Gene

KWMTBOMO16683  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011681

Annotation

hypothetical_protein_KGM_02735_[Danaus_plexippus]

Location

Bomo_Scaf093(+):5446-6186      View in EpiBrowser

Full name

Phosphatidylinositol-4,5-bisphosphate 4-phosphatase      

Location in the cell

Extracellular   Reliability : 1.354 Nuclear   Reliability : 1.945

CDS

ATGGGGGACAGCCAAAGTGAAAATCAAGCTTTGCTGAGAATTGAAGAGGTCGCATGTGATGATGTGAGCACAATCTCCCCAATTGGGCCCGATGAGTTGCCTCCGCCATATCAACAAGTAGGGATGCCTATGGTCTCTTGCCGAGTGTGCCAAGCACTGATTGACATTCGTGGGAAAAAAGAGCAACATGTAGTGAAATGTTCAGAATGCAAAGAAGCTACGCATTTAATAGCTTAG

Protein

MGDSQSENQALLRIEEVACDDVSTISPIGPDELPPPYQQVGMPMVSCRVCQALIDIRGKKEQHVVKCSECKEATHLIA

Description

Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate.

Catalytic Activity

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate

Feature

chain  Phosphatidylinositol-4,5-bisphosphate 4-phosphatase

Uniprot

H9JQ75   A0A212FJF8   A0A2H1VUJ5   A0A194PVJ7   A0A194QNV5   A0A0L7LRF5   + More
A0A1Y1MRR0   N6UDK1   A0A026W5N1   E1ZY00   A0A1B6E4J4   A0A0K8TPL3   E2BUN7   A0A0J7KM32   A0A0T6BCF1   A0A195EST2   F4WCN4   A0A195CVA8   A0A158NHV0   V9IF38   A0A088AAD6   A0A195DF83   A0A195BXM7   A0A2A3E9J5   A0A1W4WSA0   A0A2P8ZA78   D6WGR0   A0A232FB15   K7INQ4   B4MLX7   A0A067R6E0   A0A0P4VM39   R4G8P1   B4J2T7   A0A0V0G581   A0A224XIJ2   A0A023F8S2   A0A069DQ98   A0A2J7Q6I5   A0A0L0CNR1   A0A1J1IIN6   A0A154PDV9   A0A1B0CCN7   A0A0L7QT21   A0A210PT34   A0A0N0BIU1   A0A182LLI7   A0A1L8D8Z7   A0A1L8D995   A0A2R7X604   A0A2M3Z324   A0A2M4ADJ5   W5JS14   A0A182F9Q6   A0A0M5IYE3   B0WRY3   A0A1Q3FEI5   T1PMP4   A0A023EL41   Q16QP8   E9FV10   A0A1I8NZI8   A0A182QH68   A0A1L8EH74   A0A0A9WPB4   A0A1I8M503   A0A182K2B3  

EC Number

3.1.3.78

Pubmed

19121390    22118469    26354079    26227816    28004739    23537049    + More
24508170    30249741    20798317    26369729    21719571    21347285    29403074    18362917    19820115    28648823    20075255    17994087    24845553    27129103    25474469    26334808    26108605    28812685    20966253    20920257    23761445    24945155    17510324    21292972    25401762    25315136   

EMBL

BABH01012031    AGBW02010462    AGBW02008266    OWR48475.1    OWR53878.1    ODYU01004527    + More
SOQ44505.1    KQ459590    KPI97347.1    KQ461190    KPJ07197.1    JTDY01000254    KOB78042.1    GEZM01026131    JAV87220.1    APGK01027109    KB740648    KB632292    ENN79780.1    ERL91605.1    KK107403    QOIP01000011    EZA51313.1    RLU16720.1    GL435158    EFN73940.1    GEDC01023781    GEDC01004445    GEDC01002198    JAS13517.1    JAS32853.1    JAS35100.1    GDAI01001773    JAI15830.1    GL450732    EFN80590.1    LBMM01005673    KMQ91299.1    LJIG01001908    KRT85032.1    KQ981979    KYN31310.1    GL888070    EGI68214.1    KQ977259    KYN04606.1    ADTU01001749    JR042883    AEY59680.1    KQ980905    KYN11521.1    KQ976398    KYM92701.1    KZ288337    PBC27846.1    PYGN01000129    PSN53400.1    KQ971327    EFA01248.1    NNAY01000489    OXU28034.1    CH963847    EDW73188.1    KK852855    KDR14912.1    GDKW01000429    JAI56166.1    ACPB03006878    GAHY01000632    JAA76878.1    CH916366    EDV96078.1    GECL01002923    JAP03201.1    GFTR01004129    JAW12297.1    GBBI01000917    JAC17795.1    GBGD01002651    JAC86238.1    NEVH01017474    PNF24188.1    JRES01000234    KNC33089.1    CVRI01000054    CRL00056.1    KQ434870    KZC09594.1    AJWK01006928    KQ414755    KOC61770.1    NEDP02005518    OWF39641.1    KQ435727    KOX78048.1    GFDF01011153    JAV02931.1    GFDF01011167    JAV02917.1    KK856723    PTY26325.1    GGFM01002171    MBW22922.1    GGFK01005535    MBW38856.1    ADMH02000262    ETN67197.1    CP012525    ALC43268.1    DS232062    EDS33593.1    GFDL01009086    JAV25959.1    KA650056    AFP64685.1    GAPW01003683    JAC09915.1    CH477738    EAT36729.1    GL732525    EFX88823.1    AXCN02000347    GFDG01000856    JAV17943.1    GBHO01034323    GBHO01008803    JAG09281.1    JAG34801.1   

Proteomes

UP000005204    UP000007151    UP000053268    UP000053240    UP000037510    UP000019118    + More
UP000030742    UP000053097    UP000279307    UP000000311    UP000008237    UP000036403    UP000078541    UP000007755    UP000078542    UP000005205    UP000005203    UP000078492    UP000078540    UP000242457    UP000192223    UP000245037    UP000007266    UP000215335    UP000002358    UP000007798    UP000027135    UP000015103    UP000001070    UP000235965    UP000037069    UP000183832    UP000076502    UP000092461    UP000053825    UP000242188    UP000053105    UP000075882    UP000000673    UP000069272    UP000092553    UP000002320    UP000008820    UP000000305    UP000095300    UP000075886    UP000095301    UP000075881   

PRIDE

H9JQ75   

Pfam

PF09788   Tmemb_55A        + More
PF18091   E3_UbLigase_RBR
PF09696   Ctf8

Interpro

IPR019178   PtdIns-P2-Ptase        + More
IPR041031   RNF31_C       
IPR018607   Ctf8       

ProteinModelPortal

H9JQ75   A0A212FJF8   A0A2H1VUJ5   A0A194PVJ7   A0A194QNV5   A0A0L7LRF5   + More
A0A1Y1MRR0   N6UDK1   A0A026W5N1   E1ZY00   A0A1B6E4J4   A0A0K8TPL3   E2BUN7   A0A0J7KM32   A0A0T6BCF1   A0A195EST2   F4WCN4   A0A195CVA8   A0A158NHV0   V9IF38   A0A088AAD6   A0A195DF83   A0A195BXM7   A0A2A3E9J5   A0A1W4WSA0   A0A2P8ZA78   D6WGR0   A0A232FB15   K7INQ4   B4MLX7   A0A067R6E0   A0A0P4VM39   R4G8P1   B4J2T7   A0A0V0G581   A0A224XIJ2   A0A023F8S2   A0A069DQ98   A0A2J7Q6I5   A0A0L0CNR1   A0A1J1IIN6   A0A154PDV9   A0A1B0CCN7   A0A0L7QT21   A0A210PT34   A0A0N0BIU1   A0A182LLI7   A0A1L8D8Z7   A0A1L8D995   A0A2R7X604   A0A2M3Z324   A0A2M4ADJ5   W5JS14   A0A182F9Q6   A0A0M5IYE3   B0WRY3   A0A1Q3FEI5   T1PMP4   A0A023EL41   Q16QP8   E9FV10   A0A1I8NZI8   A0A182QH68   A0A1L8EH74   A0A0A9WPB4   A0A1I8M503   A0A182K2B3  

KEGG

101741980    K13084 phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78] | (RefSeq) type 1 phosphati

GO

GO:0034597   GO:0016021   GO:0005765   GO:0031902   GO:0046856   GO:0007064   GO:0031390  

PANTHER

PTHR21014  

Subcellular location

Late endosome membrane  
Lysosome membrane  

Length:

78

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00113

Exp number, first 60 AAs:

0.00113

Total prob of N-in:

0.37288

outside

1  -  78

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0

CSRT

0

Interpretation

Uncertain