Gene

KWMTBOMO16575

Pre Gene Modal

BGIBMGA014076

Annotation

Trypsin-7_[Papilio_xuthus]

Location

Bomo_Scaf023(-):48483-54545      View in EpiBrowser

Full name

Trypsin 3A1       + More
Trypsin-7      
Trypsin-1      
Trypsin-2      
Trypsin 5G1      
Trypsin-3      
Trypsin      

Alternative Name

Antryp1
Antryp2

Location in the cell

PlasmaMembrane   Reliability : 2.188

CDS

ATGTATAGAGCTCCAAAACTAATTATATTTATATTTGGGTTCAAGATTAAATGGAGAATCGTTGGCGGGGACCAAGTTAGCATCAAACAAATTCCCTATCAAGTACTCTATGGTATGTATTGCGGTGGAGTTCTGATAGCACCAGACTGGGTTCTCACGGCTGCTCACTGCAAAGACAAAAGCGACTTCATCCTAGCCGGTTCGACATACAGGAGTAGGGCAACTCGATATCCCGTTTGCGCTCACTTCTTTCATCCGTTGTGGAACTCGTCTTCAAAACTCCACAGTCATGACTATGATTATCAACTGCTCTTGTTGGAAGTGGCAGTGCCAGTGACTATGGAAAGTAGACCTGTTGCTATAGGCCTTGCTAACGACATCCAGCCAGGGGCTTTGATCTCGGTCAGCGGTTGGGGCCACATCGAGTATAAGAGCAGGCTGATGCAAGACGTGGTTCGTCGGGCGTATATTCCTGTCATCAGTTATTACGAGTGCAAATCTTTACCGCTGCCAAACTACAGGAATATTACGACTAGAATGTTCTGCGCCGGCTACAAGAATGGAACTAAGGATTCATGTCAAGGTGACTCCGGTAGTCCTGCTATTATCAAAGGAAAGCTGGTTGGCATAGTGTCCTTCGGCGTCGGCTGTGCAGTGAAGAACCAGCCAGGGGTTTATACCGACGTGCCTATCGCCAGAGCCTGGATACGATCAGTGACGGGTCTACCGCTTTGA

Protein

MYRAPKLIIFIFGFKIKWRIVGGDQVSIKQIPYQVLYGMYCGGVLIAPDWVLTAAHCKDKSDFILAGSTYRSRATRYPVCAHFFHPLWNSSSKLHSHDYDYQLLLLEVAVPVTMESRPVAIGLANDIQPGALISVSGWGHIEYKSRLMQDVVRRAYIPVISYYECKSLPLPNYRNITTRMFCAGYKNGTKDSCQGDSGSPAIIKGKLVGIVSFGVGCAVKNQPGVYTDVPIARAWIRSVTGLPL

Description

Major function may be to aid in digestion of the blood meal.
Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female.

Catalytic Activity

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

Similarity

Belongs to the peptidase S1 family.

Keywords

Alternative splicing   Complete proteome   Digestion   Disulfide bond   Hydrolase   Protease   Reference proteome   Secreted   Serine protease   Signal   Zymogen  

Feature

propeptide  Activation peptide
chain  Trypsin 3A1
splice variant  In isoform A.

Uniprot

A0A2H1W9P5   A0A2W1BG09   A0A2A4K562   A0A194PVU9   D9HQ40   A0A212FBT4   + More
D9HQ78   A0A220K8K3   G9D4L9   G9D4L8   G9D4L7   G9D4L3   G9D4M1   G9D4M0   G9D4L0   G9D4K8   G9D4L4   G9D4L5   G9D4L1   G9D4L2   A0A0N1IHQ9   H9JX11   A0A0L7L730   H9JV20   D9HQ20   A0A3S2L8X9   D9HQ62   A0A2H1W6E8   A0A0N1I2N0   A0A0N1PJ57   Q16TL8   Q16ID8   G9D476   G9D477   G9D470   G9D468   A0A182GET6   G9D473   G9D471   G9D469   G9D465   B0WIS4   A0A182GET7   O02570   G9D475   G9D474   G9D467   B0WDC9   A0A182G8J0   A0A182V8R1   A0A084VY04   A0A182ICF6   A0A084VY02   A0A084VY03   A0A084VY00   A0A182PCQ7   Q0IF85   A0A182L0V6   P29786-2   A0A182XL71   P35041   A0A1Q3FP18   P29786   B0WBW1   A0A1A9WKF8   B0WF77   A0A088A9M1   Q5QBG0   A0A182GUL7   A0A182F5Y2   K7J8G2   A0A182U4C7   F4MI40   A0A2C9GTY9   A0A1Y9J0J4   A0A1Y9J180   A0A0C9R5M5   A0A1Y9GKU7   A0A182VG56   P35035   A0A182TKI7   Q16KW4   A0A182V8D5   Q16TM0   A0A1Y9GLX5   A0A1Y9GKV0   A0A2K7P6D6   A0A1I8PQ52   P35036   A0A1B0DPM0   T1DEY9   P29787   Q5QBF4   P35037   A0A240PL34   A0A1S4GXU9   A0A182U9U3   P35048   A0A182T760   Q9XY52  

EC Number

3.4.21.4

Pubmed

28756777    26354079    20375075    21967427    22118469    28630352    + More
19121390    26227816    17510324    20100490    26483478    24438588    20966253    9087545    7498434    12364791    20075255    21569254    8335004    15796745    8269093   

EMBL

ODYU01007221    SOQ49809.1    KZ150532    PZC70593.1    NWSH01000148    PCG79058.1    + More
KQ459597    KPI95255.1    HM023795    JF777269    ADJ58528.1    AEU11614.1    AGBW02009280    OWR51183.1    HM023833    JF777262    ADJ58566.1    AEU11607.1    MF319702    ASJ26416.1    JF777272    AEU11617.1    JF777271    AEU11616.1    JF777270    AEU11615.1    JF777266    AEU11611.1    JF777274    AEU11619.1    JF777273    AEU11618.1    JF777263    AEU11608.1    JF777261    AEU11606.1    JF777267    AEU11612.1    JF777268    AEU11613.1    JF777264    AEU11609.1    JF777265    AEU11610.1    KQ460466    KPJ14599.1    BABH01041876    BABH01041877    BABH01041878    JTDY01002604    KOB71116.1    BABH01026404    BABH01026405    HM023775    JF777125    ADJ58508.1    AEU11470.1    RSAL01000085    RVE48362.1    HM023817    JF777119    ADJ58550.1    AEU11464.1    ODYU01006610    SOQ48603.1    KQ459572    KPI99586.1    KQ460448    KPJ14673.1    CH477645    EAT37859.1    GQ398049    CH478086    ACV07666.1    EAT34028.1    JF777129    AEU11474.1    JF777130    AEU11475.1    JF777123    AEU11468.1    JF777121    AEU11466.1    JXUM01058527    KQ562007    KXJ76926.1    JF777126    AEU11471.1    JF777124    AEU11469.1    JF777122    AEU11467.1    JF777118    AEU11463.1    DS231951    EDS28651.1    JXUM01058532    KXJ76927.1    U65412    AAB37261.1    JF777128    AEU11473.1    JF777127    AEU11472.1    JF777120    AEU11465.1    DS231896    EDS44442.1    JXUM01047815    KQ561534    KXJ78237.1    ATLV01018235    KE525226    KFB42848.1    APCN01000798    KFB42846.1    KFB42847.1    ATLV01018234    KFB42844.1    CH477389    EAT42001.1    AF487426    AF508783    X64362    CH477469    Z22930    AAAB01008964    GFDL01005706    JAV29339.1    DS231882    EDS42891.1    DS231915    EDS26053.1    EDS26054.1    AY752851    AAV84264.1    JXUM01089555    KQ563779    KXJ73325.1    EZ933288    ADJ57669.1    GBYB01002121    JAG71888.1    Z18889    CH477936    EAT34942.1    EAT37857.1    Z18890    AJVK01018397    GAMD01003326    JAA98264.1    X64363    AY752857    AAV84270.1    L08428    AF053910    AAD21830.1   

Proteomes

UP000218220    UP000053268    UP000007151    UP000053240    UP000005204    UP000037510    + More
UP000283053    UP000008820    UP000069940    UP000249989    UP000002320    UP000075903    UP000030765    UP000075840    UP000075885    UP000075882    UP000076407    UP000007062    UP000091820    UP000005203    UP000069272    UP000002358    UP000075902    UP000095300    UP000092462    UP000075901   

PRIDE

H9JX11    H9JV20    P29786    P35041    A0A088A9M1    P35035    + More
P35036    P29787   

Pfam

PF00089   Trypsin

Interpro

IPR001314   Peptidase_S1A        + More
IPR009003   Peptidase_S1_PA       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       
IPR033116   TRYPSIN_SER       
IPR012224   Pept_S1A_FX       

SUPFAM

SSF50494   SSF50494       

CDD

cd00190  Tryp_SPc

ProteinModelPortal

A0A2H1W9P5   A0A2W1BG09   A0A2A4K562   A0A194PVU9   D9HQ40   A0A212FBT4   + More
D9HQ78   A0A220K8K3   G9D4L9   G9D4L8   G9D4L7   G9D4L3   G9D4M1   G9D4M0   G9D4L0   G9D4K8   G9D4L4   G9D4L5   G9D4L1   G9D4L2   A0A0N1IHQ9   H9JX11   A0A0L7L730   H9JV20   D9HQ20   A0A3S2L8X9   D9HQ62   A0A2H1W6E8   A0A0N1I2N0   A0A0N1PJ57   Q16TL8   Q16ID8   G9D476   G9D477   G9D470   G9D468   A0A182GET6   G9D473   G9D471   G9D469   G9D465   B0WIS4   A0A182GET7   O02570   G9D475   G9D474   G9D467   B0WDC9   A0A182G8J0   A0A182V8R1   A0A084VY04   A0A182ICF6   A0A084VY02   A0A084VY03   A0A084VY00   A0A182PCQ7   Q0IF85   A0A182L0V6   P29786-2   A0A182XL71   P35041   A0A1Q3FP18   P29786   B0WBW1   A0A1A9WKF8   B0WF77   A0A088A9M1   Q5QBG0   A0A182GUL7   A0A182F5Y2   K7J8G2   A0A182U4C7   F4MI40   A0A2C9GTY9   A0A1Y9J0J4   A0A1Y9J180   A0A0C9R5M5   A0A1Y9GKU7   A0A182VG56   P35035   A0A182TKI7   Q16KW4   A0A182V8D5   Q16TM0   A0A1Y9GLX5   A0A1Y9GKV0   A0A2K7P6D6   A0A1I8PQ52   P35036   A0A1B0DPM0   T1DEY9   P29787   Q5QBF4   P35037   A0A240PL34   A0A1S4GXU9   A0A182U9U3   P35048   A0A182T760   Q9XY52  

PDB

5JYI     E-value=3.65348e-30,     Score=325

KEGG

101737614    no KO assigned | (RefSeq) trypsin-like

GO

GO:0004252   GO:0005509   GO:0016021   GO:0007596   GO:0005615   GO:0007586   GO:0008236   GO:0005576   GO:0006508   GO:0006221   GO:0016500   GO:0004930   GO:0006915   GO:0016651   GO:0046835   GO:0006281   GO:0006259  

Subcellular location

  
Secreted  

Length:

244

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.92502

Exp number, first 60 AAs:

1.88418

Total prob of N-in:

0.09622

outside

1  -  244

 

 

Pi

19.341227

Theta

20.501919

Tajima's D

-1.33411

CLR

0.002393

CSRT

0.0835958202089895

Interpretation

Uncertain