Gene

KWMTBOMO01855

Pre Gene Modal

BGIBMGA006184

Annotation

PREDICTED:_protein_ultraspiracle_homolog_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr4(+):6443933-6487147      View in EpiBrowser

Full name

Protein ultraspiracle homolog      

Alternative Name

BmCF1
Nuclear receptor subfamily 2 group B member 4
RXR type hormone receptor CF1

Transcription factor

RXR-like

Location in the cell

Mitochondrial   Reliability : 1.593 Nuclear   Reliability : 1.457

CDS

ATGACGCCTAGCCCACAGCAGCAGCAGCAGATGGTGCCGTCTACACAGCATTCGAATTTCCTGCAGCCAATGGCTACACCTTCAACCACACCCAATGTTGAACTCGATATACAATGGCTGAACATAGAGTCAGGGTTTATGTCGCCTATGTCACCGCCCGAAATGAAGCCAGATACGGCGATGCTCGACGGTTTCCGAGACGACTCGACGCCGCCCCCTCCCTTCAAGAATTATCCCCCTAACCATCCCTTGAGCGGCTCAAAACATCTATGCTCCATATGTGGCGACAGAGCCTCGGGCAAACATTACGGAGTATACAGTTGTGAAGGCTGCAAAGGGTTCTTCAAGAGGACAGTCAGGAAGGATCTCACATACGCGTGCCGGGAGGACAAGAATTGTATAATAGATAAACGCCAGCGGAATCGTTGCCAGTACTGCCGATACCAGAAGTGTCTCGCTTGCGGCATGAAGAGGGAGGCTGTGCAAGAGGAGAGACAGCGAGCCGCGAGGGGTACAGAAGACGCTCATCCCAGCAGCTCTGTACAGGAGCTATCGATCGAGCGGCTGCTGGAATTGGAGGCGTTAGTTGCGGATTCAGCTGAGGAGTTACAGATCCTACGCGTCGGTCCCGAAAGCGGCGTGCCGGCCAAGTACCGAGCTCCCGTTTCGAGTCTTTGTCAAATAGGCAACAAACAGATAGCCGCTCTCATTGTTTGGGCGCGTGACATTCCACACTTCGGGCAGCTAGAAATCGACGATCAGATCCTTCTAATCAAGGGCTCCTGGAACGAACTGCTGCTGTTCGCTATCGCATGGCGGTCTATGGAGTTCCTCAATGATGAACGAGAGAACGTAGACTCGCGGAATACGGCGCCGCCTCAACTCATTTGTTTAATGCCAGGCATGACGCTGCACCGCAACTCCGCGCTGCAGGCCGGCGTGGGGCAGATCTTCGACCGCGTGCTCTCCGAGCTGTCGCTCAAGATGCGCTCCCTCCGCATGGACCAGGCCGAGTACGTCGCGCTCAAGGCCATCATACTCCTCAATCCTGACGTAAAAGGATTGAAGAATAAACAAGAAGTGGACGTTCTTCGAGAAAAGATGTTCTTATGCCTGGACGAGTACTGCCGGCGCTCGCGCGGCGGGGAGGAGGGTCGGTTCGCGGCGCTGCTGCTGCGGCTGCCGGCGCTGCGCTCCATCTCGCTCAAGAGCTTCGAGCACCTCTACCTGTTCCACCTCGTGGCCGAGGGCAGCGTGAGCTCGTACATCCGCGACGCGCTCTGCAACCACGCGCCGCCCATCGACACCAACATCATGTAG

Protein

MTPSPQQQQQMVPSTQHSNFLQPMATPSTTPNVELDIQWLNIESGFMSPMSPPEMKPDTAMLDGFRDDSTPPPPFKNYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACREDKNCIIDKRQRNRCQYCRYQKCLACGMKREAVQEERQRAARGTEDAHPSSSVQELSIERLLELEALVADSAEELQILRVGPESGVPAKYRAPVSSLCQIGNKQIAALIVWARDIPHFGQLEIDDQILLIKGSWNELLLFAIAWRSMEFLNDERENVDSRNTAPPQLICLMPGMTLHRNSALQAGVGQIFDRVLSELSLKMRSLRMDQAEYVALKAIILLNPDVKGLKNKQEVDVLREKMFLCLDEYCRRSRGGEEGRFAALLLRLPALRSISLKSFEHLYLFHLVAEGSVSSYIRDALCNHAPPIDTNIM

Description

Receptor for ecdysone. May be an important modulator of insect metamorphosis (By similarity).

Subunit

Heterodimer of USP and ECR.
Heterodimer of USP and ECR. Only the heterodimer is capable of high-affinity binding to ecdysone (By similarity).

Similarity

Belongs to the nuclear hormone receptor family. NR2 subfamily.
Belongs to the nuclear hormone receptor family.

Keywords

Complete proteome   DNA-binding   Metal-binding   Nucleus   Receptor   Reference proteome   Transcription   Transcription regulation   Zinc   Zinc-finger  

Feature

chain  Protein ultraspiracle homolog

Uniprot

P49700   P54779   A0A2W1BFV9   A0A1V0J8W3   M4IQQ9   K7WYJ0   + More
S5YEA6   A9UEF7   A0A2H4Z8R4   E3UJZ6   O76202   A0A2A4K9Z3   A0A194PKF8   B9UCQ5   B2ZCQ5   K7WLB9   A0A2A4K9M0   A0A0M5KTU5   S5XLP8   Q8I1M8   I3RQC0   Q6IVK1   G9M5R1   G5CV12   A0A212F7B4   A0A194R7V9   A0A0L7LGU6   Q1AHP6   A0A1D6YNX1   A0A1L8DHL9   U5EZR1   A0A1L8DHH7   A0A0K8TPF2   A0A336LQ69   A0A336N026   K0BY27   A0A336N4B2   Q9GSG7   A0A1S4EVT0   Q9GSG8   Q0IGE0   A0A1S4EVR8   A0A182HDC9   A0A023EU70   B0X9K6   A0A1Q3FWN1   A0A084VW20   A0A0A1WR56   A0A182MKL1   A0A182RT62   A0A182VRF8   A0A182UL84   A0A182XW12   A0A182PE19   Q9U3Y3   T1DL21   W8C145   F5HN02   E0Z5Q8   A0A182HZX0   A0A182XGF6   F5HN03   A0A0K8VTG0   A0A034VVC4   A0A182LQZ6   A0A182V3C6   A0A182N6B8   A0A182QE69   A0A182IQI7   A0A2M4AKG3   A0A2M4AKL7   A0A2M4AJP8   A0A2M4AJP7   A0A182F802   A0A2M4AJT5   A0A2M4CWG7   W5JAL7   A0A1A9W9F4   A0A1A9XH09   A0A1B0FMJ8   A0A1A9VRP2   A0A1A9Z1M9   A0A1B0AND1   K4MJU9   A0A1I8NWH7   T1P9L7   K4MV69   Q962I5   A0A0L0BR06   A0A1J1HRR1   T1GBH8  

Pubmed

8176738    9013254    28756777    23523827    22044719    9581288    + More
26354079    26325588    12459199    15796748    22118469    26227816    16756554    26369729    8892313    9765285    17510324    26483478    24945155    24438588    25830018    25244985    10644973    24495485    12364791    14747013    17210077    25348373    20966253    20920257    23761445    23039844    25315136    11378412    26108605   

EMBL

U06073    U44837    KZ150176    PZC72564.1    KY411160    ARD05166.1    + More
JQ731606    AGA17964.1    JX680324    AFX60116.1    KC953864    AGT02382.1    EU180022    JQ730733    ABX79144.1    AFK27932.1    KY488556    AUF71655.1    HM445735    ADO64596.1    AF016368    NWSH01000026    PCG80603.1    KQ459601    KPI93926.1    EU526832    ACD74808.1    EU642475    ACD39740.1    JX680325    AFX60117.1    PCG80604.1    KT343806    ALD83751.1    KC953863    AGT02381.1    AB081840    BAC53670.1    JQ730734    AFK27933.1    AY619987    AAT44330.1    AB568470    BAL41655.1    GU222670    JN410831    ADA61199.1    AEP25407.1    AGBW02009889    OWR49634.1    KQ460855    KPJ11956.1    JTDY01001136    KOB74773.1    DQ083513    AAZ38141.1    KR815909    ANF34832.1    GFDF01008250    JAV05834.1    GANO01000320    JAB59551.1    GFDF01008249    JAV05835.1    GDAI01001582    JAI16021.1    UFQS01000101    UFQT01000101    SSW99595.1    SSX19975.1    UFQS01005117    UFQT01005117    SSX16712.1    SSX35904.1    GQ427084    AFT63499.1    UFQS01005149    UFQT01005149    SSX16732.1    SSX35923.1    AF305214    CH477192    AAG24887.1    EJY57333.1    AF305213    AAG24886.1    EAT48598.1    JXUM01001635    JXUM01001636    KQ560125    KXJ84343.1    GAPW01001121    JAC12477.1    DS232541    EDS43175.1    GFDL01003169    JAV31876.1    ATLV01017380    KE525164    KFB42164.1    GBXI01013384    GBXI01002981    JAD00908.1    JAD11311.1    AXCM01005402    AF210734    AAF19033.1    GAMD01000661    JAB00930.1    GAMC01001143    JAC05413.1    AAAB01008987    EGK97384.1    HM195185    ADM64635.1    APCN01002017    EAA01003.6    EGK97383.1    EGK97385.1    GDHF01010171    JAI42143.1    GAKP01013459    JAC45493.1    AXCN02000281    AXCN02000282    GGFK01007952    MBW41273.1    GGFK01007951    MBW41272.1    GGFK01007688    MBW41009.1    GGFK01007689    MBW41010.1    GGFK01007686    MBW41007.1    GGFL01005504    MBW69682.1    ADMH02002036    ETN59829.1    CCAG010001067    JXJN01000796    JQ679100    AFV25497.1    KA645422    AFP60051.1    JQ679104    AFV25501.1    AY007213    AAG01569.1    JRES01001496    KNC22467.1    CVRI01000015    CRK90076.1    CAQQ02103930   

Proteomes

UP000005204    UP000218220    UP000053268    UP000007151    UP000053240    UP000037510    + More
UP000008820    UP000069940    UP000249989    UP000002320    UP000030765    UP000075883    UP000075900    UP000075920    UP000075902    UP000076408    UP000075885    UP000007062    UP000075840    UP000076407    UP000075882    UP000075903    UP000075884    UP000075886    UP000075880    UP000069272    UP000000673    UP000091820    UP000092443    UP000092444    UP000078200    UP000092445    UP000092460    UP000095300    UP000095301    UP000037069    UP000183832    UP000015102   

PRIDE

P49700    P54779   

Pfam

PF00105   zf-C4        + More
PF00104   Hormone_recep

Interpro

IPR035500   NHR-like_dom_sf        + More
IPR001723   Nuclear_hrmn_rcpt       
IPR013088   Znf_NHR/GATA       
IPR000536   Nucl_hrmn_rcpt_lig-bd       
IPR000003   Retinoid-X_rcpt/HNF4       
IPR001628   Znf_hrmn_rcpt       

SUPFAM

SSF48508   SSF48508       

Gene 3D

1.10.565.10     3.30.50.10    

ProteinModelPortal

P49700   P54779   A0A2W1BFV9   A0A1V0J8W3   M4IQQ9   K7WYJ0   + More
S5YEA6   A9UEF7   A0A2H4Z8R4   E3UJZ6   O76202   A0A2A4K9Z3   A0A194PKF8   B9UCQ5   B2ZCQ5   K7WLB9   A0A2A4K9M0   A0A0M5KTU5   S5XLP8   Q8I1M8   I3RQC0   Q6IVK1   G9M5R1   G5CV12   A0A212F7B4   A0A194R7V9   A0A0L7LGU6   Q1AHP6   A0A1D6YNX1   A0A1L8DHL9   U5EZR1   A0A1L8DHH7   A0A0K8TPF2   A0A336LQ69   A0A336N026   K0BY27   A0A336N4B2   Q9GSG7   A0A1S4EVT0   Q9GSG8   Q0IGE0   A0A1S4EVR8   A0A182HDC9   A0A023EU70   B0X9K6   A0A1Q3FWN1   A0A084VW20   A0A0A1WR56   A0A182MKL1   A0A182RT62   A0A182VRF8   A0A182UL84   A0A182XW12   A0A182PE19   Q9U3Y3   T1DL21   W8C145   F5HN02   E0Z5Q8   A0A182HZX0   A0A182XGF6   F5HN03   A0A0K8VTG0   A0A034VVC4   A0A182LQZ6   A0A182V3C6   A0A182N6B8   A0A182QE69   A0A182IQI7   A0A2M4AKG3   A0A2M4AKL7   A0A2M4AJP8   A0A2M4AJP7   A0A182F802   A0A2M4AJT5   A0A2M4CWG7   W5JAL7   A0A1A9W9F4   A0A1A9XH09   A0A1B0FMJ8   A0A1A9VRP2   A0A1A9Z1M9   A0A1B0AND1   K4MJU9   A0A1I8NWH7   T1P9L7   K4MV69   Q962I5   A0A0L0BR06   A0A1J1HRR1   T1GBH8  

PDB

4UMM     E-value=5.00596e-120,     Score=1104

KEGG

693034    K14030 nuclear receptor subfamily 2 group B member 4 | (RefSeq) USP, BmCF1, BmUSP-2, Cf1, RXRB; RXR

PATHWAY

04214    Apoptosis - fly - Bombyx mori (domestic silkworm)

GO

GO:0008270   GO:0003700   GO:0005634   GO:0003707   GO:0043565   GO:0016021   GO:0006355   GO:0043401   GO:0003677   GO:0004651  

Subcellular location

Nucleus  

Length:

439

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00869

Exp number, first 60 AAs:

0.00022

Total prob of N-in:

0.00960

outside

1  -  439

 

 

Pi

22.216723

Theta

32.027251

Tajima's D

0.175397

CLR

131.11118

CSRT

0.417829108544573

Interpretation

Uncertain