Gene

KWMTBOMO07825

Pre Gene Modal

BGIBMGA000930

Annotation

PREDICTED:_chromatin-remodeling_complex_ATPase_chain_Iswi_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr13(+):7531373-7542361      View in EpiBrowser

Full name

Chromatin-remodeling complex ATPase chain Iswi      

Alternative Name

CHRAC 140 kDa subunit
Nucleosome-remodeling factor 140 kDa subunit
Protein imitation swi

Transcription factor

MYB

Location in the cell

Nuclear   Reliability : 3.963

CDS

ATGGCCCAGTCGGATGATGCCATGGACGTTGCCGATATTGGCGACAATTCCAATGGCTCTTCAAGTGACACGACATCTTCAAGAGGGAAAGAAGGTGATTTCGAGAGTAAGATTGAAACTGATCGTTCCAAGAGATTCGATTTTCTACTAAAGCAAACGGAGATATTTTCTCATTTTATGACCAACACTCCAAAATCTGGTGGGAGTCCTCCAAAACCAAAGGCTGGCAGACCCAGAAAGATAAAAATAGATACTGAACCTGAAGGTCCTGGAGATCACAGACATAGAAAAACTGAGCAAGAAGAAGATGAAGAACTTCTGGCAGAAACAAATTCAAAACAAAAGACAATATTTAGATTTGAAGCATCTCCACATTACATAAAAAATGGAGAAATGCGGGATTATCAAGTTAGAGGGCTTAACTGGATGATATCATTGTATGAAAATGGTATTAATGGAATTTTGGCTGATGAAATGGGTCTAGGAAAAACTTTGCAAACAATTTCTCTACTTGGATATATGAAACATTTTAAAAACGTTCCTGGTCCTCACATAGTAATTGTACCAAAATCCACTTTGACAAATTGGATGAACGAATTTAAAAAGTGGTGCCCTTCACTAAAAGCTGTGTGTCTTATTGGTGATCAAGAAACAAGGAATACATTTATCCGAGAAACCTTGATGCCTGGAAACTGGGATGTTTGCATTACATCATATGAAATGATTATAAGAGAGAAATCTGTCTTTAAAAAGTTTAACTGGCGTTATATGGTGATTGATGAGGCTCACCGTATCAAGAATGAAAAATCTAAATTATCGGAGCTGCTTAGGGAATTTAAGAGTATGAACAGGTTGCTGTTAACTGGTACTCCCTTGCAAAATAATCTCCATGAGTTGTGGGCACTATTGAATTTCCTTCTGCCTGATGTTTTTAATAGTTCTGATGACTTTGACTCATGGTTTAATACAAATGCAGCCCTAGGTGATAACCAATTGGTTTCACGTTTACATGCTGTACTAAGACCATTTTTGCTTCGGAGACTCAAATCTGAGGTTGAGAAAAAATTAAAGCCTAAAAAGGAATTAAAAGTTTATGTGGGTTTGAGTAAAATGCAAAGAGAGTGGTATACTAAGGTTCTTATGAAGGATATTGATGTAGTAAATGGTGCTGGAAAGGTTGAAAAAATGCGACTCCAGAACATTCTTATGCAGCTACGCAAATGTTGTAACCATCCTTATTTATTTGATGGCGCTGAGCCGGGTCCACCGTACACAACTGATGAACATTTAGTATATAACTGTGGTAAACTTACTATACTGGATAAGCTTTTACCTAAGCTTCAGGAGCAAGAGTCGAGAGTACTTATTTTCTCACAAATGACTAGGATGCTGGACATCTTAGAAGATTATTGCCTTTGGAGGCAATATAAGTATTGCCGTCTAGATGGTCAAACACCACATGAAGATAGAAATCGACAAATAGAAGAGTATAATATGGAGGGGAGTGAGAAATTTGTTTTTATGTTATCTACACGAGCTGGTGGTCTTGGTATTAACTTAACATCAGCTGATGTTGTTATTATTTATGACTCTGATTGGAATCCTCAAATGGATCTGCAGGCCATGGATAGAGCTCACCGTATTGGTCAGAAAAAGCAGGTCAGAGTGTTCCGTTTGATAACAGACAACACGGTTGAAGAAAAGATTGTAGAACGTGCGGAAGTGAAATTGCGCCTGGACAAACTTGTAATTCAGTCCGGTAGACTGGTCGACACTAAGAACCAGCTGAACAAAGATGAGATGCTCAACATGATCAGACATGGTGCCAACCACGTCTTTGCGTCTAAGGATTCTGAGGTTACTGATGAGGACATCGATACGATTTTAGCTAAAGGAGAGAGCAAGACTGAGGAGTTGAAGCAGAAATTGGAGAGCCTGGGCGAGTCGTCCTTGCGAGCATTTTCAATGGACACTCCTGGCGCGACCACCGACTCAGTTTATCAATTTGAAGGCGAGGATTACAGAGAGAAGCAAAAAGTTATCCCAATGGGTAGTTGGATAGAGCCGCCTAAGCGCGAACGTAAAGCTAATTATGCCGTGGACGCCTACTTCAGAGAGGCTCTACGTGTATCTGAACCGAAGGCGCCAAAGGTACAGGCTCCGCGTCCTCCGAAGCAGCCCATCGTACAGGATTTCCAGTTTTTCCCACCACGACTTTTTGAGTTGCTTGATCAAGAAATATATCATTATCGCAAAACCTTAGGATATAAAGTTCCACGTAATCCAGAATTGGGTCCAGATGCAGCGAAAATTCAGAGAGAGGAACAGAGAAAAATAGATGAGGCAGAAGCGCTTTCTGAAGAAGAAGTCCAAGAAAAAGAACAATTACTAACTCAAGGTTTCACTAATTGGACAAAACGTGATTTTAACCAGTTCATAAAAGCAAATGAAAAATACGGACGAGACGATATCGAGAATATTGCAAAAGATGTTGAAGGAAAAACACCAGAAGAGGTTATGGAGTACTCAGCTGTATTTTGGGAACGTTGCCACGAACTTCAAGATATAGATCGAATTATGGGCCAGATCGAAAGGGGCGAGGCTAAAATTCAACGACGAGCCTCTATTAAGAAAGCGTTGGACGCTAAAATGGCGCGGTACCGAGCACCATTCCACCAACTTAGAATCTCTTATGGAACAAACAAGGGCAAAAATTATGTTGAAGAGGAAGACAGGTTCTTGGTGTGCATGCTGCACAAGTTAGGATTCGATAAAGAAAACGTATACGAGGAACTTCGGGCTGCGGTACATTCCGCGCCACAGTTTCGTTTCGATTGGTTTCTAAAGTCAAGAACAGCCGTCGAATTACAACGTCGTTGCAATACGCTCATTACTTTAATTGAACGAGAGAATCAAGAGCTTGAAGAGAAAGAACGAGCCGAAAAGAAAAAGAAAAGCGGGAACGTCAATCCAAGTACGCCAGGCGGCAACGCGGCTGGCAAAGGCGCTAACGCAGGCAAACGCAAAGCTGACAACACTACTGATAGTGCACAGAAACAGAAGAAAAAGAAAACTAAGTAA

Protein

MAQSDDAMDVADIGDNSNGSSSDTTSSRGKEGDFESKIETDRSKRFDFLLKQTEIFSHFMTNTPKSGGSPPKPKAGRPRKIKIDTEPEGPGDHRHRKTEQEEDEELLAETNSKQKTIFRFEASPHYIKNGEMRDYQVRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYMKHFKNVPGPHIVIVPKSTLTNWMNEFKKWCPSLKAVCLIGDQETRNTFIRETLMPGNWDVCITSYEMIIREKSVFKKFNWRYMVIDEAHRIKNEKSKLSELLREFKSMNRLLLTGTPLQNNLHELWALLNFLLPDVFNSSDDFDSWFNTNAALGDNQLVSRLHAVLRPFLLRRLKSEVEKKLKPKKELKVYVGLSKMQREWYTKVLMKDIDVVNGAGKVEKMRLQNILMQLRKCCNHPYLFDGAEPGPPYTTDEHLVYNCGKLTILDKLLPKLQEQESRVLIFSQMTRMLDILEDYCLWRQYKYCRLDGQTPHEDRNRQIEEYNMEGSEKFVFMLSTRAGGLGINLTSADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITDNTVEEKIVERAEVKLRLDKLVIQSGRLVDTKNQLNKDEMLNMIRHGANHVFASKDSEVTDEDIDTILAKGESKTEELKQKLESLGESSLRAFSMDTPGATTDSVYQFEGEDYREKQKVIPMGSWIEPPKRERKANYAVDAYFREALRVSEPKAPKVQAPRPPKQPIVQDFQFFPPRLFELLDQEIYHYRKTLGYKVPRNPELGPDAAKIQREEQRKIDEAEALSEEEVQEKEQLLTQGFTNWTKRDFNQFIKANEKYGRDDIENIAKDVEGKTPEEVMEYSAVFWERCHELQDIDRIMGQIERGEAKIQRRASIKKALDAKMARYRAPFHQLRISYGTNKGKNYVEEEDRFLVCMLHKLGFDKENVYEELRAAVHSAPQFRFDWFLKSRTAVELQRRCNTLITLIERENQELEEKERAEKKKKSGNVNPSTPGGNAAGKGANAGKRKADNTTDSAQKQKKKKTK

Description

Energy-transducing component of the chromatin-remodeling complexes NURF (nucleosome-remodeling factor), ACF (ATP-utilizing chromatin assembly and remodeling factor), and CHRAC (chromatin accessibility complex). NURF catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. It is required for homeotic gene expression, proper larval blood cell development, normal male X chromosome morphology, ecdysteroid signaling and metamorphosis.

Subunit

Component of the NURF complex composed of Caf1, E(bx), Nurf-38 and Iswi.

Similarity

Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.

Keywords

3D-structure   ATP-binding   Chromatin regulator   Complete proteome   Direct protein sequencing   Helicase   Hydrolase   Nucleotide-binding   Nucleus   Phosphoprotein   Reference proteome   Repeat   Transcription   Transcription regulation  

Feature

chain  Chromatin-remodeling complex ATPase chain Iswi

Uniprot

H9IUK0   A0A3S2M3L3   A0A2A4J6A3   A0A194PE21   A0A194RHI3   A0A2A3EKC5   + More
A0A088AD04   E9J0E8   A0A195D2P0   F4WVR7   A0A195AVE5   A0A158NHJ8   A0A026WY91   A0A195E2G8   A0A0J7KIG5   E2B9I7   E1ZUT6   A0A151WGL1   A0A195ETL2   A0A347ZJC0   A0A067QXN5   A0A1B6F8Z9   A0A1L8DX53   A0A1B6L2G5   A0A1Y1N2R0   A0A0T6AVN9   D2A0V0   A0A1B6LR13   N6TRI1   A0A140EFS4   A0A1B6D198   A0A0V0G5M6   A0A1B6DS76   A0A069DXR6   A0A224X652   A0A023F5M6   A0A0L7LDD4   A0A1A9Y4I8   A0A1A9UHG4   A0A1B0FC35   A0A1B6CZS2   U5EY61   A0A1B6DLC0   A0A0L0BM44   A0A0K8V959   A0A140HIP5   W8BJN0   A0A034W4D0   A0A1B0BDV8   Q17E28   A0A2J7PFH7   A0A1Q3FVQ5   A0A146MER1   B4KSQ1   T1PG32   B4LP81   B4P567   A0A182QS89   Q24368   A0A182PM09   B4JVM2   B4HPM3   B3NRX4   B4MPP2   A0A0J9RB86   A0A182K1E3   A0A1W4VCW9   A0A182HDN8   A0A182NPB7   A0A2H8TUH5   A0A336LUD4   A0A1I8PAI2   A0A336L7N6   A0A182V9B1   A0A182UDP2   A0A182KV13   A0A1J1HS29   A0A154PFP8   A0A2S2N6D8   A0A182WXY1   Q7QE14   A0A182I603   A0A182YAD0   A0A084WNI5   A0A182ILL8   J9JUM4   A0A182FPM1   A0A0M4EHL5   A0A2M4ADG5   A0A3B0JKQ6   A0A182RLT6   W5JX29   A0A2M3Z6B9   A0A2M4BBQ4   A0A2S2PX75   Q293F0   B3MCU3   A0A0P5WKE3   E9GJ81   A0A0P4Y4S5  

EC Number

3.6.4.-

Pubmed

19121390    26354079    21282665    21719571    21347285    24508170    + More
30249741    20798317    24845553    28004739    18362917    19820115    23537049    26873291    26334808    25474469    26227816    26108605    24495485    25348373    17510324    26823975    17994087    25315136    17550304    7908117    10731132    12537572    12537569    8521502    8521501    12502740    16264191    18327897    14536084    18057021    22936249    26483478    20966253    12364791    14747013    17210077    25244985    24438588    20920257    23761445    15632085    23185243    21292972   

EMBL

BABH01000943    BABH01000944    RSAL01000047    RVE50528.1    NWSH01002871    PCG67409.1    + More
KQ459606    KPI91273.1    KQ460205    KPJ16899.1    KZ288220    PBC32177.1    GL767462    EFZ13700.1    KQ976973    KYN06634.1    GL888393    EGI61737.1    KQ976737    KYM75944.1    ADTU01015861    KK107069    QOIP01000002    EZA60706.1    RLU25869.1    KQ979763    KYN19271.1    LBMM01007091    KMQ90049.1    GL446556    EFN87620.1    GL434297    EFN75028.1    KQ983167    KYQ46964.1    KQ981975    KYN31578.1    FX985688    BBA84426.1    KK853132    KDR10882.1    GECZ01027479    GECZ01023119    GECZ01012067    GECZ01006744    JAS42290.1    JAS46650.1    JAS57702.1    JAS63025.1    GFDF01003088    JAV10996.1    GEBQ01022131    JAT17846.1    GEZM01017029    JAV90955.1    LJIG01022699    KRT79177.1    KQ971338    EFA01629.1    GEBQ01013948    JAT26029.1    APGK01022501    KB740427    ENN80673.1    KT369803    AML25532.1    GEDC01017819    JAS19479.1    GECL01002730    JAP03394.1    GEDC01008780    JAS28518.1    GBGD01000268    JAC88621.1    GFTR01008471    JAW07955.1    GBBI01002242    JAC16470.1    JTDY01001600    KOB73409.1    CCAG010005008    GEDC01018356    JAS18942.1    GANO01000571    JAB59300.1    GEDC01010815    JAS26483.1    JRES01001654    KNC21121.1    GDHF01016922    JAI35392.1    KT364640    AMO13047.1    GAMC01005065    JAC01491.1    GAKP01010339    GAKP01010336    GAKP01010334    GAKP01010332    JAC48618.1    JXJN01012713    CH477287    EAT44710.1    NEVH01025657    PNF15090.1    GFDL01003354    JAV31691.1    GDHC01000351    JAQ18278.1    CH933808    EDW10550.1    KA646843    AFP61472.1    CH940648    EDW60190.1    CM000158    EDW90729.1    KRJ99412.1    AXCN02001819    L27127    AE013599    AY094908    BT044562    CH916375    EDV98490.1    CH480816    EDW47607.1    CH954179    EDV56276.1    KQS62809.1    CH963849    EDW74081.1    CM002911    KMY93291.1    KMY93292.1    JXUM01034587    JXUM01034588    JXUM01034589    KQ561029    KXJ79969.1    GFXV01005656    MBW17461.1    UFQS01000115    UFQT01000115    SSW99899.1    SSX20279.1    UFQS01001832    UFQT01001832    SSX12485.1    SSX31928.1    CVRI01000020    CRK90821.1    KQ434889    KZC10274.1    GGMR01000096    MBY12715.1    AAAB01008848    EAA07020.3    APCN01003539    ATLV01024612    KE525353    KFB51779.1    ABLF02027798    CP012524    ALC42097.1    GGFK01005498    MBW38819.1    OUUW01000001    SPP75940.1    ADMH02000117    ETN67784.1    GGFM01003293    MBW24044.1    GGFJ01001322    MBW50463.1    GGMS01000826    MBY70029.1    CM000071    EAL24661.2    KRT01441.1    KRT01442.1    CH902619    EDV37345.1    KPU76736.1    GDIP01097883    JAM05832.1    GL732547    EFX80401.1    GDIP01232760    GDIP01183470    GDIP01069741    LRGB01000084    JAI90641.1    KZS21056.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000053268    UP000053240    UP000242457    + More
UP000005203    UP000078542    UP000007755    UP000078540    UP000005205    UP000053097    UP000279307    UP000078492    UP000036403    UP000008237    UP000000311    UP000075809    UP000078541    UP000027135    UP000007266    UP000019118    UP000037510    UP000092443    UP000078200    UP000092444    UP000037069    UP000092460    UP000008820    UP000235965    UP000009192    UP000095301    UP000008792    UP000002282    UP000075886    UP000000803    UP000075885    UP000001070    UP000001292    UP000008711    UP000007798    UP000075881    UP000192221    UP000069940    UP000249989    UP000075884    UP000095300    UP000075903    UP000075902    UP000075882    UP000183832    UP000076502    UP000076407    UP000007062    UP000075840    UP000076408    UP000030765    UP000075880    UP000007819    UP000069272    UP000092553    UP000268350    UP000075900    UP000000673    UP000001819    UP000007801    UP000000305    UP000076858   

PRIDE

H9IUK0    Q24368   

Pfam

PF09110   HAND        + More
PF00176   SNF2_N
PF13892   DBINO
PF00271   Helicase_C
PF09111   SLIDE
PF00089   Trypsin

Interpro

IPR029915   ISWI_metazoa        + More
IPR015195   SLIDE       
IPR038718   SNF2-like_sf       
IPR027417   P-loop_NTPase       
IPR036306   ISWI_HAND-dom_sf       
IPR000330   SNF2_N       
IPR017884   SANT_dom       
IPR001650   Helicase_C       
IPR009057   Homeobox-like_sf       
IPR015194   ISWI_HAND-dom       
IPR001005   SANT/Myb       
IPR020838   DBINO       
IPR014001   Helicase_ATP-bd       
IPR001254   Trypsin_dom       
IPR009003   Peptidase_S1_PA       

SUPFAM

SSF46689   SSF46689        + More
SSF52540   SSF52540       
SSF101224   SSF101224       
SSF50494   SSF50494       

Gene 3D

1.10.1040.30     3.40.50.10810    

CDD

cd00079  HELICc
cd00167  SANT

ProteinModelPortal

H9IUK0   A0A3S2M3L3   A0A2A4J6A3   A0A194PE21   A0A194RHI3   A0A2A3EKC5   + More
A0A088AD04   E9J0E8   A0A195D2P0   F4WVR7   A0A195AVE5   A0A158NHJ8   A0A026WY91   A0A195E2G8   A0A0J7KIG5   E2B9I7   E1ZUT6   A0A151WGL1   A0A195ETL2   A0A347ZJC0   A0A067QXN5   A0A1B6F8Z9   A0A1L8DX53   A0A1B6L2G5   A0A1Y1N2R0   A0A0T6AVN9   D2A0V0   A0A1B6LR13   N6TRI1   A0A140EFS4   A0A1B6D198   A0A0V0G5M6   A0A1B6DS76   A0A069DXR6   A0A224X652   A0A023F5M6   A0A0L7LDD4   A0A1A9Y4I8   A0A1A9UHG4   A0A1B0FC35   A0A1B6CZS2   U5EY61   A0A1B6DLC0   A0A0L0BM44   A0A0K8V959   A0A140HIP5   W8BJN0   A0A034W4D0   A0A1B0BDV8   Q17E28   A0A2J7PFH7   A0A1Q3FVQ5   A0A146MER1   B4KSQ1   T1PG32   B4LP81   B4P567   A0A182QS89   Q24368   A0A182PM09   B4JVM2   B4HPM3   B3NRX4   B4MPP2   A0A0J9RB86   A0A182K1E3   A0A1W4VCW9   A0A182HDN8   A0A182NPB7   A0A2H8TUH5   A0A336LUD4   A0A1I8PAI2   A0A336L7N6   A0A182V9B1   A0A182UDP2   A0A182KV13   A0A1J1HS29   A0A154PFP8   A0A2S2N6D8   A0A182WXY1   Q7QE14   A0A182I603   A0A182YAD0   A0A084WNI5   A0A182ILL8   J9JUM4   A0A182FPM1   A0A0M4EHL5   A0A2M4ADG5   A0A3B0JKQ6   A0A182RLT6   W5JX29   A0A2M3Z6B9   A0A2M4BBQ4   A0A2S2PX75   Q293F0   B3MCU3   A0A0P5WKE3   E9GJ81   A0A0P4Y4S5  

PDB

6K1P     E-value=0,     Score=2052

KEGG

101744798    K11654 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

GO

GO:0005524   GO:0003677   GO:0031491   GO:0016887   GO:0043044   GO:0016589   GO:0005634   GO:0004386   GO:0008094   GO:0070615   GO:0016584   GO:0008134   GO:0045944   GO:0008623   GO:0035092   GO:0045892   GO:0031213   GO:0035063   GO:0042766   GO:0035041   GO:0042752   GO:0005667   GO:0006334   GO:0016590   GO:0006351   GO:0035076   GO:0005700   GO:0003678   GO:0006325   GO:0031010   GO:0045893   GO:0006355   GO:0000166   GO:0006333   GO:0006357   GO:0006338   GO:0007283   GO:0004252   GO:0003676   GO:0016818   GO:0003707   GO:0051537  

PANTHER

PTHR10799:SF819  

Subcellular location

Nucleus  

Length:

1026

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02241

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00110

outside

1  -  1026

 

 

Pi

183.192187

Theta

175.589347

Tajima's D

-0.539453

CLR

10.16452

CSRT

0.228438578071096

Interpretation

Uncertain