Gene

KWMTBOMO16418

Pre Gene Modal

BGIBMGA013833

Annotation

UDP-glycosyltransferase_UGT33D3_[Bombyx_mori]

Location

Bomo_Chr28(-):9148417-9150936      View in EpiBrowser

Full name

UDP-glucuronosyltransferase      

Location in the cell

Cytoplasmic   Reliability : 1.879 Mitochondrial   Reliability : 1.482

CDS

ATGCCTTCAATTAGTCATCAAGTGGTCTTTCGTTCTTTGACACTGGAGCTGGCGAAAAGAGGCCACGAGCTTGTCGTTCTCACGACTGATCCTGTCTTTCATAAGGGAACCTCACCAGGAAACTACACAGAAATAGATGTCCACGACAACTCCTACCAAATATGGAGAAACAGTTTCCTTCAAACATCAAAAGGCAAACTTCAAGATCGCTTTGAAGAGGCCAGACTAGTAGTGGACGTAATACATCAGTTGTTTATCAAACAATTGTTAACGGATGAGTTTCAAGAAATATTGAGAAGCAAAAAGAAATTCGATTTGGTAATTCTAGAGGCCATGATGAAACCAGCTAGAGTGCTTTGTCACGTGTTCAATGCACCTGCTGTAATCATAAGTTCCTTGGGAGGTATCGGAGATATTTACGACATTGTTGGAGCCCCAACCCATCCGTTATTGTATCCAGTATGGATACGTCGAAGGCTGCATAATCTGTCTTTCTGGGAGAAATTGAGCGAATTATACAATCATTATACCTTCGAACGCTTGTGGAATGAACTGGAGGAGAAAGATAATGAGCTGGTCCAGAGTGCGTTTGGGATTAATATGCCAAAACTAAATGATATGGTGGATAATATCAGTTTGATTCTGTTGAACGTACATCCGATTTGGGAACACAATCGTCCGGTTCCACCGAATCTTATTTATATTGGAGGTATTCATCAGAAGCCACAAAAGGCATTGCCTTCGGATCTTAAAACGTATTTAGACTCGTCCAAACACGGGGTAATTTACATCAGTTTTGGTACGAACGTGATACCTTCGCTGTTGTCGCCAGAACGAATCCAAGTCCTGATCAAAGTGTTCTCCCAACTGCCCTACGATGTGCTGTGGAAGTGGGATAAAGATGAGCTGCCGGGAAAGTCGAAAAATATCAGGACTTCGAAGTGGCTGCCACAATCTGATCTGCTTAGGCACCCGAAGGTTAAGCTTTTTATAACCCAAGGTGGTCTGCAGTCTACGGAAGAAGCGATCACCGCTGGAGTGCCACTGATTGGAATGCCGATGTTAGGAGATCAGTGGTACAACGTGGAACTTTACGTATTCCATAAAATCGGAGTAAAACTTGACATGGACAAACTGTCTGAAGAGACACTCAGATATAGCATTCAAGAGGTCATTGGTGATGAAAGTTACCGTCAGAACATAGCTCGTCTTCGAACACAAGTGTATGATCAGCCTCAGAGCCCTTTGGAGCGCGCCGTGTGGTGGACGGAGTACGTGCTGCGTCACGGAGGAGCCAAGCATCTGCGAGCTGCCGGCGCCAATCTATCCTGGTCACAATATTTGGACTTAGAACTTACTTCAGCATTATTCATTACTTTTGATTTTACGTAG

Protein

MPSISHQVVFRSLTLELAKRGHELVVLTTDPVFHKGTSPGNYTEIDVHDNSYQIWRNSFLQTSKGKLQDRFEEARLVVDVIHQLFIKQLLTDEFQEILRSKKKFDLVILEAMMKPARVLCHVFNAPAVIISSLGGIGDIYDIVGAPTHPLLYPVWIRRRLHNLSFWEKLSELYNHYTFERLWNELEEKDNELVQSAFGINMPKLNDMVDNISLILLNVHPIWEHNRPVPPNLIYIGGIHQKPQKALPSDLKTYLDSSKHGVIYISFGTNVIPSLLSPERIQVLIKVFSQLPYDVLWKWDKDELPGKSKNIRTSKWLPQSDLLRHPKVKLFITQGGLQSTEEAITAGVPLIGMPMLGDQWYNVELYVFHKIGVKLDMDKLSEETLRYSIQEVIGDESYRQNIARLRTQVYDQPQSPLERAVWWTEYVLRHGGAKHLRAAGANLSWSQYLDLELTSALFITFDFT

Catalytic Activity

glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP

Similarity

Belongs to the UDP-glycosyltransferase family.
Belongs to the peptidase S1 family.

Feature

chain  UDP-glucuronosyltransferase

Uniprot

G9LPS4   H9JWB9   G9LPS8   G9LPS7   H9JWE6   G9LPS9   + More
B7TZA3   G9LPS3   H9JWB7   G9LPS6   G9LPS5   G9LPS2   F1DG68   Q1HPX7   M4M1W9   A0A2W1BL20   G9LPP3   A0A0L7LF59   A0A191T2J5   A0A2H1WTF5   A0A191T1L8   G9LPP5   A0A024AH14   A0A2H1W0F9   A0A2H4WB73   A0A191T1L3   A0A2A4IVU8   A0A1L8D6T8   A0A2W1B475   A0A2H1VUS4   A0A2H1VU94   A0A191T1L2   A0A2H1W7S2   A0A2I6RJL8   G9LPN7   G9LPP7   A0A2W1BA70   A0A2W1BHP8   A0A024AGL3   A0A2W1B485   A0A2W1BQP4   A0A0N1IB27   A0A191T2J2   G9LPN3   A0A2W1B8G2   G9LPN8   A0A2W1BEA5   A0A2W1B3V4   A0A2H1WSA7   A0A2W1BBH1   A0A2W1B675   A0A024AG00   A0A191T1K4   A0A2W1B7N5   A0A191T1K8   G9LPP0   G9LPN2   A0A2W1B8D3   G9LPP2   G9LPN6   A0A2W1BCY8   A0A191T2F8   A0A0N1I2R8   G9LPN9   A0A024AGF9   G9LPN4   G9LPP4   A0A2W1BE55   G9LPP1   A0A2W1B6A2   A0A2H1VUM4   A0A2W1B3X2   A0A2W1BEB8   A0A2W1BDA5   G9LPT1   A0A2A4JWQ0   A0A0N0PE43   A0A2W1B9W6   A0A191T1M4   G9LPN5   A0A140EA35   A0A2H4WB75   A0A2W1BHY3   A0A191T1N0   H9JWB6   A0A191T2G1   A0A191T2G3   A0A2H1V761   A0A0N0P9C8   A0A0N1ICS6   G9LPT0   A0A2W1BAD4   G9LPP6   A0A1L8D6R8   H9JWC2   A0A2A4JXE4   A0A0N1IQG9   D2JLK8   A0A0N1ICT4   A0A0N0P9D3  

EC Number

2.4.1.17

Pubmed

22155036    19121390    28756777    26227816    24698447    29027758    + More
26354079    26873292    19954531    21505429   

EMBL

JQ070231    AEW43147.1    BABH01029259    BABH01029260    JQ070235    AEW43151.1    + More
JQ070234    AEW43150.1    BABH01029273    BABH01029274    BABH01029271    JQ070236    AEW43152.1    FJ418685    ACJ48963.1    JQ070230    AEW43146.1    BABH01029269    BABH01029270    JQ070233    AEW43149.1    JQ070232    AEW43148.1    JQ070229    AEW43145.1    HQ833816    ADY17534.1    DQ443275    ABF51364.1    JQ747500    AGG36457.1    KZ150193    PZC72373.1    JQ070200    AEW43116.1    JTDY01001352    KOB74102.1    KU680289    ANI21995.1    ODYU01010933    SOQ56350.1    KU680281    ANI21987.1    JQ070202    AEW43118.1    KF777111    AHY99682.1    ODYU01005543    SOQ46493.1    KY202933    AUC64277.1    KU680288    ANI21994.1    NWSH01005967    PCG63789.1    GEYN01000079    JAV02050.1    KZ150360    PZC71189.1    ODYU01004546    SOQ44548.1    ODYU01004485    SOQ44409.1    KU680287    ANI21993.1    ODYU01006890    SOQ49139.1    KY304474    AUN86405.1    JQ070194    AEW43110.1    JQ070204    AEW43120.1    PZC71195.1    PZC71193.1    KF777112    AHY99683.1    PZC71199.1    KZ149974    PZC75964.1    KQ459547    KPJ00043.1    KU680284    ANI21990.1    JQ070190    AEW43106.1    PZC71201.1    JQ070195    AEW43111.1    PZC71190.1    PZC71192.1    ODYU01010294    SOQ55304.1    PZC71194.1    KZ150704    PZC70375.1    KF777109    AHY99680.1    KU680283    ANI21989.1    PZC70374.1    KU680282    ANI21988.1    JQ070197    AEW43113.1    JQ070189    AEW43105.1    PZC71191.1    JQ070199    AEW43115.1    JQ070193    AEW43109.1    PZC71197.1    KU680280    ANI21986.1    KPJ00048.1    JQ070196    AEW43112.1    KF777110    AHY99681.1    JQ070191    AEW43107.1    JQ070201    AEW43117.1    PZC71196.1    JQ070198    AEW43114.1    PZC71198.1    SOQ44549.1    PZC71202.1    PZC71200.1    PZC72371.1    JQ070238    AEW43154.1    NWSH01000435    PCG76447.1    KQ459937    KPJ19195.1    PZC72369.1    KU680286    ANI21992.1    JQ070192    AEW43108.1    KU214506    AMK97472.1    KY202945    AUC64289.1    PZC72370.1    KU680291    ANI21997.1    KU680285    ANI21991.1    KU680290    ANI21996.1    ODYU01001030    SOQ36683.1    KPJ00042.1    KPJ00041.1    JQ070237    AEW43153.1    PZC72372.1    JQ070203    AEW43119.1    GEYN01000099    JAV02030.1    BABH01029238    BABH01029239    BABH01029240    PCG76446.1    KQ459680    KPJ20473.1    GQ915324    ACZ97418.2    KPJ00055.1    KPJ00049.1   

Proteomes

UP000005204    UP000037510    UP000218220    UP000053268    UP000053240   

PRIDE

G9LPS4    H9JWB9    G9LPS8    G9LPS7    H9JWE6    G9LPS9    + More
B7TZA3    G9LPS3    H9JWB7    G9LPS6    G9LPS5    G9LPS2    F1DG68    Q1HPX7    G9LPT1    H9JWB6    G9LPT0    H9JWC2   

Pfam

PF00201   UDPGT        + More
PF00089   Trypsin

Interpro

IPR002213   UDP_glucos_trans        + More
IPR035595   UDP_glycos_trans_CS       
IPR006326   UDPGT_MGT       
IPR033116   TRYPSIN_SER       
IPR001314   Peptidase_S1A       
IPR009003   Peptidase_S1_PA       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       

SUPFAM

SSF50494   SSF50494       

CDD

cd00190  Tryp_SPc

ProteinModelPortal

G9LPS4   H9JWB9   G9LPS8   G9LPS7   H9JWE6   G9LPS9   + More
B7TZA3   G9LPS3   H9JWB7   G9LPS6   G9LPS5   G9LPS2   F1DG68   Q1HPX7   M4M1W9   A0A2W1BL20   G9LPP3   A0A0L7LF59   A0A191T2J5   A0A2H1WTF5   A0A191T1L8   G9LPP5   A0A024AH14   A0A2H1W0F9   A0A2H4WB73   A0A191T1L3   A0A2A4IVU8   A0A1L8D6T8   A0A2W1B475   A0A2H1VUS4   A0A2H1VU94   A0A191T1L2   A0A2H1W7S2   A0A2I6RJL8   G9LPN7   G9LPP7   A0A2W1BA70   A0A2W1BHP8   A0A024AGL3   A0A2W1B485   A0A2W1BQP4   A0A0N1IB27   A0A191T2J2   G9LPN3   A0A2W1B8G2   G9LPN8   A0A2W1BEA5   A0A2W1B3V4   A0A2H1WSA7   A0A2W1BBH1   A0A2W1B675   A0A024AG00   A0A191T1K4   A0A2W1B7N5   A0A191T1K8   G9LPP0   G9LPN2   A0A2W1B8D3   G9LPP2   G9LPN6   A0A2W1BCY8   A0A191T2F8   A0A0N1I2R8   G9LPN9   A0A024AGF9   G9LPN4   G9LPP4   A0A2W1BE55   G9LPP1   A0A2W1B6A2   A0A2H1VUM4   A0A2W1B3X2   A0A2W1BEB8   A0A2W1BDA5   G9LPT1   A0A2A4JWQ0   A0A0N0PE43   A0A2W1B9W6   A0A191T1M4   G9LPN5   A0A140EA35   A0A2H4WB75   A0A2W1BHY3   A0A191T1N0   H9JWB6   A0A191T2G1   A0A191T2G3   A0A2H1V761   A0A0N0P9C8   A0A0N1ICS6   G9LPT0   A0A2W1BAD4   G9LPP6   A0A1L8D6R8   H9JWC2   A0A2A4JXE4   A0A0N1IQG9   D2JLK8   A0A0N1ICT4   A0A0N0P9D3  

PDB

2O6L     E-value=7.44255e-26,     Score=292

KEGG

100862803    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT33D3; UDP-glycosyltransferase UGT33D3

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0015020   GO:0016758   GO:0016999   GO:0004252   GO:0008152   GO:0008270   GO:0043565   GO:0005839   GO:0051603   GO:0046835   GO:0006281   GO:0006259  

Subcellular location

Membrane  

Length:

463

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.791150000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.03592

outside

1  -  463

 

 

Pi

206.546027

Theta

174.135189

Tajima's D

0.585516

CLR

116.362563

CSRT

0.539473026348683

Interpretation

Uncertain