Gene

KWMTBOMO08224

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr14(-):2238705-2243393      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon X-element       + More
Probable RNA-directed DNA polymerase from transposon BS      
RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.376 Nuclear   Reliability : 1.956

CDS

ATGGACGCTGTATTCGCGGAATTCCTCCGACTTCGCCACCCACAGCTCGCCTCAGAGTTTCAGGCCTTCAAGGCCAATCACACTGCGAGCCCTCTCGAGGACTCCGCCGCGCTCGCTGCTCCTGCGTCGCCTGTACCTGCGTGCAGAGCTTCTGCATTGAGCACCGCAGCCTCTGTCGTGCCTGCCGCTCCCGTGTCGCCTATACTGGCGAGAAAAGCTGCTGCGTCGTCCGCCGTGACCATCGTTTCAGCTGAGCGATCATCCGCGGCCTCCGTCGCGCCCTCTAAAACACCTACACTTGCTCGTAGGTCGCCTGCACCCGCCTCCTCGTGCTCCGACTCTGACTCAGACATGGAGGTCGACCTCGCCCCCGCCTCATTGACGGATGGATTCACCCTGGTACAGAAGGGTAAGAAGCGTGCCGCGGAGTCTCGAGCTCCCGCGGCCGCTAAAATTAGCAAAGCCGTGAACGCGTCGCGCCCCCGCCCTCAGACTCCCGTTGCGCCCCCAGCCCGTGCCACTCCGTCGCCGCGCCCGGTGGCACAAAATAAAACCCAGACCCCTCCCCCGGTTATCCTTCAGGAGAAGGCAGCTTGGGATCGAGTTTGCCTGGCCCTTAAGGCCAAAAATATAAATTTCACGAATGCCCGTAACCTCGCGAACGGCATTCAAATTAAGGTTCAAACACCCGACGACCATAGGGCCCTCTCTTCTTACCTCCGTAAGGAACGTATAAGTTTCCATACTTATACGCTCCAGGAGGAGCGCGAACTCCGCGTTGTAATACGCGGAATCCCTAAAGAGTTAGATGTAGAGCTCGTCAAGGCCGACCTTCTGGAACAAGGCCTACCAGTAAATTCAGTGCACCGCATGCACACCGGCCGCGGTAGGGAGCCATATAATATGGTTCTAGTCGCCCTCCAGCCTACCCCGAGGGAGACCCTACTTAAGCCCGCGCGCCGTGACCCTAAAATCGCGAACTATAACATGGTCAGGAACGACAGGCTCTCTGCCCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCGCTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGACCGTTCTAAGCAGTGATATCGAGGCGCTGCTCGGTATGGGGAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATCAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGGCTTGACGCGTTAGTCGATGATCTCGCCTTCGATATTGTCGCTCCGCTAACCCCGACCCACTATCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAACCCGGACTCTATCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCTTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATGTCCTCGATACGCGCCTACGACAGGTATCCTACCGCGGAAAATCGTATTCGAATGCGTGCCCTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCCTCGTAGGCCCCTCAGGCCGACTCACGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGACGTAGAACGCAGAGCCTCCTTGCCACCATCGGATGCGTTACCACCCGTCACCCCGATAGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGAGGGTATATCTAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCCTTCTCATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTTGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATATGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCTACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCTGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCAATTCGGAAATACATGAAGTCAGCGTCGGAACGATACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTTGCATTAGATGCCTTCAGCTCTAATACTAGGGGCAGGCTTAGGGACCCCGGTAACCGTACTCGTCGAACTCGACAAAGAGGTCGACGTGCAACCTAA

Protein

MDAVFAEFLRLRHPQLASEFQAFKANHTASPLEDSAALAAPASPVPACRASALSTAASVVPAAPVSPILARKAAASSAVTIVSAERSSAASVAPSKTPTLARRSPAPASSCSDSDSDMEVDLAPASLTDGFTLVQKGKKRAAESRAPAAAKISKAVNASRPRPQTPVAPPARATPSPRPVAQNKTQTPPPVILQEKAAWDRVCLALKAKNINFTNARNLANGIQIKVQTPDDHRALSSYLRKERISFHTYTLQEERELRVVIRGIPKELDVELVKADLLEQGLPVNSVHRMHTGRGREPYNMVLVALQPTPRETLLKPARRDPKIANYNMVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKTVLSSDIEALLGMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTLRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFNPDSIPSPQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDDMSSIRAYDRYPTAENRIRMRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARTLKSDTVVTMPPLVGPSGRLTAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSDVERRASLPPSDALPPVTPIEVKDLIKDLRPRKAPGSEGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKLYERLLYKRLRDFVSSKGLLIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIWDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSNTRGRLRDPGNRTRRTRQRGRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.
Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon X-element

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   V5GNJ2   A0A139WA11   V5GNF3   X1WLB2   X1WNI2   A0A023EYS8   J9LC21   X1WZH0   A0A2J7QR37   A0A2J7PU96   A0A2J7QY69   A0A2J7PBY3   A0A2S2QEE0   A0A2J7R7D0   A0A087UCW3   K7IN67   A0A2J7Q6J2   A0A224XB44   A0A2S2Q383   A0A224X6Q4   J9LFC9   A0A224XI99   A0A1Y1KFR3   A0A224X6S1   A0A224X6U5   A0A069DZL8   A0A2M4BD67   A0A2M4BDV6   A0A2S2NH02   A0A087UGF5   A0A2S2R9D4   A0A224XJI0   A0A2M4CV52   A0A224X746   A0A023F069   A0A2M4CV42   Q07995   A0A3N5Z7I3   A0A224XIB0   A0A2S2NPG3   Q9NBX4   A0A2M4BD83   A0A224X6W2   Q95SX7   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A2H8TKI9   A0A2S2P698   A0A2J7Q0S7   P21328   A0A069DX78   A0A224X724   A0A2S2PHL7   A0A2J7Q9Z1   A0A2J7PSM7   A0A2J7R4U3  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    20075255    26334808    8387152    30086797    11405632    7753626    12537569    2463954    3040362    1714378   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    GALX01005299    JAB63167.1    KQ971729    KYB24751.1    GALX01005359    JAB63107.1    ABLF02042518    ABLF02057746    ABLF02008153    ABLF02008462    ABLF02008464    GBBI01004395    JAC14317.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    ABLF02034467    NEVH01011985    PNF31054.1    NEVH01021205    PNF19912.1    NEVH01009134    PNF33528.1    NEVH01027074    PNF13841.1    GGMS01006359    MBY75562.1    NEVH01006736    PNF36716.1    KK119261    KFM75202.1    NEVH01017470    PNF24199.1    GFTR01008262    JAW08164.1    GGMS01002992    MBY72195.1    GFTR01008279    JAW08147.1    ABLF02023911    GFTR01008256    JAW08170.1    GEZM01084969    JAV60363.1    GFTR01008271    JAW08155.1    GFTR01008251    JAW08175.1    GBGD01000415    JAC88474.1    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    GGMR01003864    MBY16483.1    KK119692    KFM76444.1    GGMS01017365    MBY86568.1    GFTR01008257    JAW08169.1    GGFL01004957    MBW69135.1    GFTR01008151    JAW08275.1    GBBI01003810    JAC14902.1    GGFL01005012    MBW69190.1    S59870    AAB26437.2    RPOV01000134    RPJ78669.1    GFTR01008246    JAW08180.1    GGMR01006408    MBY19027.1    AF237761    AAF81411.1    GGFJ01001822    MBW50963.1    GFTR01008260    JAW08166.1    AY060438    AAL25477.1    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    GFXV01002840    MBW14645.1    GGMR01012305    MBY24924.1    NEVH01019963    PNF22185.1    M22874    M38643    GBGD01000389    JAC88500.1    GFTR01008169    JAW08257.1    GGMR01016296    MBY28915.1    NEVH01016340    PNF25410.1    NEVH01021925    PNF19341.1    NEVH01007402    PNF35856.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000054359    UP000002358    + More

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q9NBX4    Q95SX7    P21328    + More

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   V5GNJ2   A0A139WA11   V5GNF3   X1WLB2   X1WNI2   A0A023EYS8   J9LC21   X1WZH0   A0A2J7QR37   A0A2J7PU96   A0A2J7QY69   A0A2J7PBY3   A0A2S2QEE0   A0A2J7R7D0   A0A087UCW3   K7IN67   A0A2J7Q6J2   A0A224XB44   A0A2S2Q383   A0A224X6Q4   J9LFC9   A0A224XI99   A0A1Y1KFR3   A0A224X6S1   A0A224X6U5   A0A069DZL8   A0A2M4BD67   A0A2M4BDV6   A0A2S2NH02   A0A087UGF5   A0A2S2R9D4   A0A224XJI0   A0A2M4CV52   A0A224X746   A0A023F069   A0A2M4CV42   Q07995   A0A3N5Z7I3   A0A224XIB0   A0A2S2NPG3   Q9NBX4   A0A2M4BD83   A0A224X6W2   Q95SX7   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A2H8TKI9   A0A2S2P698   A0A2J7Q0S7   P21328   A0A069DX78   A0A224X724   A0A2S2PHL7   A0A2J7Q9Z1   A0A2J7PSM7   A0A2J7R4U3  

KEGG

105841788    no KO assigned | (RefSeq) predicted GPI-anchored protein 58

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

1201

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

8.11326999999998

Exp number, first 60 AAs:

0.00071

Total prob of N-in:

0.00011

outside

1  -  1201

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0.431184

CSRT

0

Interpretation

Uncertain