Gene

KWMTBOMO02334

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr4(-):18198998-18203847      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon X-element      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.316 Nuclear   Reliability : 1.995

CDS

ATGGACGCTGTGTTCGCGGAATTCCTCCGACTTCGTCATCCACAGCTCGCCTCAGAGTTTCTAGCTTTCAAGGCCAATCACACTGCGAGCCCTCTCGAAGACTCCGCCGTGCTCGCTGCTCCTGCGTCGCCTGTACCTGCGTGCAAAGCTTCTACATCGAGCACCGCAACCTCGGTCGTGCCTGCCGTTCCCGCGTCGCCTATACTGGCGAGTAAAACTGCTGCGTCGTCCACCGTGGCCACCGTTCCAGCTGTGCGATCATCCGCGGCCTCCGTCGCGCCCTCCAAAACACCTGCTCGTAGGTCACCGGCGCCCTCCTCCTCGTCCTCCGACTCTGACTCGGAGATGGAGGTCGACCTCGCCCCCGCCTCATCGACGGATGGATTTACCCTGGTACAAAAGGGTAAGAAGCGTGCCGCGGAGTCCCGAGCTCCCGCGGCCGCTAAAATTAGCAAAGCCGCGAACGCGTCGCGCCCCCGCCCCCAGACTCCCGTTGCGCCTCCAGCCCGTGCCAGTCCGTCGCCGCGTCCGGTGGCACAAAATAAAACCCAGTCCCCTCCTCCGGTAATCCTTCAAGAGAAGGCAGCTTGGGATCGAGTTTCCCTGGCCCTTAAGGCCAAAAATATCAATTTCACGAATGCCCGTAACCTCGCGAACGGCATCCAAATAAAGGTGCATTCATCTGATGACCATAGGACCCTCACCTCTTACCTCCGTAAGGAGCGTATAAGCTTCCACACTTATACGCTCCAGGAGGAGCGCGAACTCCGCGTTGTAATACGCGGAATCCCTAAAGAGTTAGATGTAGAGCTCGTAAAAGCCGACCTGTTAGAACAAGGCCTACCAGTGAATTCTGTGCACCGTATGCACACCGGTCGCGGTAGGGAGCCATATAATATGGTTCTAGTCGCTCTCCAGCCTACCCCGAGGGAGACCCTACTTAAGCCCGCGCGCCGTGACCCTAAAATCGCGAACTATAACATGGTCAGGAACGACAGGCTCTCTGCCCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCGCTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGATCGTTCTAAGCAGTGATATCGAGGCACTTCTCGGTATGGGGAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATCAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGGCTTGACGCGTTAGTCGATGATCTCGCCTTCGATATCGTCGCTCCGTTAACCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAACCTGGACTCTACCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCTTAACATCACACATCACCTCGACATTAGATAGGTCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATACGCGCCTACGACAGATATCCTACCGCGGAAAATCGTATTCGAATGCGTGCCCTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTTGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTAGCCTCCTTGCCACCCTCGGATGCGTTACCACCCGTTACCCCGATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCTAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGTTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAGCTGTATGAGCGTCTGCTCTACAAGCGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTCATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAACGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGCCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCTGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCAATTCGGAAATACATGAAGTCAGCGTCGGAACGATACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTAGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTTGCATTAGATGCCTTCAGCTCTAATACTAGGGGCAGGCTTAGGGACCCCGGTAACCGTACTCGTCGAACTCGACAAAGAGGTCGACGTGCAACCTAA

Protein

MDAVFAEFLRLRHPQLASEFLAFKANHTASPLEDSAVLAAPASPVPACKASTSSTATSVVPAVPASPILASKTAASSTVATVPAVRSSAASVAPSKTPARRSPAPSSSSSDSDSEMEVDLAPASSTDGFTLVQKGKKRAAESRAPAAAKISKAANASRPRPQTPVAPPARASPSPRPVAQNKTQSPPPVILQEKAAWDRVSLALKAKNINFTNARNLANGIQIKVHSSDDHRTLTSYLRKERISFHTYTLQEERELRVVIRGIPKELDVELVKADLLEQGLPVNSVHRMHTGRGREPYNMVLVALQPTPRETLLKPARRDPKIANYNMVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTLRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFNLDSTPSPQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDDIRELLRAKNASIRAYDRYPTAENRIRMRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARTLKSDTVVTMPPLVGPSGRLAAFDDDEKAELLADTLASLPPSDALPPVTPMEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSALSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSNTRGRLRDPGNRTRRTRQRGRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon X-element

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139W8G9   A0A139WA11   V5GNF3   X1WLB2   X1WNI2   J9LC21   X1WZH0   A0A2J7R7D0   A0A224X6Q4   A0A2J7Q6J2   A0A2J7PU96   A0A2J7QR37   A0A2J7PBY3   J9LFC9   A0A2J7QY69   A0A2S2Q383   A0A224X6T4   A0A2M4BD67   A0A2J7QB68   A0A2M4BDV6   A0A2M4CV52   A0A224XI99   A0A069DZL8   A0A2M4CV42   A0A087UGF5   A0A2J7PVX3   A0A224X6U5   A0A2M4BD83   A0A2S2NH02   A0A224X6S1   Q07995   Q9NBX4   A0A2S2R9D4   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A1Y1KFR3   A0A224X746   A0A224XJI0   A0A3N5Z7I3   A0A224XIB0   A0A2H8TKI9   A0A2S2NPG3   A0A023F069   A0A224X6W2   A0A2S2P3X8   A0A2J7Q0S7   A0A2S2P698  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
26334808    8387152    11405632    30086797    25474469   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005359    JAB63107.1    ABLF02042518    ABLF02057746    ABLF02008153    ABLF02008462    ABLF02008464    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    ABLF02034467    NEVH01006736    PNF36716.1    GFTR01008279    JAW08147.1    NEVH01017470    PNF24199.1    NEVH01021205    PNF19912.1    NEVH01011985    PNF31054.1    NEVH01027074    PNF13841.1    ABLF02023911    NEVH01009134    PNF33528.1    GGMS01002992    MBY72195.1    GFTR01008261    JAW08165.1    GGFJ01001858    MBW50999.1    NEVH01016302    PNF25823.1    GGFJ01001857    MBW50998.1    GGFL01004957    MBW69135.1    GFTR01008256    JAW08170.1    GBGD01000415    JAC88474.1    GGFL01005012    MBW69190.1    KK119692    KFM76444.1    NEVH01020940    PNF20481.1    GFTR01008251    JAW08175.1    GGFJ01001822    MBW50963.1    GGMR01003864    MBY16483.1    GFTR01008271    JAW08155.1    S59870    AAB26437.2    AF237761    AAF81411.1    GGMS01017365    MBY86568.1    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    GEZM01084969    JAV60363.1    GFTR01008151    JAW08275.1    GFTR01008257    JAW08169.1    RPOV01000134    RPJ78669.1    GFTR01008246    JAW08180.1    GFXV01002840    MBW14645.1    GGMR01006408    MBY19027.1    GBBI01003810    JAC14902.1    GFTR01008260    JAW08166.1    GGMR01011511    MBY24130.1    NEVH01019963    PNF22185.1    GGMR01012305    MBY24924.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000054359   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q9NBX4   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139W8G9   A0A139WA11   V5GNF3   X1WLB2   X1WNI2   J9LC21   X1WZH0   A0A2J7R7D0   A0A224X6Q4   A0A2J7Q6J2   A0A2J7PU96   A0A2J7QR37   A0A2J7PBY3   J9LFC9   A0A2J7QY69   A0A2S2Q383   A0A224X6T4   A0A2M4BD67   A0A2J7QB68   A0A2M4BDV6   A0A2M4CV52   A0A224XI99   A0A069DZL8   A0A2M4CV42   A0A087UGF5   A0A2J7PVX3   A0A224X6U5   A0A2M4BD83   A0A2S2NH02   A0A224X6S1   Q07995   Q9NBX4   A0A2S2R9D4   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A1Y1KFR3   A0A224X746   A0A224XJI0   A0A3N5Z7I3   A0A224XIB0   A0A2H8TKI9   A0A2S2NPG3   A0A023F069   A0A224X6W2   A0A2S2P3X8   A0A2J7Q0S7   A0A2S2P698  

PDB

6AR3     E-value=0.0530684,     Score=90

KEGG

105841788    no KO assigned | (RefSeq) predicted GPI-anchored protein 58

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

1200

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.11811000000001

Exp number, first 60 AAs:

3e-05

Total prob of N-in:

0.00008

outside

1  -  1200

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

24.890255

CSRT

0

Interpretation

Uncertain