Gene

KWMTBOMO16554  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004550

Annotation

PREDICTED:_epidermal_growth_factor_receptor_kinase_substrate_8-like_isoform_X3_[Bombyx_mori]

Location

Bomo_Scaf013(+):52546-113730      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.603 Nuclear   Reliability : 1.959

CDS

ATGGCGATGCGTGGAGCTGGGGTGGCTGGGAGCGGTACCTCTCGGTCCCGGGGGGAAGCTCAGCGAACCCTGGACGAGTTTGATGAGCTAGCAGGCATACGAGGGGGTGAGGGAGGGGAGCGGTCAGTCTACGTGCTGGAACACCTGGCCACCTTCACAGTGACGAGAGAGACGGGGATTGTCTACCCCGCGGATGGCATGAGGAGGCTGCTGCAGCTGGAGAAAACCAATGGAATTTGGAGCCAAAAGATGCAATTGTCTTTGGAAGGACAGTGGGTTCTGGTTATGGATTACGAAACTGCTTCAGTGATGGAGCGGTTTCCGGCTTCGTGGGTTCATTCACCCACCGCATTCACGTCTCCAGAACCAGCTGAGCTCTACAACAACGTGCTCGCCTTCGTAGTGGGAGCTCCTGCGTCACCGGCAGCCGGCTCCCACCAGGAGGGAAGGAGAGAGCTACATATATTCCAGTGCCATGACGTCAGCGCGCAGACACTCGTGGAAGAGCTTAATGCTCTAAAGGGTGTCGGTCGAGACGGTTCCGCTGACGGAGGCCGCGACTTCATTATCGAGCGGGAGCGGGAGCGCGAGCGAGAAACAGAAAGCGACAGACCTCAGAGACAACAAATGTCCGCGCAATTGGGCCGCGACAGAGAAAGAGAAAGGGATAGAGACAGAGACCGTAGCGGCTCTGGGGGCGAAAGAGACGACGCTTCATCCACAGGCTCCGAGCGTCTATACGAACAAGACATCGCCATATTGAACCGTTGCTTCGACGACATAGAGAAGTTCATAGCAAGATTACAGCATGCGGCTGCAGCTTCAAGGGAATTGGAGAGGAGGAGAAGGTCCCGAGGAGGCAAGCGAGCGGCGGCTGGTGAAGGAATGCTCGCAATGAGAACCCGTCCTCCGCCAGAGCGTGATTTTGTCGATGTTTTGCAGAAATTTAAGCTGTCCTTCAATCTGTTGGCACGTTTGAGAGCTCATATCCATGACCCGAATGCTCCAGAGTTGGTTCATTTCTTGTTCACACCGCTGGCGCTGATTGTGGACGCAGCACAGGACGTCGCCGACGGCCGTCTCCCAGCTAGGGTTGTGCAACCTCTCCTCACGAGGGAGGCCTTGAACCTTCTGGCGAATTGCGTGACAAGCAAAGAAACTGAACTGTGGCACTCATTAGGAGACGCTTGGCTAATACCCAGGGAGCAATGGAAAACACAGATACCACCATATCAACCGGTTTTCATGGACGGATGGACTCCAGATTACCAAGTCGATGACCAACCTTTACGCAGGTCATCGCCCAGACGCAGCGAGCTGGGCAGGGGTACAATGGAACGGGGCGTGGAAAGGAGCGAGGGCGGGCAGGTGGCGGGTTTCACGTTCGAACGAGAGGAACCCGAGATATACAACGAGCAATACGCTCCGTTCGCCAGAAATAACTTGAGACCACCAATCGGCCGCGAAGATTCGGGCTCCGCTGCCTCATCGCCCGACAGAGAGCCCCCGTATCGCCCCGCAGACAGAGATGAAGCAGATTTGGGTGAAGCGTGGGCCCGGGGCGTTGCGGCCCGGGGAGGCCGCGTTGTGCGCGTCACCTACCCTCGCACTGCAAATAACGATAAAGAATTAACTGTCGTTAGGGGAGAGTATTTAGAGGTTCTAGATGATTCGAGAAAGTGGTGGAAGGCACGTAACAGACGCGGCGTGTCAGCGCACGTGCCACACACCATCGTGGCTCCCGCGTTTTCGCCGCCTTCGTCACCACACCTCTACCCTAATCCGATATACACACATTACCAGGATGGCGGGGGGAGAGCTTCGGGCGGCAGCAGTCCCACTGCGGCACCGGAGAAACCAGCGCCAAAGATTGAGGCGGCTGCTCCACCGCCCCCGCCGCCGCCTCCTCCACCCCCGGAGCCGCCGTCACCGCCACCCATCAAATCTGATACTTTGAAATCCACCAAATCGATAATGAGTACTGGCGGCAGTCTCCACGATGAACTGAAGCTAGTACTGCCCCAGATACAGCAAAGAAGAAACAAACTCGACATCAAGAAGACTCCAGATATATTCATTGATCAGAAATCGAATCCGGACGAGGTTGTGGAATGGCTCGAAGCAAAGGGTTTCAGCAATGCCGCCAACGCCAGCTGA

Protein

MAMRGAGVAGSGTSRSRGEAQRTLDEFDELAGIRGGEGGERSVYVLEHLATFTVTRETGIVYPADGMRRLLQLEKTNGIWSQKMQLSLEGQWVLVMDYETASVMERFPASWVHSPTAFTSPEPAELYNNVLAFVVGAPASPAAGSHQEGRRELHIFQCHDVSAQTLVEELNALKGVGRDGSADGGRDFIIERERERERETESDRPQRQQMSAQLGRDRERERDRDRDRSGSGGERDDASSTGSERLYEQDIAILNRCFDDIEKFIARLQHAAAASRELERRRRSRGGKRAAAGEGMLAMRTRPPPERDFVDVLQKFKLSFNLLARLRAHIHDPNAPELVHFLFTPLALIVDAAQDVADGRLPARVVQPLLTREALNLLANCVTSKETELWHSLGDAWLIPREQWKTQIPPYQPVFMDGWTPDYQVDDQPLRRSSPRRSELGRGTMERGVERSEGGQVAGFTFEREEPEIYNEQYAPFARNNLRPPIGREDSGSAASSPDREPPYRPADRDEADLGEAWARGVAARGGRVVRVTYPRTANNDKELTVVRGEYLEVLDDSRKWWKARNRRGVSAHVPHTIVAPAFSPPSSPHLYPNPIYTHYQDGGGRASGGSSPTAAPEKPAPKIEAAAPPPPPPPPPPPEPPSPPPIKSDTLKSTKSIMSTGGSLHDELKLVLPQIQQRRNKLDIKKTPDIFIDQKSNPDEVVEWLEAKGFSNAANAS

Uniprot

H9J4W0   A0A2A4JKR8   A0A212F5W3   V5GT81   A0A1W4XHK4   A0A1W4X8B5   + More
A0A1Y1MM04   A0A1Y1MM17   A0A067QSQ1   A0A154NXD6   A0A0P4VXY8   A0A0P4W5F0   A0A0N7ZB69   A0A0P4VXZ2   B7PEH9   A0A1W0X850   A0A1W0X822   V4AIY7  

Pubmed

19121390    22118469    28004739    24845553    23254933   

EMBL

BABH01025763    BABH01025764    BABH01025765    BABH01025766    BABH01025767    NWSH01001113    + More
PCG72551.1    AGBW02010136    OWR49099.1    GALX01003609    JAB64857.1    GEZM01027495    JAV86712.1    GEZM01027496    JAV86711.1    KK853326    KDR08458.1    KQ434778    KZC04319.1    GDRN01088665    JAI60817.1    GDRN01088664    GDRN01088663    JAI60818.1    GDRN01088666    JAI60816.1    GDRN01088661    JAI60820.1    ABJB010000716    ABJB010161222    ABJB010179999    ABJB010187217    ABJB010235136    ABJB010580279    ABJB010676480    ABJB010952188    ABJB010966625    DS695319    EEC05001.1    MTYJ01000010    OQV23697.1    OQV23696.1    KB201362    ESO97002.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000192223    UP000027135    UP000076502    + More
UP000001555    UP000030746   

PRIDE

H9J4W0   

Pfam

PF08416   PTB        + More
PF18016   SAM_3
PF00018   SH3_1

Interpro

IPR033928   EPS8_PTB        + More
IPR011993   PH-like_dom_sf       
IPR036028   SH3-like_dom_sf       
IPR039801   EPS8-like       
IPR001452   SH3_domain       
IPR035462   Eps8_SH3       
IPR013625   PTB       
IPR041418   SAM_3       
IPR013761   SAM/pointed_sf       
IPR006020   PTB/PI_dom       

SUPFAM

SSF50044   SSF50044        + More
SSF47769   SSF47769       

Gene 3D

2.30.29.30     1.10.150.50    

CDD

cd11764  SH3_Eps8
cd01210  PTB_EPS8

ProteinModelPortal

H9J4W0   A0A2A4JKR8   A0A212F5W3   V5GT81   A0A1W4XHK4   A0A1W4X8B5   + More
A0A1Y1MM04   A0A1Y1MM17   A0A067QSQ1   A0A154NXD6   A0A0P4VXY8   A0A0P4W5F0   A0A0N7ZB69   A0A0P4VXZ2   B7PEH9   A0A1W0X850   A0A1W0X822   V4AIY7  

PDB

1WXB     E-value=2.43111e-07,     Score=134

KEGG

101735591    K17277 epidermal growth factor receptor kinase substrate 8 | (RefSeq) epidermal growth factor recept

GO

GO:0016301   GO:0003779   GO:0007266   GO:0005886   GO:0035023   GO:0005515   GO:0006508   GO:0006468   GO:0016787   GO:0005622   GO:0006915   GO:0016651   GO:0046835   GO:0006281   GO:0006259  

PANTHER

PTHR12287  

Length:

718

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00632999999999999

Exp number, first 60 AAs:

0.00125

Total prob of N-in:

0.00043

outside

1  -  718

 

 

Pi

2.729979

Theta

2.800565

Tajima's D

-1.600909

CLR

0.000058

CSRT

0.0363481825908705

Interpretation

Uncertain