SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO16422  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA013860
Annotation
UDP-glycosyltransferase_UGT33D5_precursor_[Bombyx_mori]
Location
Bomo_Chr28(+):9251707-9262935      View in EpiBrowser
Location in the cell
PlasmaMembrane   Reliability : 2.227
 

Sequence

CDS
ATGATAGTGTATTTTGTGGCAATTTTACAAGAAATACAAGCGGCTCGGATCCTAGGCGTGTTCCCTATACCCTCAATCAGTCATCAAGTAGTCTTCCGTCGTCTGACCTTAGAGCTTCACAAAAGGGGTCATGAACTAGTGGTTGTGACCACTGACCCTGTGTTCAAAACAGGACAAGCACCTGCGAATTACACAGAAATAGATGTACATGACGTTTCTTATTCAGCCTGGAGAGACGGCTTCATGAAAACCTCTAAAGGAAACGCTAATGATCTTTACGAACAAATCGCCATTGCTTTAAACTTGGGCATAGATTTGCTTGAACTACAAATGAAAAACAAAGAAGTCCAAGCGTTGCTAAGGAAGAGAAAAGAGAAGAAGTTTGATTTGCTCCTTCTAGAAGCATGCATCAGATCAACGATGGTCTTGACGCATGTGTTTGATGCACCGGCAATCCTCATCAGTTCATTTGGAGGTGTAGAATTCATGTCGAAAATGATGGGTGTCCCAACCCATCCTATTTTATATCCACCACCGTTGCATCAAAGACTTTATAATTTAACGTTCTTGGAGAAAATCGGTGAGATATACACCCATTACTATATGGAGTATCTATATTGGCGATCTGAACCCCAGGAGAATCAAATGGCAAAAAGGCTTTTCGGCCCGAACACTCCAACTATCAGAGAAACCCAGAAGAACGTACAGATGGCACTCCTGAATGTACACGCGATTTGGGAGGAAAATCGTCCTGTCCCTCCGAATGTTATATACATTGGAGGTATTCATCAGAATCCAGAAAAAAACTTGCCCAAGGATTTGAAGGAATATTTAGACTCTTCAAAACATGGCGTTATATACATTAGTTTCGGCACCAACGTGGAACCATCGTTACTACCTCCAGAACGGATTCAACTCTTCATTAAAGTGTTCTCCGAACTGCCTTACGATGTGCTCTGGAAATGGGACAAAGATGAACTGCCCGGGAGCTCAAAGAACATCAGAATAGCAAAGTGGCTGCCTCAATCAGATTTACTTAGACACCCAAAGATCAAGGCGTTCATAACTCAAGGGGGTCTGCAATCGACCGAAGAAGCGATCACAGCTGGAGTGCCACTGATTGGAATGCCTATGTTGATGGACCAGTGGTACAATGTCGAGAAATACGTTCGACACAACATCGGTTTGAGACTCGATTTGGGTTCCGTTACAGAGGAATCTCTCAGAAATGCCATCAACACTATCACTGGTGACGAAAGCTACCGTCAGAATATAGCTCGTCTCCGTAGTCAGGTCTACGATCAGCCCCAGAGCTCAGTAGACCGCGCCGTGTGGTGGACTGAGCACGTGCTGCGCCACGGAGGAGCCACTCATCTCCGAGCCGCAGGAGCCTTGAAATCTTGGACTGAATATTTTGAACTAAATTTAATTGCAGTTTTACTAGTCACTTTCCTAATTGTTATTGCATTAATTGCAAGCAACGGTGTGTTCCAAAGAGTACTTGTGATGACAAATATGTTTTCTTTAAACAAGATAGTGCTTATTGTGACAATTATACACGGAACCCAAGCGGCTCGGATCCTAGGCGTGTTCCCTACACCCTCAATCAGTCATCAAGTAGTCTTCCGTCGTCTGACCTTAGAGCTTCACAAAAGGGGTCATGAACTAGTGGTTGTGACCACTGACCCGGTGTTCAAAACAGGACAAGCACCTGCGAATTACACAGAAATAGACGTACACGACGTTTCTTATTCAGCCTGGAGAGACGGCTTCATGAAAACCTCTAGGGGAAGCGCCAATGATATTTACGAACAAATTTCCAGAATGTTGAACTTAAGAATAGATTTGTTTGAATTGCAGATGAAAAATAAAGAAGTGCAGTCGCTGCTGAGTAAGAGAAAAGAGAGCAAGTTTGATTTGCTCCTTCTAGAAGCATGCATCAGACCAACGATGGTCTTGACGCATGTGTTTGATGCACCAGCAATCCTCATCAGTTCATTTGGGGGTGTAGAATTCGTCTTGAAAATGATTGGTGTCCCAACCCATCCTATATTATATCCACCTTCCTTGCACCAACGAATTTATAACTTAACATTTTCGGAGAAAATCCGAGAGGTTTACACTCATTACTATTTGGAATATCTATATTGGCGATCTGAACCCCAGGAGAATCAAATGGCAAAAAGGCTTTTCGGCCCGAACACTCCAACTATCAGAGAGACACAGAAGAACGTGCAGATGGCACTCCTGAATGTACACGCGATTTGGGAGGAAAATCGTCCTGTCCCTCCGAATGTTATATACATTGGAGGTATTCATCAGAATCCCGAAAAGGAATTGCCCAAGGATTTGAAGGAATATTTAGACTCTTCAAAACATGGCGTTATATACATTAGTTTCGGCACCAACGTGGAACCATCGCTACTACCTCCAGAACGGATTCAAATCCTCGTCAAAGTATTTTCCAAGCTGCCTTACGATGTGCTCTGGAAATGGGACAAAGATGAACTGCCCGGGAGCTCAAAGAACATCAGAATAGCAAAATGGCTGCCTCAATCAGATTTACTGAGACACCCAAAGATCAAGGCATTCATAACTCAAGGGGGTCTGCAATCGACGGAAGAAGCAATCACAGCTGGAGTGCCACTGATTGGAATGCCTATGTTGATGGACCAATGGTACAATGTCGAGAAATACGTTCGACACAACATCGGTTTGAGACTCGATTTGGGTTCCGTTACAGAGGAATCTCTCAGGAACGCCATCGACACTATCACTGGTGATGAAAGCTACCGTCAGAACATAGCTCGTCTCCGTAGTCAGGTCTACGATCAGCCCCAGAGCTCAGTTGACCGCGCCGTGTGGTGGACTGAGCACGTGCTGCGCCACGGAGGAGCCACTCATCTCCGAGCTGCAGGAGCCCTGAAATCTTGGACTGAATATTTTGAACTAAATTTAATTGCAGTATTATTAGTTACTTTCCTAATTATAATTACATTCATAGCAAAATTAATATCTTCGTTTGTGAGGTCATTGAAAATGTATTTCAATTATAATGATAAAGTAAAATTACATTGA
Protein
MIVYFVAILQEIQAARILGVFPIPSISHQVVFRRLTLELHKRGHELVVVTTDPVFKTGQAPANYTEIDVHDVSYSAWRDGFMKTSKGNANDLYEQIAIALNLGIDLLELQMKNKEVQALLRKRKEKKFDLLLLEACIRSTMVLTHVFDAPAILISSFGGVEFMSKMMGVPTHPILYPPPLHQRLYNLTFLEKIGEIYTHYYMEYLYWRSEPQENQMAKRLFGPNTPTIRETQKNVQMALLNVHAIWEENRPVPPNVIYIGGIHQNPEKNLPKDLKEYLDSSKHGVIYISFGTNVEPSLLPPERIQLFIKVFSELPYDVLWKWDKDELPGSSKNIRIAKWLPQSDLLRHPKIKAFITQGGLQSTEEAITAGVPLIGMPMLMDQWYNVEKYVRHNIGLRLDLGSVTEESLRNAINTITGDESYRQNIARLRSQVYDQPQSSVDRAVWWTEHVLRHGGATHLRAAGALKSWTEYFELNLIAVLLVTFLIVIALIASNGVFQRVLVMTNMFSLNKIVLIVTIIHGTQAARILGVFPTPSISHQVVFRRLTLELHKRGHELVVVTTDPVFKTGQAPANYTEIDVHDVSYSAWRDGFMKTSRGSANDIYEQISRMLNLRIDLFELQMKNKEVQSLLSKRKESKFDLLLLEACIRPTMVLTHVFDAPAILISSFGGVEFVLKMIGVPTHPILYPPSLHQRIYNLTFSEKIREVYTHYYLEYLYWRSEPQENQMAKRLFGPNTPTIRETQKNVQMALLNVHAIWEENRPVPPNVIYIGGIHQNPEKELPKDLKEYLDSSKHGVIYISFGTNVEPSLLPPERIQILVKVFSKLPYDVLWKWDKDELPGSSKNIRIAKWLPQSDLLRHPKIKAFITQGGLQSTEEAITAGVPLIGMPMLMDQWYNVEKYVRHNIGLRLDLGSVTEESLRNAIDTITGDESYRQNIARLRSQVYDQPQSSVDRAVWWTEHVLRHGGATHLRAAGALKSWTEYFELNLIAVLLVTFLIIITFIAKLISSFVRSLKMYFNYNDKVKLH

Summary

Similarity
Belongs to the UDP-glycosyltransferase family.
Belongs to the peptidase S1 family.
Uniprot
H9JWE6   A0A2H1VU94   A0A2H1VUS4   A0A0N1ICS6   A0A2H1WSA7   A0A2H1W0F9   + More
A0A0N1IQG9   H9JWC2   A0A0N1ICT4   H9JWC0   A0A0N0P9D3   A0A212F2V3   A0A0L7LGS1   A0A212F6X6   A0A0L7LF59   A0A2H1V761   A0A0L7L346   A0A1J1J4D9  
Pubmed
19121390    26354079    22118469    26227816   
EMBL
BABH01029273    BABH01029274    ODYU01004485    SOQ44409.1    ODYU01004546    SOQ44548.1    + More
KQ459547    KPJ00041.1    ODYU01010294    SOQ55304.1    ODYU01005543    SOQ46493.1    KQ459680    KPJ20473.1    BABH01029238    BABH01029239    BABH01029240    KPJ00055.1    BABH01029259    KPJ00049.1    AGBW02010679    OWR48052.1    JTDY01001195    KOB74579.1    AGBW02009962    OWR49474.1    JTDY01001352    KOB74102.1    ODYU01001030    SOQ36683.1    JTDY01003324    KOB69741.1    CVRI01000067    CRL06668.1   
Proteomes
UP000005204    UP000053268    UP000053240    UP000007151    UP000037510    UP000183832    + More
PRIDE
H9JWE6    H9JWC2    H9JWC0   
Pfam
PF00201   UDPGT        + More
PF00089   Trypsin
Interpro
IPR035595   UDP_glycos_trans_CS        + More
IPR002213   UDP_glucos_trans       
IPR033116   TRYPSIN_SER       
IPR001314   Peptidase_S1A       
IPR009003   Peptidase_S1_PA       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       
IPR006326   UDPGT_MGT       
SUPFAM
SSF50494   SSF50494       
CDD
cd00190  Tryp_SPc
ProteinModelPortal
H9JWE6   A0A2H1VU94   A0A2H1VUS4   A0A0N1ICS6   A0A2H1WSA7   A0A2H1W0F9   + More
A0A0N1IQG9   H9JWC2   A0A0N1ICT4   H9JWC0   A0A0N0P9D3   A0A212F2V3   A0A0L7LGS1   A0A212F6X6   A0A0L7LF59   A0A2H1V761   A0A0L7L346   A0A1J1J4D9  
PDB
2O6L     E-value=3.92996e-27,     Score=306

Ontologies

KEGG
100862845    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT33D5; UDP-glycosyltransferase UGT33D5
PATHWAY
00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
GO
GO:0016021   GO:0016758   GO:0004252   GO:0016999   GO:0008152   GO:0008270   GO:0043565   GO:0005839   GO:0051603   GO:0046835   GO:0006281   GO:0006259  

Topology

Length:
1025
Number of predicted TMHs:
3
Exp number of AAs in TMHs:
66.6076500000001
Exp number, first 60 AAs:
0.3199
Total prob of N-in:
0.03257
outside
1  -  470
TMhelix
471  -  493
inside
494  -  499
TMhelix
500  -  522
outside
523  -  986
TMhelix
987  -  1009
inside
1010  -  1025
 
 

Population Genetic Test Statistics

Pi
188.42675
Theta
175.766254
Tajima's D
1.111697
CLR
0.525218
CSRT
0.688965551722414
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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