Gene

KWMTBOMO16435

Pre Gene Modal

BGIBMGA013872

Annotation

PREDICTED:_insulin_gene_enhancer_protein_ISL-1_[Bombyx_mori]

Location

Bomo_Chr28(+):9902034-9928004      View in EpiBrowser

Transcription factor

Homeobox

Location in the cell

Nuclear   Reliability : 4.255

CDS

ATGGCACAAAAAGAAAATCGCTCTCATCCAGCCTCCGAAAAGCTCCGGCTCTCGTTGTGCGTCGGCTGCGGAGGTCAGATCCACGACCAGTACATCCTCCGGGTGGCCCCTGACTTGGAGTGGCACGCGGCCTGCCTAAAGTGTCAGGAATGCCGGCAGTTCCTCGACGAATCCTGCACGTGCTTCGTTAGAGACGGAAAGACTTATTGCAAAAGAGATTATACTAGATTATTCGGCACGAAATGCGACAAATGCGGCGCGTCCTTCAGTAAAAACGACTTCGTGATGCGTGCCAAGACGAAGATATACCACATAGATTGTTTTAGATGCTGCGCTTGTGCCCGACAACTTATACCTGGTGACGAATTCGCGTTGCGAGAAGGCGGAGCGCTCTATTGTAGAGAAGATCACGATGTTTTAGAAAAGAGCGCGAACACGAGCGGCGGGAGTAGTAATAATGCCGAGAGCAACAATAATACGACGCTAAGTAACAATAACTCGCATCATCCCCATGAGCTGGGGTCTATGTCAGATTCTGGGAGCGAATCCGGCTCTCACAAGAGTGGTCGGGCGCGGACCACAGCGGCGGCCGACGGTAAGCCGACCCGAGTCCGGACCGTGCTGAATGAAAAGCAACTGCACACGTTACGGACTTGCTACGCCGCCAACCCACGTCCGGACGCACTGATGAAGGAGCAGCTCGTGGAGATGACCGGCCTCAGTCCAAGGGTCATCAGGGTCTGGTTCCAGAACAAACGGTGCAAAGACAAAAAAAAGACGTTGCAGCTCAAAATGCAGATGCAACAAGAGAAGGAGGGTCGGCGGCTGGGCTACATGTCTGTGGGCGTGCCGCTGGTGGCGGGCGCGCCCGTGCGGCACGAGGCCGGCGGCGCGCTGGAGGTGAGCTCGTACCAGCCGCCCTGGAAGGCGCTGTCCGACTTCGCGCTGCACGCAGACCTGGACCGCGCGCCGCACCACTCAGCCGCCTTCCAGCACCTTGTCAACCAGATGCACGGGTACGACGTGCCCCCCCTGCCGGCGCCGCGCGGTCCCCCCGGGGGCGAGGACCATTACGTCACGTACCTGGAGAGCGACGACAGCCTCCCCCCCTCCCCCTAG

Protein

MAQKENRSHPASEKLRLSLCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYTRLFGTKCDKCGASFSKNDFVMRAKTKIYHIDCFRCCACARQLIPGDEFALREGGALYCREDHDVLEKSANTSGGSSNNAESNNNTTLSNNNSHHPHELGSMSDSGSESGSHKSGRARTTAAADGKPTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKTLQLKMQMQQEKEGRRLGYMSVGVPLVAGAPVRHEAGGALEVSSYQPPWKALSDFALHADLDRAPHHSAAFQHLVNQMHGYDVPPLPAPRGPPGGEDHYVTYLESDDSLPPSP

Uniprot

A0A2A4J305   A0A0N1I9N4   A0A2H1VPM0   A0A336MVA6   A0A1B0CKX2   Q17L14   + More
A0A1Y1KQ03   A0A1S4EYY1   Q7PMI4   A0A182I0Q3   A0A1Y1KUH9   A0A182N8P9   A0A182P8C4   A0A182YHB7   A0A182FMU2   A0A182R6V2   A0A1S4H3A9   A0A182XB58   A0A182VSZ1   A0A0K8WJ87   A0A182V1E7   A0A0L0BZR6   A0A3B0JAI4   A0A0Q9WAN4   A0A0Q9X437   A0A1I8N979   A0A3B0J9N5   A0A0K8UJ70   A0A034WH90   B3MLS6   A0A0A9XDI3   B4LU95   B4KHC4   B3NL83   A0A1W4VLE4   B4PAC9   Q29MY5   B4G8J1   Q9Y0Z9   B4I5M2   B4Q8Z7   Q9VJ37   P92031   A0A182KBE1   A0A3B0JEA6   A0A1A9VJC3   A0A1B0AV50   A0A1A9ZLZ9   A0A1I8NZD7   B4MTS3   A0A067RAL5   A0A1A9Y5N6   A0A1B0FIP3   K7J9D1   A0A212F1S0   A0A1B6DVK5   A0A1B6E3W2   A0A3Q0E4L3   G3R2B6   A0A2I3LTF5   A0A341B048   A0A2Y9LQ30   W5PEU1   D2HCK6   A0A2K5PN66   L5KKJ9   A0A1S3FDG9   G5C265   A0A061ILJ5   I3MKS5   A0A1U7QNL2   H0V6A5   A0A091D1I7   A2RSV5   A0A2K6DK81   A0A2K6K779   A0A384C8I4   G1TSL8   A0A2K5VBK8   G1RIK5   F1SMF7   A0A2K5XS53   A0A0D9RVX7   G3TJI2   F6YLT7   A0A2Y9DSS7   A0A2U3V9B1   A0A3Q7NM45   A0A340YEE1   A0A2R9B1B8   A0A2K5C137   A0A096N282   A0A2Y9EWU9   A0A2K6P0S2   A0A2Y9HRT1   A0A2U3XJV0   M3WF59   A0A2K5MRF3   A0A2J8V5Y7  

Pubmed

26354079    17510324    28004739    12364791    25244985    26108605    + More
17994087    25315136    25348373    25401762    17550304    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    9115734    24845553    20075255    22118469    22398555    20809919    20010809    23258410    21993625    23929341    21993624    12040188    15489334    24813606    30723633    19892987    22722832    25362486    17975172   

EMBL

NWSH01003557    PCG66116.1    KQ460047    KPJ18002.1    ODYU01003693    SOQ42773.1    + More
UFQS01001296    UFQT01001128    UFQT01001296    SSX10156.1    SSX29058.1    SSX29878.1    AJWK01016686    AJWK01016687    AJWK01016688    CH477219    EAT47413.1    GEZM01077199    JAV63374.1    AAAB01008980    EAA13793.5    APCN01005230    GEZM01077198    JAV63375.1    GDHF01001185    JAI51129.1    JRES01001109    KNC25503.1    OUUW01000004    SPP78985.1    CH940649    KRF81414.1    CH933807    KRG02565.1    SPP78984.1    GDHF01025929    JAI26385.1    GAKP01004006    JAC54946.1    CH902620    EDV30797.1    GBHO01024813    GBHO01024812    JAG18791.1    JAG18792.1    EDW64082.1    EDW11188.1    CH954179    EDV54733.1    CM000158    EDW90337.1    CH379060    EAL33558.2    CH479180    EDW28671.1    AF145674    AE014134    AAD38649.1    AAN11018.1    CH480822    EDW55678.1    CM000361    CM002910    EDX05429.1    KMY90893.1    AAF53720.1    AHN54582.1    U89385    AAB49892.1    SPP78983.1    JXJN01003962    CH963852    EDW75512.2    KK852632    KDR19799.1    CCAG010006998    AGBW02010820    OWR47689.1    GEDC01007619    JAS29679.1    GEDC01004697    JAS32601.1    CABD030105030    CABD030105031    AHZZ02029097    AMGL01034858    GL192688    EFB17970.1    KB030662    ELK12174.1    JH172958    EHB15626.1    KE667846    ERE84718.1    AGTP01014306    AAKN02031585    KN123491    KFO24842.1    BC132263    BC132609    CH466568    AAI32264.1    EDL18368.1    AAGW02030699    AAGW02030700    AQIA01058748    ADFV01095232    AEMK02000102    DQIR01095073    HDA50549.1    AQIB01086355    AJFE02096184    AJFE02096185    AC235013    NDHI03003432    PNJ52955.1   

Proteomes

UP000218220    UP000053240    UP000092461    UP000008820    UP000007062    UP000075840    + More
UP000075884    UP000075885    UP000076408    UP000069272    UP000075900    UP000076407    UP000075920    UP000075903    UP000037069    UP000268350    UP000008792    UP000009192    UP000095301    UP000007801    UP000008711    UP000192221    UP000002282    UP000001819    UP000008744    UP000000803    UP000001292    UP000000304    UP000075881    UP000078200    UP000092460    UP000092445    UP000095300    UP000007798    UP000027135    UP000092443    UP000092444    UP000002358    UP000007151    UP000189704    UP000001519    UP000028761    UP000252040    UP000248483    UP000002356    UP000233040    UP000010552    UP000081671    UP000006813    UP000030759    UP000005215    UP000189706    UP000005447    UP000028990    UP000233120    UP000233180    UP000261680    UP000291021    UP000001811    UP000233100    UP000001073    UP000008227    UP000233140    UP000029965    UP000007646    UP000002281    UP000248480    UP000245320    UP000286641    UP000265300    UP000240080    UP000233020    UP000248484    UP000233200    UP000248481    UP000245341    UP000011712    UP000233060   

PRIDE

Q9Y0Z9    Q9VJ37    P92031    F1SMF7   

Pfam

PF00046   Homeodomain        + More
PF00412   LIM

Interpro

IPR001356   Homeobox_dom        + More
IPR009057   Homeobox-like_sf       
IPR001781   Znf_LIM       
IPR017970   Homeobox_CS       

SUPFAM

SSF46689   SSF46689       

CDD

cd00086  homeodomain

ProteinModelPortal

A0A2A4J305   A0A0N1I9N4   A0A2H1VPM0   A0A336MVA6   A0A1B0CKX2   Q17L14   + More
A0A1Y1KQ03   A0A1S4EYY1   Q7PMI4   A0A182I0Q3   A0A1Y1KUH9   A0A182N8P9   A0A182P8C4   A0A182YHB7   A0A182FMU2   A0A182R6V2   A0A1S4H3A9   A0A182XB58   A0A182VSZ1   A0A0K8WJ87   A0A182V1E7   A0A0L0BZR6   A0A3B0JAI4   A0A0Q9WAN4   A0A0Q9X437   A0A1I8N979   A0A3B0J9N5   A0A0K8UJ70   A0A034WH90   B3MLS6   A0A0A9XDI3   B4LU95   B4KHC4   B3NL83   A0A1W4VLE4   B4PAC9   Q29MY5   B4G8J1   Q9Y0Z9   B4I5M2   B4Q8Z7   Q9VJ37   P92031   A0A182KBE1   A0A3B0JEA6   A0A1A9VJC3   A0A1B0AV50   A0A1A9ZLZ9   A0A1I8NZD7   B4MTS3   A0A067RAL5   A0A1A9Y5N6   A0A1B0FIP3   K7J9D1   A0A212F1S0   A0A1B6DVK5   A0A1B6E3W2   A0A3Q0E4L3   G3R2B6   A0A2I3LTF5   A0A341B048   A0A2Y9LQ30   W5PEU1   D2HCK6   A0A2K5PN66   L5KKJ9   A0A1S3FDG9   G5C265   A0A061ILJ5   I3MKS5   A0A1U7QNL2   H0V6A5   A0A091D1I7   A2RSV5   A0A2K6DK81   A0A2K6K779   A0A384C8I4   G1TSL8   A0A2K5VBK8   G1RIK5   F1SMF7   A0A2K5XS53   A0A0D9RVX7   G3TJI2   F6YLT7   A0A2Y9DSS7   A0A2U3V9B1   A0A3Q7NM45   A0A340YEE1   A0A2R9B1B8   A0A2K5C137   A0A096N282   A0A2Y9EWU9   A0A2K6P0S2   A0A2Y9HRT1   A0A2U3XJV0   M3WF59   A0A2K5MRF3   A0A2J8V5Y7  

PDB

4JCJ     E-value=1.34041e-58,     Score=573

KEGG

101741760    K09370 insulin gene enhancer protein ISL-1 | (RefSeq) insulin gene enhancer protein ISL-1

GO

GO:0005634   GO:0046872   GO:0006355   GO:0043565   GO:0000981   GO:0007409   GO:0045944   GO:0048665   GO:0035310   GO:0000980   GO:0001102   GO:0008045   GO:0043433   GO:0070983   GO:0008407   GO:0035050   GO:0007521   GO:0007390   GO:0046665   GO:0007391   GO:0048542   GO:0022416   GO:0000977   GO:0007411   GO:0007507   GO:0008258   GO:0010468   GO:0003677   GO:0003713   GO:0032730   GO:0090090   GO:0031290   GO:0003148   GO:0021520   GO:0000122   GO:0032725   GO:0032729   GO:0032760   GO:0042531   GO:0035066   GO:0060413   GO:0001158   GO:0001755   GO:0048880   GO:0021559   GO:0048936   GO:0045665   GO:0060037   GO:0043425   GO:0032735   GO:0045597   GO:0003266   GO:0060379   GO:0050728   GO:0060384   GO:0021524   GO:0003215   GO:0005654   GO:0008284   GO:0003139   GO:1990841   GO:0010575   GO:0032731   GO:0031016   GO:0003203   GO:0043388   GO:0060913   GO:0032755   GO:0055010   GO:0021983   GO:0071657   GO:0043524   GO:0045766   GO:0032024   GO:0031103   GO:0001228   GO:0000978   GO:0050680   GO:0090074   GO:0033147   GO:0010718   GO:0030331   GO:0071385   GO:0008270   GO:0005839   GO:0051603   GO:0046835   GO:0006281   GO:0006259  

Subcellular location

Nucleus  

Length:

372

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01866

Exp number, first 60 AAs:

0.00055

Total prob of N-in:

0.02992

outside

1  -  372

 

 

Pi

25.027611

Theta

185.689337

Tajima's D

1.020683

CLR

0.612237

CSRT

0.670616469176541

Interpretation

Uncertain