Gene

KWMTBOMO07435

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr12(-):13157233-13162001      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey       + More
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.372 Nuclear   Reliability : 2.061

CDS

ATGGAGGAAAAACTTTTCATCGACTTCATTCGGGAAAAATATCCGTCAATCGCGCCCGAATTCGAAGCCTATAGGGCCTCATTTGGTAATTATTCTCCCCCCGCATCTCTCGCCGCCGTCGCCAAACATGCCTCGCAGGCATGCCTCGCGTGCCCCGCCGCCGGTCCGTGTTCAAGCGAGGACCGCGAACTCCGCGTAGTGATACGTGGAGTCCCCAAGGAACTCGACATAGACTACGTAAAGGAGGATCTGATCGGTCAGTCCCTCCCAATAATTAGTGTGCACCGGATGCACAGCGGACGCGGCAGACAGCCGTACAATATGATTCTCGTCGCGCTAGAATCAACCCCGGAGGCAAAGAAAAGAATCTCATGTCTCAAAACGATATGCGGCCTCTCCGGGGTCACCATCGAAGCCCCCATAAACGTGGTACTCCCGGGCAGTGCCACAGCATTCTACAATGCTAACGGACTCGCGCGGCAACGCGATCAAATTTTCGAATTCCTCCGCGATAATCTTGTAGATATTTTGTTAGTGCAGGAGACCTGTCTGAAGCCCTCGCGTCGTGACCCGAAAGTCGCGAATTACGTCATGGTTAGGAATGACAGACTCACCGCCTCCAAAGGCGGGACTGCCATTTACTATAGGCGGGCTCTGCACGTTGTTCCTCTCGATACTCCCTCGCTCTTACATATCGAGGCGTCAGTGTGCCGTATCTCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCGGACAAGCCCCTCCTGAGCAGTGACATCGAGTCACTGTTTGGCATGGGAGACTCCGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCATCGTACGAACGTTAACGGTAGGCGTCTCGACGCGTTTATAGACGACCTCACTTTTGAAGTAGTCGGTCCCCCAACTCCAACATGTTATCCGTATAACATCGCGCTCCGTCCGAGCACTATAGACCTGGCATTGCTTAGGAACGTAACTCTGCGCTTACGTTCCATCGAAGCACTGTCAGAGCTCGACTCAGACCACCGACCTGTCCTTATGCAGCTCGGTCGCCCTCACAACCCAGCCACTGTTACGAGGACCATGGTGGATTGGAATAAGCTGGGCACGTGCCTAGCCGAAGCCGCTCCGCCAATCCTCCCTTACGGCCCGGATACGAATCTATCCCCCGAGGACACCGTCGAATCCATAAACATCATTACCGATCACATCTCTTCCGCGATCATTAGATCTTCAAAAGAAGTCGATGTGGAGGACAGCTTCCACCGCATCAGACTGTCCTCCGAACTTAGGAATCTCTTAAGAGTTAGGAACGCGGCAATCCGGGCCTACGACCGTCTTCCCACGCATTCAAACCGGATTAGGATGCGTCGTCTACAACGCGAAGTCCACTCCCGCCTAAGTGACGCGCGTAACGATAATTGGCATAGTTATTTAGAACAACTCGCGCCCTCCCACCAAGCATACTGGCGACTAGCTAGGACTCTCAAATCCGAAACTACCGCTACTATGCCTCCCCTCGTACGCCCTTCAGGCCAACCACCGGCATTCGATGACGATGACAAGGCTGAGCTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCGCCCTCGGACGCGTTACCCCCCATTACCACTGACGAAGTTAGAGACGCGATACACAACCTCCAACCTAGGAAGGCACCCGGCTCCGACGGCATCCGCAACCGCGCGCTAAAACTCTTGCCAGTCCAACTGATAGCAATGTTGGCTACAATTTTAAATGCCGCTATGACGCACTGCATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGTATACATAAGCCGGGCAAACCGACAAACGAAACTTCTAGTTACCGTCCGATTAGTCTCCTCCCGACGATAGGAAAAATTTACGAACGGCTCCTTAGGAAACGCCTCTGGGATTTTGTTACCGCGAACAAAATTCTCATAGACGAACAGTTCGGATTCCGCTCTAAACACTCGTGCGTACAACAAATGCACCGCCTCACGGAGCACATCCTGATAGGACTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTCTTCGACATCGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTAATTTACAAACTGTACAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTTCTTGTCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCAACTGACTGCCGGAGTCCCGCAAGGCTCCGCGCTCTCCCCGTTATTATTTAGTTTGTATATCAAAGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGATGACACGGCTATCTACTACTCGTGTAGGAAGATGTCGCTGCTTTTTCGGCGACTCCAGATCGCAGTAGCCACCATGGGACAGTGGTTCCGGAAGTGGCGCATCGACATCAACCCCACGAAAAGCACAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAATACCACTTCGAGCATCCCACTCCCTAATAGGCGCGCAAACACCTCCGCCGTTAGCCCCGTCACTCTCTTTGGCCAGCCCATACCGTGGGCCTCGCAGGTCAAATACCTAGGCGTCACCCTCGACAGAGGGATGACATTCCGTCCCCATATTAAAACGGTACGCGACCGTGCCGCCTTCATATTAGGACGTCTCTACCCTATGCTTTGCAAGCGAAGCAAACTGTCCCTCCGTAATAAGAACTAG

Protein

MEEKLFIDFIREKYPSIAPEFEAYRASFGNYSPPASLAAVAKHASQACLACPAAGPCSSEDRELRVVIRGVPKELDIDYVKEDLIGQSLPIISVHRMHSGRGRQPYNMILVALESTPEAKKRISCLKTICGLSGVTIEAPINVVLPGSATAFYNANGLARQRDQIFEFLRDNLVDILLVQETCLKPSRRDPKVANYVMVRNDRLTASKGGTAIYYRRALHVVPLDTPSLLHIEASVCRISLTGHQPIVIASVYLPPDKPLLSSDIESLFGMGDSVILAGDLNCHHTRWNCHRTNVNGRRLDAFIDDLTFEVVGPPTPTCYPYNIALRPSTIDLALLRNVTLRLRSIEALSELDSDHRPVLMQLGRPHNPATVTRTMVDWNKLGTCLAEAAPPILPYGPDTNLSPEDTVESINIITDHISSAIIRSSKEVDVEDSFHRIRLSSELRNLLRVRNAAIRAYDRLPTHSNRIRMRRLQREVHSRLSDARNDNWHSYLEQLAPSHQAYWRLARTLKSETTATMPPLVRPSGQPPAFDDDDKAELLADALQEQCTTSTQHADPEHTELVDREVERRASLPPSDALPPITTDEVRDAIHNLQPRKAPGSDGIRNRALKLLPVQLIAMLATILNAAMTHCIFPAVWKEADVIGIHKPGKPTNETSSYRPISLLPTIGKIYERLLRKRLWDFVTANKILIDEQFGFRSKHSCVQQMHRLTEHILIGLNRRKQIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDFLSNRSFRYRVEGTRSRPRQLTAGVPQGSALSPLLFSLYIKDIPRSPETHLALFADDTAIYYSCRKMSLLFRRLQIAVATMGQWFRKWRIDINPTKSTAVLFKRGRPPNTTSSIPLPNRRANTSAVSPVTLFGQPIPWASQVKYLGVTLDRGMTFRPHIKTVRDRAAFILGRLYPMLCKRSKLSLRNKN

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A139W8G9   + More
A0A1Y1NA23   A0A139WA11   D7EM17   A0A023EYS8   V5GNF3   V5GNJ2   A0A2S2PPK8   A0A023EZE6   X1WNI2   Q07995   A0A2S2Q383   A0A3N5Z7I3   X1WLB2   J9LC21   A0A2J7QR37   A0A2J7PBY3   A0A2J7QY69   A0A2M4CV42   A0A2M4CV52   A0A2S2QEE0   A0A2J7RE85   A0A2J7PU96   A0A2J7R7D0   A0A2M4BD66   A0A224X6Q4   A0A2S2PA10   A0A2M4BD62   A0A2M4BDA5   J9LFC9   A0A087UGF5   X1WZH0   A0A224X6T4   A0A2J7Q6J2   A0A224XF24   A0A1Y1K0C8   A0A087UCW3   A0A2S2NJB5   A0A2S2NGV8   A0A2S2N814   A0A224X6S1   A0A2J7PP17   V9H092   A0A224XB44   J9KLB1   A0A087U3K8   A0A2S2R9D4   A0A2S2P698   A0A224XI99   K7IN67   A0A224X746   J9M522   A0A2J7QB68   J9JS95   A0A224XHW8   A0A1Y1KFR3   A0A224X6U5   A0A2S2PJG2   X1WQI9   A0A2H8TF37   A0A2J7PDM0   A0A2M4CVF1   A0A2M4CVK2   A0A2J7PVX3   A0A2M4BEF4   A0A0J7MTN6   A0A224X7Z3   A0A0H3UA66   A0A2M4BEZ9   A0A224X6R6   A0A146KRW8   P21328   A0A0A9YJ00   A0A0A9YU04   A0A0V0G5B6   A0A087T3W0   A0A3S2NJ07   A0A069DX78   A0A224XJI0   A0A2A4IUM2   A0A2S2N6Q7   D7GYA5   A0A0A9YSX4   A0A224X6W2   A0A2S2NPG3   A0A1B6EGD8   A0A2S2P6S3   Q95SX7   A0A1Y1LKN6   A0A2S2NH02  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    18362917    19820115    28004739    + More
25474469    8387152    30086797    9061921    20075255    26812285    26823975    2463954    3040362    1714378    25401762    26334808    7753626    12537569   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    KQ973342    KXZ75569.1    GEZM01008457    JAV94772.1    KQ971729    KYB24751.1    KQ973412    EFA12510.2    GBBI01004395    JAC14317.1    GALX01005359    JAB63107.1    GALX01005299    JAB63167.1    GGMR01018716    MBY31335.1    GBBI01004571    JAC14141.1    ABLF02008153    ABLF02008462    ABLF02008464    S59870    AAB26437.2    GGMS01002992    MBY72195.1    RPOV01000134    RPJ78669.1    ABLF02042518    ABLF02057746    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    NEVH01011985    PNF31054.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    GGFL01005012    MBW69190.1    GGFL01004957    MBW69135.1    GGMS01006359    MBY75562.1    NEVH01005277    PNF39135.1    NEVH01021205    PNF19912.1    NEVH01006736    PNF36716.1    GGFJ01001844    MBW50985.1    GFTR01008279    JAW08147.1    GGMR01013409    MBY26028.1    GGFJ01001843    MBW50984.1    GGFJ01001842    MBW50983.1    ABLF02023911    KK119692    KFM76444.1    ABLF02034467    GFTR01008261    JAW08165.1    NEVH01017470    PNF24199.1    GFTR01008038    JAW08388.1    GEZM01099921    GEZM01099920    GEZM01099918    GEZM01099906    JAV53125.1    KK119261    KFM75202.1    GGMR01004661    MBY17280.1    GGMR01003407    MBY16026.1    GGMR01000676    MBY13295.1    GFTR01008271    JAW08155.1    NEVH01023280    PNF18085.1    L79944    AAB04627.1    GFTR01008262    JAW08164.1    ABLF02040174    ABLF02040183    ABLF02055266    KK118005    KFM71947.1    GGMS01017365    MBY86568.1    GGMR01012305    MBY24924.1    GFTR01008256    JAW08170.1    GFTR01008151    JAW08275.1    ABLF02024246    NEVH01016302    PNF25823.1    ABLF02028535    ABLF02028545    GFTR01008254    JAW08172.1    GEZM01084969    JAV60363.1    GFTR01008251    JAW08175.1    GGMR01016905    MBY29524.1    ABLF02022418    GFXV01000908    MBW12713.1    NEVH01026386    PNF14434.1    GGFL01005122    MBW69300.1    GGFL01005121    MBW69299.1    NEVH01020940    PNF20481.1    GGFJ01002256    MBW51397.1    LBMM01018163    KMQ83860.1    GFTR01007929    JAW08497.1    KF280391    AIE77315.1    GGFJ01002257    MBW51398.1    GFTR01008269    JAW08157.1    GDHC01020244    JAP98384.1    M22874    M38643    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GECL01003538    JAP02586.1    KK113281    KFM59799.1    RSAL01000708    RVE41206.1    GBGD01000389    JAC88500.1    GFTR01008257    JAW08169.1    NWSH01007753    PCG62823.1    GGMR01000226    MBY12845.1    KQ973363    EFA13335.2    GBHO01008295    JAG35309.1    GFTR01008260    JAW08166.1    GGMR01006408    MBY19027.1    GEDC01000337    JAS36961.1    GGMR01012443    MBY25062.1    AY060438    AAL25477.1    GEZM01053022    JAV74219.1    GGMR01003864    MBY16483.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000054359    UP000002358    + More
UP000036403    UP000283053    UP000218220   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    P21328    Q95SX7   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A139W8G9   + More
A0A1Y1NA23   A0A139WA11   D7EM17   A0A023EYS8   V5GNF3   V5GNJ2   A0A2S2PPK8   A0A023EZE6   X1WNI2   Q07995   A0A2S2Q383   A0A3N5Z7I3   X1WLB2   J9LC21   A0A2J7QR37   A0A2J7PBY3   A0A2J7QY69   A0A2M4CV42   A0A2M4CV52   A0A2S2QEE0   A0A2J7RE85   A0A2J7PU96   A0A2J7R7D0   A0A2M4BD66   A0A224X6Q4   A0A2S2PA10   A0A2M4BD62   A0A2M4BDA5   J9LFC9   A0A087UGF5   X1WZH0   A0A224X6T4   A0A2J7Q6J2   A0A224XF24   A0A1Y1K0C8   A0A087UCW3   A0A2S2NJB5   A0A2S2NGV8   A0A2S2N814   A0A224X6S1   A0A2J7PP17   V9H092   A0A224XB44   J9KLB1   A0A087U3K8   A0A2S2R9D4   A0A2S2P698   A0A224XI99   K7IN67   A0A224X746   J9M522   A0A2J7QB68   J9JS95   A0A224XHW8   A0A1Y1KFR3   A0A224X6U5   A0A2S2PJG2   X1WQI9   A0A2H8TF37   A0A2J7PDM0   A0A2M4CVF1   A0A2M4CVK2   A0A2J7PVX3   A0A2M4BEF4   A0A0J7MTN6   A0A224X7Z3   A0A0H3UA66   A0A2M4BEZ9   A0A224X6R6   A0A146KRW8   P21328   A0A0A9YJ00   A0A0A9YU04   A0A0V0G5B6   A0A087T3W0   A0A3S2NJ07   A0A069DX78   A0A224XJI0   A0A2A4IUM2   A0A2S2N6Q7   D7GYA5   A0A0A9YSX4   A0A224X6W2   A0A2S2NPG3   A0A1B6EGD8   A0A2S2P6S3   Q95SX7   A0A1Y1LKN6   A0A2S2NH02  

PDB

6AR3     E-value=0.00437733,     Score=98

KEGG

105842435    no KO assigned | (RefSeq) uncharacterized LOC105842435

GO

GO:0003964   GO:0004519   GO:0016021   GO:0006313  

Length:

953

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.890829999999999

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.00283

outside

1  -  953

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

16.780137

CSRT

0

Interpretation

Uncertain