Gene
KWMTBOMO16442
Pre Gene Modal
BGIBMGA013822
Annotation
PREDICTED:_hyaluronidase-like_[Bombyx_mori]
Full name
Hyaluronidase
Alternative Name
Hyaluronoglucosaminidase
Location in the cell
Nuclear Reliability : 1.242
Sequence
CDS
ATGCAGTGCAGAAGCAAGAAGATCCCGTTCGAAGATCTGTTCGAAAAGTTCGGGATACTTCAGAACGAAAACGACAGTTTCCTGGGAAAGGCCGTCTCCATCCTGTACGATCCCGGGCTTTTCCCGGCCCTGCTCACCAACGAAACCAGCGGTCAGATAATATTCCGCAACGGAGGAGTTCCACAGGAGGGCGACTTGGCGAAGCATTTGGAGGTTTTCAGGAGGAATTTGGTGCAATGCGTACCTGACGAAGATTTTAGTGGAGTCGGCATTATCGATTTCGAATCCTGGCGGCCGATCTTCAGGCAAAACTTTGGCGCTTTAGTTCCATACAAGGACGTGTCGTATGAGATAGAAAAGAAACTTCACTGGTGGTGGCCCAAGCAATGGGTGCAGACTGAGGCAATACAACGCTTTGAAGAATCAGCGCGGACCTTCATGCAGAGGACGCTCTTAGTGGCGAAAGAGATGAGGCCTAACGCGCAGTGGGGATACTACGGGTTCCCGTACTGTTTCAACATGGCCAGCAACAACATGAAGGAGTCTTGTGCCGAAAAGGTTCCTGAGGAAAACGATAGGCTACATTGGCTGTGGTCAGAGAGCACCGCTCTGTACCCCTCGATATACAGCTCGCGGGATCTGACGTCATCCCAACTGTCCCGGATGATCCGAGGACGTATTAAGGAGGCCCAGAGACTCAATAGGAATGACGCGCCGGTGCTGCCTTACTTCTGGTTCCGCTACAGAGACGGCGGGTACATGACTGAAGAAGACCTCAATTCGGCCCTGCAAGCGATATACGCCTCGAACGCCTCAGGGTTCATAGTGTGGGGCAGCTCCAACGACGTCAACACAGTTAAAAAATGTCACAATTTACGTGAATATCTCGAGGGCACGTTGGGGCCGGCCATAGCCAAATATACCGGGTCACAAATCAGAAACGTCCCAACAGAAGACGTCGACACTACAACCACAGCCTCCAGCACAGTCTTAGCAAATTACGACCCGGACTACCACTGGGATCCTCCTGACAACTACGAACAAAACATTCAAAAATACGTCAACGATGAAATGAAAAACAAAACTGGATACGACAAAACGAACGCCAGCTTCCCATTACATAGCTATAATGATAACGCACTTATAAATATGATACTTAATAACTTTATCACTAATGACAGTGATGTGAACAATGACAGTTCGATAAGTAACGTGACGAGCGCAGGTCACGCGAGCACGCAGACCGCTGACACTGACATGACAACTGTCCGGTTGGATACAACGCAAACTAATGAGTATTATGCTTCGTTCAATGATAATACAACAGAAATACTAGATAACACAGAGAGCACAACAGTAGAAGGAACAAATTTACAAGATGTAACAACAAATGATGTATTTAAATTCTTCAATGAAGACACATTCAATGAATTCTCAAGCAATAACACGCTAGATACTGATACAGAAACTAGTGACGTCACAGAAGATAATTATCCCAAAGAATTAGATGTTTCTAGAAAGGATACGGACAGCGATCCAACCACGGCGCCACCTAACAGTCAGGTGTCGGGTACTGCTTCAGTCATCGGTCTGGGACGCCTTCTGTATATGTCTGTGTTTTTATTTGTGTAA
Protein
MQCRSKKIPFEDLFEKFGILQNENDSFLGKAVSILYDPGLFPALLTNETSGQIIFRNGGVPQEGDLAKHLEVFRRNLVQCVPDEDFSGVGIIDFESWRPIFRQNFGALVPYKDVSYEIEKKLHWWWPKQWVQTEAIQRFEESARTFMQRTLLVAKEMRPNAQWGYYGFPYCFNMASNNMKESCAEKVPEENDRLHWLWSESTALYPSIYSSRDLTSSQLSRMIRGRIKEAQRLNRNDAPVLPYFWFRYRDGGYMTEEDLNSALQAIYASNASGFIVWGSSNDVNTVKKCHNLREYLEGTLGPAIAKYTGSQIRNVPTEDVDTTTTASSTVLANYDPDYHWDPPDNYEQNIQKYVNDEMKNKTGYDKTNASFPLHSYNDNALINMILNNFITNDSDVNNDSSISNVTSAGHASTQTADTDMTTVRLDTTQTNEYYASFNDNTTEILDNTESTTVEGTNLQDVTTNDVFKFFNEDTFNEFSSNNTLDTDTETSDVTEDNYPKELDVSRKDTDSDPTTAPPNSQVSGTASVIGLGRLLYMSVFLFV
Summary
Catalytic Activity
Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
Similarity
Belongs to the glycosyl hydrolase 56 family.
Feature
chain Hyaluronidase
Uniprot
EC Number
3.2.1.35
Proteomes
PRIDE
Pfam
PF01630 Glyco_hydro_56
Interpro
SUPFAM
SSF51445
SSF51445
Gene 3D
ProteinModelPortal
PDB
2J88
E-value=1.90251e-82,
Score=780
Ontologies
PATHWAY
GO
PANTHER
Topology
Length:
543
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.26891
Exp number, first 60 AAs:
0.02305
Total prob of N-in:
0.00428
outside
1 - 543
Population Genetic Test Statistics
Pi
285.395322
Theta
187.329195
Tajima's D
1.380201
CLR
0.169258
CSRT
0.75851207439628
Interpretation
Uncertain
