SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO16669  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA013349
Annotation
PREDICTED:_adapter_molecule_Crk_isoform_X1_[Papilio_polytes]
Full name
Adapter molecule Crk      
Location in the cell
Cytoplasmic   Reliability : 1.122
 

Sequence

CDS
ATGGCGAATTCCGGAATGGGGGGTTCCTTCGACCCCAATGACATGAGCAGCTGGTACTTTCACGGCATGACGCGGAAAGAAGCTACAGATCTGCTCCTTAATGAGACTGAGAGTGGCGTGTTTCTGGTCAGGGATTCGAAGTCCATTGTTGGAAACTACGTTCTTTGCGTCAAAGAAGCAGGTCGGGTGTCGAACTATATAATCGATCGCATCGTTTCACCCGACGGCTCGGTGCTCTTCCGCATCGGAGACCAGGTGTTCGTGGACATGGCGGCGCTGTTGTCGTTCTACCGCGTCCACTACTTGGACACGACGGCGCTGGTGAGGCCCTACGCGAGGACGGCCATCGCTCACCAGCCCTCCGCAGCAGAACCAGACCCTAGAGATAGTTATCGCGAAGTTCGATTTCGCTGGCAACGTGAGTAA
Protein
MANSGMGGSFDPNDMSSWYFHGMTRKEATDLLLNETESGVFLVRDSKSIVGNYVLCVKEAGRVSNYIIDRIVSPDGSVLFRIGDQVFVDMAALLSFYRVHYLDTTALVRPYARTAIAHQPSAAEPDPRDSYREVRFRWQRE

Summary

Description
Adapter protein which interacts with C-terminal portion of mbc, homolog of human DOCK180. May play a role in cellular processes throughout development.
Similarity
Belongs to the CRK family.
Keywords
Complete proteome   Developmental protein   Reference proteome   Repeat   SH2 domain   SH3 domain  
Feature
chain  Adapter molecule Crk
EMBL
NWSH01002557    PCG67995.1    RSAL01000085    RVE48335.1    KQ460466    KPJ14615.1    + More
KQ459597    KPI95240.1    JTDY01000379    KOB77468.1    KK113338    KFM59908.1    GGFK01009145    MBW42466.1    ADMH02001881    ETN60685.1    GEZM01037757    JAV81958.1    UFQS01000668    UFQT01000668    SSX05974.1    SSX26331.1    GFDL01014271    JAV20774.1    GGFJ01008162    MBW57303.1    AAAB01008839    EAA05910.3    GFDL01014577    JAV20468.1    APCN01004569    GFDF01006715    JAV07369.1    AJWK01017609    DS231844    EDS35722.1    AXCN02000858    AXCM01000440    AAZX01007094    NNAY01001690    OXU23215.1    GDKW01002713    JAI53882.1    ACPB03016929    GBBI01002414    JAC16298.1    GECL01002049    JAP04075.1    GBGD01002564    JAC86325.1    GFTR01004291    JAW12135.1    CH477394    EAT41873.1    GBHO01040387    GBHO01040385    GBHO01040384    GBHO01040383    GBHO01040382    GBHO01014703    GBRD01003779    GDHC01010176    JAG03217.1    JAG03219.1    JAG03220.1    JAG03221.1    JAG03222.1    JAG28901.1    JAG62042.1    JAQ08453.1    ATLV01015007    KE524999    KFB39875.1    JXUM01005913    JXUM01084232    JXUM01084233    KQ560204    KXJ83839.1    GDIP01214002    GDIP01152781    GDIP01115860    JAJ09400.1    GEDC01003037    JAS34261.1    BDGG01000002    GAU92974.1    GFAC01003904    JAT95284.1    GEBQ01025302    GEBQ01011037    JAT14675.1    JAT28940.1    AFFK01016682    GECU01031934    GECU01016312    GECU01014205    JAS75772.1    JAS91394.1    JAS93501.1    GECZ01012997    JAS56772.1    NCKU01003150    RWS08075.1    DS235335    EEB14860.1    LBMM01006501    KMQ90561.1    CVRI01000021    CRK91464.1    LNIX01000020    OXA44014.1    PYGN01000816    PSN40416.1    GEDC01015366    JAS21932.1    QOIP01000011    RLU17132.1    GL439967    EFN66497.1    GL452770    EFN76830.1    KQ982708    KYQ51792.1    GL767674    EFZ13209.1    GL888206    EGI65186.1    KQ434931    KZC11834.1    KZ288288    PBC29322.1    NEVH01009083    PNF33725.1    CH933813    KRG07215.1    GGLE01006575    MBY10701.1    GFXV01007252    MBW19057.1    KQ971307    EFA11162.1    GEFH01004420    JAP64161.1    GFPF01011106    MAA22252.1    GEDV01007327    JAP81230.1    KQ435689    KOX81245.1    GDAI01002912    JAI14691.1    GACK01007966    JAA57068.1    GFXV01006058    MBW17863.1    GDHF01020245    JAI32069.1    AE014135    AFH06772.1    KA648160    AFP62789.1    GBYB01006455    JAG76222.1    LJIG01000734    KRT86206.1    CH964272    EDW83566.2    LJIJ01000258    ODM99737.1    GAKP01000258    GAKP01000257    JAC58695.1    GGMR01018165    MBY30784.1    GDHF01033081    GDHF01031633    GDHF01030801    GDHF01008551    GDHF01007068    JAI19233.1    JAI20681.1    JAI21513.1    JAI43763.1    JAI45246.1    CH954184    EDV45264.1    CM002916    KMZ07168.1    CH480867    EDW53719.1    AF112976    BT012456   
Pfam
PF00017   SH2        + More
PF07653   SH3_2
PF00018   SH3_1
PF07690   MFS_1
Interpro
IPR036860   SH2_dom_sf        + More
IPR001452   SH3_domain       
IPR000980   SH2       
IPR035458   CRK_SH3_C       
IPR036028   SH3-like_dom_sf       
IPR035457   CRK_SH3_N       
IPR020846   MFS_dom       
IPR036259   MFS_trans_sf       
IPR011701   MFS       
SUPFAM
SSF55550   SSF55550        + More
SSF50044   SSF50044       
SSF103473   SSF103473       
Gene 3D
PDB
2EYZ     E-value=1.0836e-20,     Score=240

Ontologies

Topology

Length:
141
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.16389
Exp number, first 60 AAs:
0.00088
Total prob of N-in:
0.07022
outside
1  -  141
 
 

Population Genetic Test Statistics

Pi
0
Theta
0
Tajima's D
0
CLR
0
CSRT
0
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
26280517 KYYVHNDIFR 100.00 4e-14
26822097 YIEIFMNSAPGAGGFK 100.00 2e-12
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