Gene

KWMTBOMO16663

Annotation

PREDICTED:_uncharacterized_protein_LOC100101190_isoform_X1_[Bombyx_mori]

Location

Bomo_Scaf078(+):28646-29250      View in EpiBrowser

Full name

DNA-(apurinic or apyrimidinic site) lyase      

Location in the cell

PlasmaMembrane   Reliability : 1.619

CDS

ATGTTTGTGGTATCTCCTCATATACGCCAGGAATGGAAATGTATGGCTACTCTGATTGCAAGATTTTCAAATAAACCCACATCATCCGAGGTTCTAACAGCCTATTTAACTCAGTGTAACGAACCACCTTGGACTTCTTATTTTGTAAAGTACAGTTATGTGAAAGATGATCAGTTTGGAATGTCAAATTTTAATTGGAAGGTTGGTAATTCCAACTATCAAATATTAAGAACTGGTTGTTTTCCATATATAAAATATCACTGTTCTAGAAAAAAGGCAGAAGACTTAAATATGTCAGATAAATTTATGAGAATTATAAAGGTTGCAAATTTAGGTATGTAA

Protein

MFVVSPHIRQEWKCMATLIARFSNKPTSSEVLTAYLTQCNEPPWTSYFVKYSYVKDDQFGMSNFNWKVGNSNYQILRTGCFPYIKYHCSRKKAEDLNMSDKFMRIIKVANLGM

Catalytic Activity

The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

Similarity

Belongs to the complex I 49 kDa subunit family.
Belongs to the DNA repair enzymes AP/ExoA family.

Uniprot

A0A194QBK8   A0A194RN77   A0A2A4JTL9   A0A2H1VJQ0   A0A0L7LI69   A0A212ESJ4   + More
A0A3S2LRI7   A0A1Y1L8Q4   A0A1Y1LB50   A0A232FL96   A0A067QMQ1   K7IY11   A0A139WF30   A0A2J7R6I9   A0A2P8YI59   A0A0T6B5T1   A0A1W4WY99   A0A026WFQ6   A0A0C9S0V9   A0A1B6GEU7   A0A182PM66   A0A088AFK1   A0A151WUY8   A0A182KFB2   A0NCR8   A0A2M4AZQ4   A0A182V7W2   A0A182X5B4   A0A182TN49   A0A182I9M1   A0A1B6D519   A0A195EXY9   A0A0A9WY25   A0A0K8UAY1   A0A0K8VSC5   A0A182J5B4   A0A158NMT3   A0A195BC03   A0A151JM52   A4V381   A0A182XY40   B3DNH9   A0A182FIL7   F4WTC2   A0A182QJI2   A0A182RJ19   B0WWT0   J9JRW7   A0A293MFV5   W5JHJ8   A0A1I8N5H7   A0A195C7N9   A0A182SRP4   A0A3Q3JA43   A0A3P9GYR6   A0A084WPL8   A0A3B5KE75   A0A1A9WY09   T1DND8   X1WJT8   A0A182VVB4   A0A3P9KFJ5   A0A2H8TNN0   A0A182N0Y9   A0A3S2Q6P1   A0A1B0BYC9   A0A182MPF4   A0A1I8NYZ6   A0A2R7W7G0   A0A3B3DWC1   H2LQW6   A0A3Q3VR30   A0A154P4F0   Q16Q67   A0A1S4FTD6   E2ALJ3   E0VQY0   A0A3B4YLD5   A0A1A9YLP5   A0A3B5KHR3   A0A0F8BV48   A0A3Q3L5E8   A0A3B4TYB8   A0A3B4GCR5   A0A3Q2W3W9   A0A3Q4MV60   A0A3P9D7C7   A0A226E833   A0A3Q3D9T2   E2C9N7   A0A3Q3DH82   Q4SLW5   M3XKR2   A0A3P8PY78   H3AWY9   A7RSK0   A0A0K8TLP7   V9L4Z7   A0A3Q1HYR5   I3KEC0  

EC Number

4.2.99.18

Pubmed

26354079    26227816    22118469    28004739    28648823    24845553    + More
20075255    18362917    19820115    29403074    24508170    30249741    12364791    14747013    17210077    25401762    21347285    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    25244985    21719571    20920257    23761445    25315136    17554307    24438588    21551351    29451363    17510324    20798317    20566863    25835551    25186727    15496914    9215903    17615350    26369729    24402279   

EMBL

KQ459220    KPJ02847.1    KQ459984    KPJ18967.1    NWSH01000683    PCG74813.1    + More
ODYU01002932    SOQ41048.1    JTDY01001004    KOB75142.1    AGBW02012778    OWR44460.1    RSAL01000293    RVE42876.1    GEZM01062047    JAV70089.1    GEZM01062046    JAV70091.1    NNAY01000071    OXU31279.1    KK853153    KDR10553.1    KQ971354    KYB26580.1    NEVH01006756    PNF36448.1    PYGN01000580    PSN43884.1    LJIG01009625    KRT82706.1    KK107245    QOIP01000014    EZA54506.1    RLU14821.1    GBYB01014251    JAG84018.1    GECZ01008811    JAS60958.1    KQ982729    KYQ51577.1    AAAB01008847    EAU77223.3    GGFK01012948    MBW46269.1    APCN01001005    GEDC01016555    GEDC01013341    JAS20743.1    JAS23957.1    KQ981940    KYN32744.1    GBHO01031273    GBHO01011758    GBRD01004528    JAG12331.1    JAG31846.1    JAG61293.1    GDHF01028799    JAI23515.1    GDHF01010523    JAI41791.1    ADTU01020800    KQ976529    KYM81725.1    KQ978946    KYN27401.1    AE014297    AAN13890.2    BT032967    ACD99531.1    GL888334    EGI62585.1    AXCN02001373    DS232152    EDS36191.1    ABLF02019454    GFWV01019829    MAA44557.1    ADMH02001172    ETN63842.1    KQ978231    KYM96163.1    ATLV01025101    KE525369    KFB52162.1    GAMD01002975    JAA98615.1    ABLF02019452    GFXV01003063    MBW14868.1    CM012442    RVE71806.1    JXJN01022584    AXCM01009391    KK854413    PTY15653.1    KQ434810    KZC06737.1    CH477759    EAT36539.1    GL440609    EFN65695.1    DS235442    EEB15786.1    KQ042192    KKF18153.1    LNIX01000006    OXA52816.1    GL453868    EFN75376.1    CAAE01014555    CAF98367.1    AFYH01123882    DS469534    EDO45650.1    GDAI01002339    JAI15264.1    JW874163    AFP06680.1    AERX01005350   

Proteomes

UP000053268    UP000053240    UP000218220    UP000037510    UP000007151    UP000283053    + More
UP000215335    UP000027135    UP000002358    UP000007266    UP000235965    UP000245037    UP000192223    UP000053097    UP000279307    UP000075885    UP000005203    UP000075809    UP000075881    UP000007062    UP000075903    UP000076407    UP000075902    UP000075840    UP000078541    UP000075880    UP000005205    UP000078540    UP000078492    UP000000803    UP000076408    UP000069272    UP000007755    UP000075886    UP000075900    UP000002320    UP000007819    UP000000673    UP000095301    UP000078542    UP000075901    UP000261600    UP000265200    UP000030765    UP000005226    UP000091820    UP000075920    UP000265180    UP000075884    UP000092460    UP000075883    UP000095300    UP000261560    UP000001038    UP000261620    UP000076502    UP000008820    UP000000311    UP000009046    UP000261360    UP000092443    UP000261640    UP000261420    UP000261460    UP000264840    UP000261580    UP000265160    UP000198287    UP000264820    UP000008237    UP000008672    UP000265100    UP000001593    UP000265040    UP000005207   

PRIDE

B3DNH9   

Pfam

PF15031   DUF4528        + More
PF00346   Complex1_49kDa
PF03372   Exo_endo_phos

Interpro

IPR029245   DUF4528        + More
IPR022885   NDH1_su_D/H       
IPR001135   NADH_Q_OxRdtase_suD       
IPR014029   NADH_UbQ_OxRdtase_49kDa_CS       
IPR029014   NiFe-Hase_large       
IPR038290   NADH_Q_OxRdtase_suD_sf       
IPR020848   AP_endonuclease_F1_CS       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR005135   Endo/exonuclease/phosphatase       
IPR004808   AP_endonuc_1       
IPR020847   AP_endonuclease_F1_BS       

SUPFAM

SSF56762   SSF56762        + More
SSF56219   SSF56219       

Gene 3D

1.10.645.20     3.60.10.10    

ProteinModelPortal

A0A194QBK8   A0A194RN77   A0A2A4JTL9   A0A2H1VJQ0   A0A0L7LI69   A0A212ESJ4   + More
A0A3S2LRI7   A0A1Y1L8Q4   A0A1Y1LB50   A0A232FL96   A0A067QMQ1   K7IY11   A0A139WF30   A0A2J7R6I9   A0A2P8YI59   A0A0T6B5T1   A0A1W4WY99   A0A026WFQ6   A0A0C9S0V9   A0A1B6GEU7   A0A182PM66   A0A088AFK1   A0A151WUY8   A0A182KFB2   A0NCR8   A0A2M4AZQ4   A0A182V7W2   A0A182X5B4   A0A182TN49   A0A182I9M1   A0A1B6D519   A0A195EXY9   A0A0A9WY25   A0A0K8UAY1   A0A0K8VSC5   A0A182J5B4   A0A158NMT3   A0A195BC03   A0A151JM52   A4V381   A0A182XY40   B3DNH9   A0A182FIL7   F4WTC2   A0A182QJI2   A0A182RJ19   B0WWT0   J9JRW7   A0A293MFV5   W5JHJ8   A0A1I8N5H7   A0A195C7N9   A0A182SRP4   A0A3Q3JA43   A0A3P9GYR6   A0A084WPL8   A0A3B5KE75   A0A1A9WY09   T1DND8   X1WJT8   A0A182VVB4   A0A3P9KFJ5   A0A2H8TNN0   A0A182N0Y9   A0A3S2Q6P1   A0A1B0BYC9   A0A182MPF4   A0A1I8NYZ6   A0A2R7W7G0   A0A3B3DWC1   H2LQW6   A0A3Q3VR30   A0A154P4F0   Q16Q67   A0A1S4FTD6   E2ALJ3   E0VQY0   A0A3B4YLD5   A0A1A9YLP5   A0A3B5KHR3   A0A0F8BV48   A0A3Q3L5E8   A0A3B4TYB8   A0A3B4GCR5   A0A3Q2W3W9   A0A3Q4MV60   A0A3P9D7C7   A0A226E833   A0A3Q3D9T2   E2C9N7   A0A3Q3DH82   Q4SLW5   M3XKR2   A0A3P8PY78   H3AWY9   A7RSK0   A0A0K8TLP7   V9L4Z7   A0A3Q1HYR5   I3KEC0  

KEGG

100101190    no KO assigned | (RefSeq) Bmp-005136; uncharacterized LOC100101190

GO

GO:0016021   GO:0016651   GO:0048038   GO:0051287   GO:0140078   GO:0006281   GO:0046872   GO:0004519   GO:0003677  

PANTHER

PTHR34651   PTHR22748  

Length:

113

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00137

Exp number, first 60 AAs:

0.0007

Total prob of N-in:

0.17357

outside

1  -  113

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0

CSRT

0

Interpretation

Uncertain