SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO16532  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA005641
Annotation
putative_mitogen-activated_protein_kinase_(MAPKK)_[Heliconius_melpomene]
Full name
Diacylglycerol kinase      
Location in the cell
Cytoplasmic   Reliability : 2.25
 

Sequence

CDS
ATGTCGAGAAGAAAACTGCCGCCCCCGGGCTTTAACTTCAAGACTCAAACGGAACAAGTTGTGACTCCACCAGGGAATTTAGATAAACAAACAACAATTACAGTTGATGATCGAACTTTCACTGTACATGCTGATGATTTGGTAAAGATTTGTGATCTTGGCCGAGGAGCATATGGTATTGTTGAGAAGATGCGCCACCTACCTAGCAACACCATTATGGCTGTTAAGAGAATCACAGCCACATTCAACAATCAATCTTTGGAACAAAAACGTTTGTTAATGGATCTTGATGTATCAATGAGAGCAAGTGCGTGTCCGTATACAGTACATTTCTACGGAGCAATGTTCAGGGAAGGGGATGTTTGGATTTGTATGGAAGTAATGGATATGAGTTTAGACAAATTTTACACAAAAGTCTACAAAAATGATCGTACCATACCTGAGAATATTCTTGGAAAGATAGCATTTTCGGTTGTTAGTGCTTTACATTATTTATACTCCAAACTCAGAGTCATACATAGAGATGTGAAACCATCAAATATATTGATCAACAGAAAGGGTGAAGTGAAGATGTGTGACTTTGGCATTTCTGGTCATCTGGTAGATTCTGTTGCAAAAACAATTGATGCTGGCTGTAAACCTTATATGGCACCAGAACGAATTGATCCAACTGGAAATCCTGGGCAATATGACATTCGAAGTGACGTGTGGTCTCTGGGAATATCCATGATTGAACTAGCAACAGGAACTTTCCCATACAACACATGGGGCACACCTTTCGAGCAACTAAAACAAGTTGTTAAAGATGATCCACCAAGGCTTCCAGTGGGAAAATTTTCAAACGAGTTTGAGGATTTAATAGTGCAATGCTTACAGAAAGACTATAGACTCAGACCAAATTACGATGCATTGTTAGTGCATCCATTCTGCCAGGAACACAGTCAAAAGGAAACAGATGTTGCATCTTTTGTTCAGGAAATATTAGATATAGCAGACAATGCTTAG
Protein
MSRRKLPPPGFNFKTQTEQVVTPPGNLDKQTTITVDDRTFTVHADDLVKICDLGRGAYGIVEKMRHLPSNTIMAVKRITATFNNQSLEQKRLLMDLDVSMRASACPYTVHFYGAMFREGDVWICMEVMDMSLDKFYTKVYKNDRTIPENILGKIAFSVVSALHYLYSKLRVIHRDVKPSNILINRKGEVKMCDFGISGHLVDSVAKTIDAGCKPYMAPERIDPTGNPGQYDIRSDVWSLGISMIELATGTFPYNTWGTPFEQLKQVVKDDPPRLPVGKFSNEFEDLIVQCLQKDYRLRPNYDALLVHPFCQEHSQKETDVASFVQEILDIADNA

Summary

Catalytic Activity
a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)
Similarity
Belongs to the protein kinase superfamily.
Belongs to the eukaryotic diacylglycerol kinase family.
EC Number
2.7.1.107
EMBL
BABH01020201    NWSH01001832    PCG69964.1    KC469893    AGC92692.1    FP102340    + More
CBH09282.1    ODYU01004701    SOQ44860.1    AGBW02013517    OWR43290.1    KQ459232    KPJ02628.1    GAIX01013942    JAA78618.1    KQ461155    KPJ08305.1    JTDY01000391    KOB77400.1    GEZM01099000    JAV53582.1    PYGN01000896    PSN39599.1    GECZ01008848    JAS60921.1    GECU01037056    GECU01036185    GECU01035622    GECU01034966    GECU01026631    GECU01023613    GECU01023593    GECU01021463    GECU01018946    GECU01017131    GECU01006000    GECU01005905    GECU01004573    GECU01003580    GECU01003023    GECU01002428    JAS70650.1    JAS71521.1    JAS72084.1    JAS72740.1    JAS81075.1    JAS84093.1    JAS84113.1    JAS86243.1    JAS88760.1    JAS90575.1    JAT01707.1    JAT01802.1    JAT03134.1    JAT04127.1    JAT04684.1    JAT05279.1    EF491249    ABR28347.1    KK107119    QOIP01000009    EZA58783.1    RLU18329.1    KK853134    KDR10863.1    GEBQ01021620    GEBQ01001690    JAT18357.1    JAT38287.1    KQ435711    KOX79423.1    GL446405    EFN87841.1    ADTU01002755    ADTU01002756    GL444277    EFN61068.1    KQ982431    KYQ56442.1    KQ980284    KYN16962.1    KQ976693    KYM77658.1    LBMM01002940    KMQ94158.1    GFDF01006558    JAV07526.1    KQ434789    KZC05350.1    GBYB01001722    JAG71489.1    GFDF01006559    JAV07525.1    LJIG01022489    KRT80305.1    KQ414989    KOC58975.1    KZ288451    PBC25568.1    NEVH01020858    PNF21021.1    AAZX01007551    AAZO01004340    DS235392    EEB15530.1    GALX01005912    JAB62554.1    KA646749    AFP61378.1    NNAY01001391    OXU24141.1    JXUM01007305    JXUM01007306    JXUM01007307    GAPW01002484    KQ560237    JAC11114.1    KXJ83678.1    GDAI01000688    JAI16915.1    KQ971361    EFA08029.1    GANO01003151    JAB56720.1    ABLF02040695    CH477222    EAT47270.1    AY358075    AAQ68075.1    GFDL01012090    JAV22955.1    GBGD01002100    JAC86789.1    GDKW01001556    JAI55039.1    GAHY01001331    JAA76179.1    CCAG010006445    EZ422251    ADD18527.1    KQ981285    KYN43211.1    DS231855    EDS38205.1    GFTR01005177    JAW11249.1    GDHF01021048    JAI31266.1    GECL01001404    JAP04720.1    GAKP01004758    JAC54194.1    UFQS01000212    UFQT01000212    SSX01406.1    SSX21786.1    GFXV01000415    MBW12220.1    KQ759840    OAD62646.1    GBXI01010246    GBXI01004816    JAD04046.1    JAD09476.1    JRES01001303    KNC23773.1    CH916371    EDV91749.1    GAMC01009365    GAMC01009363    JAB97190.1    CH902622    EDV34597.1    CH933812    EDW05817.1    CH479194    EDW26979.1    CM000162    EDX01526.1    CH940653    EDW62595.1    CH379063    EAL32736.2    OUUW01000021    SPP89409.1    CP012528    ALC48757.1    CVRI01000061    CRL04061.1    CH954180    EDV47244.1    CH964239    EDW82202.1    CH983901    EDX16580.1    CH480836    EDW48970.1    AF035549    AF035550    AF041136    AE014298    AY052103    AAC39033.1    AAC39034.1    AAF22365.1    AAF48223.1    AAK93527.1    AJ238572    CAB45101.1    KK854406    PTY15551.1    JH431533    GL732587    EFX73950.1    APGK01036393    KB740939    ENN77747.1    KB632013    ERL88044.1    GDIP01101263    JAM02452.1    GDIP01047375    JAM56340.1    GDIQ01173279    JAK78446.1    GDIP01235889    JAI87512.1    GDIP01149657    JAJ73745.1    GDIP01062764    JAM40951.1    GDIQ01268410    JAJ83314.1    GDIQ01083364    JAN11373.1   
Pfam
PF00069   Pkinase        + More
PF00609   DAGK_acc
PF00781   DAGK_cat
Interpro
IPR008271   Ser/Thr_kinase_AS        + More
IPR011009   Kinase-like_dom_sf       
IPR017441   Protein_kinase_ATP_BS       
IPR000719   Prot_kinase_dom       
IPR001206   Diacylglycerol_kinase_cat_dom       
IPR000756   Diacylglycerol_kin_accessory       
IPR037607   DGK       
IPR002219   PE/DAG-bd       
IPR017438   ATP-NAD_kinase_N       
IPR016064   NAD/diacylglycerol_kinase_sf       
IPR011990   TPR-like_helical_dom_sf       
IPR013026   TPR-contain_dom       
SUPFAM
SSF56112   SSF56112        + More
SSF111331   SSF111331       
SSF48452   SSF48452       
Gene 3D
PDB
3VN9     E-value=1.87899e-119,     Score=1097

Ontologies

Topology

Length:
334
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.2783
Exp number, first 60 AAs:
0
Total prob of N-in:
0.01569
outside
1  -  334
 
 

Population Genetic Test Statistics

Pi
7.326974
Theta
24.928626
Tajima's D
-2.176247
CLR
0
CSRT
0.00604969751512424
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
26822097 VTIAECHVIIAPWAAAIR 100.00 0.004
25044914 IDPSSEETKK 100.00 0.004
27102218 QTTITVDDR 100.00 0.004
28467696 IDPTFAHVDSVK 100.00 0.004
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