Gene

KWMTBOMO16783  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011681

Annotation

hypothetical_protein_KGM_02735_[Danaus_plexippus]

Location

Bomo_Scaf229(-):10616-11115      View in EpiBrowser

Full name

Phosphatidylinositol-4,5-bisphosphate 4-phosphatase      

Location in the cell

Extracellular   Reliability : 1.69 Nuclear   Reliability : 2.054

CDS

ATGGGGGACAGCCAAAGTGAAAATCAAGCTTTGCTGAGAATTGAAGAGGTCGCATGTGATGATGTGAGCACAATCTCCCCAATTGGGCCCGATGAGTTGCCTCCGCCATATCAACAAGTAGGGATGCCTATGGTCTCTTGCCGAGTGTGCCAAGCACTGATTGACATTCGTGGGAAAAAAGAGCAACATGTAGTGAAATGTTCAGAATGCAAAGAAGCTACGGTAAGGTTTATATGTTATTTTAACCTTTAA

Protein

MGDSQSENQALLRIEEVACDDVSTISPIGPDELPPPYQQVGMPMVSCRVCQALIDIRGKKEQHVVKCSECKEATVRFICYFNL

Description

Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate.

Catalytic Activity

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate

Uniprot

H9JQ75   A0A212FJF8   A0A2H1VUJ5   A0A194PVJ7   A0A194QNV5   A0A437BB77   + More
A0A0L7LRF5   A0A026W5N1   E1ZY00   A0A1B6E4J4   E2BUN7   A0A1Y1MRR0   N6UDK1   F4WCN4   A0A195CVA8   A0A158NHV0   A0A195EST2   V9IF38   A0A088AAD6   A0A0T6BCF1   A0A195DF83   A0A195BXM7   A0A2A3E9J5   D6WGR0   A0A1W4WSA0   A0A232FB15   K7INQ4   A0A0P4VM39   R4G8P1   A0A224XIJ2   A0A023F8S2   A0A0V0G581   A0A069DQ98   A0A1J1IIN6   A0A154PDV9   A0A423U0S9   A0A0L7QT21   A0A0N0BIU1   A0A2R7X604   A0A2M3Z324   A0A2M4ADJ5   W5JS14   A0A182F9Q6   A0A0M5IYE3   B0WRY3   B4J2T7   A0A1Q3FEI5   Q16QP8   A0A023EL41   A0A1B0CCN7   A0A182QH68   A0A182K2B3   A0A336MXE0   A0A182NH21   A0A182PJW4  

EC Number

3.1.3.78

Pubmed

19121390    22118469    26354079    26227816    24508170    30249741    + More
20798317    28004739    23537049    21719571    21347285    18362917    19820115    28648823    20075255    27129103    25474469    26334808    20920257    23761445    17994087    17510324    24945155   

EMBL

BABH01012031    AGBW02010462    AGBW02008266    OWR48475.1    OWR53878.1    ODYU01004527    + More
SOQ44505.1    KQ459590    KPI97347.1    KQ461190    KPJ07197.1    RSAL01000097    RVE47669.1    JTDY01000254    KOB78042.1    KK107403    QOIP01000011    EZA51313.1    RLU16720.1    GL435158    EFN73940.1    GEDC01023781    GEDC01004445    GEDC01002198    JAS13517.1    JAS32853.1    JAS35100.1    GL450732    EFN80590.1    GEZM01026131    JAV87220.1    APGK01027109    KB740648    KB632292    ENN79780.1    ERL91605.1    GL888070    EGI68214.1    KQ977259    KYN04606.1    ADTU01001749    KQ981979    KYN31310.1    JR042883    AEY59680.1    LJIG01001908    KRT85032.1    KQ980905    KYN11521.1    KQ976398    KYM92701.1    KZ288337    PBC27846.1    KQ971327    EFA01248.1    NNAY01000489    OXU28034.1    GDKW01000429    JAI56166.1    ACPB03006878    GAHY01000632    JAA76878.1    GFTR01004129    JAW12297.1    GBBI01000917    JAC17795.1    GECL01002923    JAP03201.1    GBGD01002651    JAC86238.1    CVRI01000054    CRL00056.1    KQ434870    KZC09594.1    QCYY01000847    ROT82311.1    KQ414755    KOC61770.1    KQ435727    KOX78048.1    KK856723    PTY26325.1    GGFM01002171    MBW22922.1    GGFK01005535    MBW38856.1    ADMH02000262    ETN67197.1    CP012525    ALC43268.1    DS232062    EDS33593.1    CH916366    EDV96078.1    GFDL01009086    JAV25959.1    CH477738    EAT36729.1    GAPW01003683    JAC09915.1    AJWK01006928    AXCN02000347    UFQT01003368    SSX34926.1   

Proteomes

UP000005204    UP000007151    UP000053268    UP000053240    UP000283053    UP000037510    + More
UP000053097    UP000279307    UP000000311    UP000008237    UP000019118    UP000030742    UP000007755    UP000078542    UP000005205    UP000078541    UP000005203    UP000078492    UP000078540    UP000242457    UP000007266    UP000192223    UP000215335    UP000002358    UP000015103    UP000183832    UP000076502    UP000283509    UP000053825    UP000053105    UP000000673    UP000069272    UP000092553    UP000002320    UP000001070    UP000008820    UP000092461    UP000075886    UP000075881    UP000075884    UP000075885   

PRIDE

H9JQ75   

Pfam

PF09788   Tmemb_55A        + More
PF09696   Ctf8

Interpro

IPR019178   PtdIns-P2-Ptase        + More
IPR018607   Ctf8       

ProteinModelPortal

H9JQ75   A0A212FJF8   A0A2H1VUJ5   A0A194PVJ7   A0A194QNV5   A0A437BB77   + More
A0A0L7LRF5   A0A026W5N1   E1ZY00   A0A1B6E4J4   E2BUN7   A0A1Y1MRR0   N6UDK1   F4WCN4   A0A195CVA8   A0A158NHV0   A0A195EST2   V9IF38   A0A088AAD6   A0A0T6BCF1   A0A195DF83   A0A195BXM7   A0A2A3E9J5   D6WGR0   A0A1W4WSA0   A0A232FB15   K7INQ4   A0A0P4VM39   R4G8P1   A0A224XIJ2   A0A023F8S2   A0A0V0G581   A0A069DQ98   A0A1J1IIN6   A0A154PDV9   A0A423U0S9   A0A0L7QT21   A0A0N0BIU1   A0A2R7X604   A0A2M3Z324   A0A2M4ADJ5   W5JS14   A0A182F9Q6   A0A0M5IYE3   B0WRY3   B4J2T7   A0A1Q3FEI5   Q16QP8   A0A023EL41   A0A1B0CCN7   A0A182QH68   A0A182K2B3   A0A336MXE0   A0A182NH21   A0A182PJW4  

KEGG

101741980    K13084 phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78] | (RefSeq) type 1 phosphati

PATHWAY

04070    Phosphatidylinositol signaling system - Bombyx mori (domestic silkworm)

GO

GO:0034597   GO:0016021   GO:0005765   GO:0031902   GO:0046856   GO:0007064   GO:0031390  

PANTHER

PTHR21014  

Subcellular location

Late endosome membrane  
Lysosome membrane  

Length:

83

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00112

Exp number, first 60 AAs:

0.00112

Total prob of N-in:

0.37370

outside

1  -  83

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0

CSRT

0

Interpretation

Uncertain