SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO16456  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA013812
Annotation
integument_esterase_1_precursor_[Bombyx_mori]
Full name
Carboxylic ester hydrolase      
Location in the cell
Cytoplasmic   Reliability : 1.416 Mitochondrial   Reliability : 1.222
 

Sequence

CDS
ATGTTGTTGAAATTAATATTTATTTGTGCCATTGTGTATTATGCTGATGCTCATAAGAACAATAAGAAACAAACAGAAAAAAGACCAGCAGAGCCCGATGGCCCAGTGACCCGTTCACAATCTGGCTCATTCTTGGGCTCATGGATGGAGACACGTCGCGGAAAGCAGTTCCAGGCCTATAGGGGCATAAGATACGCTGAACCACCGGTCGGGAAACTACGATTCCAGCCCCCAAAACTAATTCGGCAATACAAAGAACGCGTTGACGCGAGCAAAGAGGGCCCGGCCTGCCCTCTGCCCGTCCCTCCCACTTACTACGTCGACGAAGACTGCCTGAGAATCAACGTGTATACTCCTAGTAACAATGTCTCGAAGCCTCTCCCTGTGATATTTTACATTCACGCCGGAGCGTTCTACTCCATGACGGGCAGGAGCGACCTGGCCGGACCTCACTACTTGCTGGACAGAGATCTGGTGCTCGTCACCATCAACTACAGGCTCGGCTCTTTAGGTTTTATAAGCACAGGCGACTCCCTGGCTCCTGGTAACAATGGGATGAAGGACCAAGTAGCCGCCCTGCGCTGGGTGCAGAGGAACATCAGAGCTTTTGGAGGAGATCCTGACTTAGTCACCATTGCCGGGTGCAGTGCTGGCTCTATCAGTGTGATGCTTCACATGATATCGCCTATGTCTAAAGGACTCTTCCACCGCGGTATATCGATGAGCGGGTCTCCGTTCGCGAGGGAGCCGCTACCGACAGAGCAGAAGAATCTGGCCATTCGTCAAGCCGAGATCCTCGACTGTCCTACCAACTCCAGCAAGGCCATCATGGACTGTCTCATGGCTAAAGATTGGAGGGAGATCGGAGATTCATTGCCAAAGTTCTTCGAATCCGGGCCGGGCGGGCCGGTGGGTATGTGGTGGCCGGTAGTGGAGGTGGATGCGGGCCAGGAGCGATTCTTGTCGGAGCAGCCCCTGGGCGTCCTCAGGTCGGGCCGCGCGCACACCGTGCCGCACATCATCAGCCAAACCAAGGACGAGTTCTTCTGGAAAGCTCCTCCGGTACTCCAGAACGAGACGCTGCTAGATGAATTAAACAACGACTGGGAGAACATAGCGCCCATATACTTCAGCTTGCCGCAAGAGAACCGGACGGCCGCGGTGAGGGAGCTGAGGGCGCAGTACCTCGGGGACGGCCCGCTGCGGAACGACGAGCGTTCCACCCGCGCCCTCGGCAGACTCTACGGAGACTCTATCATAGGGTTCGGCGTTCACAGAATGGTGAAGCTCATGAGTCGTCACTCGGAGTATCCAGTGTACTATTACGTGTTCAGCTACATCGGCAATAACAGCTATTACGTGGATCCTGGCACCGGGAAACCAGCTGGAGCTGCTCACCACGACGACACCATCTACGTGCTCACTCAGTCGTACCAGTTCCCCACCATACAGACGGACAGCCCCGACTCCCACGTCGTTGACGAGATGACTGCCATCTGGTACAACTTCGCTAGACACGGCGATCCAAACAACTGCGGCGACACCCCGGAGATCGGGGTCCGGTGGCCGGAGTACGACCCCGCCAAGCAGCAGTACCTGGACGTGGGAGACAGACTCACTGTCCGCAAAAACTACGCTGAAGACAGATTCCAGCTCTGGGATGAGCTATATCCTATACAATACTAA
Protein
MLLKLIFICAIVYYADAHKNNKKQTEKRPAEPDGPVTRSQSGSFLGSWMETRRGKQFQAYRGIRYAEPPVGKLRFQPPKLIRQYKERVDASKEGPACPLPVPPTYYVDEDCLRINVYTPSNNVSKPLPVIFYIHAGAFYSMTGRSDLAGPHYLLDRDLVLVTINYRLGSLGFISTGDSLAPGNNGMKDQVAALRWVQRNIRAFGGDPDLVTIAGCSAGSISVMLHMISPMSKGLFHRGISMSGSPFAREPLPTEQKNLAIRQAEILDCPTNSSKAIMDCLMAKDWREIGDSLPKFFESGPGGPVGMWWPVVEVDAGQERFLSEQPLGVLRSGRAHTVPHIISQTKDEFFWKAPPVLQNETLLDELNNDWENIAPIYFSLPQENRTAAVRELRAQYLGDGPLRNDERSTRALGRLYGDSIIGFGVHRMVKLMSRHSEYPVYYYVFSYIGNNSYYVDPGTGKPAGAAHHDDTIYVLTQSYQFPTIQTDSPDSHVVDEMTAIWYNFARHGDPNNCGDTPEIGVRWPEYDPAKQQYLDVGDRLTVRKNYAEDRFQLWDELYPIQY

Summary

Similarity
Belongs to the type-B carboxylesterase/lipase family.
Feature
chain  Carboxylic ester hydrolase
EC Number
3.1.1.-
EMBL
BABH01029396    BABH01029397    EU328352    ABY57298.1    FJ556876    ACL83459.1    + More
KF960779    AII21981.1    NWSH01000325    PCG77440.1    HQ116561    ADR64702.1    MF687554    ATJ44480.1    MF687623    ATJ44549.1    KZ150111    PZC73330.1    FJ652448    ACV60232.1    KU375428    APD13870.1    AY091504    AAM14416.1    ODYU01000992    SOQ36586.1    AB072256    BAC22502.1    ODYU01002118    SOQ39209.1    ODYU01009159    SOQ53392.1    KX015847    ARM65376.1    JTDY01001491    KOB73744.1    KQ459054    KPJ03876.1    RSAL01000471    RVE41610.1    AK402149    BAM18771.1    AGBW02013941    OWR42542.1    KP938890    AKS40371.1    KQ459670    KPJ20505.1    KQ459866    KPJ19691.1    KP001147    AJN91192.1    KP001150    AJN91195.1    PZC73332.1    GCVX01000024    JAI18206.1    AGBW02010035    OWR49316.1    KY021845    AQY62734.1    KU375434    APD13876.1    EU647213    ACD03181.1    KPJ20489.1    FJ652459    ACV60243.1    KF960787    AII21989.1    KP938881    AKS40362.1    PZC73331.1    KJ023203    AIY69031.1    ODYU01008145    SOQ51504.1    KU215368    AMB19662.1    ODYU01002498    SOQ40051.1    LC017763    BAR64777.1    ODYU01002465    SOQ39989.1    KP001148    AJN91193.1    BABH01040271    BABH01040272    KPJ03892.1    KY021844    AQY62733.1    FJ997324    ADF43489.1    KX015858    ARM65387.1    GEYN01000035    JAV02094.1    GCVX01000027    JAI18203.1    RSAL01000351    RVE42264.1    PCG77460.1    GEZM01075891    JAV63896.1    KP859361    AKZ17671.1    KP859351    AKZ17661.1    GBYB01009074    JAG78841.1    KX609461    ARN17868.1    KM220539    AIY68330.1    GEZM01054549    JAV73566.1    KQ971357    EFA08586.1    GL888609    EGI59059.1    ADTU01000291    ADTU01000292    BT127705    AEE62667.1    GL440715    EFN65473.1    KQ414590    KOC70368.1    AAZX01001198    GAPW01000794    JAC12804.1    NNAY01000280    OXU29530.1    KY021839    AQY62728.1    GGFJ01003866    MBW53007.1    GGFM01000522    MBW21273.1    GGFM01000505    MBW21256.1    GAPW01000793    JAC12805.1    GGFK01002488    MBW35809.1    GGFK01002483    MBW35804.1    GGFK01002477    MBW35798.1    KQ971343    EFA04389.1    GGFK01002476    MBW35797.1    ADMH02000998    ETN64479.1    KK107250    EZA54385.1    CH916369    EDV93633.1    CH940650    EDW66949.1    EZ424149    ADD20425.1    CH477532    EAT39446.1    KQ434839    KZC07956.1    NEVH01017460    PNF24246.1    KJ702188    AID61342.1    CP012526    ALC45678.1    KQ760478    OAD60210.1    EFN65474.1    GEZM01077562    GEZM01077561    JAV63272.1   
Pfam
PF00135   COesterase        + More
PF00405   Transferrin
Interpro
IPR029058   AB_hydrolase        + More
IPR019826   Carboxylesterase_B_AS       
IPR002018   CarbesteraseB       
IPR019819   Carboxylesterase_B_CS       
IPR018195   Transferrin_Fe_BS       
IPR001156   Transferrin-like_dom       
SUPFAM
SSF53474   SSF53474       
Gene 3D
PDB
5FV4     E-value=3.44114e-50,     Score=502

Ontologies

Topology

SignalP
Position:   1 - 17,         Likelihood:  0.902456
 
 
Length:
561
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.13491
Exp number, first 60 AAs:
0.00413
Total prob of N-in:
0.00446
outside
1  -  561
 
 

Population Genetic Test Statistics

Pi
235.477921
Theta
181.411755
Tajima's D
1.132582
CLR
0
CSRT
0.693365331733413
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
27102218 HGDPNNCGDTPEIGVRWPEYDPAK 96.97 5e-18
27102218 SDIAGPHYIIDRDIVIVTINYR 100.00 6e-12
25860555 HDKCPAFICGPQK 100.00 1e-07
27102218 AQYIGDGPIR 100.00 1e-07
29197581 AHTVPHIISQTK 100.00 1e-07
25860555 CIDGYVR 100.00 4e-06
24093152 HFQTDFR 100.00 4e-06
27102218 KNYAEDRFQIWDEIYPIQY 100.00 4e-06
28467696 HGAVTDIKDQGK 100.00 4e-06
29197581 GISMSGSPFAREPIPTEQK 100.00 4e-06
27102218 SDIAGPHYIIDR 100.00 0.001
29197581 QQYIDVGDR 100.00 0.001
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