Gene

KWMTBOMO16336

Annotation

reverse_transcriptase_[Lasius_niger]

Location

Bomo_Chr28(-):5624302-5628518      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon X-element      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 3.541

CDS

ATGGAAAGTCAGAGTAATGAGTGTGATTTGTCATGCGCCCCGGCTAACCCCCGGCGCCCTCTGGTACCCGGGCCGGAGGGTGTGAAATCTGCTACCGAAGACGGCATAGAAGTGGCAACCCAGGCTTCTATGCCAGTAAATGCTACTGGTCAAAAGAAGTTAGTTCAGCAGGCATTCCATCCTAGCCTCTTTTTAAATCGGCCAAGAAGTTCGTCCCTAGGAAGTCTTTCGAACCAGGCGTCTGCTAAAGAAAAATGTAGTCAAAGCTCTGAGGACTCTGCCGAAACGCTAAGAGATACCACATGCCCACCACCATGGCAAAGAGTTCCTGTAAGCAGAGGTGTCAAAAGAAAGAAAACATCTTACGGTCCAGTCCCAGAATCTGTGATAACCTCAAATAAATTTAGTGGTCTTCAAATTGATCTAACAGACGAAGACTCTGAAACTACTACGGTTAAAAAAACAAGTAAACCGCCCCCAATTATTCTATATGGGGTCGACGACATTAACAAACTTACTGAAATGCTAGAAACTGTCGCGGACGTGACAGAGTTCACATTCAAGATCACTAATCGAAACCAACTAAGGATGAACTGTGTTAACATGGATGTGTATAAAAGAATCCTTACCCTAGTGAGAGAAAAGGGGCTAATAGGCCACACTTTCAATCGAAAGGATGAAAGATGCCTCAGAATTGTCATACGGAACTTACACCCTTCTACACCCATTGACATTATCAAAGAAGAAATAGAAGCCACCGGAAATATTGTTAAGGGAGAAATAATTAATGCGAAATTCGGCCCCGAAAAGAAGCCTACTTCCACCTTTTTCGTGAATCTCTTGCCCGGCCCAAACAATAAAGCTGCTAAAGACCTTAAATTTATATACCATCAGTCTGTTGTTATCGAAGACCCGAGGAAAAGAAGGTCTATAATCCAGTGTCACAGATGCCAGCAATACGGGCACTCTAAGAATTACTGTATGCGACCTCCTCGTTGTGTTAAATGCGGCCAATCCCATAAGACCTCCGATTGCGATAAAAAAGACCGTAATACACCTGCGCTTTGTGCGCTCTGTAGTGGACCACATCCAGCCAACTATAAAGGATGCGAGCATAATTTAGATGTGCTGCTAATCTCCGAGGCTCACTGTACCGCGTCCTCTAGTATAAAATTCAAAAACTATGTGTGTTACGTCACTACTCACCCTGATGGTACTGGACATGCAGGAACAGCAATAATAGTACGAAAATCCATTAAACACCACCCAATGCCTGGCTACAAAACCGATCACATTCAAGCCACTACAATACTAATTGAAGACAAAAGTGGTTGTTTTAACTTGTCAGCAATATACTGTCCGCCAAAGCATAAAATCATGGGGGATATGTTCATAGATTTCTTCCAAAGTCTCGGAAATCGCTTTGTCGTGGGTGGAGACTGGAATGCAAAATGCACTTACTGGGGCTCGAGACTAACGACCACAAGAGGACGACAGTTGAAGCTCTGTGTGGATGATTGCAAATTAACCACAGTTTCAACTGGGGAACCGACTTACTGGCCCTCAGACCCAAATAAAATTCCAGACCTATTGGACTTCTTTATTTTGAAAGGGTTTTCAACACACTATATCAAATCTGAGTCGTGCTATGACAGCTCCACAGACCACACTCCAGTCCTGCTAAATTTGAGTACAATGGTGATAGAATATACGACACCTGAAAAATTGAGTAATAAAAGCACTGACTGGAAATCGTTCAGGGAAACCCTTGATGAAAAAATTGACCTGAAAGTAGCTCTGAAAACACCTGATGATATTGAAAATGCGACTAGATACATAACTAATCTGATCCAAGAAGCATGCTGGGTGTCCACGCCTGAAGAAGAGTCTGTAAAAACTCGTATAAACTATCCATTGGAAGTCAGAAAGGCAGTACTGGAAAAGAGGAGGCTTAGAAGAGTCTGGCACCAAAGCAGATTAGAAGCAGACAAGAAAGCGCTGTATAGGAGTGCGGTTCAACTAAAAGAAATACTGAACAACTGGCACAATAAAACGTTGGAGGATCGTCTCGTGACACTAACAGCCACTGCAGCAACTAATTACTCGTTGTGGAAATTCACCAAGAATTATAGCAGACCTCAGTCATTCAAACCTCCGATAAAAACCATGAATGGTTGGGCGCGAACATCTCAAGAAAAAGCAAACGCATTCGCTCAACATCTTGAATCAGTTTTTAAACCAAATGCTGACATAGATTTAGTACATGAGGAACATATCAATGAAATTCTGCTACAAGACTTCCAAATGCTACCCCCACAGCGGCCAGTCACAGTACGCGAAGTTTGGAGAGTTATATCAAAACTACAGGATAAAAAGGCTCCCGGATATGATCTTATAACCAAGGAGATATTAAAACAAATTCCAAGGAAGGTGGTAGTGTTCCTGACTTCACTCTATAATAGCATACTAAGAGTCCAGTATTTTCCAATGGCCTGGAAAGTATCTCACATAATTATGATTCACAAGATGGGCAAACCACCCAATGAAGTATCCTCATACCGACCTATAAGCTTGCTGCCAATACTTTCCAAAGTTTTCGAGAAGCTCCTGAAAGGTAGACTTGTCCCAATCCTCAATGACGAAAAAATCATTCCTGATCATCAATTTGGGTTTAGACGAAATCATGGCACGGTCGAACAAGTTCACAGAGTCTGTGAAAAAATACGCAAAAGTTTGGAAGAAAAACTCTACTGCTCCTCGGCGTTTCTAGATATACAGCAGGCCTTTGATAAAGTGTGGCATAAAGGCCTCCTGTATAAATTAAAGGCAGCGCTACCTCATCAGTATTATTGTCTGCTAAAATCGTATCTCGCAGACAGAATATTCCAGGTGAAAGAAGGGGATTCTTTGTCACGATTCTGCGATATCTCAGCAGGTGTACCACAGGGATCAGTCCTGGGACCACTATTATATACTATATACACTGCTGACCTACCTGAGGTTAATGATGTTACCACTGCAACATTCGCCGATGATACTGCAATATTGGTGAGTCACACGGATCGTTTTGTAGCATCACAAAGATTGCAAAAAGGTCTTGATAAAATATCCACATGGCTACACAAGTGGCGAATAAAAGCCAGTGCAAACAAGTCGGTACATGTTACATTCACATTGCGAAAAGGTGATTGTCCACCTGTCCATGTTAATAACGCTATATTGCCCCATCAAGACAATGTAAGATACCTGGGAATGCACTTGGACCGCCGCCTAACATGGAAACACCACATTCAAACTAAGAGACAGGAACTAAACATCCGATACAAAAATCTCCATTGGCTGTTGGGACGTAACAGCAAGCTGAGTGTTGACAACAAACTTTTAATTTACAAAGTTATCCTTAAGCCAGTTTGGCTGTACGGAATCGAATTATGGGGTAGCGCCTGCAATTCGAATATCAGTATTATACAAAGAATGCAAAACTGTATCTTGCGCTCCATAAGTGGTGTTCCGTGGTTGGTCACAAACACTGAAATACACAAAGAACTAGGGATGCCTACAATAATGCAGGAAATCGTAAAATTTAAACAAAAACACCACGAAAGACTGGAAAAGCACCCAAACAATCTGGCTGCCGCCTTGAAAAAACGAAGTTACGGTAAAAGGCTCAAGAGAAAAGACGTCATATAG

Protein

MESQSNECDLSCAPANPRRPLVPGPEGVKSATEDGIEVATQASMPVNATGQKKLVQQAFHPSLFLNRPRSSSLGSLSNQASAKEKCSQSSEDSAETLRDTTCPPPWQRVPVSRGVKRKKTSYGPVPESVITSNKFSGLQIDLTDEDSETTTVKKTSKPPPIILYGVDDINKLTEMLETVADVTEFTFKITNRNQLRMNCVNMDVYKRILTLVREKGLIGHTFNRKDERCLRIVIRNLHPSTPIDIIKEEIEATGNIVKGEIINAKFGPEKKPTSTFFVNLLPGPNNKAAKDLKFIYHQSVVIEDPRKRRSIIQCHRCQQYGHSKNYCMRPPRCVKCGQSHKTSDCDKKDRNTPALCALCSGPHPANYKGCEHNLDVLLISEAHCTASSSIKFKNYVCYVTTHPDGTGHAGTAIIVRKSIKHHPMPGYKTDHIQATTILIEDKSGCFNLSAIYCPPKHKIMGDMFIDFFQSLGNRFVVGGDWNAKCTYWGSRLTTTRGRQLKLCVDDCKLTTVSTGEPTYWPSDPNKIPDLLDFFILKGFSTHYIKSESCYDSSTDHTPVLLNLSTMVIEYTTPEKLSNKSTDWKSFRETLDEKIDLKVALKTPDDIENATRYITNLIQEACWVSTPEEESVKTRINYPLEVRKAVLEKRRLRRVWHQSRLEADKKALYRSAVQLKEILNNWHNKTLEDRLVTLTATAATNYSLWKFTKNYSRPQSFKPPIKTMNGWARTSQEKANAFAQHLESVFKPNADIDLVHEEHINEILLQDFQMLPPQRPVTVREVWRVISKLQDKKAPGYDLITKEILKQIPRKVVVFLTSLYNSILRVQYFPMAWKVSHIIMIHKMGKPPNEVSSYRPISLLPILSKVFEKLLKGRLVPILNDEKIIPDHQFGFRRNHGTVEQVHRVCEKIRKSLEEKLYCSSAFLDIQQAFDKVWHKGLLYKLKAALPHQYYCLLKSYLADRIFQVKEGDSLSRFCDISAGVPQGSVLGPLLYTIYTADLPEVNDVTTATFADDTAILVSHTDRFVASQRLQKGLDKISTWLHKWRIKASANKSVHVTFTLRKGDCPPVHVNNAILPHQDNVRYLGMHLDRRLTWKHHIQTKRQELNIRYKNLHWLLGRNSKLSVDNKLLIYKVILKPVWLYGIELWGSACNSNISIIQRMQNCILRSISGVPWLVTNTEIHKELGMPTIMQEIVKFKQKHHERLEKHPNNLAAALKKRSYGKRLKRKDVI

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon X-element

Uniprot

J9LYS0   A0A2J7R7D0   A0A2J7Q0S7   A0A2J7RD70   A0A142LX26   J9M0H4   + More
A0A224X6U5   Q6R811   Q04135   Q961V7   A0A0J7K7J8   A0A034VFD2   A0A2S2N814   A0A069DX78   A0A224X6R6   A0A2S2PJG2   A0A2S2N6Q7   J9LBQ6   A0A2S2P6S3   A0A224X6W2   A0A2S2NGV8   A0A224X6S1   A0A224XIB0   A0A023F0I3   A0A2S2NH02   A0A2S2P698   A0A2H8TKI9   A0A2S2PHL7   A0A2S2R9D4   A0A2S2QEE0   A0A2S2NKC3   A0A2S2P3X8   Q9NBX4   J9LMA3  

EC Number

2.7.7.49

Pubmed

25527032    14745026    1705654    25348373    26334808    25474469    + More
11405632   

EMBL

ABLF02041861    NEVH01006736    PNF36716.1    NEVH01019963    PNF22185.1    NEVH01005295    + More
PNF38784.1    KU543673    AMS38352.1    ABLF02034460    GFTR01008251    JAW08175.1    AY508487    AAS13459.1    X17551    CAA35587.1    AY047531    AAK77263.1    LBMM01012041    KMQ86458.1    GAKP01017773    JAC41179.1    GGMR01000676    MBY13295.1    GBGD01000389    JAC88500.1    GFTR01008269    JAW08157.1    GGMR01016905    MBY29524.1    GGMR01000226    MBY12845.1    ABLF02040877    ABLF02040900    GGMR01012443    MBY25062.1    GFTR01008260    JAW08166.1    GGMR01003407    MBY16026.1    GFTR01008271    JAW08155.1    GFTR01008246    JAW08180.1    GBBI01003747    JAC14965.1    GGMR01003864    MBY16483.1    GGMR01012305    MBY24924.1    GFXV01002840    MBW14645.1    GGMR01016296    MBY28915.1    GGMS01017365    MBY86568.1    GGMS01006359    MBY75562.1    GGMR01005022    MBY17641.1    GGMR01011511    MBY24130.1    AF237761    AAF81411.1    ABLF02025048    ABLF02063033   

Proteomes

UP000007819    UP000235965    UP000036403   

PRIDE

Q04135    Q961V7    Q9NBX4   

Pfam

PF00078   RVT_1        + More
PF07530   PRE_C2HC
PF14529   Exo_endo_phos_2

Interpro

IPR005135   Endo/exonuclease/phosphatase        + More
IPR006579   Pre_C2HC_dom       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR000477   RT_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

J9LYS0   A0A2J7R7D0   A0A2J7Q0S7   A0A2J7RD70   A0A142LX26   J9M0H4   + More
A0A224X6U5   Q6R811   Q04135   Q961V7   A0A0J7K7J8   A0A034VFD2   A0A2S2N814   A0A069DX78   A0A224X6R6   A0A2S2PJG2   A0A2S2N6Q7   J9LBQ6   A0A2S2P6S3   A0A224X6W2   A0A2S2NGV8   A0A224X6S1   A0A224XIB0   A0A023F0I3   A0A2S2NH02   A0A2S2P698   A0A2H8TKI9   A0A2S2PHL7   A0A2S2R9D4   A0A2S2QEE0   A0A2S2NKC3   A0A2S2P3X8   Q9NBX4   J9LMA3  

PDB

5I1R     E-value=0.0488833,     Score=90

KEGG

101741111    no KO assigned | (RefSeq) post-GPI attachment to proteins factor 2-like

GO

GO:0003964   GO:0006313   GO:0003676   GO:0008270   GO:0007275   GO:0016055   GO:0009166   GO:0005839   GO:0051603   GO:0046835   GO:0006281   GO:0006259  

Length:

1229

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.38676

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00001

outside

1  -  1229

 

 

Pi

297.581924

Theta

181.29883

Tajima's D

2.072502

CLR

0.796564

CSRT

0.894605269736513

Interpretation

Uncertain