Gene

KWMTBOMO02984

Pre Gene Modal

BGIBMGA003622

Annotation

putative_Ciliary_dynein_heavy_chain_[Operophtera_brumata]

Location

Bomo_Chr5(-):15087047-15092275      View in EpiBrowser

Full name

Dynein beta chain, ciliary      

Location in the cell

Cytoplasmic   Reliability : 2.392

CDS

ATGCTGCCTCCAGTACCAACGACAGAAGGACTGGACCCTCTGACCATGCTGACCGATGACACGAACATTGCGATGTGGCAAAACGAAGGACTGCCTTCTGATAGAATGAGTACTGAAAATGCCACAATACTGTCCAACTCAGATCGTTGGCCGCTAATGATTGATCCTCAGTTGCAAGGCGTGAAGTGGATTAAACAGAAATATGGAGATATACTTCGTGTTATAAGACTCGGGCAGAAAGGTTATTTGGATACAATAGAGAAAGCTATTATTAAAGGAGAGACTGTTCTCTTAGAAAACATCGGTGAAACAGTCGACCCTGTACTAGATCCACTGCTCGGACGAAACCTAATTAAGAAGGGAAGAGCTATAAAGATCGGCGACAAGGAAATTGAATACAGTCCAAACTTTAGATTGATTTTACACACGAAATTAGCTAACCCACATTACAAGCCCGAGATGCAAGCTCAAACAACATTGGTCAATTTCACTGTAACGAGAGATGGGCTTGAGGATCAACTTCTGGCCGAAGTGGTGAAAGCTGAAAGACCAGATCTAGAAGAACTCAAAGCGGAGTTAACAAAACAACAGAATCAGTTCAAGATACAGCTGAAGGAGTTGGAAGATGATTTGCTTTCGCGTCTCTCAGCAGCCGGAGAGAATATATTAGGCGATACAGCTTTGGTTGAGAATTTAGAAACCACGAAAAAGACTGCTGCTGATATCGAGAAAAAGGTACTCCTCATGAGCGAAGAAATATCACCAGCAGAACTGGACTTTTTCCTACGTTTTCCAATTAAACCTCATGTCACTAGTCCTGTAGATTTCCTATCTAATCAAAGCTGGGGAGGGATATGTTCTCTGGCTGGTAAAGACGAATTTAGAAACCTGGATCGTGATATTGAAACGTCTCCTAAACGATGGAAGAAGATTGTTGAAATAGAATGTCCTGAAAGAGAAAAATTTCCACAGGTAAATTTTTATGGGCACAGCTGTAAAGTTTCCCCTGGCCGAGGACATTAA

Protein

MLPPVPTTEGLDPLTMLTDDTNIAMWQNEGLPSDRMSTENATILSNSDRWPLMIDPQLQGVKWIKQKYGDILRVIRLGQKGYLDTIEKAIIKGETVLLENIGETVDPVLDPLLGRNLIKKGRAIKIGDKEIEYSPNFRLILHTKLANPHYKPEMQAQTTLVNFTVTRDGLEDQLLAEVVKAERPDLEELKAELTKQQNQFKIQLKELEDDLLSRLSAAGENILGDTALVENLETTKKTAADIEKKVLLMSEEISPAELDFFLRFPIKPHVTSPVDFLSNQSWGGICSLAGKDEFRNLDRDIETSPKRWKKIVEIECPEREKFPQVNFYGHSCKVSPGRGH

Subunit

Consists of at least two heavy chains (alpha and beta), three intermediate chains and several light chains.

Similarity

Belongs to the dynein heavy chain family.

Keywords

3D-structure   ATP-binding   Cell projection   Cilium   Coiled coil   Cytoplasm   Cytoskeleton   Direct protein sequencing   Dynein   Flagellum   Microtubule   Motor protein   Nucleotide-binding   Repeat  

Feature

chain  Dynein beta chain, ciliary

Uniprot

A0A0L7LUC4   A0A182TS04   H9J285   A0A212FLC8   A0A2A4JJP5   A0A2H1X2P9   + More
A0A2R7WTH2   E0VLA6   A0A1B0EYP6   A0A182V866   A0A182RBC6   A0A182MNY4   A0A182YIP1   A0A2P8YQY7   A0A182W3T1   A0A1S4H4T4   Q5TUD8   A0A182JRE6   A0A182NDL4   A0A182LNA0   A0A182WR89   A0A182HX97   A0A2M4DP19   A0A182QB97   A0A2S2QK24   A0A182PVS5   B4N969   A0A0Q9X5F3   A0A1A9WGW2   A0A0L7QYM1   A0A0P8Y0J0   B3M2X7   A0A1I8PWQ2   B4KE24   B4JSY1   A0A0L0BTW6   A0A2M4A0B6   A0A182IVR3   A0A182FM39   Q71JD2   W5J456   A0A084VZI7   A0A154PPG4   B0WUU8   A0A1I8M6W5   A0A1I8M6W0   Q9VDG0   A0A0B4KHJ4   B4IKM6   A0A0R1E125   A0A1S4FKM6   A0A0R1E1G1   Q16XH8   B4PQ99   A0A182GMZ9   A0A0R1E127   A0A0R1E5P0   A0A1W4VLP2   A0A1W4VZS9   A0A0M4ELU1   B4GM15   B4M4V0   B3P2Z8   A0A139WPL9   D6W7L1   A0A3B0JSI1   Q293J4   A0A0R3NKH1   A0A1J1IHV8   A0A310S6L6   E2BE63   E2AYZ0   A0A151WVZ6   A0A151JXC9   A0A2A3EQV0   A0A195CXR3   S4RSC2   E9IZF0   A0A088AF70   A0A2S2PPS1   A0A2S2NTM3   A0A336KXF6   F4WD53   A0A3L8DCZ9   A0A026WFI7   A0A0J7P079   A0A151JQJ9   J9K4Q1   A0A158P169   A0A0M9AA00   A0A336M9T6   A0A195AUI3   T1HP15   U4UMC9   U6D7V7   K7F2D2   W4YN93   N6U0M0   P23098   P39057  

Pubmed

26227816    19121390    22118469    20566863    25244985    29403074    + More
12364791    20966253    17994087    26108605    20920257    23761445    24438588    25315136    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17550304    17510324    26483478    18362917    19820115    15632085    20798317    21282665    21719571    30249741    24508170    21347285    23537049    17381049    1830927    1833761    11250194    1830928   

EMBL

JTDY01000081    KOB78984.1    BABH01007454    BABH01007455    BABH01007456    BABH01007457    + More
AGBW02007827    OWR54500.1    NWSH01001294    PCG71814.1    ODYU01012953    SOQ59508.1    KK855459    PTY22671.1    AAZO01003313    DS235271    EEB14162.1    AJVK01064446    AXCM01000636    PYGN01000422    PSN46658.1    AAAB01008849    EAL41019.3    APCN01005160    GGFL01015101    MBW79279.1    AXCN02001753    GGMS01008884    MBY78087.1    CH964232    EDW81616.1    KRF99495.1    KQ414688    KOC63714.1    CH902617    KPU80296.1    EDV43507.1    CH933806    EDW16045.2    CH916373    EDV94871.1    JRES01001345    KNC23525.1    GGFK01000870    MBW34191.1    AF494076    AAQ06635.1    ADMH02002126    ETN58641.1    ATLV01018849    KE525251    KFB43381.1    KQ434980    KZC13060.1    DS232111    EDS35091.1    AE014297    AAF55834.3    AGB96173.1    CH480853    EDW51630.1    CM000160    KRK03004.1    KRK03001.1    CH477538    EAT39332.1    EDW96208.2    JXUM01075435    KQ562886    KXJ74924.1    KRK03003.1    KRK03002.1    CP012526    ALC46327.1    CH479185    EDW38589.1    CH940652    EDW59661.2    CH954181    EDV48312.1    KQ971307    KYB29781.1    EFA11309.2    OUUW01000007    SPP83382.1    CM000070    EAL29221.2    KRT01415.1    CVRI01000047    CRK98041.1    KQ767877    OAD53287.1    GL447755    EFN86050.1    GL444028    EFN61360.1    KQ982691    KYQ52109.1    KQ981572    KYN39778.1    KZ288199    PBC33642.1    KQ977141    KYN05431.1    GL767121    EFZ14108.1    GGMR01018852    MBY31471.1    GGMR01007858    MBY20477.1    UFQS01001276    UFQT01001276    SSX10081.1    SSX29803.1    GL888084    EGI67861.1    QOIP01000009    RLU18201.1    KK107235    EZA54880.1    LBMM01000571    KMQ98045.1    KQ978644    KYN29472.1    ABLF02030722    ABLF02030734    ABLF02030735    ABLF02030737    ABLF02030738    ADTU01005848    ADTU01005849    KQ435706    KOX80265.1    UFQS01000646    UFQT01000646    SSX05712.1    SSX26071.1    KQ976738    KYM75717.1    ACPB03010549    KB632384    ERL94272.1    HAAF01006872    CCP78696.1    AGCU01026795    AGCU01026796    AGCU01026797    AGCU01026798    AGCU01026799    AGCU01026800    AGCU01026801    AGCU01026802    AGCU01026803    AGCU01026804    AAGJ04100285    APGK01047112    APGK01047113    APGK01047114    APGK01047115    APGK01047116    APGK01047117    APGK01047118    KB741077    ENN74141.1    X59603    D01021   

Proteomes

UP000037510    UP000075902    UP000005204    UP000007151    UP000218220    UP000009046    + More
UP000092462    UP000075903    UP000075900    UP000075883    UP000076408    UP000245037    UP000075920    UP000007062    UP000075881    UP000075884    UP000075882    UP000076407    UP000075840    UP000075886    UP000075885    UP000007798    UP000091820    UP000053825    UP000007801    UP000095300    UP000009192    UP000001070    UP000037069    UP000075880    UP000069272    UP000000673    UP000030765    UP000076502    UP000002320    UP000095301    UP000000803    UP000001292    UP000002282    UP000008820    UP000069940    UP000249989    UP000192221    UP000092553    UP000008744    UP000008792    UP000008711    UP000007266    UP000268350    UP000001819    UP000183832    UP000008237    UP000000311    UP000075809    UP000078541    UP000242457    UP000078542    UP000245300    UP000005203    UP000007755    UP000279307    UP000053097    UP000036403    UP000078492    UP000007819    UP000005205    UP000053105    UP000078540    UP000015103    UP000030742    UP000007267    UP000007110    UP000019118   

PRIDE

H9J285    Q9VDG0    P23098    P39057   

Pfam

PF08393   DHC_N2        + More
PF12774   AAA_6
PF12781   AAA_9
PF03028   Dynein_heavy
PF12780   AAA_8
PF18198   AAA_lid_11
PF17852   Dynein_AAA_lid
PF18199   Dynein_C
PF12777   MT
PF17857   AAA_lid_1
PF08385   DHC_N1
PF07728   AAA_5

Interpro

IPR035699   AAA_6        + More
IPR041228   Dynein_C       
IPR042228   Dynein_2_C       
IPR041658   AAA_lid_11       
IPR041466   Dynein_AAA5_ext       
IPR003593   AAA+_ATPase       
IPR013594   Dynein_heavy_dom-1       
IPR013602   Dynein_heavy_dom-2       
IPR004273   Dynein_heavy_D6_P-loop       
IPR042219   AAA_lid_11_sf       
IPR026983   DHC_fam       
IPR024317   Dynein_heavy_chain_D4_dom       
IPR024743   Dynein_HC_stalk       
IPR027417   P-loop_NTPase       
IPR042222   Dynein_2_N       
IPR041589   DNAH3_AAA_lid_1       
IPR035706   AAA_9       
IPR011704   ATPase_dyneun-rel_AAA       
IPR009069   Cys_alpha_HP_mot_SF       
IPR036084   Ser_inhib-like_sf       
IPR030443   DNAH9       

SUPFAM

SSF52540   SSF52540        + More
SSF47072   SSF47072       
SSF57567   SSF57567       

Gene 3D

1.10.8.720     1.20.140.100     3.20.180.20    

ProteinModelPortal

A0A0L7LUC4   A0A182TS04   H9J285   A0A212FLC8   A0A2A4JJP5   A0A2H1X2P9   + More
A0A2R7WTH2   E0VLA6   A0A1B0EYP6   A0A182V866   A0A182RBC6   A0A182MNY4   A0A182YIP1   A0A2P8YQY7   A0A182W3T1   A0A1S4H4T4   Q5TUD8   A0A182JRE6   A0A182NDL4   A0A182LNA0   A0A182WR89   A0A182HX97   A0A2M4DP19   A0A182QB97   A0A2S2QK24   A0A182PVS5   B4N969   A0A0Q9X5F3   A0A1A9WGW2   A0A0L7QYM1   A0A0P8Y0J0   B3M2X7   A0A1I8PWQ2   B4KE24   B4JSY1   A0A0L0BTW6   A0A2M4A0B6   A0A182IVR3   A0A182FM39   Q71JD2   W5J456   A0A084VZI7   A0A154PPG4   B0WUU8   A0A1I8M6W5   A0A1I8M6W0   Q9VDG0   A0A0B4KHJ4   B4IKM6   A0A0R1E125   A0A1S4FKM6   A0A0R1E1G1   Q16XH8   B4PQ99   A0A182GMZ9   A0A0R1E127   A0A0R1E5P0   A0A1W4VLP2   A0A1W4VZS9   A0A0M4ELU1   B4GM15   B4M4V0   B3P2Z8   A0A139WPL9   D6W7L1   A0A3B0JSI1   Q293J4   A0A0R3NKH1   A0A1J1IHV8   A0A310S6L6   E2BE63   E2AYZ0   A0A151WVZ6   A0A151JXC9   A0A2A3EQV0   A0A195CXR3   S4RSC2   E9IZF0   A0A088AF70   A0A2S2PPS1   A0A2S2NTM3   A0A336KXF6   F4WD53   A0A3L8DCZ9   A0A026WFI7   A0A0J7P079   A0A151JQJ9   J9K4Q1   A0A158P169   A0A0M9AA00   A0A336M9T6   A0A195AUI3   T1HP15   U4UMC9   U6D7V7   K7F2D2   W4YN93   N6U0M0   P23098   P39057  

PDB

4RH7     E-value=5.28158e-41,     Score=421

KEGG

101743793    K10408 dynein heavy chain, axonemal | (RefSeq) dynein beta chain, ciliary-like

GO

GO:0030286   GO:0007018   GO:0005524   GO:0003777   GO:0045505   GO:0008569   GO:0005930   GO:0045503   GO:0051959   GO:0016887   GO:0016021   GO:0042623   GO:0003341   GO:0036157   GO:0005875   GO:0007605   GO:0005874   GO:0031514   GO:0030030   GO:0005737  

PANTHER

PTHR10676   PTHR10676:SF257  

Subcellular location

Cell projection  
Cilium  
Flagellum  
Cytoplasm  
Cytoskeleton  
Flagellum axoneme  

Length:

340

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00042

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00252

outside

1  -  340

 

 

Pi

27.351596

Theta

21.341972

Tajima's D

0.095214

CLR

105.151144

CSRT

0.406179691015449

Interpretation

Uncertain