Gene

KWMTBOMO05671

Pre Gene Modal

BGIBMGA006839

Annotation

AF332550_1_orphan_nuclear_receptor_E75A_[Bombyx_mori]

Location

Bomo_Chr10(-):7662047-7677742      View in EpiBrowser

Full name

Ecdysone-inducible protein E75      

Alternative Name

Nuclear receptor subfamily 1 group D member 3

Transcription factor

THR-like

Location in the cell

Nuclear   Reliability : 4.334

CDS

ATGTCTCCGGATAGTAGCTACGGGCGCTACGATGTGCCTACGTCCGTCGACCACTCTTTGATGAGTTCGATGCACAAGGAACGTGAACCTGAATTGCATATAGAATTTGACGGTACCACGGTTCTGTGCCGCGTCTGTGGCGACAAGGCCAGTGGGTTCCACTACGGCGTCCACTCCTGCGAGGGCTGCAAGGGCTTCTTCCGGCGATCTATACAACAGAAGATACAATACCGGCCCTGCACGAAGAACCAGCAGTGTAGTATCCTCAGGATTAACAGGAATCGGTGCCAGTATTGCCGACTGAAAAAATGCATCGCCGTCGGAATGAGCAGAGATGCTGTGCGATTCGGTCGTGTACCCAAACGCGAGAAAGCGCGTATCCTCGCAGCGATGCAACAGTCGTCGTCGTCTCGTGCACACGAGCAAGCAGCTGCCGCTGAACTTGATGACGCTCCTCGGTTGCTGGCGCGAGTGGTGCGCGCTCATCTCGACACGTGCGAGTTCACGCGTGATCGCGTCGCTTCCATGCGAGCCAGAGCTCGCGACTGTCCCACCTACTCGCAGCCTACTCTGGCTTGCCCACTAAACCCGGCGCCAGAGCTGCAATCTGAAAAGGAATTTTCGCAACGTTTCGCCCATGTGATACGTGGCGTGATTGACTTTGCCGGCCTCATCCCTGGCTTCCAGCTGCTGACCCAAGATGACAAATTCACGCTGCTCAAAAGTGGTCTGTTCGATGCATTGTTCGTGCGACTCATCTGTATGTTTGACGCTCCTCTTAATAGTATCATCTGTCTCAATGGGCAACTGATGAAGAGAGACTCCATCCAGAGCGGTGCCAATGCAAGGTTTCTCGTTGATTCTACTTTCAAGTTTGCGGAACGTATGAATTCCATGAATTTGACGGACGCGGAAATAGGACTTTTCTGTGCTATAGTCCTCATCACTCCGGATCGGCCTGGCCTGCGAAACATAGAGCTAGTGGAAAGAATGCACTCGCGACTGAAGGCGTGCTTGCAAACTGTCATTGCACAGAACAGGCCAGAGAGACCTGGGTTTTTAAGAGAATTAATGGATACATTACCTGATTTACGCACTTTAAGCACGCTTCACACAGAAAAACTTGTTGTTTTCCGAACGGAACATAAGGAGTTATTGCGTCAACAAATGTGGAATGAAGAAGAAGGTGTTTCCTGGGCCGATTCCGTAGTGGAGGAATCAGCTCGTAGCCCCATCGGGTCTGTATCCAGCAGCGAGTCCGGGGAGGTGCCGAGTGACTGTGGCACTCCTTTACTGGCAGCAACGTTGGCCGGTCGCCGGCGACTTGACTCTCGGGGCTCTGTCGATGAAGAAGCTCTCGGCGTCGCACATCTGGCTCACAACGGACTCACCGTGACGCCCGTCCGCCCTCCTCCCCGGTATCGGAAGTTGGATTCCCCGACTGATTCGGGTATTGAATCTGGCAACGAGAAACACGAGAGGATAATCGGACCCGGGTCGGGTTGTTCTAGTCCGCGGTCGTCCTTAGAAGAGCACACCGAGGACAGACGGCCCACCGCGCCCGCCGATGACATGCCCGTGCTCAAACGTGTGCTTCAGGCTCCACCTTTGTACGGCGGAACTTCTACATTGATGGATGAAACCTACAAACCACACAAGAAATTCCGCGCTATGAGGCGCGACACCGGAGAAGCAGAGGCTCGTCCAGTGCAGCCGACGCCGTCGCCACAGCCGCTGCACCCGCACCCGGCCAGTCCGGCTCATCCGGCTCATTCGCCGCGACCACCGCGCATTTCTCTGTCATCCACGCATTCGGTGCTCGCTAAAAGTTTAATGGAGGGGCCGAGAATGACTCCTGAACAATTAAAACGTACCGATATGATCCAGCAGTACATGCGGCGAAATGAAGCTGGTTCTAGTGTGGAAGGATGTCCGCTGCGAACTGGAGGGCTGCTGACCTGCTACCGCGGTGCGTCTCCGGCTCCGCCGCCAGTGCTGGCGCTGCAGGTGGACGTGACGGACGCGCCGCTGAACCTCTCCAAGAAGTCGCCGTCGCCGCCTCGTTCGTACATGCCGCAGATGTTAGAGGCGTGA

Protein

MSPDSSYGRYDVPTSVDHSLMSSMHKEREPELHIEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQSSSSRAHEQAAAAELDDAPRLLARVVRAHLDTCEFTRDRVASMRARARDCPTYSQPTLACPLNPAPELQSEKEFSQRFAHVIRGVIDFAGLIPGFQLLTQDDKFTLLKSGLFDALFVRLICMFDAPLNSIICLNGQLMKRDSIQSGANARFLVDSTFKFAERMNSMNLTDAEIGLFCAIVLITPDRPGLRNIELVERMHSRLKACLQTVIAQNRPERPGFLRELMDTLPDLRTLSTLHTEKLVVFRTEHKELLRQQMWNEEEGVSWADSVVEESARSPIGSVSSSESGEVPSDCGTPLLAATLAGRRRLDSRGSVDEEALGVAHLAHNGLTVTPVRPPPRYRKLDSPTDSGIESGNEKHERIIGPGSGCSSPRSSLEEHTEDRRPTAPADDMPVLKRVLQAPPLYGGTSTLMDETYKPHKKFRAMRRDTGEAEARPVQPTPSPQPLHPHPASPAHPAHSPRPPRISLSSTHSVLAKSLMEGPRMTPEQLKRTDMIQQYMRRNEAGSSVEGCPLRTGGLLTCYRGASPAPPPVLALQVDVTDAPLNLSKKSPSPPRSYMPQMLEA

Description

Orphan receptor possibly involved in the regulation of genes in the ecdysteroid cascade.

Similarity

Belongs to the nuclear hormone receptor family.
Belongs to the nuclear hormone receptor family. NR1 subfamily.

Keywords

Alternative splicing   DNA-binding   Metal-binding   Nucleus   Receptor   Transcription   Transcription regulation   Zinc   Zinc-finger  

Feature

chain  Ecdysone-inducible protein E75
splice variant  In isoform 2.

Uniprot

Q9U5G4   Q8WSA2   Q8WSA1   Q8WSA0   Q08893   A0A2A4JNX7   + More
Q9U5G3   A0A1Z2RRH7   P50239   A0A385JFT9   H9JBE4   A0A3S2L0A7   A0A2A4JMV6   O01639   Q08893-2   A0A0H5AGH4   A0A2A4JNF1   A0A2A4JMS7   Q6Q2C9   P50239-2   A0A0N9K0Z2   A0A385JGL2   A0A0L7LVR1   A0A2H1V6C8   A0A212EIJ9   A0A2A4JM07   E3UJZ7   H6WNA6   A0A1L8DG45   S4PMV4   A0A1S4FGD0   Q172G0   A0A194PE27   A0A194QMD3   A0A1S4FGE6   Q0JRL0   A0A1Q3G4W0   A0A1S4FGC2   Q0JRL1   B0WMI3   A0A1B0DPK1   A0A1L8DNG9   A4UU55   A0A1S3DV33   A4UU56   A0A069DWY0  

Pubmed

11180812    12429116    8485520    28605547    8174547    19121390    + More
9094210    15233798    26325588    26227816    22118469    22044719    23622113    10411302    17510324    26354079    19580803    26334808   

EMBL

AB024904    BAA89262.1    AF332550    AAL57047.1    AF332551    AAL57048.1    + More
AF332552    AAL57049.2    S60738    S60782    U73683    NWSH01001013    PCG73120.1    AB024905    BAA89263.1    KY938811    ASA46452.1    U02620    U51008    MG346172    AXY96564.1    BABH01030811    RSAL01000312    RVE42664.1    PCG73116.1    U63930    LC011420    BAR88292.1    PCG73114.1    PCG73119.1    AY566195    AAS75597.1    KT363833    ALG36652.1    MG346173    AXY96565.1    JTDY01000002    KOB79520.1    ODYU01000662    SOQ35824.1    AGBW02014631    OWR41304.1    PCG73115.1    HM445736    ADO64597.1    JQ266225    AEZ00699.1    GFDF01008668    JAV05416.1    GAIX01003355    JAA89205.1    AM397060    CH477438    CAL36974.1    EAT40908.2    KQ459606    KPI91517.1    KQ461198    KPJ06115.1    AM397062    CAL36975.1    GFDL01000211    JAV34834.1    AM397061    CAL36973.1    EJY57686.1    DS231998    EDS31054.1    AJVK01008138    GFDF01006180    JAV07904.1    EF490808    ABP02024.1    EF490809    ABP02025.1    GBGD01000677    JAC88212.1   

Proteomes

UP000218220    UP000005204    UP000283053    UP000037510    UP000007151    UP000008820    + More
UP000053268    UP000053240    UP000002320    UP000092462    UP000079169   

PRIDE

Q9U5G4    Q8WSA2    Q8WSA1    Q8WSA0    Q08893    Q9U5G3    + More
P50239    H9JBE4    O01639   

Pfam

PF00105   zf-C4        + More
PF00104   Hormone_recep

Interpro

IPR035500   NHR-like_dom_sf        + More
IPR001723   Nuclear_hrmn_rcpt       
IPR013088   Znf_NHR/GATA       
IPR001728   ThyrH_rcpt       
IPR001628   Znf_hrmn_rcpt       
IPR000536   Nucl_hrmn_rcpt_lig-bd       

SUPFAM

SSF48508   SSF48508       

Gene 3D

1.10.565.10     3.30.50.10    

ProteinModelPortal

Q9U5G4   Q8WSA2   Q8WSA1   Q8WSA0   Q08893   A0A2A4JNX7   + More
Q9U5G3   A0A1Z2RRH7   P50239   A0A385JFT9   H9JBE4   A0A3S2L0A7   A0A2A4JMV6   O01639   Q08893-2   A0A0H5AGH4   A0A2A4JNF1   A0A2A4JMS7   Q6Q2C9   P50239-2   A0A0N9K0Z2   A0A385JGL2   A0A0L7LVR1   A0A2H1V6C8   A0A212EIJ9   A0A2A4JM07   E3UJZ7   H6WNA6   A0A1L8DG45   S4PMV4   A0A1S4FGD0   Q172G0   A0A194PE27   A0A194QMD3   A0A1S4FGE6   Q0JRL0   A0A1Q3G4W0   A0A1S4FGC2   Q0JRL1   B0WMI3   A0A1B0DPK1   A0A1L8DNG9   A4UU55   A0A1S3DV33   A4UU56   A0A069DWY0  

PDB

3E00     E-value=7.57799e-50,     Score=500

KEGG

692595    K08701 nuclear receptor subfamily 1 group D member 3 | (RefSeq) E75, E75D; nuclear hormone receptor

GO

GO:0008270   GO:0043565   GO:0003707   GO:0005634   GO:0004879   GO:0046872   GO:0003677   GO:0003700   GO:0006355   GO:0004887   GO:0043401  

Subcellular location

Nucleus  

Length:

697

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.20582

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00534

outside

1  -  697

 

 

Pi

217.61379

Theta

199.451465

Tajima's D

0.517554

CLR

0.883535

CSRT

0.514424278786061

Interpretation

Uncertain