Gene

KWMTBOMO16790

Annotation

non-LTR_retrotransposon_R1Bmks_ORF2_protein_[Bombyx_mori]

Location

Bomo_Scaf237(+):716-5066      View in EpiBrowser

Full name

Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1      

Alternative Name

Retrovirus-related Pol polyprotein from type I retrotransposable element R1

Location in the cell

Nuclear   Reliability : 0.987

CDS

ATGTCGGTGGCGACGGCGGCATCTAAGCTCAATAAGTCGGAGGTCAATCTAATCTCTGAACTCGGTCGCGATATCCTGGCCGTAGTTGGGGCCCTCGGGATCCAGCTCTCTGATAAGGAGCTGGTGGTCGAAAGGCTCCGCTCGGCAGAGGCCTCTGCACGGCGTGACTCCGTGGCGCCTTCGATGGCTGCTGGTGCGGCGGCCGGGTCTGGGACTGGGCCTGCGACCTTCGCCACTGTCCTCAGGACGGGCCCTGGTGGGGTCCCGAGGTCCATTGGGGCCTCTCAGGGGCCTTCCTTGGCATTCTACCCGTCCGAGGGCAATGCGGAACTGAAGACAGCTGAGGACACAAAGAAAGAGGAAGGTTGGGAATGCGGGGGTAGTGGTGCAGACCACGTCCCCGCGGCCGCAGTCAAGCTTAGAAATGCTGCCCCGCCATCACTGAGAGTCACCGAACCCAGGCGCCGACAGCCCTTAGTAGCTGTCAATGGCGTGGAGGGCGACCCCTCCTTCGAGGAGGTAATCGAGTGCCTGGCTAGCCAGAACCTCGACCCGGAGGAGTGGCCCCTCACTAGGGTACGAGCGGAGCTCACGGGGGCGTTCAAAAAGGGGAGGCGACAATCCAACAACACTACTGTGGTGTTTAACGCCTCCCCTCGCATCAGGGACGCCCTCGTGAAGATTGGCAGAGTGTATGTGGGGTCGAGTATGGATATTAGGCCCCGACTTCGTATTGGCCAAATCAATCTGGGTGGTGCAGAGGATGCGACGAGGGAGCTACCCTCCATTGCACGGGATCTCGGCCTGGATATTGTTCTTGTACAGGAACAATATTCCATGGTCGGGTTCCTAGCCCAATGTGGAGCACACCCCAAGGCGGGTGTGTATATCCGCAATAGGGTGCTCCCCTGCGCGGTTCTGCACCACCTTAGCAGCACACATATAACGGTAGTGCACATTGGGGGGTGGGACTTATATATGGTGTCTGCGTACTTCCAGTATAGTGACCCTATTGACCCATACCTGCACCGGCTCGGGAATATTCTTGACCGGCTGCGGGGGGCTCGGGTCGTTATCTGCGCAGACACTAATGCCCACTCGCCATTGTGGCACTCGCTGCCCAGGCACTACGTCGGTCGGGGTCAGGAAGTGGCTGACCGCCGCGCCAAGATGGAGGATTTCATTGGGGCGAGGCGGTTGGTCGTCCATAACGCGGATGGCCACCTGCCGACCTTCAGTACGGCGAACGGAGAATCTTATGTCGATGTCACGCTGTCTACGCGGGGAGTACGCGTGTCTGAATGGCGTGTAACTAATGAATCATCGAGCGATCACCGGCTCATTGTGTTTGGGGTGGGGGGCGGTACAACAGGGGAGCGGGACGAGGACGAGGAGGCGCGGAGCGATTTGAGGCCGGGCGAGCCGTGCGCACTGCGTCGGTACCGGGACCGTGGGGTGGATTGGGACCTCTTCAGATCGCGTATCCACGAGCGAATGGGGAGTCTGGACCTCGAGGAACCTGTGGCTGCCCTTTGCGAAAAATTTACCGGGGTTATAACTCGCACAGCTGAAGAATGCTTAGGATCACTGAAAGCAGATAGAACTGACAGGGGTTATGAGTGGTGGACCCCAGTACTCGATAAGCTTAGGGTAGCCCAGGGTAGGGCCAGGCGTCGATGGCAAAAGGCCCGCCGAACGGGGGGTGAGGAAGAGGAGCAGTCTGGGAGAGTCTTCCGCGACCGCAGGCGCGAGTATCGAAGAGCGATGCATGACGCTGAGACCGCCTTTTACCGGGAGATCGCTGAAGGGGGAAACCGTGACCCGTGGGGACTAGCGTATCGGACGGCGAGTGGTAGGCGACGCGCACCAACTAATGTGGTTAACGGGGTGGAGTATGCGGGGCGGTGCTCGGATGATGTGAGTGGGGCCATGCGCACCTTGATGTGGGCGCTGTGTCCGGATGACTATATGTCTCGGGACACTCCGTACCATGCGCGGGTGCGTATCATGGCCGCGCTCCCCCCATCCGGGCGGGACGCAGACCCGCTGAGCAAAGACTCCCTTCGTGCCATAATTGGCTCACTGAAGAATACCGCACCGGGCATCGACGGTTTAACGGCGCGCATTATCAAAAAGGCACTTCCGGCTGCTGAGGCCGAGTTCGTGGCCGTATACGCACGGTGCGTTGTGGAGGGGACCTTCCCGCCGGTGTGGAAGGATGGCCGCCTACTTGTTCTGCCAAAGGGGAATGGCAGGCCCTTAACGGACCCTAAGGCGTATCGCCCGGTCACCTTGCTGCCGGTCCTGGGAAAGATCTTGGAGAAGGTATTATTGCAGTGTGCTCCTGGCCTCACCCATAGTATTAGTCCGCGCCAGCACGGGTTCTCTCCTGGACGCTCAACGGTGACGGCGCTGCGAACTCTGCTGGACGTGTCGCGCGCCTCGGAGCAGAGGTACGTAATGGCCATATTCTTGGACATCAGTGGAGCTTTCGATAACGCGTGGTGGCCCATGATAATGGTGAAGGCCAAGCGGAACTGTCCGCCCAACATCTATCGGATGCTGACGGACTATTTCCGCGGACGCCGTATTGCCGTTGTCGCGGGGGAATGTGCGGAATGGAAGGTGTCCACGATGGGCTGTCCGCAGGGCTCAGTGCTCGGGCCGACGCTCTGGAACGTTCTGATGGATGACCTGCTCGCCTTGCCGCAGGGGATAGAGGGAACAGAGATGGTCGCCTATGCCGATGACGTGACGGTACTGGTTAGGGGTGACTCACGGGCGCAGCTTGAGAGGAGAGCGCACGCCGTGCTAGGACTCGCAGAGGGGTGGGCGAGCAGGAATAAGCTCGATTTTGCCCCGGCGAAGTCCCGATGCATAATGCTGAGGGGAAAGTTTCAGCGTCCCCCTATAGTCCGGTACGGCAGTCATGTCATTCGGTTCGAGAACCAGGTGACGGTGTTGGGCGTCGTCTTCGACGATTGCCTCTCTTTCGCGCCGCATGCGGCGGCCATTGGCGAGAGGGCGAGCAGGTGCTTCGGCAAGATGTCTAGAGTTTCGGCTTCGGCTTGGGGGCTGCGATATAGGGCTTTGCGTGTCTTGTACATGGGCACTTATGTTACAACCCTTACCTATGCGGCGGCCGTATGGTATTTGCGGGCTGCTGTGCACGTCGTGCGCAGCGTGCTGCTTAGGACGCAGCGCCCGTCGTTGACGCTGCTAACGAAGGCCTACCGTTCGTGCAGCACGGCTGCTTTGCCGGTGTTGGCGGGCGTCCTGCCGGCGGACCTGGAGGTGACTCGTGCTGGACGGAGGATGCGGGAGTGCGAAGGATTGGCGCGGGAGTTGGCGGCGGAGAGACGACGACGGATCGACGGCGATGTCTTGGTAGTTTGGCAGAACAGGTGGGTGTCTGAGGGTAAGGGGAGGGAACTGTACAAGTTCTTTCCCGATGTTGCGGACAGGAAGAAGGCAACGTGGATGGAGCCGGACTATCAGACCTCGCAGATCCTCACGGGTCATGGGATCTTTAATAAGCGGTTGGCGGATATGCGACTGAGGGAGGGGCATGCTTGCGACTGCGGGGCGGTTGAGGAGGATAGGGACCATGTCCTGTGGGAGTGTCCTCTCTATGACGAAATCCGGGGCAGGATGCTCGATGGAATCTCGCGGTCTGAGGTGGGCCCAGTTTACCACGCGGACCTGGTCAGGGACGAGAAAAATTTTCGGCTCTTGCGCGAGTTCGCGCATACATGGCACACGGCGCGCACTGCGCGCGAATCACGAGGACTGCCTGGCGACGAAGAATGTGGGTGA

Protein

MSVATAASKLNKSEVNLISELGRDILAVVGALGIQLSDKELVVERLRSAEASARRDSVAPSMAAGAAAGSGTGPATFATVLRTGPGGVPRSIGASQGPSLAFYPSEGNAELKTAEDTKKEEGWECGGSGADHVPAAAVKLRNAAPPSLRVTEPRRRQPLVAVNGVEGDPSFEEVIECLASQNLDPEEWPLTRVRAELTGAFKKGRRQSNNTTVVFNASPRIRDALVKIGRVYVGSSMDIRPRLRIGQINLGGAEDATRELPSIARDLGLDIVLVQEQYSMVGFLAQCGAHPKAGVYIRNRVLPCAVLHHLSSTHITVVHIGGWDLYMVSAYFQYSDPIDPYLHRLGNILDRLRGARVVICADTNAHSPLWHSLPRHYVGRGQEVADRRAKMEDFIGARRLVVHNADGHLPTFSTANGESYVDVTLSTRGVRVSEWRVTNESSSDHRLIVFGVGGGTTGERDEDEEARSDLRPGEPCALRRYRDRGVDWDLFRSRIHERMGSLDLEEPVAALCEKFTGVITRTAEECLGSLKADRTDRGYEWWTPVLDKLRVAQGRARRRWQKARRTGGEEEEQSGRVFRDRRREYRRAMHDAETAFYREIAEGGNRDPWGLAYRTASGRRRAPTNVVNGVEYAGRCSDDVSGAMRTLMWALCPDDYMSRDTPYHARVRIMAALPPSGRDADPLSKDSLRAIIGSLKNTAPGIDGLTARIIKKALPAAEAEFVAVYARCVVEGTFPPVWKDGRLLVLPKGNGRPLTDPKAYRPVTLLPVLGKILEKVLLQCAPGLTHSISPRQHGFSPGRSTVTALRTLLDVSRASEQRYVMAIFLDISGAFDNAWWPMIMVKAKRNCPPNIYRMLTDYFRGRRIAVVAGECAEWKVSTMGCPQGSVLGPTLWNVLMDDLLALPQGIEGTEMVAYADDVTVLVRGDSRAQLERRAHAVLGLAEGWASRNKLDFAPAKSRCIMLRGKFQRPPIVRYGSHVIRFENQVTVLGVVFDDCLSFAPHAAAIGERASRCFGKMSRVSASAWGLRYRALRVLYMGTYVTTLTYAAAVWYLRAAVHVVRSVLLRTQRPSLTLLTKAYRSCSTAALPVLAGVLPADLEVTRAGRRMRECEGLARELAAERRRRIDGDVLVVWQNRWVSEGKGRELYKFFPDVADRKKATWMEPDYQTSQILTGHGIFNKRLADMRLREGHACDCGAVEEDRDHVLWECPLYDEIRGRMLDGISRSEVGPVYHADLVRDEKNFRLLREFAHTWHTARTARESRGLPGDEECG

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Keywords

Endonuclease   Hydrolase   Nuclease   Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1

Uniprot

Q5NTZ0   Q7M4J4   V9H050   A0A1B6DRM7   A0A1B6E1N0   A0A023EYP7   + More
A0A224XAL8   K7JAI1   A0A0J7KTH2   J9KMZ9   J9LPJ1   K7JMI9   J9M9N3   X1XHQ0   A0A224X653   J9MA04   J9L798   J9K5I1   J9LPX1   J9LMF6   J9M8T8   J9KPX6   J9L0V3   J9M4Z2   J9LNF5   Q03277   J9LES5   X1WL18   J9K370   X1WUQ0   J9LPX0   J9M2E8   J9LVC2   J9KVB7   J9KRH3   J9LCW5   J9JY36   J9KPC7   A0A087UHT1   J9K2L0   Q9BLI5   J9KPE5   J9KA38   A0A139W914   J9LFF7   A0A142LX43   X1WVB5   Q868T0   A0A0K1IK14   A0A2M4CS98   A0A0K8VPH1   A0A2M4BBV9   A0A2M4BC01   A0A142LX37  

Pubmed

15814816    2447482    17537809    30299944    25474469    20075255    + More
8383793    11319268    18362917    19820115    25527032    12644555   

EMBL

AB182560    BAD82946.1    M19755    AAC13649.1    GEDC01008950    JAS28348.1    + More
GEDC01005462    JAS31836.1    GBBI01004973    JAC13739.1    GFTR01008452    JAW07974.1    AAZX01006426    LBMM01003366    KMQ93606.1    ABLF02039177    ABLF02012872    ABLF02012873    ABLF02012874    ABLF02012875    ABLF02042485    AAZX01008070    ABLF02003402    ABLF02025552    ABLF02031460    ABLF02044302    ABLF02059589    ABLF02065568    ABLF02066832    ABLF02066838    ABLF02010931    GFTR01008469    JAW07957.1    ABLF02008888    ABLF02016960    ABLF02032572    ABLF02007045    ABLF02027069    ABLF02027071    ABLF02012124    ABLF02016436    ABLF02007471    ABLF02007472    ABLF02019936    ABLF02057951    ABLF02012458    ABLF02012459    ABLF02010919    ABLF02010923    ABLF02006133    L00945    ABLF02008889    ABLF02041820    ABLF02010037    ABLF02010039    ABLF02066755    ABLF02008887    ABLF02020087    ABLF02012457    ABLF02020044    ABLF02004774    ABLF02008516    ABLF02041501    ABLF02022279    ABLF02020082    ABLF02020086    ABLF02020092    ABLF02010929    ABLF02019664    ABLF02034348    KK119855    KFM76920.1    ABLF02004512    ABLF02004513    ABLF02046624    ABLF02049075    ABLF02059998    ABLF02065990    AB046668    BAB21511.1    ABLF02008515    ABLF02013103    ABLF02013105    ABLF02013107    ABLF02061460    ABLF02004773    KQ972822    KXZ75771.1    ABLF02003498    ABLF02003499    ABLF02003500    ABLF02014855    ABLF02016356    KU543682    AMS38369.1    ABLF02007851    ABLF02016357    ABLF02064424    AB090812    BAC57900.1    KP771712    AKU04650.1    GGFL01004044    MBW68222.1    GDHF01029467    GDHF01011533    JAI22847.1    JAI40781.1    GGFJ01001369    MBW50510.1    GGFJ01001370    MBW50511.1    KU543679    AMS38363.1   

Proteomes

UP000002358    UP000036403    UP000007819    UP000054359    UP000007266   

PRIDE

Q5NTZ0    Q7M4J4    V9H050    Q9BLI5   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF00004   AAA
PF17862   AAA_lid_3
PF16725   Nucleolin_bd
PF05485   THAP
PF05585   DUF1758
PF03564   DUF1759
PF05225   HTH_psq
PF00075   RNase_H

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR003959   ATPase_AAA_core       
IPR027417   P-loop_NTPase       
IPR003960   ATPase_AAA_CS       
IPR031996   NVL2_nucleolin-bd       
IPR041569   AAA_lid_3       
IPR003593   AAA+_ATPase       
IPR038100   NLV2_N_sf       
IPR001878   Znf_CCHC       
IPR036875   Znf_CCHC_sf       
IPR006612   THAP_Znf       
IPR005312   DUF1759       
IPR008737   Peptidase_asp_put       
IPR007889   HTH_Psq       
IPR036397   RNaseH_sf       
IPR012337   RNaseH-like_sf       
IPR002156   RNaseH_domain       
IPR013087   Znf_C2H2_type       

SUPFAM

SSF56219   SSF56219        + More
SSF52540   SSF52540       
SSF57756   SSF57756       
SSF53098   SSF53098       

Gene 3D

3.60.10.10     1.10.10.2010     3.30.420.10    

ProteinModelPortal

Q5NTZ0   Q7M4J4   V9H050   A0A1B6DRM7   A0A1B6E1N0   A0A023EYP7   + More
A0A224XAL8   K7JAI1   A0A0J7KTH2   J9KMZ9   J9LPJ1   K7JMI9   J9M9N3   X1XHQ0   A0A224X653   J9MA04   J9L798   J9K5I1   J9LPX1   J9LMF6   J9M8T8   J9KPX6   J9L0V3   J9M4Z2   J9LNF5   Q03277   J9LES5   X1WL18   J9K370   X1WUQ0   J9LPX0   J9M2E8   J9LVC2   J9KVB7   J9KRH3   J9LCW5   J9JY36   J9KPC7   A0A087UHT1   J9K2L0   Q9BLI5   J9KPE5   J9KA38   A0A139W914   J9LFF7   A0A142LX43   X1WVB5   Q868T0   A0A0K1IK14   A0A2M4CS98   A0A0K8VPH1   A0A2M4BBV9   A0A2M4BC01   A0A142LX37  

PDB

6A42     E-value=6.18057e-127,     Score=1168

KEGG

101741146    no KO assigned | (RefSeq) uncharacterized LOC101741146

GO

GO:0003964   GO:0005524   GO:0003676   GO:0008270   GO:0003677   GO:0004519   GO:0004523  

Length:

1271

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

13.75398

Exp number, first 60 AAs:

0.03318

Total prob of N-in:

0.01021

outside

1  -  1271

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0

CSRT

0

Interpretation

Uncertain