Gene

KWMTBOMO16757

Pre Gene Modal

BGIBMGA000932

Annotation

PREDICTED:_serine/threonine-protein_phosphatase_rdgC_[Bombyx_mori]

Location

Bomo_Scaf177(-):5538-21455      View in EpiBrowser

Full name

Serine/threonine-protein phosphatase with EF-hands       + More
Serine/threonine-protein phosphatase      
Serine/threonine-protein phosphatase rdgC      

Alternative Name

Retinal degeneration C protein

Location in the cell

Cytoplasmic   Reliability : 1.399 Mitochondrial   Reliability : 1.289 Nuclear   Reliability : 1.262

CDS

ATGCGATATAAAGAGATTTACGTGTCGCTTCTGCGGCCGCCGGTGATCGAGGGCTCAACGGCCGCGGAGTCGATAGATAAGGTGGAGTGGAAGCAGGTGTTTGATATACTGTGGTCGGATCCACAATGCATCGGAGGATGTGTGGCAAATGCGCTTCGAGGAGCAGGAACCTACTTCGGCCCTGATGTAACAGCGTCGTCGTTCCTCCAGAAGAATAAGCTGAGCTTCATAATTAGAAGTCACGAGTGCAAGCCCGGTGGATACGAAATCATGCATGGCGGTAATGTAATTACAATTTTCTCGGCGTCGAACTATTACGAGTTGGGTTCCAACAAGGGCGCTTACCTGAAACTATGCGGGAACTCGTTGGAGCGCCAGTTCGTGCAATACACGGCGGCCGTGTCTCGCACGCGGCGTCTCACCTTCAGGCAGCGGGTTGGCCTTGTCGAATCGTCCGCCATGAGGGAGCTACACAATCAGATTATGATGGCCAGGAGATCTCTGGAAGCTACTTTCCGTAGCTTGGACTCGGAGCAAAGTGGTTTCATATCTATAAGCGATTGGTGTCAAGCCATGGAGGAGACAACACACCTCGGTCTCCCGTGGAGGATGCTTAAAGACAAGCTTGTTCGCACAGATCCCGAGACACGCAAAGTACGTTACATGGATACATTCGAACTCAACACCAATAGGAACGGACGAAAATCTGACACGCTGACAGTCGTCGAGACTTTGTATAAAAATCAAAGAAGCTTGGAGGCGATCTTCAAGATATTGGATAAAGATAATTCTGGTTACATAACGTTGGAAGAATTTTCCGAGGCTTGCCAGCTGATCGGCAAGTACATGCCGAATCCGATGACGCAGGAGCAGCTCGTCGACATCTGTCGGCTCATGGACATCAACAAGGACGGCCTGGTTGATCTCAACGAGTTCCTCGAGAGTTTCCGTCTCGCCGAAAAGAGTTTACACGAGCAGGAAAGGATGTACGAAGACATGCAGGCTACCTGA

Protein

MRYKEIYVSLLRPPVIEGSTAAESIDKVEWKQVFDILWSDPQCIGGCVANALRGAGTYFGPDVTASSFLQKNKLSFIIRSHECKPGGYEIMHGGNVITIFSASNYYELGSNKGAYLKLCGNSLERQFVQYTAAVSRTRRLTFRQRVGLVESSAMRELHNQIMMARRSLEATFRSLDSEQSGFISISDWCQAMEETTHLGLPWRMLKDKLVRTDPETRKVRYMDTFELNTNRNGRKSDTLTVVETLYKNQRSLEAIFKILDKDNSGYITLEEFSEACQLIGKYMPNPMTQEQLVDICRLMDINKDGLVDLNEFLESFRLAEKSLHEQERMYEDMQAT

Description

Phosphatase required to prevent light-induced retinal degeneration.

Catalytic Activity

H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate
H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate

Cofactor

Mn(2+)

Similarity

Belongs to the PPP phosphatase family.

Keywords

Calcium   Complete proteome   Hydrolase   Magnesium   Manganese   Metal-binding   Protein phosphatase   Reference proteome   Repeat   Sensory transduction   Vision  

Feature

chain  Serine/threonine-protein phosphatase

Uniprot

H9IUK2   A0A194RLP1   A0A194PJL2   A0A437BJB7   A0A212EZK5   A0A2H1VHP4   + More
A0A2A4JTJ8   A0A0L7L4I0   A0A0T6AY67   D2A162   A0A1W4WIT1   A0A1B6HRT7   A0A1B6LRB5   N6UVB8   Q7Q2Z9   A0A224XB96   Q17FS3   A0A182K8J4   A0A182WR55   A0A182WF17   A0A1S4F4H5   U4US14   A0A067R243   A0A182RFE2   E0VT76   A0A182FTV4   A0A182NPL6   A0A1S4H6J9   A0A453YJM5   A0A084WI84   A0A182PU84   A0A1B6DP80   W5JP23   A0A1B6C198   A0A336KR11   A0A0A9XJD6   A0A1B0CWS4   A0A0L0BQ75   T1I8U1   A0A1I8ML02   A0A1I8QDX9   N6TJK7   B4QRV8   A0A182V902   A0A182MN75   A0A182IJK1   A0A0J9UPV3   B3NE58   P40421   A0A0R1E3V8   B4IA68   A0A0Q5UKB6   A0A0J9RYJ5   A0A0R1E263   A0A336KZ48   A0A0J9RZW2   A0A0Q5U6J1   B4PFC5   A0A1W4VUR9   A0A182G6D2   B3M4R3   A0A0P8XTZ4   W8ANN1   A0A0P8XTK4   B4MKU9   A0A034WBT5   A0A3B0KHY3   A0A1A9VSD6   A0A0R3P7M8   A0A0R3P3H1   A0A1A9UQS4   A0A0R3P3E4   A0A3B0K9C5   A0A1A9Z5T7   A0A0R3P3C9   B5DPA9   B4GR08   A0A1A9WRH1   B4LG02   A0A0Q9WVD8   A0A1D2MFK2   A0A1B0G8C3   A0A0M4EZY5   A0A1A9Z4V7   B4KV71   A0A0Q9XQA2   B4IYR3   A0A1B0G581   A0A0Q9XDH4   A0A226E4L8   A0A2P2I617   A0A131XLU5   A0A224Z6H9   A0A131YUK5   A0A1E1XP01   A0A1B0B3L8   A0A1A9Z2Z5   A0A293LIW1   A0A147BQQ3  

EC Number

3.1.3.16

Pubmed

19121390    26354079    22118469    26227816    18362917    19820115    + More
23537049    12364791    17510324    24845553    20566863    24438588    20920257    23761445    25401762    26823975    26108605    25315136    17994087    22936249    1316807    10731132    12537572    17550304    26483478    24495485    25348373    15632085    23185243    18057021    27289101    28049606    28797301    26830274    29209593    29652888   

EMBL

BABH01000935    KQ460205    KPJ16901.1    KQ459606    KPI91275.1    RSAL01000047    + More
RVE50532.1    AGBW02011268    OWR46920.1    ODYU01002624    SOQ40363.1    NWSH01000662    PCG74944.1    JTDY01003056    KOB70236.1    LJIG01022522    KRT80131.1    KQ971338    EFA01582.2    GECU01030324    JAS77382.1    GEBQ01013744    JAT26233.1    APGK01009376    APGK01009377    KB737932    ENN82832.1    AAAB01008966    EAA12933.4    GFTR01006749    JAW09677.1    CH477268    EAT45428.1    KB632337    ERL92855.1    KK852756    KDR17087.1    DS235760    EEB16582.1    APCN01001959    APCN01001960    ATLV01023923    KE525347    KFB49928.1    GEDC01009827    JAS27471.1    ADMH02000929    ETN64645.1    GEDC01030006    JAS07292.1    UFQS01000791    UFQT01000791    SSX06909.1    SSX27253.1    GBHO01023525    GBHO01023524    GDHC01015922    JAG20079.1    JAG20080.1    JAQ02707.1    AJWK01032810    AJWK01032811    JRES01001542    KNC22133.1    ACPB03022158    ACPB03022159    APGK01023024    KB740457    ENN80624.1    CM000363    EDX11204.1    AXCM01005116    CM002912    KMZ00726.1    CH954178    EDV52482.1    M89628    AE014296    BT015959    CM000159    KRK02292.1    CH480826    EDW44181.1    KQS44298.1    KMZ00727.1    KRK02291.1    UFQS01001279    UFQT01001279    SSX10107.1    SSX29829.1    KMZ00725.1    KQS44297.1    EDW95211.1    JXUM01007767    JXUM01007768    JXUM01007769    JXUM01007770    JXUM01007771    JXUM01007772    KQ560247    KXJ83583.1    CH902618    EDV39462.1    KPU78057.1    GAMC01016156    GAMC01016155    JAB90400.1    KPU78056.1    CH963847    EDW72874.2    GAKP01007729    JAC51223.1    OUUW01000009    SPP84721.1    CH379069    KRT07669.1    KRT07673.1    KRT07672.1    SPP84720.1    KRT07671.1    EDY73443.1    CH479188    EDW40193.1    CH940647    EDW70401.1    KRF84894.1    LJIJ01001427    ODM91769.1    CCAG010000237    CP012525    ALC44362.1    CH933809    EDW19411.1    KRG06631.1    CH916366    EDV96600.1    CCAG010004851    KRG06630.1    LNIX01000006    OXA52533.1    IACF01003719    LAB69330.1    GEFH01001259    JAP67322.1    GFPF01011705    MAA22851.1    GEDV01005900    JAP82657.1    GFAA01002374    JAU01061.1    JXJN01007898    JXJN01007899    GFWV01003041    MAA27771.1    GEGO01002314    JAR93090.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000283053    UP000007151    UP000218220    + More
UP000037510    UP000007266    UP000192223    UP000019118    UP000007062    UP000008820    UP000075881    UP000076407    UP000075920    UP000030742    UP000027135    UP000075900    UP000009046    UP000069272    UP000075884    UP000075840    UP000030765    UP000075885    UP000000673    UP000092461    UP000037069    UP000015103    UP000095301    UP000095300    UP000000304    UP000075903    UP000075883    UP000075880    UP000008711    UP000000803    UP000002282    UP000001292    UP000192221    UP000069940    UP000249989    UP000007801    UP000007798    UP000268350    UP000078200    UP000001819    UP000092445    UP000008744    UP000091820    UP000008792    UP000094527    UP000092444    UP000092553    UP000009192    UP000001070    UP000198287    UP000092460   

PRIDE

H9IUK2    P40421   

Pfam

PF13499   EF-hand_7        + More
PF00612   IQ
PF00149   Metallophos
PF13202   EF-hand_5
PF13833   EF-hand_8
PF08321   PPP5

Interpro

IPR002048   EF_hand_dom        + More
IPR011992   EF-hand-dom_pair       
IPR029052   Metallo-depent_PP-like       
IPR012008   Ser/Thr-Pase_EF-hand_contain       
IPR006186   Ser/Thr-sp_prot-phosphatase       
IPR018247   EF_Hand_1_Ca_BS       
IPR000048   IQ_motif_EF-hand-BS       
IPR004843   Calcineurin-like_PHP_ApaH       
IPR013235   PPP_dom       
IPR041767   MPP_RdgC       

SUPFAM

SSF47473   SSF47473       

Gene 3D

3.60.21.10    

CDD

cd00051  EFh
cd07420  MPP_RdgC

ProteinModelPortal

H9IUK2   A0A194RLP1   A0A194PJL2   A0A437BJB7   A0A212EZK5   A0A2H1VHP4   + More
A0A2A4JTJ8   A0A0L7L4I0   A0A0T6AY67   D2A162   A0A1W4WIT1   A0A1B6HRT7   A0A1B6LRB5   N6UVB8   Q7Q2Z9   A0A224XB96   Q17FS3   A0A182K8J4   A0A182WR55   A0A182WF17   A0A1S4F4H5   U4US14   A0A067R243   A0A182RFE2   E0VT76   A0A182FTV4   A0A182NPL6   A0A1S4H6J9   A0A453YJM5   A0A084WI84   A0A182PU84   A0A1B6DP80   W5JP23   A0A1B6C198   A0A336KR11   A0A0A9XJD6   A0A1B0CWS4   A0A0L0BQ75   T1I8U1   A0A1I8ML02   A0A1I8QDX9   N6TJK7   B4QRV8   A0A182V902   A0A182MN75   A0A182IJK1   A0A0J9UPV3   B3NE58   P40421   A0A0R1E3V8   B4IA68   A0A0Q5UKB6   A0A0J9RYJ5   A0A0R1E263   A0A336KZ48   A0A0J9RZW2   A0A0Q5U6J1   B4PFC5   A0A1W4VUR9   A0A182G6D2   B3M4R3   A0A0P8XTZ4   W8ANN1   A0A0P8XTK4   B4MKU9   A0A034WBT5   A0A3B0KHY3   A0A1A9VSD6   A0A0R3P7M8   A0A0R3P3H1   A0A1A9UQS4   A0A0R3P3E4   A0A3B0K9C5   A0A1A9Z5T7   A0A0R3P3C9   B5DPA9   B4GR08   A0A1A9WRH1   B4LG02   A0A0Q9WVD8   A0A1D2MFK2   A0A1B0G8C3   A0A0M4EZY5   A0A1A9Z4V7   B4KV71   A0A0Q9XQA2   B4IYR3   A0A1B0G581   A0A0Q9XDH4   A0A226E4L8   A0A2P2I617   A0A131XLU5   A0A224Z6H9   A0A131YUK5   A0A1E1XP01   A0A1B0B3L8   A0A1A9Z2Z5   A0A293LIW1   A0A147BQQ3  

PDB

3H69     E-value=4.56791e-21,     Score=249

KEGG

101744368    K13807 serine/threonine-protein phosphatase with EF-hands [EC:3.1.3.16] | (RefSeq) serine/threonine-

PATHWAY

04745    Phototransduction - fly - Bombyx mori (domestic silkworm)

GO

GO:0050906   GO:0005506   GO:0030145   GO:0004721   GO:0005509   GO:0016787   GO:0005829   GO:0005634   GO:0004722   GO:0016021   GO:0043052   GO:0006470   GO:0007601   GO:0019722   GO:0005516   GO:0005737   GO:0004723   GO:0016059   GO:0007602   GO:0020037   GO:0016020   GO:0004888   GO:0007166   GO:0016773   GO:0006096   GO:0006281   GO:0006259  

Length:

336

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0167

Exp number, first 60 AAs:

0.0024

Total prob of N-in:

0.03933

outside

1  -  336

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0

CSRT

0

Interpretation

Uncertain