Gene

KWMTBOMO16867  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011844

Annotation

protein_disulfide_isomerase_precursor_[Bombyx_mori]

Location

Bomo_Scaf564(+):776-9695      View in EpiBrowser

Full name

Protein disulfide-isomerase      

Location in the cell

ER   Reliability : 2.628

CDS

ATGGAGATCTTGGAGTTCTTCGGCATGAAGAAGGATGAGGTTCCATCTGCCCGTCTGATCGCCCTTGAACAAGACATGGCCAAATACAAGCCCAGCAGTAATGAGCTGTCGCCTAACGCTATTGAGGAATTCGTTCAATCGTTCTTCGACGGCACCCTGAAGCAGCATCTGCTGAGCGAGGACCTGCCCTCGGACTGGGCCGCCAAACCCGTCAAAGTGCTCGTCGCCGCCAACTTCGACGAAGTCGTCTTCGACACAACTAAGAAGGTCCTCGTCGAATTCTACGCTCCTTGGTGCGGCCACTGCAAACAGCTGGTCCCTATCTACGACAAGCTCGGCGAGCACTTTGAGAACGACGATGACGTCATCATTGCCAAAATCGACGCCACCGCCAACGAACTGGAACACACCAAGATCACGTCCTTCCCAACGATCAAACTTTACAGCAAGGACAACCAGGTCCACGACTACAACGGCGAGAGGACACTGGCCGGCCTCACCAAGTTCGTTGAGACCGACGGTGAAGGCGCCGAGCCAGGACCTTCTGTGACCGAATTCGAAGAGGAGGAAGATGAATTCGTTCAATCGTTCTTCGACGGCACCCTGAAGCAGCATCTGCTGAGCGAGGACCTGCCCTCGGACTGGGCCGCCAAACCCGTCAAAGTGCTCGTCGCCGCCAACTTCGACGAAGTCGTCTTCGACACAACTAAGAAGGTCCTCGTCGAATTCTACGCTCCTTGGTAA

Protein

MEILEFFGMKKDEVPSARLIALEQDMAKYKPSSNELSPNAIEEFVQSFFDGTLKQHLLSEDLPSDWAAKPVKVLVAANFDEVVFDTTKKVLVEFYAPWCGHCKQLVPIYDKLGEHFENDDDVIIAKIDATANELEHTKITSFPTIKLYSKDNQVHDYNGERTLAGLTKFVETDGEGAEPGPSVTEFEEEEDEFVQSFFDGTLKQHLLSEDLPSDWAAKPVKVLVAANFDEVVFDTTKKVLVEFYAPW

Catalytic Activity

Catalyzes the rearrangement of -S-S- bonds in proteins.

Similarity

Belongs to the protein disulfide isomerase family.

Feature

chain  Protein disulfide-isomerase

Uniprot

H9JQN8   Q9GPH2   A0A0K8STM5   A0A437BK29   I4DIQ3   A0A2H1VU96   + More
A0A0U1VTU3   A0A2A4J7L8   I4DLY7   S4NP33   G9D554   A0A212FP73   A0A1B6G600   U5EXV6   A0A1L8DUB3   A0A1L8DUB0   A0A1B6IVK8   A0A1L8DUD1   V5GZ61   U5EV80   A0A2J7R328   A0A034VPG6   A0A1B6KDW2   A0A146L261   A0A0P5SMK4   A0A0P4WI78   E0VGK5   A0A0N8EAP0   C0JBY4   A0A0P5CNW6   D6WHD6   A0A0P4YEJ8   W8BHI2   A0A1J1I589   A0A1B6DM68   A0A0A9YM47   A0A034VQH7   G9JKY3   A0A0K8TWH4   A0A0P4VT63   A0A0P5JGG6   A0A0P5K4B5   A0A0P5JCL2   E9FUV9   A0A0N8CDX5   A0A0P5QZX1   A0A0P5PBS6   A0A0P5GM21   A0A0P5N6U9   A0A0P5USZ5   A0A067RBI3   A0A0P5VYZ6   A0A0P5JPM2   A0A0P6D8Q6   A0A0P5EXC3   A0A0P5NL58   A0A0P5U7Q0   A0A0P5JJB3   A0A226ECT4   A0A0P5NER3   A0A0P5ENJ2   A0A0P5I7C0   A0A0A1XJL3   A0A2I9LPF6   A0A0N8B9Q8   R4WQK3   A0A0P6HG07   A0A0P5E0R1   A0A0P6DCF2   A0A0P5JJZ6   A0A0P4WUW3   A0A0P5JTS0   A0A3Q0J6F3  

EC Number

5.3.4.1

Pubmed

19121390    11892983    22651552    26354079    23622113    21967427    + More
22118469    25348373    26823975    20566863    18362917    19820115    24495485    25401762    27129103    21292972    24845553    25830018    29248469    23691247   

EMBL

BABH01012177    AF325211    AAG45936.1    GBRD01009292    JAG56529.1    RSAL01000043    + More
RVE50731.1    AK401171    KQ459590    BAM17793.1    KPI97250.1    ODYU01004447    SOQ44326.1    JX183988    AGF69546.1    NWSH01002655    PCG67756.1    AK402305    BAM18927.1    GAIX01012014    JAA80546.1    JF777457    AEU11802.1    AGBW02003612    OWR55527.1    GECZ01011903    JAS57866.1    GANO01000727    JAB59144.1    GFDF01004052    JAV10032.1    GFDF01004053    JAV10031.1    GECU01021031    GECU01016836    GECU01003704    JAS86675.1    JAS90870.1    JAT04003.1    GFDF01004054    JAV10030.1    GALX01002703    JAB65763.1    GANO01001143    JAB58728.1    NEVH01007823    PNF35251.1    GAKP01014588    JAC44364.1    GEBQ01030325    JAT09652.1    GDHC01016151    JAQ02478.1    GDIP01137885    JAL65829.1    GDRN01036013    JAI67374.1    DS235148    EEB12511.1    GDIQ01045348    JAN49389.1    FJ179395    ACN89260.1    GDIP01167789    JAJ55613.1    KQ971321    EFA00647.1    GDIP01228674    JAI94727.1    GAMC01017431    GAMC01017428    JAB89124.1    CVRI01000042    CRK95503.1    GEDC01010527    JAS26771.1    GBHO01009502    GBHO01009500    GBRD01012827    JAG34102.1    JAG34104.1    JAG52999.1    GAKP01014585    JAC44367.1    JN863961    AEW66914.1    GDHF01033678    JAI18636.1    GDKW01002455    JAI54140.1    GDIQ01200294    JAK51431.1    GDIQ01189801    JAK61924.1    GDIQ01200293    JAK51432.1    GL732525    EFX88851.1    GDIP01141247    JAL62467.1    GDIQ01109876    JAL41850.1    GDIQ01130874    JAL20852.1    GDIQ01267948    GDIQ01245936    GDIQ01170947    JAK05789.1    GDIQ01146317    JAL05409.1    GDIP01168587    GDIP01149449    GDIP01112092    GDIP01043389    JAL91622.1    KK852567    KDR21216.1    GDIP01142334    GDIP01094099    JAM09616.1    GDIQ01200295    JAK51430.1    GDIQ01080984    JAN13753.1    GDIQ01265663    JAJ86061.1    GDIQ01143622    JAL08104.1    GDIP01133897    JAL69817.1    GDIQ01198998    JAK52727.1    LNIX01000004    OXA55402.1    GDIQ01143565    JAL08161.1    GDIQ01267549    JAJ84175.1    GDIQ01217681    JAK34044.1    GBXI01002738    JAD11554.1    GFWZ01000275    MBW20265.1    GDIQ01198995    JAK52730.1    AK416967    BAN20182.1    GDIQ01029114    JAN65623.1    GDIP01148149    JAJ75253.1    GDIQ01080983    JAN13754.1    GDIQ01198996    JAK52729.1    GDIP01252819    JAI70582.1    GDIQ01198997    JAK52728.1   

Proteomes

UP000005204    UP000283053    UP000053268    UP000218220    UP000007151    UP000235965    + More
UP000009046    UP000007266    UP000183832    UP000000305    UP000027135    UP000198287    UP000079169   

PRIDE

H9JQN8    Q9GPH2    C0JBY4   

Pfam

PF00085   Thioredoxin

Interpro

IPR036249   Thioredoxin-like_sf        + More
IPR017937   Thioredoxin_CS       
IPR005792   Prot_disulphide_isomerase       
IPR013766   Thioredoxin_domain       
IPR005788   Disulphide_isomerase       

SUPFAM

SSF52833   SSF52833       

ProteinModelPortal

H9JQN8   Q9GPH2   A0A0K8STM5   A0A437BK29   I4DIQ3   A0A2H1VU96   + More
A0A0U1VTU3   A0A2A4J7L8   I4DLY7   S4NP33   G9D554   A0A212FP73   A0A1B6G600   U5EXV6   A0A1L8DUB3   A0A1L8DUB0   A0A1B6IVK8   A0A1L8DUD1   V5GZ61   U5EV80   A0A2J7R328   A0A034VPG6   A0A1B6KDW2   A0A146L261   A0A0P5SMK4   A0A0P4WI78   E0VGK5   A0A0N8EAP0   C0JBY4   A0A0P5CNW6   D6WHD6   A0A0P4YEJ8   W8BHI2   A0A1J1I589   A0A1B6DM68   A0A0A9YM47   A0A034VQH7   G9JKY3   A0A0K8TWH4   A0A0P4VT63   A0A0P5JGG6   A0A0P5K4B5   A0A0P5JCL2   E9FUV9   A0A0N8CDX5   A0A0P5QZX1   A0A0P5PBS6   A0A0P5GM21   A0A0P5N6U9   A0A0P5USZ5   A0A067RBI3   A0A0P5VYZ6   A0A0P5JPM2   A0A0P6D8Q6   A0A0P5EXC3   A0A0P5NL58   A0A0P5U7Q0   A0A0P5JJB3   A0A226ECT4   A0A0P5NER3   A0A0P5ENJ2   A0A0P5I7C0   A0A0A1XJL3   A0A2I9LPF6   A0A0N8B9Q8   R4WQK3   A0A0P6HG07   A0A0P5E0R1   A0A0P6DCF2   A0A0P5JJZ6   A0A0P4WUW3   A0A0P5JTS0   A0A3Q0J6F3  

PDB

4EL1     E-value=5.68473e-56,     Score=548

KEGG

692673    K09580 protein disulfide-isomerase A1 [EC:5.3.4.1] | (RefSeq) Pdi; protein disulfide isomerase

PATHWAY

04141    Protein processing in endoplasmic reticulum - Bombyx mori (domestic silkworm)

GO

GO:0005623   GO:0045454   GO:0003756   GO:0016853   GO:0004579   GO:0005783   GO:0006457   GO:0034976   GO:0016020   GO:0004888   GO:0007166   GO:0016773   GO:0006096   GO:0006281   GO:0006259  

Length:

247

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00836

outside

1  -  247

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0

CSRT

0

Interpretation

Uncertain