Silkworm Genome Informatics Database

Gene

KWMTBOMO04021

Pre Gene Modal

BGIBMGA010110

Annotation

PREDICTED:_mothers_against_decapentaplegic_homolog_4_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr7(-):9090727-9095660 View in EpiBrowser

Full name

Mothers against decapentaplegic homolog

Alternative Name

SMAD family member

Transcription factor

MH1

Location in the cell

Nuclear Reliability : 4.247

CDS

ATGAATACGACAGCACCAACATCGGCAGATGCATGCCTCAGCATTGTGCATTCACTGATGTGCCACCGTCAAGGTGGTGAGAGCGAAGGATTTTCTAAACGAGCCATTGAATCTCTGGTCAAGAAGTTGAAAGAAAAACGAGATGAGCTTGACTCTTTGATCACAGCTATAACTACAAATGGTGCACATCCTAGTAAATGTGTTACTATACAGAGGACTTTAGATGGGAGATTACAGGTTGCTGGTCGGAAAGGATTTCCTCATGTAATTTATGCTCGAATATGGAGGTGGCCAGATTTACATAAAAATGAACTGAAACATGTTAAATTTTGTCAATTTGCATTTGATTTAAAGTGTGACTCTGTGTGTGTTAATCCATACCACTATGAAAGAGTTGTTTCTCCTGGTATAGATTTATCCGGCTTGTCCCTTCAATCTGGACCCAGTAGATTAGTAAAGGACGAGTACACGGCTGGTCTAGGTGGTAACGGTATGGACATGGATACTGGTGAGATGGTTACCATACAGCATCATGCGACAAGTCCTAGACACCACCATTCGACAATACAACATCACCATCAACAGTTTCAAACAACTAATATTATTATGAATCAAGGACAGACGCCCGATGGCGTTCCGAGCATGTTTTCACCGACCCACGGGCCCCGGACGCCGATCCGGCCTTCGGGTGGTCCATCCCAGTTACCACCGCCGCCTTCCATGGGACACTCGCCGAGCGCACAAATGATGCAAAATCACACGGGACAAATGCCCACACCGCAGATGGTACCGGGGGCTTCACAACTACGATCGGGAACGCCCCAAATGGGACCCGCTACGCCACAAATGGTCCCCGGAACACCACAGATGGTGCCCGGTAATCCGCAAATGGTACCGAACACCCCGCAAATGGGGCCGGGCACACCGCAGATGGGTCCCAGTACTCCGCAAATGGGTCCGGGCACGCCACAGATGGGACCCGGTACACCTCAGATGGGTCCGGGTACACCTCAGATGGGATCAAATGTACCTCAAATGGCTTCGCCGAGAATGGCTTCGGCCCCCACGCAGATGTCTCCGGGGACCCCCCAGATGCCTTCGATTAGTCAGGGAATGTCCATACCGAGCCCGCAACAAATGGTGATGCAGCAAAGAGCCATAGCCCCTAAGCTGGAGCCACCCGACACCATGGACGCCCGAGCTATGTGGCTGCCAAAAAGAATGAATCATTCGGCGATACCAGTAAGTATGTCGCCAGGCGCGACGACGCCTCTTATCGATGGTGCGAACACGACGTTCTTCGGCACAGAACAAACCACTACCGACACACAAATCACACAGACTCTCCCTACTGGCACAGTTTCACCGATAACCGGTGAGGGTACACAACAGAACGGGTTTGCTGCGACCAGTCCAGCACCGCAACCTAGTCCTCTTCAGCACCAGAGCCAACCACAGCCACCTCAGCAGCAACAACAACAACAGCAGCAGCAGGGTAACAAGTCATTTTCTTTTTGA

Protein

MNTTAPTSADACLSIVHSLMCHRQGGESEGFSKRAIESLVKKLKEKRDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHVKFCQFAFDLKCDSVCVNPYHYERVVSPGIDLSGLSLQSGPSRLVKDEYTAGLGGNGMDMDTGEMVTIQHHATSPRHHHSTIQHHHQQFQTTNIIMNQGQTPDGVPSMFSPTHGPRTPIRPSGGPSQLPPPPSMGHSPSAQMMQNHTGQMPTPQMVPGASQLRSGTPQMGPATPQMVPGTPQMVPGNPQMVPNTPQMGPGTPQMGPSTPQMGPGTPQMGPGTPQMGPGTPQMGSNVPQMASPRMASAPTQMSPGTPQMPSISQGMSIPSPQQMVMQQRAIAPKLEPPDTMDARAMWLPKRMNHSAIPVSMSPGATTPLIDGANTTFFGTEQTTTDTQITQTLPTGTVSPITGEGTQQNGFAATSPAPQPSPLQHQSQPQPPQQQQQQQQQQGNKSFSF

Similarity

Belongs to the dwarfin/SMAD family.

Uniprot

A0A212EUG5 A0A194PNF4 A0A194RR97 A0A0L7KHI5 A0A0N0P9E4

Pubmed

22118469 26354079 26227816

EMBL

AGBW02012412 OWR45094.1 KQ459600 KPI94269.1 KQ459995 KPJ18561.1 + More
JTDY01009886 KOB62349.1 KQ459470 KPJ00239.1

Proteomes

UP000007151 UP000053268 UP000053240 UP000037510

Pfam

PF03165   MH1        + More
PF03166   MH2
PF00400   WD40

Interpro

IPR013019   MAD_homology_MH1        + More
IPR001132   SMAD_dom_Dwarfin-type
IPR017855   SMAD-like_dom_sf
IPR013790   Dwarfin
IPR008984   SMAD_FHA_dom_sf
IPR036578   SMAD_MH1_sf
IPR003619   MAD_homology1_Dwarfin-type
IPR015943   WD40/YVTN_repeat-like_dom_sf
IPR017986   WD40_repeat_dom
IPR001680   WD40_repeat
IPR036322   WD40_repeat_dom_sf

SUPFAM

SSF56366   SSF56366        + More
SSF49879   SSF49879
SSF50978   SSF50978

Gene 3D

2.60.200.10 3.90.520.10 2.130.10.10

ProteinModelPortal

A0A212EUG5 A0A194PNF4 A0A194RR97 A0A0L7KHI5 A0A0N0P9E4

PDB

3QSV E-value=3.02305e-65, Score=632

KEGG

101745398 K04501 mothers against decapentaplegic homolog 4 | (RefSeq) mothers against decapentaplegic homolog

PATHWAY

04068    FoxO signaling pathway - Bombyx mori (domestic silkworm)
04310    Wnt signaling pathway - Bombyx mori (domestic silkworm)
04350    TGF-beta signaling pathway - Bombyx mori (domestic silkworm)
04933    AGE-RAGE signaling pathway in diabetic complications - Bombyx mori (domestic silkworm)

GO

GO:0003677 GO:0005737 GO:0007179 GO:0005634 GO:0005667 GO:0003700 GO:0005622 GO:0006355 GO:0006811 GO:0006032 GO:0016021 GO:0004672 GO:0048384

PANTHER

PTHR13703

Subcellular location

Cytoplasm
Nucleus

Length:

505

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00478

Exp number, first 60 AAs:

0.0005

Total prob of N-in:

0.00496

outside

1 - 505

Pi

273.142973

Theta

205.829823

Tajima's D

1.256457

CLR

0

CSRT

0.731713414329283

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics