    UP000218220    UP000007151    UP000053268    UP000007266    + More
UP000092461    UP000192223    UP000183832    UP000092462    UP000007801    UP000007798    UP000001292    UP000000304    UP000008792    UP000008711    UP000192221    UP000000803    UP000002282    UP000001070    UP000009192    UP000092445    UP000069940    UP000249989    UP000008820    UP000007062   

PRIDE

H9JEG7    O96041    Q05192   

Pfam

PF00105   zf-C4        + More
PF00104   Hormone_recep

Interpro

IPR016355   NR5_fam        + More
IPR001723   Nuclear_hrmn_rcpt       
IPR035500   NHR-like_dom_sf       
IPR000536   Nucl_hrmn_rcpt_lig-bd       
IPR001628   Znf_hrmn_rcpt       
IPR013088   Znf_NHR/GATA       

SUPFAM

SSF48508   SSF48508       

Gene 3D

1.10.565.10     3.30.50.10    

ProteinModelPortal

H9JEG7   A0A3S2LGD2   A0A2W1BQP5   A0A2A4K6H4   A0A212F644   A0A194PQ55   + More
O96041   A0A2H1WRM2   A0A0T6B6T1   D2A6H1   A0A1B0CHS9   U5EYK1   A0A1Y1L3R0   A0A1W4WWF8   A0A336K8C1   A0A1J1I9C9   A0A1B0DH33   B3MMC7   B4N7P4   B4IFM9   B4Q4C8   B4M9I6   B3NKS4   A0A1W4VAN9   Q05192-2   B4P6X5   Q05192   B4JC74   B4KH03   A0A1L8DN23   A0A1A9Z5M7   A0A182GKK1   A0A182GLJ0   Q17LN1   A0A1S4EYC9   Q7QGB9  

PDB

2A66     E-value=4.87503e-31,     Score=338

KEGG

692364    K08705 nuclear receptor subfamily 5 group A member 3 | (RefSeq) Hr39; nuclear hormone receptor FTZ-F

GO

GO:0003700   GO:0008270   GO:0005634   GO:0043565   GO:0003707   GO:0046872   GO:0003677   GO:0009888   GO:0045944   GO:0009755   GO:0003682   GO:0090575   GO:0000976   GO:0004879   GO:0035211   GO:0000978   GO:0060968   GO:0006355   GO:0016321   GO:0043401   GO:0050793   GO:0003676   GO:0016876   GO:0043039  

PANTHER

PTHR24086  

Subcellular location

Nucleus  

Length:

609

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00169

Exp number, first 60 AAs:

0.0008

Total prob of N-in:

0.00072

outside

1  -  609

 

 

Pi

29.940999

Theta

195.595042

Tajima's D

0.218975

CLR

123.809534

CSRT

0.428978551072446

Interpretation

Uncertain