Gene

KWMTBOMO16669  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013349

Annotation

PREDICTED:_adapter_molecule_Crk_isoform_X1_[Papilio_polytes]

Location

Bomo_Scaf082(+):20786-25700      View in EpiBrowser

Full name

Adapter molecule Crk      

Location in the cell

Cytoplasmic   Reliability : 1.122

CDS

ATGGCGAATTCCGGAATGGGGGGTTCCTTCGACCCCAATGACATGAGCAGCTGGTACTTTCACGGCATGACGCGGAAAGAAGCTACAGATCTGCTCCTTAATGAGACTGAGAGTGGCGTGTTTCTGGTCAGGGATTCGAAGTCCATTGTTGGAAACTACGTTCTTTGCGTCAAAGAAGCAGGTCGGGTGTCGAACTATATAATCGATCGCATCGTTTCACCCGACGGCTCGGTGCTCTTCCGCATCGGAGACCAGGTGTTCGTGGACATGGCGGCGCTGTTGTCGTTCTACCGCGTCCACTACTTGGACACGACGGCGCTGGTGAGGCCCTACGCGAGGACGGCCATCGCTCACCAGCCCTCCGCAGCAGAACCAGACCCTAGAGATAGTTATCGCGAAGTTCGATTTCGCTGGCAACGTGAGTAA

Protein

MANSGMGGSFDPNDMSSWYFHGMTRKEATDLLLNETESGVFLVRDSKSIVGNYVLCVKEAGRVSNYIIDRIVSPDGSVLFRIGDQVFVDMAALLSFYRVHYLDTTALVRPYARTAIAHQPSAAEPDPRDSYREVRFRWQRE

Description

Adapter protein which interacts with C-terminal portion of mbc, homolog of human DOCK180. May play a role in cellular processes throughout development.

Similarity

Belongs to the CRK family.

Keywords

Complete proteome   Developmental protein   Reference proteome   Repeat   SH2 domain   SH3 domain  

Feature

chain  Adapter molecule Crk

Uniprot

A0A2A4J7D4   A0A3S2LJZ6   A0A0N0PCV4   A0A194PVT4   A0A0L7LPM1   A0A182PA74   + More
A0A087T469   A0A2M4ANU7   W5JCS8   A0A1Y1MAE5   A0A336KM49   A0A1Q3EZQ3   A0A2M4BW92   A0A182F565   A0A182KGM0   A0A1S4EKH5   Q7QG48   A0A1Q3EZ01   A0A182L5K4   A0A182TLI5   A0A182V0U0   A0A182X0E4   A0A182IE55   A0A1L8DLM6   A0A1B0CLT4   B0W5R9   A0A1S4J6E9   A0A182R117   A0A182M0X9   A0A182Y5V6   A0A182RGE0   K7IWQ3   A0A232EY17   A0A0P4VQ02   T1I0P2   A0A023F5B5   A0A0V0G7J0   A0A069DR22   A0A224XI25   A0A182IPR7   Q0IF64   A0A0A9WED1   A0A084VPI1   A0A182GSA0   A0A0P4ZQ04   A0A1B6E8K2   A0A1S3HHJ2   A0A1D1UTG6   A0A1E1X7T4   A0A1B6KTB1   T1JIX5   A0A1B6IWS6   A0A1B6G2X3   A0A3S4QUX1   E0VNA4   A0A0J7KK00   A0A1J1HTR5   A0A182NEG3   A0A226DGP1   A0A2P8Y829   A0A1B6D8E3   A0A3L8DAF9   E2AJ57   E2C5L7   A0A151WV37   E9J1P7   F4WKU4   A0A154PK49   A0A2A3EDF2   A0A2J7QYR6   A0A0Q9XF90   A0A2R5LMG8   A0A2H8TXT9   D6W7Z9   A0A131XES9   A0A224Z7A0   A0A131YRY2   A0A0M9ABN6   A0A0K8TKN9   A0A1I8P005   L7M1T1   A0A1W4WXR1   A0A2H8TUB2   A0A0K8UZH7   H9XVM7   T1PJ65   A0A0C9RDQ4   A0A0T6BG36   B4NHJ7   A0A1D2N376   A0A034WWY5   A0A2S2PN28   A0A0K8U2F3   A0A1A9WKY9   B3P9V1   A0A0J9S0Q9   B4IL88   Q9XYM0  

Pubmed

26354079    26227816    20920257    23761445    28004739    12364791    + More
20966253    25244985    20075255    28648823    27129103    25474469    26334808    17510324    25401762    26823975    24438588    26483478    27649274    28503490    20566863    29403074    30249741    20798317    21282665    21719571    17994087    18362917    19820115    28049606    28797301    26830274    26369729    25576852    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    25315136    27289101    25348373    22936249    10072777   

EMBL

NWSH01002557    PCG67995.1    RSAL01000085    RVE48335.1    KQ460466    KPJ14615.1    + More
KQ459597    KPI95240.1    JTDY01000379    KOB77468.1    KK113338    KFM59908.1    GGFK01009145    MBW42466.1    ADMH02001881    ETN60685.1    GEZM01037757    JAV81958.1    UFQS01000668    UFQT01000668    SSX05974.1    SSX26331.1    GFDL01014271    JAV20774.1    GGFJ01008162    MBW57303.1    AAAB01008839    EAA05910.3    GFDL01014577    JAV20468.1    APCN01004569    GFDF01006715    JAV07369.1    AJWK01017609    DS231844    EDS35722.1    AXCN02000858    AXCM01000440    AAZX01007094    NNAY01001690    OXU23215.1    GDKW01002713    JAI53882.1    ACPB03016929    GBBI01002414    JAC16298.1    GECL01002049    JAP04075.1    GBGD01002564    JAC86325.1    GFTR01004291    JAW12135.1    CH477394    EAT41873.1    GBHO01040387    GBHO01040385    GBHO01040384    GBHO01040383    GBHO01040382    GBHO01014703    GBRD01003779    GDHC01010176    JAG03217.1    JAG03219.1    JAG03220.1    JAG03221.1    JAG03222.1    JAG28901.1    JAG62042.1    JAQ08453.1    ATLV01015007    KE524999    KFB39875.1    JXUM01005913    JXUM01084232    JXUM01084233    KQ560204    KXJ83839.1    GDIP01214002    GDIP01152781    GDIP01115860    JAJ09400.1    GEDC01003037    JAS34261.1    BDGG01000002    GAU92974.1    GFAC01003904    JAT95284.1    GEBQ01025302    GEBQ01011037    JAT14675.1    JAT28940.1    AFFK01016682    GECU01031934    GECU01016312    GECU01014205    JAS75772.1    JAS91394.1    JAS93501.1    GECZ01012997    JAS56772.1    NCKU01003150    RWS08075.1    DS235335    EEB14860.1    LBMM01006501    KMQ90561.1    CVRI01000021    CRK91464.1    LNIX01000020    OXA44014.1    PYGN01000816    PSN40416.1    GEDC01015366    JAS21932.1    QOIP01000011    RLU17132.1    GL439967    EFN66497.1    GL452770    EFN76830.1    KQ982708    KYQ51792.1    GL767674    EFZ13209.1    GL888206    EGI65186.1    KQ434931    KZC11834.1    KZ288288    PBC29322.1    NEVH01009083    PNF33725.1    CH933813    KRG07215.1    GGLE01006575    MBY10701.1    GFXV01007252    MBW19057.1    KQ971307    EFA11162.1    GEFH01004420    JAP64161.1    GFPF01011106    MAA22252.1    GEDV01007327    JAP81230.1    KQ435689    KOX81245.1    GDAI01002912    JAI14691.1    GACK01007966    JAA57068.1    GFXV01006058    MBW17863.1    GDHF01020245    JAI32069.1    AE014135    AFH06772.1    KA648160    AFP62789.1    GBYB01006455    JAG76222.1    LJIG01000734    KRT86206.1    CH964272    EDW83566.2    LJIJ01000258    ODM99737.1    GAKP01000258    GAKP01000257    JAC58695.1    GGMR01018165    MBY30784.1    GDHF01033081    GDHF01031633    GDHF01030801    GDHF01008551    GDHF01007068    JAI19233.1    JAI20681.1    JAI21513.1    JAI43763.1    JAI45246.1    CH954184    EDV45264.1    CM002916    KMZ07168.1    CH480867    EDW53719.1    AF112976    BT012456   

Proteomes

UP000218220    UP000283053    UP000053240    UP000053268    UP000037510    UP000075885    + More
UP000054359    UP000000673    UP000069272    UP000075881    UP000079169    UP000007062    UP000075882    UP000075902    UP000075903    UP000076407    UP000075840    UP000092461    UP000002320    UP000075886    UP000075883    UP000076408    UP000075900    UP000002358    UP000215335    UP000015103    UP000075880    UP000008820    UP000030765    UP000069940    UP000249989    UP000085678    UP000186922    UP000285301    UP000009046    UP000036403    UP000183832    UP000075884    UP000198287    UP000245037    UP000279307    UP000000311    UP000008237    UP000075809    UP000007755    UP000076502    UP000242457    UP000235965    UP000009192    UP000007266    UP000053105    UP000095300    UP000192223    UP000000803    UP000095301    UP000007798    UP000094527    UP000091820    UP000008711    UP000001292   

PRIDE

Q9XYM0   

Pfam

PF00017   SH2        + More
PF07653   SH3_2
PF00018   SH3_1
PF07690   MFS_1

Interpro

IPR036860   SH2_dom_sf        + More
IPR001452   SH3_domain       
IPR000980   SH2       
IPR035458   CRK_SH3_C       
IPR036028   SH3-like_dom_sf       
IPR035457   CRK_SH3_N       
IPR020846   MFS_dom       
IPR036259   MFS_trans_sf       
IPR011701   MFS       

SUPFAM

SSF55550   SSF55550        + More
SSF50044   SSF50044       
SSF103473   SSF103473       

Gene 3D

3.30.505.10    

CDD

cd11759  SH3_CRK_C
cd11758  SH3_CRK_N
cd06174  MFS

ProteinModelPortal

A0A2A4J7D4   A0A3S2LJZ6   A0A0N0PCV4   A0A194PVT4   A0A0L7LPM1   A0A182PA74   + More
A0A087T469   A0A2M4ANU7   W5JCS8   A0A1Y1MAE5   A0A336KM49   A0A1Q3EZQ3   A0A2M4BW92   A0A182F565   A0A182KGM0   A0A1S4EKH5   Q7QG48   A0A1Q3EZ01   A0A182L5K4   A0A182TLI5   A0A182V0U0   A0A182X0E4   A0A182IE55   A0A1L8DLM6   A0A1B0CLT4   B0W5R9   A0A1S4J6E9   A0A182R117   A0A182M0X9   A0A182Y5V6   A0A182RGE0   K7IWQ3   A0A232EY17   A0A0P4VQ02   T1I0P2   A0A023F5B5   A0A0V0G7J0   A0A069DR22   A0A224XI25   A0A182IPR7   Q0IF64   A0A0A9WED1   A0A084VPI1   A0A182GSA0   A0A0P4ZQ04   A0A1B6E8K2   A0A1S3HHJ2   A0A1D1UTG6   A0A1E1X7T4   A0A1B6KTB1   T1JIX5   A0A1B6IWS6   A0A1B6G2X3   A0A3S4QUX1   E0VNA4   A0A0J7KK00   A0A1J1HTR5   A0A182NEG3   A0A226DGP1   A0A2P8Y829   A0A1B6D8E3   A0A3L8DAF9   E2AJ57   E2C5L7   A0A151WV37   E9J1P7   F4WKU4   A0A154PK49   A0A2A3EDF2   A0A2J7QYR6   A0A0Q9XF90   A0A2R5LMG8   A0A2H8TXT9   D6W7Z9   A0A131XES9   A0A224Z7A0   A0A131YRY2   A0A0M9ABN6   A0A0K8TKN9   A0A1I8P005   L7M1T1   A0A1W4WXR1   A0A2H8TUB2   A0A0K8UZH7   H9XVM7   T1PJ65   A0A0C9RDQ4   A0A0T6BG36   B4NHJ7   A0A1D2N376   A0A034WWY5   A0A2S2PN28   A0A0K8U2F3   A0A1A9WKY9   B3P9V1   A0A0J9S0Q9   B4IL88   Q9XYM0  

PDB

2EYZ     E-value=1.0836e-20,     Score=240

KEGG

101745959    K04438 proto-oncogene C-crk | (RefSeq) adapter molecule Crk

GO

GO:0016021   GO:0055085   GO:0007298   GO:0006911   GO:0046330   GO:0030971   GO:0046529   GO:0048010   GO:0048013   GO:0043087   GO:0032956   GO:0007520  

Length:

141

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.16389

Exp number, first 60 AAs:

0.00088

Total prob of N-in:

0.07022

outside

1  -  141

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0

CSRT

0

Interpretation

Uncertain