Gene

KWMTBOMO16340  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013786

Annotation

hypothetical_protein_KGM_19668_[Danaus_plexippus]

Location

Bomo_Chr28(+):5652219-5658451      View in EpiBrowser

Full name

CDK-activating kinase assembly factor MAT1      

Alternative Name

CDK7/cyclin-H assembly factor
Menage a trois
RING finger protein MAT1

Location in the cell

Nuclear   Reliability : 3.812

CDS

ATGGATGACCAAGCTTGTCCTCGTTGTAAAACAACAAAATACAGAAATCCGTCGCTAAAGTTAATGGTAAATGTTTGCGGCCACGTTTTGTGTGAAAACTGTGTTGATTTACTGTTTTTAAAAGGCTCAGGTTCTTGTCCGGATTGCAACATAGTATTACGCAGAGGAAATTTTAGGGTTCAGTTATTCGAAGATCCGATGGTGGAAAAGGAAGTAGATATAAGAAAACGCGTATTACGAGATTACAACAAAAAAGAGGAAGATTTTAATTCGTTAAGAGAATATAATGATTATTTAGAAGAAATTGAAACCATCGTATACAATTTAACAAATAATATAGACATAGTAGAAACTAATAAAAGGATAGAACAGTACAAAAAAGAAAACAAGGAATTGATAATGAAAAATAAAGCCAAACTTGGAAGAAAAGCAATTGAATTAGAAGAATTATTAGAGAAAGAGAAAGAGTATGAAGAGCTCAGAAGACAAGAGCTGTCTCGACTAGAACAAGAAGCGAAAAGAAAGAAGATTCGCGAGAAGGAAGCTCTCATTGATGAATTAATGTTTGCAGAGGGCAATGCCAAAGATATTCTCAATACGTTTGCTCAGACTGTAGCAAATAAAAAAGAGGAGGAAGAGGTTGTCCCTATGGTAACTCAATTCTCTACTGGAGTGCAATTCACTAGAGGGTCGACAAATCAACCTATTCCAATAATAGAAGAAGGACCAATGTATAAATATGAACCATTAGCCATCCCGGATAGATGTGGACCGGATCCGCCAATGATCAAAGAAATAATTCAAAATGGTTTTCTGAAGCATGTGAGGGCTGAAAACGAGACCGAGAAGGCTGGGGGTTACACGTCAACATTACCATGTTTAAGGGCATTACAGGATGCACTCTCGGGATTGTATCACGCCAGCTGA

Protein

MDDQACPRCKTTKYRNPSLKLMVNVCGHVLCENCVDLLFLKGSGSCPDCNIVLRRGNFRVQLFEDPMVEKEVDIRKRVLRDYNKKEEDFNSLREYNDYLEEIETIVYNLTNNIDIVETNKRIEQYKKENKELIMKNKAKLGRKAIELEELLEKEKEYEELRRQELSRLEQEAKRKKIREKEALIDELMFAEGNAKDILNTFAQTVANKKEEEEVVPMVTQFSTGVQFTRGSTNQPIPIIEEGPMYKYEPLAIPDRCGPDPPMIKEIIQNGFLKHVRAENETEKAGGYTSTLPCLRALQDALSGLYHAS

Description

Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

Subunit

Associates with CDK7 and cyclin H.

Uniprot

A0A212EZP9   A0A2W1BMR1   A0A2H1WTW5   H9JW72   A0A2A4J761   A0A0N1IDW9   + More
A0A194PWI3   A0A0L7QX65   A0A2J7Q642   A0A088A0Q4   A0A2A3EPW9   A0A154P1E2   A0A1B0CU32   A0A195DPD0   A0A195BCK8   A0A158NFI5   A0A0M9AE14   A0A151JY57   E2BZE4   A0A0C9QZ94   A0A151WP50   A0A0T6BFT4   A0A195CV45   A0A1B6DUT4   A0A067R1E3   K7J8Q9   A0A232F3X0   A0A1B0G6P6   A0A1A9YB32   E9IGK4   A0A1A9ZX64   A0A1A9VY10   A0A1I8PHK8   A0A1I8MUW5   A0A0L0CBP7   A0A1B0BHL2   A0A026VVR6   F4X185   A0A1Y1MRU0   Q8SX08   Q7KPG8   A0A0J9R9Y8   A0A1A9WYJ6   A0A1B6M6R1   A0A1B6H2K9   A0A1B6I0X2   B4P839   B4GG89   B3NN56   A0A0A1X501   Q28XJ6   B3MIK0   A0A034WLF3   A0A0K8VE50   A0A1W4VS12   A0A2R7VVM3   A0A336L0K7   E2A1X0   D6WRL6   E0VAF8   W8BK45   N6TT49   B4LKP0   A0A1Q3F8I4   A0A3B0J0H7   T1GR61   J3JVF6   A0A0A9XRU3   B4J7T4   B0W2W5   B4KQ80   A0A0M4EB07   A0A0V0GC94   A0A0P4VR54   R4G445   A0A1B0GMR9   A0A069DRV3   A0A182J613   B4MNX9   Q16XK0   A0A182GL64   A0A182LMI0   Q7PWE7   A0A182TY02   A0A084WFU3   A0A182V4X7   U5EW86   A0A182QSS7   B4HMT9   A0A182KFX4   A0A182NZG4   A0A182WXN8   A0A2M4AYL4   A0A182I7K3   V4ART5   A0A182LYA6   A0A182Y0J0   W5JD02   A0A182NBL2   B7Q3X0  

Pubmed

22118469    28756777    19121390    26354079    21347285    20798317    + More
24845553    20075255    28648823    21282665    25315136    26108605    24508170    30249741    21719571    28004739    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    17994087    17550304    25830018    15632085    25348373    18362917    19820115    20566863    24495485    23537049    22516182    25401762    27129103    26334808    17510324    26483478    20966253    12364791    14747013    17210077    24438588    23254933    25244985    20920257    23761445   

EMBL

AGBW02011249    OWR46937.1    KZ150137    PZC72973.1    ODYU01010975    SOQ56422.1    + More
BABH01025370    BABH01025371    NWSH01002936    PCG67253.1    KQ461053    KPJ09937.1    KQ459588    KPI97731.1    KQ414705    KOC63185.1    NEVH01017540    PNF24060.1    KZ288201    PBC33554.1    KQ434783    KZC04950.1    AJWK01028358    KQ980662    KYN14701.1    KQ976514    KYM82288.1    ADTU01014522    KQ435687    KOX81403.1    KQ981494    KYN40942.1    GL451589    EFN78954.1    GBYB01001050    JAG70817.1    KQ982893    KYQ49587.1    LJIG01000736    KRT86204.1    KQ977279    KYN04397.1    GEDC01007865    JAS29433.1    KK852779    KDR16707.1    NNAY01001022    OXU25451.1    CCAG010015982    GL763048    EFZ20318.1    JRES01000622    KNC29838.1    JXJN01014424    KK108092    QOIP01000005    EZA46924.1    RLU22566.1    GL888528    EGI59757.1    GEZM01023422    JAV88393.1    AY094918    AAM11271.1    AF071227    AE013599    BT025213    AAC25575.1    AAF58758.1    ABF17904.1    CM002911    KMY92847.1    GEBQ01008361    JAT31616.1    GECZ01000850    JAS68919.1    GECU01027140    JAS80566.1    CM000158    EDW90086.1    CH479183    EDW35509.1    CH954179    EDV56576.1    GBXI01008492    JAD05800.1    CM000071    EAL26320.2    CH902619    EDV38076.1    GAKP01003972    JAC54980.1    GDHF01033925    GDHF01031488    GDHF01025073    GDHF01019785    GDHF01015514    GDHF01007155    JAI18389.1    JAI20826.1    JAI27241.1    JAI32529.1    JAI36800.1    JAI45159.1    KK854085    PTY10951.1    UFQS01000758    UFQT01000758    UFQT01000782    SSX06690.1    SSX27036.1    SSX27189.1    GL435845    EFN72564.1    KQ971354    EFA07055.2    DS235006    EEB10364.1    GAMC01012934    JAB93621.1    APGK01019946    KB740150    KB632173    ENN81238.1    ERL89563.1    CH940648    EDW61763.1    GFDL01011206    JAV23839.1    OUUW01000001    SPP74147.1    CAQQ02004896    BT127224    AEE62186.1    GBHO01020138    GBHO01020137    GBRD01004484    JAG23466.1    JAG23467.1    JAG61337.1    CH916367    EDW01140.1    DS231829    EDS30324.1    CH933808    EDW09208.1    CP012524    ALC40627.1    GECL01000611    JAP05513.1    GDKW01001576    JAI55019.1    ACPB03001903    GAHY01001665    JAA75845.1    AJVK01026443    GBGD01002214    JAC86675.1    CH963848    EDW73818.1    CH477537    EAT39359.1    JXUM01013656    KQ560381    KXJ82700.1    AAAB01008984    EAA14858.3    ATLV01023404    KE525343    KFB49087.1    GANO01000676    JAB59195.1    AXCN02000676    CH480816    EDW47301.1    GGFK01012491    MBW45812.1    APCN01003414    KB200869    ESO99952.1    AXCM01003792    ADMH02001516    ETN62227.1    ABJB010654288    ABJB010954334    ABJB011026554    DS852491    EEC13542.1   

Proteomes

UP000007151    UP000005204    UP000218220    UP000053240    UP000053268    UP000053825    + More
UP000235965    UP000005203    UP000242457    UP000076502    UP000092461    UP000078492    UP000078540    UP000005205    UP000053105    UP000078541    UP000008237    UP000075809    UP000078542    UP000027135    UP000002358    UP000215335    UP000092444    UP000092443    UP000092445    UP000078200    UP000095300    UP000095301    UP000037069    UP000092460    UP000053097    UP000279307    UP000007755    UP000000803    UP000091820    UP000002282    UP000008744    UP000008711    UP000001819    UP000007801    UP000192221    UP000000311    UP000007266    UP000009046    UP000019118    UP000030742    UP000008792    UP000268350    UP000015102    UP000001070    UP000002320    UP000009192    UP000092553    UP000015103    UP000092462    UP000075880    UP000007798    UP000008820    UP000069940    UP000249989    UP000075882    UP000007062    UP000075902    UP000030765    UP000075903    UP000075886    UP000001292    UP000075881    UP000075885    UP000076407    UP000075840    UP000030746    UP000075883    UP000076408    UP000000673    UP000075884    UP000001555   

PRIDE

H9JW72    Q8SX08    Q7KPG8   

Pfam

PF17121   zf-C3HC4_5        + More
PF06391   MAT1

Interpro

IPR004575   MAT1/Tfb3        + More
IPR001841   Znf_RING       
IPR013083   Znf_RING/FYVE/PHD       
IPR015877   Cdk-activating_kinase_MAT1_cen       
IPR017907   Znf_RING_CS       
IPR036388   WH-like_DNA-bd_sf       
IPR009057   Homeobox-like_sf       

SUPFAM

SSF46689   SSF46689       

Gene 3D

3.30.40.10     1.10.10.10    

ProteinModelPortal

A0A212EZP9   A0A2W1BMR1   A0A2H1WTW5   H9JW72   A0A2A4J761   A0A0N1IDW9   + More
A0A194PWI3   A0A0L7QX65   A0A2J7Q642   A0A088A0Q4   A0A2A3EPW9   A0A154P1E2   A0A1B0CU32   A0A195DPD0   A0A195BCK8   A0A158NFI5   A0A0M9AE14   A0A151JY57   E2BZE4   A0A0C9QZ94   A0A151WP50   A0A0T6BFT4   A0A195CV45   A0A1B6DUT4   A0A067R1E3   K7J8Q9   A0A232F3X0   A0A1B0G6P6   A0A1A9YB32   E9IGK4   A0A1A9ZX64   A0A1A9VY10   A0A1I8PHK8   A0A1I8MUW5   A0A0L0CBP7   A0A1B0BHL2   A0A026VVR6   F4X185   A0A1Y1MRU0   Q8SX08   Q7KPG8   A0A0J9R9Y8   A0A1A9WYJ6   A0A1B6M6R1   A0A1B6H2K9   A0A1B6I0X2   B4P839   B4GG89   B3NN56   A0A0A1X501   Q28XJ6   B3MIK0   A0A034WLF3   A0A0K8VE50   A0A1W4VS12   A0A2R7VVM3   A0A336L0K7   E2A1X0   D6WRL6   E0VAF8   W8BK45   N6TT49   B4LKP0   A0A1Q3F8I4   A0A3B0J0H7   T1GR61   J3JVF6   A0A0A9XRU3   B4J7T4   B0W2W5   B4KQ80   A0A0M4EB07   A0A0V0GC94   A0A0P4VR54   R4G445   A0A1B0GMR9   A0A069DRV3   A0A182J613   B4MNX9   Q16XK0   A0A182GL64   A0A182LMI0   Q7PWE7   A0A182TY02   A0A084WFU3   A0A182V4X7   U5EW86   A0A182QSS7   B4HMT9   A0A182KFX4   A0A182NZG4   A0A182WXN8   A0A2M4AYL4   A0A182I7K3   V4ART5   A0A182LYA6   A0A182Y0J0   W5JD02   A0A182NBL2   B7Q3X0  

PDB

6O9M     E-value=6.26643e-72,     Score=687

KEGG

101747108    K10842 CDK-activating kinase assembly factor MAT1 | (RefSeq) CDK-activating kinase assembly factor M

PATHWAY

03022    Basal transcription factors - Bombyx mori (domestic silkworm)
03420    Nucleotide excision repair - Bombyx mori (domestic silkworm)

GO

GO:0016301   GO:0061575   GO:0006289   GO:0005675   GO:0007049   GO:0003677   GO:0032806   GO:0006468   GO:0000079   GO:0006367   GO:0008270   GO:0016740   GO:0008353   GO:0004693   GO:0006357   GO:0016874   GO:0005634   GO:0005515   GO:0033557   GO:0005839   GO:0051603   GO:0046835   GO:0006281   GO:0006259   GO:0045737  

PANTHER

PTHR12683:SF13  

Subcellular location

Nucleus  

Length:

308

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.31773

Exp number, first 60 AAs:

0.31752

Total prob of N-in:

0.11506

outside

1  -  308

 

 

Pi

200.451982

Theta

160.870852

Tajima's D

1.004264

CLR

0

CSRT

0.660866956652167

Interpretation

Uncertain