SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO16417
Pre Gene Modal
BGIBMGA013834
Annotation
UDP-glycosyltransferase_UGT340C2_precursor_[Bombyx_mori]
Full name
UDP-glucuronosyltransferase       + More
Ecdysteroid UDP-glucosyltransferase      
Location in the cell
PlasmaMembrane   Reliability : 2.298
 

Sequence

CDS
ATGAAGTCAATAGCTTTATACTTCTTGTTATCAATTTTCGGTGTAGAATCGGCTAGGATTTTAGGAGTGTTTCCTATGCCATCAATAAGTCATCAAGTTGTCTTTCGAGCTCTGAGCATGGAGCTAGCCAGGAGAGGACACGAATTGGTGATCATAACGACAGACCCTGCCCTGCCAAAGAATAGACCGAAAGATAATATTACTGAGATAGATATTAGTCGTTCTTACCAACTTTTGCGTAAATTCGATGAATATGCTGAAAAAACTCAGCCGATTCAGAAACGTGGAGTGATTTCTGGAGTGGAAATAATGATCAGTGAGCATGCTGCAGGGGCCATGTTTATGCTGATGGCGGAAGTATTCAACAGCGAAGAAGTGAACCAGTTACTTCAAGACAAGAACCAGAAGTTCGATTTAATCATATCAGAAGCCATTATGAGTTTCCATTTGATAATCGGGAAAATCTTCAACGCGCCAGTTATTCTATTCTCGTCTTTGTATGGTCTTCCTGAAACTTTCGAAACAGTGGGGGCCGTGACGCGCCATCCGATTTTATATCCCCATTTATTTAGGAATAAGTTTACAGATTTAACATTATTCGAGAAAATCCGCGAGGTCTACTATGAGGCTCGATTGACCTTGCTGTATTGGGGTCTTCAGAATGCTGAAAATAATTACCTGAAGTCCCGTTTCGGAGAGAACGCACCTACAGTACAACAATTAAGGGAGAATGTCTGTATGGTGTTTTTGAATTCGTTCCCTCTCTTTGATAACAACCGACCGGTGCCACCTAATGTGGTGTATTTGGGAGCTTTGCACTTGCAACCTGTTAAGGAATTGCCTGAGGACCTAAAGACATATCTGGATAACTCTAAACGTGGTGTGGTATACGCCAGCTTGGGGACGAACGTGCGTGCTTCAGCCATGAGCAAGGAGTTTCTGGAAACTTTCATCAAAGCTTTCGAAGCTCTTCCCTATGACATATTGTGGAAAATCGATGGAGATGACATAAAGGCGTTTCCAAAGAATGTTCGTGTGCAAAAATGGTTCCCCCAAAGAGATTTATTAGTTCATCCAAACATTGTGGCCTTTGTCACACAAGGCGGGCTCCAATCAACTGATGAAGCGATTGATGCCGGAGTACCTCTAGTCGGAATACCTTTAATCGCAGATCAGTGGTACAATGTTAATAAATACAAAGAACTTGGAATCGGTATCAGTTTGGATTCATTCACAGTTAATGCTGAAGAATTGGCTCAAGCTGTCAAAACTGTGGCTACAGACAAAAGTTTTAAGAACAACATCGCGAAAATCAAAACCCTGATGCACGATCAGCCTCTGAAGCCATTAGAACGCGCGGTCTGGTGGACGGAGCATGTTCTTCGAAACGGAGGATCCAAACACCTTCGTTCGCCAGCGGCCAACATGAATTACTCAGAATATTTAATGTTAGACGTTGTCTTAGCCTTATTATTTTTATTCTTTACTGTGATATCGATACTCGCTCTCATTGCGTACAAGCTTTTTGGTATATTAAAGAAAATGACCTTTAGTGGTAAATTAAAAAGTAGCTGA
Protein
MKSIALYFLLSIFGVESARILGVFPMPSISHQVVFRALSMELARRGHELVIITTDPALPKNRPKDNITEIDISRSYQLLRKFDEYAEKTQPIQKRGVISGVEIMISEHAAGAMFMLMAEVFNSEEVNQLLQDKNQKFDLIISEAIMSFHLIIGKIFNAPVILFSSLYGLPETFETVGAVTRHPILYPHLFRNKFTDLTLFEKIREVYYEARLTLLYWGLQNAENNYLKSRFGENAPTVQQLRENVCMVFLNSFPLFDNNRPVPPNVVYLGALHLQPVKELPEDLKTYLDNSKRGVVYASLGTNVRASAMSKEFLETFIKAFEALPYDILWKIDGDDIKAFPKNVRVQKWFPQRDLLVHPNIVAFVTQGGLQSTDEAIDAGVPLVGIPLIADQWYNVNKYKELGIGISLDSFTVNAEELAQAVKTVATDKSFKNNIAKIKTLMHDQPLKPLERAVWWTEHVLRNGGSKHLRSPAANMNYSEYLMLDVVLALLFLFFTVISILALIAYKLFGILKKMTFSGKLKSS

Summary

Description
Catalyzes the transfer of glucose from UDP-glucose to ecdysteroids which are insect molting hormones.
Catalytic Activity
glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP
Similarity
Belongs to the UDP-glycosyltransferase family.
Feature
chain  UDP-glucuronosyltransferase
EC Number
2.4.1.17
2.4.1.-
EMBL
JQ070243    AEW43159.1    BABH01029259    JQ070242    AEW43158.1    GEYN01000078    + More
JAV02051.1    KY202924    AUC64268.1    KY202939    AUC64283.1    RSAL01000157    RVE45575.1    KY202938    AUC64282.1    KY202941    AUC64285.1    GEYN01000077    JAV02052.1    GEYN01000081    JAV02048.1    JTDY01002875    KOB70560.1    RVE45576.1    KZ150193    PZC72373.1    JQ070200    AEW43116.1    ODYU01006890    SOQ49139.1    JQ747500    AGG36457.1    JQ070231    AEW43147.1    PZC72369.1    JQ070192    AEW43108.1    BABH01029271    JQ070236    AEW43152.1    KU214506    AMK97472.1    FJ418685    ACJ48963.1    JQ070201    AEW43117.1    KU680289    ANI21995.1    KU680291    ANI21997.1    KU680282    ANI21988.1    JQ070194    AEW43110.1    NWSH01000435    PCG76447.1    KU680281    ANI21987.1    KQ459547    KPJ00043.1    JQ070197    AEW43113.1    JQ070198    AEW43114.1    KZ150360    PZC71197.1    PZC72371.1    PZC71193.1    PZC71202.1    KF777110    AHY99681.1    JQ070202    AEW43118.1    KU680283    ANI21989.1    ODYU01004546    SOQ44549.1    JQ070233    AEW43149.1    ODYU01010933    SOQ56350.1    KU680290    ANI21996.1    BABH01029260    KU680284    ANI21990.1    KF777109    AHY99680.1    KU680280    ANI21986.1    KU680288    ANI21994.1    PZC71199.1    JQ070196    AEW43112.1    PZC71189.1    PZC71200.1    KPJ00042.1    KQ459937    KPJ19195.1    JQ070193    AEW43109.1    JQ070189    AEW43105.1    KF777111    AHY99682.1    KZ150704    PZC70374.1    PZC71196.1    KY202933    AUC64277.1    PZC71192.1    PZC71191.1    KY202945    AUC64289.1    JQ070238    AEW43154.1    PZC71190.1    PZC72370.1    JQ070232    AEW43148.1    PZC70375.1    KPJ00041.1    GEYN01000079    JAV02050.1    PZC71201.1    JQ070195    AEW43111.1    PZC71194.1    KY304474    AUN86405.1    DQ443275    ABF51364.1    NWSH01005967    PCG63789.1    JQ070190    AEW43106.1    KPJ00048.1    MH124167    AXU41563.1    KF777112    AHY99683.1    PZC71195.1    ODYU01001030    SOQ36683.1    JQ070235    AEW43151.1    SOQ44548.1    KU680287    ANI21993.1    JQ070199    AEW43115.1    KU680286    ANI21992.1    HQ833816    ADY17534.1    JQ070229    AEW43145.1    JQ070191    AEW43107.1    JQ070234    AEW43150.1    ODYU01004485    SOQ44409.1    BABH01029273    BABH01029274    PZC71198.1    AY394490    AAR28909.1    KU680285    ANI21991.1    ODYU01010294    SOQ55304.1    JQ070230    AEW43146.1    ODYU01005543    SOQ46493.1   
Pfam
PF00201   UDPGT
Interpro
IPR002213   UDP_glucos_trans        + More
IPR035595   UDP_glycos_trans_CS       
IPR006326   UDPGT_MGT       
IPR016224   Ecdysteroid_UDP-Glc_Trfase       
PDB
2O6L     E-value=2.23856e-27,     Score=305

Ontologies

Topology

Subcellular location
Membrane  
SignalP
Position:   1 - 17,         Likelihood:  0.959017
 
 
Length:
524
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
31.17238
Exp number, first 60 AAs:
6.2206
Total prob of N-in:
0.25406
outside
1  -  485
TMhelix
486  -  508
inside
509  -  524
 
 

Population Genetic Test Statistics

Pi
199.344303
Theta
159.292021
Tajima's D
0.74547
CLR
0.721074
CSRT
0.581270936453177
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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