SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO16663
Annotation
PREDICTED:_uncharacterized_protein_LOC100101190_isoform_X1_[Bombyx_mori]
Full name
DNA-(apurinic or apyrimidinic site) lyase      
Location in the cell
PlasmaMembrane   Reliability : 1.619
 

Sequence

CDS
ATGTTTGTGGTATCTCCTCATATACGCCAGGAATGGAAATGTATGGCTACTCTGATTGCAAGATTTTCAAATAAACCCACATCATCCGAGGTTCTAACAGCCTATTTAACTCAGTGTAACGAACCACCTTGGACTTCTTATTTTGTAAAGTACAGTTATGTGAAAGATGATCAGTTTGGAATGTCAAATTTTAATTGGAAGGTTGGTAATTCCAACTATCAAATATTAAGAACTGGTTGTTTTCCATATATAAAATATCACTGTTCTAGAAAAAAGGCAGAAGACTTAAATATGTCAGATAAATTTATGAGAATTATAAAGGTTGCAAATTTAGGTATGTAA
Protein
MFVVSPHIRQEWKCMATLIARFSNKPTSSEVLTAYLTQCNEPPWTSYFVKYSYVKDDQFGMSNFNWKVGNSNYQILRTGCFPYIKYHCSRKKAEDLNMSDKFMRIIKVANLGM

Summary

Catalytic Activity
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
Similarity
Belongs to the complex I 49 kDa subunit family.
Belongs to the DNA repair enzymes AP/ExoA family.
EC Number
4.2.99.18
EMBL
KQ459220    KPJ02847.1    KQ459984    KPJ18967.1    NWSH01000683    PCG74813.1    + More
ODYU01002932    SOQ41048.1    JTDY01001004    KOB75142.1    AGBW02012778    OWR44460.1    RSAL01000293    RVE42876.1    GEZM01062047    JAV70089.1    GEZM01062046    JAV70091.1    NNAY01000071    OXU31279.1    KK853153    KDR10553.1    KQ971354    KYB26580.1    NEVH01006756    PNF36448.1    PYGN01000580    PSN43884.1    LJIG01009625    KRT82706.1    KK107245    QOIP01000014    EZA54506.1    RLU14821.1    GBYB01014251    JAG84018.1    GECZ01008811    JAS60958.1    KQ982729    KYQ51577.1    AAAB01008847    EAU77223.3    GGFK01012948    MBW46269.1    APCN01001005    GEDC01016555    GEDC01013341    JAS20743.1    JAS23957.1    KQ981940    KYN32744.1    GBHO01031273    GBHO01011758    GBRD01004528    JAG12331.1    JAG31846.1    JAG61293.1    GDHF01028799    JAI23515.1    GDHF01010523    JAI41791.1    ADTU01020800    KQ976529    KYM81725.1    KQ978946    KYN27401.1    AE014297    AAN13890.2    BT032967    ACD99531.1    GL888334    EGI62585.1    AXCN02001373    DS232152    EDS36191.1    ABLF02019454    GFWV01019829    MAA44557.1    ADMH02001172    ETN63842.1    KQ978231    KYM96163.1    ATLV01025101    KE525369    KFB52162.1    GAMD01002975    JAA98615.1    ABLF02019452    GFXV01003063    MBW14868.1    CM012442    RVE71806.1    JXJN01022584    AXCM01009391    KK854413    PTY15653.1    KQ434810    KZC06737.1    CH477759    EAT36539.1    GL440609    EFN65695.1    DS235442    EEB15786.1    KQ042192    KKF18153.1    LNIX01000006    OXA52816.1    GL453868    EFN75376.1    CAAE01014555    CAF98367.1    AFYH01123882    DS469534    EDO45650.1    GDAI01002339    JAI15264.1    JW874163    AFP06680.1    AERX01005350   
Pfam
PF15031   DUF4528        + More
PF00346   Complex1_49kDa
PF03372   Exo_endo_phos
Interpro
IPR029245   DUF4528        + More
IPR022885   NDH1_su_D/H       
IPR001135   NADH_Q_OxRdtase_suD       
IPR014029   NADH_UbQ_OxRdtase_49kDa_CS       
IPR029014   NiFe-Hase_large       
IPR038290   NADH_Q_OxRdtase_suD_sf       
IPR020848   AP_endonuclease_F1_CS       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR005135   Endo/exonuclease/phosphatase       
IPR004808   AP_endonuc_1       
IPR020847   AP_endonuclease_F1_BS       
SUPFAM
SSF56762   SSF56762        + More
SSF56219   SSF56219       
Gene 3D

Ontologies

Topology

Length:
113
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.00137
Exp number, first 60 AAs:
0.0007
Total prob of N-in:
0.17357
outside
1  -  113
 
 

Population Genetic Test Statistics

Pi
0
Theta
0
Tajima's D
0
CLR
0
CSRT
0
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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