Gene

KWMTBOMO16456  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013812

Annotation

integument_esterase_1_precursor_[Bombyx_mori]

Location

Bomo_Chr28(-):10402333-10413717      View in EpiBrowser

Full name

Carboxylic ester hydrolase      

Location in the cell

Cytoplasmic   Reliability : 1.416 Mitochondrial   Reliability : 1.222

CDS

ATGTTGTTGAAATTAATATTTATTTGTGCCATTGTGTATTATGCTGATGCTCATAAGAACAATAAGAAACAAACAGAAAAAAGACCAGCAGAGCCCGATGGCCCAGTGACCCGTTCACAATCTGGCTCATTCTTGGGCTCATGGATGGAGACACGTCGCGGAAAGCAGTTCCAGGCCTATAGGGGCATAAGATACGCTGAACCACCGGTCGGGAAACTACGATTCCAGCCCCCAAAACTAATTCGGCAATACAAAGAACGCGTTGACGCGAGCAAAGAGGGCCCGGCCTGCCCTCTGCCCGTCCCTCCCACTTACTACGTCGACGAAGACTGCCTGAGAATCAACGTGTATACTCCTAGTAACAATGTCTCGAAGCCTCTCCCTGTGATATTTTACATTCACGCCGGAGCGTTCTACTCCATGACGGGCAGGAGCGACCTGGCCGGACCTCACTACTTGCTGGACAGAGATCTGGTGCTCGTCACCATCAACTACAGGCTCGGCTCTTTAGGTTTTATAAGCACAGGCGACTCCCTGGCTCCTGGTAACAATGGGATGAAGGACCAAGTAGCCGCCCTGCGCTGGGTGCAGAGGAACATCAGAGCTTTTGGAGGAGATCCTGACTTAGTCACCATTGCCGGGTGCAGTGCTGGCTCTATCAGTGTGATGCTTCACATGATATCGCCTATGTCTAAAGGACTCTTCCACCGCGGTATATCGATGAGCGGGTCTCCGTTCGCGAGGGAGCCGCTACCGACAGAGCAGAAGAATCTGGCCATTCGTCAAGCCGAGATCCTCGACTGTCCTACCAACTCCAGCAAGGCCATCATGGACTGTCTCATGGCTAAAGATTGGAGGGAGATCGGAGATTCATTGCCAAAGTTCTTCGAATCCGGGCCGGGCGGGCCGGTGGGTATGTGGTGGCCGGTAGTGGAGGTGGATGCGGGCCAGGAGCGATTCTTGTCGGAGCAGCCCCTGGGCGTCCTCAGGTCGGGCCGCGCGCACACCGTGCCGCACATCATCAGCCAAACCAAGGACGAGTTCTTCTGGAAAGCTCCTCCGGTACTCCAGAACGAGACGCTGCTAGATGAATTAAACAACGACTGGGAGAACATAGCGCCCATATACTTCAGCTTGCCGCAAGAGAACCGGACGGCCGCGGTGAGGGAGCTGAGGGCGCAGTACCTCGGGGACGGCCCGCTGCGGAACGACGAGCGTTCCACCCGCGCCCTCGGCAGACTCTACGGAGACTCTATCATAGGGTTCGGCGTTCACAGAATGGTGAAGCTCATGAGTCGTCACTCGGAGTATCCAGTGTACTATTACGTGTTCAGCTACATCGGCAATAACAGCTATTACGTGGATCCTGGCACCGGGAAACCAGCTGGAGCTGCTCACCACGACGACACCATCTACGTGCTCACTCAGTCGTACCAGTTCCCCACCATACAGACGGACAGCCCCGACTCCCACGTCGTTGACGAGATGACTGCCATCTGGTACAACTTCGCTAGACACGGCGATCCAAACAACTGCGGCGACACCCCGGAGATCGGGGTCCGGTGGCCGGAGTACGACCCCGCCAAGCAGCAGTACCTGGACGTGGGAGACAGACTCACTGTCCGCAAAAACTACGCTGAAGACAGATTCCAGCTCTGGGATGAGCTATATCCTATACAATACTAA

Protein

MLLKLIFICAIVYYADAHKNNKKQTEKRPAEPDGPVTRSQSGSFLGSWMETRRGKQFQAYRGIRYAEPPVGKLRFQPPKLIRQYKERVDASKEGPACPLPVPPTYYVDEDCLRINVYTPSNNVSKPLPVIFYIHAGAFYSMTGRSDLAGPHYLLDRDLVLVTINYRLGSLGFISTGDSLAPGNNGMKDQVAALRWVQRNIRAFGGDPDLVTIAGCSAGSISVMLHMISPMSKGLFHRGISMSGSPFAREPLPTEQKNLAIRQAEILDCPTNSSKAIMDCLMAKDWREIGDSLPKFFESGPGGPVGMWWPVVEVDAGQERFLSEQPLGVLRSGRAHTVPHIISQTKDEFFWKAPPVLQNETLLDELNNDWENIAPIYFSLPQENRTAAVRELRAQYLGDGPLRNDERSTRALGRLYGDSIIGFGVHRMVKLMSRHSEYPVYYYVFSYIGNNSYYVDPGTGKPAGAAHHDDTIYVLTQSYQFPTIQTDSPDSHVVDEMTAIWYNFARHGDPNNCGDTPEIGVRWPEYDPAKQQYLDVGDRLTVRKNYAEDRFQLWDELYPIQY

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Feature

chain  Carboxylic ester hydrolase

Uniprot

H9JW98   B0FGV8   B8YPE6   A0A076FX71   A0A2A4K191   E5KG18   + More
A0A291P0U7   A0A291P108   A0A2W1BKS7   D3GDL6   A0A1J0M1W5   Q86MC6   A0A2H1V723   Q76LV8   A0A2H1VEG4   A0A2H1WKG0   A0A2S0D926   A0A0L7LEE9   A0A194QK91   A0A3S2P4M1   I4DLI1   A0A212EM26   A0A0K0XRX2   A0A0N1IIX7   A0A0N0PEB7   A0A0C5CGX5   A0A0C5C585   A0A2W1BDQ9   A0A0K8TVB4   A0A212F6F1   A0A1U9X1V2   A0A1J0M181   B2ZDZ0   A0A0N1IIX1   D3GDM7   A0A076FT16   A0A0K0XRW3   A0A2W1BGD8   A0A0B4RXV7   A0A2H1WGB8   A0A0Y0BNW5   A0A2H1VH21   A0A0F7QJW7   A0A2H1VGL5   A0A0C5BXG4   H9JJ43   A0A194QEI5   A0A1U9X1V4   D5G3G0   A0A2S0D932   A0A1L8D6X6   A0A0K8TV90   A0A3S2TCS4   A0A2A4K1B6   K7INH0   A0A1Y1KWW8   A0A0K1YW45   A0A0K1YW36   A0A0C9QZ47   A0A1W6L1A2   A0A0A7EQ91   A0A1Y1LPN2   D6WVK5   F4X378   A0A158NKA1   J3JWT7   K7INH2   E2AM67   A0A0L7RHV8   K7IV21   A0A023EWG4   A0A232FG81   A0A1U9X1T6   A0A2M4BIY1   A0A2M3YYC3   A0A2M3YYC8   A0A023ETW1   A0A2M4A4W3   A0A2M4A4R8   A0A2M4A574   D6WNV1   A0A2M4A4R9   W5JNZ8   A0A026WE54   B4JG66   A0A182FLE8   B4LYF3   D3TRU7   Q16XU6   A0A1I8PXX8   A0A154P7P8   A0A2J7Q6N2   A0A068F7U5   A0A1S4FKP8   A0A0M4ED55   K7INH1   A0A310STR5   E2AM68   A0A1Y1KPD4  

EC Number

3.1.1.-

Pubmed

19121390    24817326    24753123    28986331    28756777    26227816    + More
26354079    22651552    22118469    26198868    26017144    26778204    25803580    20005949    20075255    28004739    18362917    19820115    21719571    21347285    22516182    20798317    24945155    28648823    20920257    23761445    24508170    17994087    20353571    17510324    25880816   

EMBL

BABH01029396    BABH01029397    EU328352    ABY57298.1    FJ556876    ACL83459.1    + More
KF960779    AII21981.1    NWSH01000325    PCG77440.1    HQ116561    ADR64702.1    MF687554    ATJ44480.1    MF687623    ATJ44549.1    KZ150111    PZC73330.1    FJ652448    ACV60232.1    KU375428    APD13870.1    AY091504    AAM14416.1    ODYU01000992    SOQ36586.1    AB072256    BAC22502.1    ODYU01002118    SOQ39209.1    ODYU01009159    SOQ53392.1    KX015847    ARM65376.1    JTDY01001491    KOB73744.1    KQ459054    KPJ03876.1    RSAL01000471    RVE41610.1    AK402149    BAM18771.1    AGBW02013941    OWR42542.1    KP938890    AKS40371.1    KQ459670    KPJ20505.1    KQ459866    KPJ19691.1    KP001147    AJN91192.1    KP001150    AJN91195.1    PZC73332.1    GCVX01000024    JAI18206.1    AGBW02010035    OWR49316.1    KY021845    AQY62734.1    KU375434    APD13876.1    EU647213    ACD03181.1    KPJ20489.1    FJ652459    ACV60243.1    KF960787    AII21989.1    KP938881    AKS40362.1    PZC73331.1    KJ023203    AIY69031.1    ODYU01008145    SOQ51504.1    KU215368    AMB19662.1    ODYU01002498    SOQ40051.1    LC017763    BAR64777.1    ODYU01002465    SOQ39989.1    KP001148    AJN91193.1    BABH01040271    BABH01040272    KPJ03892.1    KY021844    AQY62733.1    FJ997324    ADF43489.1    KX015858    ARM65387.1    GEYN01000035    JAV02094.1    GCVX01000027    JAI18203.1    RSAL01000351    RVE42264.1    PCG77460.1    GEZM01075891    JAV63896.1    KP859361    AKZ17671.1    KP859351    AKZ17661.1    GBYB01009074    JAG78841.1    KX609461    ARN17868.1    KM220539    AIY68330.1    GEZM01054549    JAV73566.1    KQ971357    EFA08586.1    GL888609    EGI59059.1    ADTU01000291    ADTU01000292    BT127705    AEE62667.1    GL440715    EFN65473.1    KQ414590    KOC70368.1    AAZX01001198    GAPW01000794    JAC12804.1    NNAY01000280    OXU29530.1    KY021839    AQY62728.1    GGFJ01003866    MBW53007.1    GGFM01000522    MBW21273.1    GGFM01000505    MBW21256.1    GAPW01000793    JAC12805.1    GGFK01002488    MBW35809.1    GGFK01002483    MBW35804.1    GGFK01002477    MBW35798.1    KQ971343    EFA04389.1    GGFK01002476    MBW35797.1    ADMH02000998    ETN64479.1    KK107250    EZA54385.1    CH916369    EDV93633.1    CH940650    EDW66949.1    EZ424149    ADD20425.1    CH477532    EAT39446.1    KQ434839    KZC07956.1    NEVH01017460    PNF24246.1    KJ702188    AID61342.1    CP012526    ALC45678.1    KQ760478    OAD60210.1    EFN65474.1    GEZM01077562    GEZM01077561    JAV63272.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053268    UP000283053    UP000007151    + More
UP000053240    UP000002358    UP000007266    UP000007755    UP000005205    UP000000311    UP000053825    UP000215335    UP000000673    UP000053097    UP000001070    UP000069272    UP000008792    UP000008820    UP000095300    UP000076502    UP000235965    UP000092553   

PRIDE

H9JW98    B0FGV8    B2ZDZ0    H9JJ43   

Pfam

PF00135   COesterase        + More
PF00405   Transferrin

Interpro

IPR029058   AB_hydrolase        + More
IPR019826   Carboxylesterase_B_AS       
IPR002018   CarbesteraseB       
IPR019819   Carboxylesterase_B_CS       
IPR018195   Transferrin_Fe_BS       
IPR001156   Transferrin-like_dom       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

H9JW98   B0FGV8   B8YPE6   A0A076FX71   A0A2A4K191   E5KG18   + More
A0A291P0U7   A0A291P108   A0A2W1BKS7   D3GDL6   A0A1J0M1W5   Q86MC6   A0A2H1V723   Q76LV8   A0A2H1VEG4   A0A2H1WKG0   A0A2S0D926   A0A0L7LEE9   A0A194QK91   A0A3S2P4M1   I4DLI1   A0A212EM26   A0A0K0XRX2   A0A0N1IIX7   A0A0N0PEB7   A0A0C5CGX5   A0A0C5C585   A0A2W1BDQ9   A0A0K8TVB4   A0A212F6F1   A0A1U9X1V2   A0A1J0M181   B2ZDZ0   A0A0N1IIX1   D3GDM7   A0A076FT16   A0A0K0XRW3   A0A2W1BGD8   A0A0B4RXV7   A0A2H1WGB8   A0A0Y0BNW5   A0A2H1VH21   A0A0F7QJW7   A0A2H1VGL5   A0A0C5BXG4   H9JJ43   A0A194QEI5   A0A1U9X1V4   D5G3G0   A0A2S0D932   A0A1L8D6X6   A0A0K8TV90   A0A3S2TCS4   A0A2A4K1B6   K7INH0   A0A1Y1KWW8   A0A0K1YW45   A0A0K1YW36   A0A0C9QZ47   A0A1W6L1A2   A0A0A7EQ91   A0A1Y1LPN2   D6WVK5   F4X378   A0A158NKA1   J3JWT7   K7INH2   E2AM67   A0A0L7RHV8   K7IV21   A0A023EWG4   A0A232FG81   A0A1U9X1T6   A0A2M4BIY1   A0A2M3YYC3   A0A2M3YYC8   A0A023ETW1   A0A2M4A4W3   A0A2M4A4R8   A0A2M4A574   D6WNV1   A0A2M4A4R9   W5JNZ8   A0A026WE54   B4JG66   A0A182FLE8   B4LYF3   D3TRU7   Q16XU6   A0A1I8PXX8   A0A154P7P8   A0A2J7Q6N2   A0A068F7U5   A0A1S4FKP8   A0A0M4ED55   K7INH1   A0A310STR5   E2AM68   A0A1Y1KPD4  

PDB

5FV4     E-value=3.44114e-50,     Score=502

KEGG

100141431    no KO assigned | (RefSeq) ie1, BmCarE-7, Bmie1, Care-7; integument esterase 1

GO

GO:0016787   GO:0005615   GO:0052689   GO:0005576  

SignalP

Position:   1 - 17,         Likelihood:  0.902456

 

 

Length:

561

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.13491

Exp number, first 60 AAs:

0.00413

Total prob of N-in:

0.00446

outside

1  -  561

 

 

Pi

235.477921

Theta

181.411755

Tajima's D

1.132582

CLR

0

CSRT

0.693365331733413

Interpretation

Uncertain