Gene

KWMTBOMO02983

Pre Gene Modal

BGIBMGA003622

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_dynein_beta_chain?_ciliary-like_[Bombyx_mori]

Location

Bomo_Chr5(-):15085974-15086425      View in EpiBrowser

Full name

Dynein heavy chain 17, axonemal      

Alternative Name

Axonemal beta dynein heavy chain 17
Ciliary dynein heavy chain 17

Location in the cell

Cytoplasmic   Reliability : 1.718

CDS

ATGGGTTCGAAGTACGTTGAAAACAGGACGGTGGAGTTTAGTAAGTCCTTCGAAGAGACCAGTCCCACTACGCCGATATTCTTTATACTGTCCCCGGGTGTGAATCCTTTGAAGGACGTGGAGGCGCTCGGTAAGGTCATGGGGTTCACGGCTGATGCAGGAAACTTCCACAACGTGTCTTTGGGACAAGGACAGGAGATCGTCGCGGAACAGGCTATTGATGAGGCACTGCAAAAGGGCCATTGGGTTGTCTTACAGGTAAAGCTTTTGGCAGAATTATTTCTGTTCATCTCTAACGAGATCTTGATACCATCTACATATTTTTAA

Protein

MGSKYVENRTVEFSKSFEETSPTTPIFFILSPGVNPLKDVEALGKVMGFTADAGNFHNVSLGQGQEIVAEQAIDEALQKGHWVVLQVKLLAELFLFISNEILIPSTYF

Description

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity).

Subunit

Consists of at least two heavy chains and a number of intermediate and light chains.

Similarity

Belongs to the dynein heavy chain family.

Keywords

Alternative splicing   ATP-binding   Cell projection   Cilium   Coiled coil   Complete proteome   Cytoplasm   Cytoskeleton   Dynein   Kelch repeat   Microtubule   Motor protein   Nucleotide-binding   Reference proteome   Repeat   TPR repeat  

Feature

chain  Dynein heavy chain 17, axonemal
splice variant  In isoform 2.

Uniprot

H9J285   A0A212FLC8   A0A2H1X2P9   A0A0N1ID47   W8CAW5   A0A1B6ESP3   + More
A0A0R1E877   A0A336KXF6   A0A0L7LUC4   A0A336M9T6   A0A1B0EYP6   A0A084VZI7   A0A182IVR3   A0A232F8L3   A0A182MNY4   A0A1J1IHV8   A0A182SWG7   A0A2M4A0B6   A0A182QB97   A0A2J7RTA9   A0A2M4DP19   A0A182PVS5   A0A0P8Y0J0   B3M2X7   G3UDE0   A0A182YIP1   A0A182RBC6   A0A182W3T1   A0A2P8YQY7   W5J456   A0A2G8JUA6   A0A182V866   A0A182LNA0   A0A182JRE6   Q5TUD8   A0A1S4H4T4   H0VHA6   F1LRU2   A0A182WR89   A0A182HX97   G7PT15   A0A0D9S475   G7NH05   A0A182NDL4   A0A182FM39   A0A2A3EQV0   E9IZF0   A0A287AFU3   B0WUU8   A0A182TS04   B4N969   A0A1S4FKM6   A0A1I8M6W0   A0A0Q9X5F3   A0A1I8M6W5   F6RMY0   A0A182GMZ9   Q16XH8   A0A1I8PWQ2   B4GM15   A0A0R3NKH1   A0A3B0JSI1   Q293J4   S9X8X8   A0A2J7RTB7   E9Q7P0   K3W4R0   Q69Z23   H2NUW7   A0A1W2WA78   A0A2J7RTA2   B4JSY1   A0A2J8Y1Z7   A0A2J7RTA3   D4A599   A0A0R1E125   B4PQ99   A0A0R1E1G1   Q9VDG0   A0A2I2YF97   A0A0R1E5P0   A0A0B4KHJ4   A0A0R1E127   B4IKM6   B3P2Z8   A0A2J7RTA7   B4M4V0   B4R1N9   A0A096NT81   A0A2K6TUR9   A0A2J8K7W8   A0A2K5Z8J8   A0A2K6Q0W4   A0A2K5MWZ2   A0A1A9WGW2   G3QM43   F7HSA4   A0A2K5SD28   A0A2K5CCM6   A0A2R9B230  

Pubmed

19121390    22118469    26354079    24495485    17994087    17550304    + More
26227816    24438588    28648823    25244985    29403074    20920257    23761445    29023486    20966253    12364791    21993624    15057822    22002653    21282665    17510324    25315136    12481130    15114417    26483478    15632085    23149746    19468303    21183079    9373155    15368895    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    22398555    25362486    17431167    22722832   

EMBL

BABH01007454    BABH01007455    BABH01007456    BABH01007457    AGBW02007827    OWR54500.1    + More
ODYU01012953    SOQ59508.1    KQ461187    KPJ07329.1    GAMC01000989    JAC05567.1    GECZ01028797    JAS40972.1    CH892531    KRK05516.1    UFQS01001276    UFQT01001276    SSX10081.1    SSX29803.1    JTDY01000081    KOB78984.1    UFQS01000646    UFQT01000646    SSX05712.1    SSX26071.1    AJVK01064446    ATLV01018849    KE525251    KFB43381.1    NNAY01000755    OXU26657.1    AXCM01000636    CVRI01000047    CRK98041.1    GGFK01000870    MBW34191.1    AXCN02001753    NEVH01000006    PNF44064.1    GGFL01015101    MBW79279.1    CH902617    KPU80296.1    EDV43507.1    PYGN01000422    PSN46658.1    ADMH02002126    ETN58641.1    MRZV01001252    PIK39300.1    AAAB01008849    EAL41019.3    AAKN02047324    AAKN02047325    AABR07030872    AABR07030873    APCN01005160    CM001291    EHH58389.1    AQIB01144983    AQIB01144984    AQIB01144985    AQIB01144986    CM001268    EHH25255.1    KZ288199    PBC33642.1    GL767121    EFZ14108.1    AEMK02000080    DS232111    EDS35091.1    CH964232    EDW81616.1    KRF99495.1    JXUM01075435    KQ562886    KXJ74924.1    CH477538    EAT39332.1    CH479185    EDW38589.1    CM000070    KRT01415.1    OUUW01000007    SPP83382.1    EAL29221.2    KB016591    EPY86792.1    PNF44066.1    AL591204    AL591433    Z83807    AK173343    ABGA01014777    ABGA01014778    ABGA01014779    ABGA01014780    ABGA01014781    ABGA01014782    ABGA01014783    PNF44065.1    CH916373    EDV94871.1    NDHI03003284    PNJ88263.1    PNF44070.1    CM000160    KRK03004.1    EDW96208.2    KRK03001.1    AE014297    AAF55834.3    CABD030035838    CABD030035839    CABD030035840    CABD030035841    CABD030035842    CABD030035843    CABD030035844    CABD030035845    CABD030035846    KRK03002.1    AGB96173.1    KRK03003.1    CH480853    EDW51630.1    CH954181    EDV48312.1    PNF44067.1    CH940652    EDW59661.2    CM000364    EDX12148.1    AHZZ02010773    AHZZ02010774    AHZZ02010775    AHZZ02010776    AHZZ02010777    NBAG03000388    PNI31125.1    JSUE03017556    JSUE03017557    JSUE03017558    AJFE02062425    AJFE02062426    AJFE02062427    AJFE02062428    AJFE02062429    AJFE02062430    AJFE02062431   

Proteomes

UP000005204    UP000007151    UP000053240    UP000002282    UP000037510    UP000092462    + More
UP000030765    UP000075880    UP000215335    UP000075883    UP000183832    UP000075901    UP000075886    UP000235965    UP000075885    UP000007801    UP000007646    UP000076408    UP000075900    UP000075920    UP000245037    UP000000673    UP000230750    UP000075903    UP000075882    UP000075881    UP000007062    UP000005447    UP000002494    UP000076407    UP000075840    UP000009130    UP000029965    UP000075884    UP000069272    UP000242457    UP000008227    UP000002320    UP000075902    UP000007798    UP000095301    UP000008144    UP000069940    UP000249989    UP000008820    UP000095300    UP000008744    UP000001819    UP000268350    UP000000589    UP000001595    UP000001070    UP000000803    UP000001519    UP000001292    UP000008711    UP000008792    UP000000304    UP000028761    UP000233220    UP000233140    UP000233200    UP000233060    UP000091820    UP000006718    UP000233040    UP000233020    UP000240080   

PRIDE

H9J285    F1LRU2    E9Q7P0    K3W4R0    Q69Z23    D4A599    + More
Q9VDG0   

Pfam

PF03028   Dynein_heavy        + More
PF18198   AAA_lid_11
PF12780   AAA_8
PF18199   Dynein_C
PF17852   Dynein_AAA_lid
PF08385   DHC_N1
PF17857   AAA_lid_1
PF12777   MT
PF12774   AAA_6
PF08393   DHC_N2
PF12781   AAA_9
PF07728   AAA_5

Interpro

IPR042228   Dynein_2_C        + More
IPR041228   Dynein_C       
IPR041658   AAA_lid_11       
IPR035699   AAA_6       
IPR013594   Dynein_heavy_dom-1       
IPR026983   DHC_fam       
IPR042219   AAA_lid_11_sf       
IPR013602   Dynein_heavy_dom-2       
IPR004273   Dynein_heavy_D6_P-loop       
IPR003593   AAA+_ATPase       
IPR041466   Dynein_AAA5_ext       
IPR027417   P-loop_NTPase       
IPR024743   Dynein_HC_stalk       
IPR024317   Dynein_heavy_chain_D4_dom       
IPR041589   DNAH3_AAA_lid_1       
IPR035706   AAA_9       
IPR042222   Dynein_2_N       
IPR009069   Cys_alpha_HP_mot_SF       
IPR011704   ATPase_dyneun-rel_AAA       

SUPFAM

SSF52540   SSF52540        + More
SSF47072   SSF47072       

Gene 3D

1.10.8.720     1.20.140.100     3.20.180.20    

ProteinModelPortal

H9J285   A0A212FLC8   A0A2H1X2P9   A0A0N1ID47   W8CAW5   A0A1B6ESP3   + More
A0A0R1E877   A0A336KXF6   A0A0L7LUC4   A0A336M9T6   A0A1B0EYP6   A0A084VZI7   A0A182IVR3   A0A232F8L3   A0A182MNY4   A0A1J1IHV8   A0A182SWG7   A0A2M4A0B6   A0A182QB97   A0A2J7RTA9   A0A2M4DP19   A0A182PVS5   A0A0P8Y0J0   B3M2X7   G3UDE0   A0A182YIP1   A0A182RBC6   A0A182W3T1   A0A2P8YQY7   W5J456   A0A2G8JUA6   A0A182V866   A0A182LNA0   A0A182JRE6   Q5TUD8   A0A1S4H4T4   H0VHA6   F1LRU2   A0A182WR89   A0A182HX97   G7PT15   A0A0D9S475   G7NH05   A0A182NDL4   A0A182FM39   A0A2A3EQV0   E9IZF0   A0A287AFU3   B0WUU8   A0A182TS04   B4N969   A0A1S4FKM6   A0A1I8M6W0   A0A0Q9X5F3   A0A1I8M6W5   F6RMY0   A0A182GMZ9   Q16XH8   A0A1I8PWQ2   B4GM15   A0A0R3NKH1   A0A3B0JSI1   Q293J4   S9X8X8   A0A2J7RTB7   E9Q7P0   K3W4R0   Q69Z23   H2NUW7   A0A1W2WA78   A0A2J7RTA2   B4JSY1   A0A2J8Y1Z7   A0A2J7RTA3   D4A599   A0A0R1E125   B4PQ99   A0A0R1E1G1   Q9VDG0   A0A2I2YF97   A0A0R1E5P0   A0A0B4KHJ4   A0A0R1E127   B4IKM6   B3P2Z8   A0A2J7RTA7   B4M4V0   B4R1N9   A0A096NT81   A0A2K6TUR9   A0A2J8K7W8   A0A2K5Z8J8   A0A2K6Q0W4   A0A2K5MWZ2   A0A1A9WGW2   G3QM43   F7HSA4   A0A2K5SD28   A0A2K5CCM6   A0A2R9B230  

PDB

4RH7     E-value=0.0783299,     Score=77

KEGG

101743793    K10408 dynein heavy chain, axonemal | (RefSeq) dynein beta chain, ciliary-like

GO

GO:0003777   GO:0005524   GO:0007018   GO:0030286   GO:0016021   GO:0016887   GO:0045505   GO:0008569   GO:0005930   GO:0045503   GO:0051959   GO:0007605   GO:0005874   GO:0036157   GO:0042623   GO:0003341   GO:0005875   GO:0015379   GO:0003909   GO:0051103   GO:0003677   GO:0006281   GO:0048384  

PANTHER

PTHR10676  

Subcellular location

  

Length:

108

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.75397

Exp number, first 60 AAs:

0.01427

Total prob of N-in:

0.55461

inside

1  -  108

 

 

Pi

82.034413

Theta

149.038424

Tajima's D

-1.064557

CLR

679.817807

CSRT

0.124693765311734

Interpretation

Uncertain