Gene

KWMTBOMO16578  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005570

Annotation

PREDICTED:_lethal(2)_giant_larvae_protein_isoform_X2_[Bombyx_mori]

Location

Bomo_Scaf025(-):11638-33345      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 1.23

CDS

ATGCAGAACTGCCCAGAGGATTACAAAGTTAACCCAGGCGCGGTGGAGTCTGTATACGAACACCCTAAGACTCCTACACGTATTCTGATCGGATACAACCGAGGACTGGCCGTGCTTTGGGACCGGGAGGCTGCGGCTCCCACACATACATTTGTTTCGAATCAACAGCTTGAAAGCTTATGCTGGAATGACGATGGCGAGCACTTCACATCATCGCACAACGACGGTTCGTACGTGACGTGGGAGGTGGCCGGCGCCTCCAGCGACCGACCCCTGAAGGAGCCCGTCACGCCCTACGGACCCTACCCTTGTAAGGCGATCACCAAGATCCTGAACAGGACTAGCGTTGATGGAGAGGACATCACTATATTTGCCGGTGGCATGCCCAGAGCTTCGTACTCCGACAAGTACACGGTTACCGTGCAGCAGGGCGAGAAACATGTGGCCTTCGATTTCACGAGCCGGGTGATAGATTTGTTCACAACGACTCCCGTGCCCCCGGACGGCGCGCCGCTGCAGGAGGAGCAGCCCGACACCCCGGCCCTCGTACAGGTGCAAGCGGTCAACCAGGTCGCCGCCGCTTTGGTGGTCCTGGCGGAAGAGGAGCTGGTGGTGATAGACCTATGCGACGCGCGCTGGCGGCCGCTGCGGCTGCCGTACCTGGTGTCGGTGCACGCGTCCGCCGTCACCACGGCGCAGCTGGCCGACGGCGTGGCGCCCGCAGTCTACGACAACATCGTCGCCGCGGGTCAACAACAAACGGAGAATCAATACTCGGAGAGTCCGTGGCCGATATCCGGTGGAGTGGTGGAGACGGCGGAGCTGACCGACAGACAGGTGCTGCTCACGGGGCACGAGGACGGCTCCGTGCGGTTCTGGGACGTGACCGGCGTCGCCATGACCCCCCTGTACAAGTACACCACCGCGCAGCTGTTCAGTGGTGAAGAACTTGGTGAAAACAACGACAGTCAGACCACAGATGAAGAGGAGTGGCCTCCCTTCAGGCGAGTCGGCACCTTCGACCCGTACAGCGACGACCCCCGGCTCGCGGTCAAAAAGGTTATATTGTGCCCGTTATCTGGAATGCTCACCATCGGCGGAGCCGCCGGCCATATTGTCATAGCCAGTCTCAAGACCTCTCCGAGCACCACCGAAGTCAAGTCGGTGTCAGTGAATATAGTGTCAGACAGAGACGGCTTCGTGTGGAAGGGACACGGGCAGCTCACGTTGAGGGCCGGCACGCACACCTTCCCGCAGGGATATCAGGCGACCTCGGTGGTGCAGCTGCAGCCCCCGGCGGCCGTGACGTCACTGAGCGCGCAGTGGGAGTGGGGCGTGGTGTGCGCCGGCACCGCGCACGGGCTGGCGCTGGTGGACGCGCTGGGCCCGGCGCCCGCGCCGCTGCTGCATAAGTGCACGCTCAACCCGCACGATCACGGATCCGGTGACACGCCAATATCGAGAAGAAAGTCCTTCAAGAAATCCTTGAGAGAGTCATTCAGGAGGCTTCGTAAAGGACGTTCACAACGGCGACAGACGACATCGAATCCCACCTCGCCCACACAACCGATTCCGAAGAAGCCAATTGACAAAGCCGCCTCGGAAACGGACGCGGAAATCAAACCGATCGAGCGCGCGGTGGAGGCCCGCTCCACGGACGACGCCTACGGCTCGATGGTGCGCTGCCTGTACTTCGCGAGGACCTTCCTCATCAATACCCAGCAATCGACGCCGACGCTATGGGCCGGCACGAACAACGGCACTGTGTACGCCTTCACGCTGCACGTGCCCAACACTAACAAACGGAAAGAGGAACCAGTAACGTGTCAGCTAGCGAAAGAAATACAGTTGAAGCACAGGGCCCCGGTCATAGGGATCACAGTACTCGACGGCGCCTCCGTACCTCTGCCCGATCCCCTAGAGGTGGAACGAGGTGTGTCCCCGCTACCGGAGCCGGGTACACATCGTGTGGTCATCACGTCGGAGGAACAGTTCAAGATATTCACTCTGCCTTCGTTGAAACCGCACAACAAGTACAAGCTGACCGCGCACGAGGGCGCTCGGGTTCGGCGCACGGCGTGGTCGCAGTTCTCGTGCGGCGCGCACCGGGAGTGGTGCTTGCTGTGCCTCACCAACCTCGGCGACTGCCTCGTGCTCAGCCCGGAGCTGCGCCGCCAGCTCAACGCCGCCGCCGTCAGGAAGGAGGACATCAATGGGATTTCGAGTTTATGTTTCTCGAAGCGAGGAGAAGCTCTCTACCTGCACTCGTCTTCCGAATTACAACGGATTACTTTATCTGCTACGAAGGTGACGATCGCGGAGTGCCACGTGCTGCTGGCGCCCTGGGCGGCCGCGCTGCGGGGACCCGCGCCGGAGCCGCCGCTCACCAACGGGGAGCATAAGGTAGACTGTGTACTCATAGTGGGATTGACGATACAGGAAGAGGTGCCGGAGACAGCTCATGACGTCACGGCGGCCTCGGCGGACATCACCGTGGACAGCGTGCGCGACCACACCAGCGCGGAGCACCCGCCCGAACTCAACATCAACTTACAAAACACGCAAGTGAATACGAGTTCGATGGTAATAAAGACAACGACACGCACGACCGTGAACGAGACCAACGCGGACGGCACCACCACCACCACCACGACCAGCACTAACAACGCCAACGAGAACAATTTGTGTTTGTTTGACGGGCGCTTTATGTTTTTGTTCGTAGTCCTAGAGCACAGTCGCGAGGAGGGAGTCATCACCCGCATCGAGACGGGAACCGTGACGGTGCCGGCCGGCACAGATCCGAAGCTGATCCTCGAGATGTTTGATCGACAACGGTCCCCCCTGGCGGTCCCCGTGCCGCCCCCCACTGACGCGCACTGA

Protein

MQNCPEDYKVNPGAVESVYEHPKTPTRILIGYNRGLAVLWDREAAAPTHTFVSNQQLESLCWNDDGEHFTSSHNDGSYVTWEVAGASSDRPLKEPVTPYGPYPCKAITKILNRTSVDGEDITIFAGGMPRASYSDKYTVTVQQGEKHVAFDFTSRVIDLFTTTPVPPDGAPLQEEQPDTPALVQVQAVNQVAAALVVLAEEELVVIDLCDARWRPLRLPYLVSVHASAVTTAQLADGVAPAVYDNIVAAGQQQTENQYSESPWPISGGVVETAELTDRQVLLTGHEDGSVRFWDVTGVAMTPLYKYTTAQLFSGEELGENNDSQTTDEEEWPPFRRVGTFDPYSDDPRLAVKKVILCPLSGMLTIGGAAGHIVIASLKTSPSTTEVKSVSVNIVSDRDGFVWKGHGQLTLRAGTHTFPQGYQATSVVQLQPPAAVTSLSAQWEWGVVCAGTAHGLALVDALGPAPAPLLHKCTLNPHDHGSGDTPISRRKSFKKSLRESFRRLRKGRSQRRQTTSNPTSPTQPIPKKPIDKAASETDAEIKPIERAVEARSTDDAYGSMVRCLYFARTFLINTQQSTPTLWAGTNNGTVYAFTLHVPNTNKRKEEPVTCQLAKEIQLKHRAPVIGITVLDGASVPLPDPLEVERGVSPLPEPGTHRVVITSEEQFKIFTLPSLKPHNKYKLTAHEGARVRRTAWSQFSCGAHREWCLLCLTNLGDCLVLSPELRRQLNAAAVRKEDINGISSLCFSKRGEALYLHSSSELQRITLSATKVTIAECHVLLAPWAAALRGPAPEPPLTNGEHKVDCVLIVGLTIQEEVPETAHDVTAASADITVDSVRDHTSAEHPPELNINLQNTQVNTSSMVIKTTTRTTVNETNADGTTTTTTTSTNNANENNLCLFDGRFMFLFVVLEHSREEGVITRIETGTVTVPAGTDPKLILEMFDRQRSPLAVPVPPPTDAH

Uniprot

A0A2H1VVV8   A0A194QB38   A0A212EP80   D0ABA2   A0A194QRZ2   A0A1W4WVL3   + More
A0A1Y1M6N1   A0A1Y1M8D0   A0A088ATY3   A0A2A3EHA3   D6WYA8   A0A139WE14   A0A026WN55   A0A2J7Q3S4   E2ARD1   A0A0L7QPQ1   A0A2J7Q3P7   A0A3L8DEL2   A0A195CTM4   A0A0T6BEC4   A0A154PAT3   F4WJ09   A0A151WX96   A0A0C9RCT4   A0A195BP13   A0A158NTR4   A0A0C9R9G3   A0A0C9RCT9   N6U4D3   A0A0C9R0B9   A0A1B6CVU9   U4UGL0   A0A151JMZ0   A0A1B6CIZ4   A0A195FPM1   A0A1B6CQA4   A0A0M9A937   E2B5S5   A0A232F9W9   K7IZ75   A0A0N0BD23   A0A0P4VYT6   A0A023F356   A0A069DZP9   T1HCU9   A0A224X621   A0A0V0G3S9   A0A0A9Z0Y7   A0A0A9YQZ0   A0A1W7RA96   A0A087TSG8   A0A1B6D4V8   A0A2S2R2K4   A0A2H8TZ75   A0A2S2PBF4   J9JXB1   E0VQS5   A0A2R7W095   A0A3R7LXJ7   V4AVR9   C3Z7S5   E9GZG8   A0A210QA96   A0A1L8DW03   A0A1L8DVZ1   W5MCA3   W5MC81   A0A1L8DW02   A0A1W4Z6H8   A0A341C4L4   F6Z9W6   A0A2Y9M323   A0A2Y9M5S3   A0A341C3M7   K1PU46   A0A2Y9MGN2   A0A2Y9M3X8   A0A340WMZ0   A0A2Y9T6I3   A0A2D0PVN6   E2RPS3   A0A2Y9MBF5   A0A383ZGJ2   A0A3Q7TJA6   E1BMF9   E7FD67   M7BTX0   A0A2K5HSX6   F1QPI4   A0A287A6Z8   A0A2K6PHA5   A0A212DAI1   F7CIU8   A0A3Q2HGF7  

Pubmed

26354079    22118469    28004739    18362917    19820115    24508170    + More
20798317    30249741    21719571    21347285    23537049    28648823    20075255    27129103    25474469    26334808    25401762    26823975    20566863    23254933    18563158    21292972    28812685    17495919    22992520    16341006    19393038    23594743    23624526    25362486    19892987   

EMBL

ODYU01004452    SOQ44334.1    KQ459232    KPJ02644.1    AGBW02013517    OWR43276.1    + More
FP102341    CBH09297.1    KQ461155    KPJ08288.1    GEZM01042811    JAV79576.1    GEZM01042812    GEZM01042810    JAV79577.1    KZ288255    PBC30662.1    KJ434293    KQ971356    AHY24027.1    EFA09125.1    KYB26183.1    KK107148    EZA57460.1    NEVH01019065    PNF23209.1    GL442047    EFN64009.1    KQ414806    KOC60618.1    PNF23211.1    QOIP01000009    RLU18875.1    KQ977279    KYN04048.1    LJIG01001374    KRT85566.1    KQ434846    KZC08328.1    GL888181    EGI65779.1    KQ982673    KYQ52436.1    GBYB01010942    JAG80709.1    KQ976435    KYM87099.1    ADTU01026117    GBYB01009562    JAG79329.1    GBYB01010947    JAG80714.1    APGK01039896    KB740975    ENN76455.1    GBYB01009564    JAG79331.1    GEDC01019629    JAS17669.1    KB632186    ERL89741.1    KQ978878    KYN27856.1    GEDC01023891    GEDC01022956    GEDC01002554    JAS13407.1    JAS14342.1    JAS34744.1    KQ981382    KYN42351.1    GEDC01021619    JAS15679.1    KQ435724    KOX78389.1    GL445887    EFN88894.1    NNAY01000642    OXU27238.1    KQ435881    KOX69842.1    GDKW01001880    JAI54715.1    GBBI01003141    JAC15571.1    GBGD01000260    JAC88629.1    ACPB03000213    GFTR01008501    JAW07925.1    GECL01003493    JAP02631.1    GBHO01038923    GBHO01038922    GBHO01021108    GBHO01021059    GBHO01017046    GBHO01011663    GBHO01011660    GBHO01011657    GBHO01011656    GBHO01011655    GBHO01006591    GBHO01006590    GBRD01014279    GBRD01014278    GDHC01018735    JAG04681.1    JAG04682.1    JAG22496.1    JAG22545.1    JAG26558.1    JAG31941.1    JAG31944.1    JAG31947.1    JAG31948.1    JAG31949.1    JAG37013.1    JAG37014.1    JAG51547.1    JAP99893.1    GBHO01023873    GBHO01018251    GBHO01018222    GBHO01017047    GBHO01017045    GBHO01017044    GBHO01017042    GBHO01011661    GBHO01011659    GBHO01011654    GBHO01006592    GBHO01001777    GBRD01017551    GBRD01010369    GDHC01010587    JAG19731.1    JAG25353.1    JAG25382.1    JAG26557.1    JAG26559.1    JAG26560.1    JAG26562.1    JAG31943.1    JAG31945.1    JAG31950.1    JAG37012.1    JAG41827.1    JAG48276.1    JAQ08042.1    GFAH01000325    JAV48064.1    KK116537    KFM68057.1    GEDC01016600    JAS20698.1    GGMS01015013    MBY84216.1    GFXV01007405    MBW19210.1    GGMR01014093    MBY26712.1    ABLF02035340    DS235440    EEB15731.1    KK854212    PTY13166.1    QCYY01002835    ROT67186.1    KB200521    ESP01458.1    GG666591    EEN51430.1    GL732577    EFX75147.1    NEDP02004422    OWF45664.1    GFDF01003478    JAV10606.1    GFDF01003477    JAV10607.1    AHAT01013466    AHAT01013467    AHAT01013468    AHAT01013469    GFDF01003476    JAV10608.1    JH818286    EKC19885.1    AAEX03003715    BX649356    BX649547    KB528467    EMP35543.1    AEMK02000083    MKHE01000005    OWK15241.1   

Proteomes

UP000053268    UP000007151    UP000053240    UP000192223    UP000005203    UP000242457    + More
UP000007266    UP000053097    UP000235965    UP000000311    UP000053825    UP000279307    UP000078542    UP000076502    UP000007755    UP000075809    UP000078540    UP000005205    UP000019118    UP000030742    UP000078492    UP000078541    UP000053105    UP000008237    UP000215335    UP000002358    UP000015103    UP000054359    UP000007819    UP000009046    UP000283509    UP000030746    UP000001554    UP000000305    UP000242188    UP000018468    UP000192224    UP000252040    UP000002280    UP000248483    UP000005408    UP000265300    UP000248484    UP000221080    UP000002254    UP000261681    UP000286640    UP000009136    UP000000437    UP000031443    UP000233080    UP000008227    UP000233200    UP000002281   

Pfam

PF08366   LLGL        + More
PF00096   zf-C2H2
PF00400   WD40
PF08596   Lgl_C
PF12894   ANAPC4_WD40
PF09457   RBD-FIP

Interpro

IPR036322   WD40_repeat_dom_sf        + More
IPR013087   Znf_C2H2_type       
IPR019775   WD40_repeat_CS       
IPR036236   Znf_C2H2_sf       
IPR001680   WD40_repeat       
IPR017986   WD40_repeat_dom       
IPR012934   Znf_AD       
IPR013577   LLGL2       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR000664   Lethal2_giant       
IPR013905   Lgl_C_dom       
IPR024977   Apc4_WD40_dom       
IPR019018   Rab-bd_FIP-RBD       
IPR037245   FIP-RBD_C_sf       

SUPFAM

SSF50978   SSF50978        + More
SSF57667   SSF57667       
SSF144270   SSF144270       

Gene 3D

2.130.10.10    

ProteinModelPortal

A0A2H1VVV8   A0A194QB38   A0A212EP80   D0ABA2   A0A194QRZ2   A0A1W4WVL3   + More
A0A1Y1M6N1   A0A1Y1M8D0   A0A088ATY3   A0A2A3EHA3   D6WYA8   A0A139WE14   A0A026WN55   A0A2J7Q3S4   E2ARD1   A0A0L7QPQ1   A0A2J7Q3P7   A0A3L8DEL2   A0A195CTM4   A0A0T6BEC4   A0A154PAT3   F4WJ09   A0A151WX96   A0A0C9RCT4   A0A195BP13   A0A158NTR4   A0A0C9R9G3   A0A0C9RCT9   N6U4D3   A0A0C9R0B9   A0A1B6CVU9   U4UGL0   A0A151JMZ0   A0A1B6CIZ4   A0A195FPM1   A0A1B6CQA4   A0A0M9A937   E2B5S5   A0A232F9W9   K7IZ75   A0A0N0BD23   A0A0P4VYT6   A0A023F356   A0A069DZP9   T1HCU9   A0A224X621   A0A0V0G3S9   A0A0A9Z0Y7   A0A0A9YQZ0   A0A1W7RA96   A0A087TSG8   A0A1B6D4V8   A0A2S2R2K4   A0A2H8TZ75   A0A2S2PBF4   J9JXB1   E0VQS5   A0A2R7W095   A0A3R7LXJ7   V4AVR9   C3Z7S5   E9GZG8   A0A210QA96   A0A1L8DW03   A0A1L8DVZ1   W5MCA3   W5MC81   A0A1L8DW02   A0A1W4Z6H8   A0A341C4L4   F6Z9W6   A0A2Y9M323   A0A2Y9M5S3   A0A341C3M7   K1PU46   A0A2Y9MGN2   A0A2Y9M3X8   A0A340WMZ0   A0A2Y9T6I3   A0A2D0PVN6   E2RPS3   A0A2Y9MBF5   A0A383ZGJ2   A0A3Q7TJA6   E1BMF9   E7FD67   M7BTX0   A0A2K5HSX6   F1QPI4   A0A287A6Z8   A0A2K6PHA5   A0A212DAI1   F7CIU8   A0A3Q2HGF7  

PDB

6N8S     E-value=8.61845e-166,     Score=1502

KEGG

101742621    K06094 lethal(2) giant larvae protein | (RefSeq) lethal(2) giant larvae protein

PATHWAY

04391    Hippo signaling pathway - fly - Bombyx mori (domestic silkworm)

GO

GO:0003676   GO:0008270   GO:0005634   GO:0005737   GO:0032878   GO:0008593   GO:0030864   GO:0030866   GO:0005096   GO:0005886   GO:0017137   GO:0045159   GO:0019905   GO:0051294   GO:0016021   GO:0019901   GO:0065003   GO:0048919   GO:0003407   GO:0016323   GO:0030031   GO:0005515   GO:0046872   GO:0004930   GO:0006915   GO:0016651   GO:0046835   GO:0006281   GO:0006259  

Length:

959

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.45135

Exp number, first 60 AAs:

0.0001

Total prob of N-in:

0.02028

outside

1  -  959

 

 

Pi

21.027004

Theta

24.009066

Tajima's D

-1.023903

CLR

0.064906

CSRT

0.131893405329734

Interpretation

Uncertain