Gene

KWMTBOMO16315

Pre Gene Modal

BGIBMGA013775

Annotation

PREDICTED:_multiple_C2_and_transmembrane_domain-containing_protein_1-like_[Bombyx_mori]

Location

Bomo_Chr28(+):5250849-5263580      View in EpiBrowser

Full name

Multiple C2 and transmembrane domain-containing protein      

Location in the cell

Cytoplasmic   Reliability : 2.193 Nuclear   Reliability : 1.722

CDS

ATGCAGTTGGAACAAGACGAAACACAAAGGCTTAGAGAGCAACATCTTAGGCAGTACGCCTTCTTCCAACTGAGGGTTCATTTAAAAAGAGGACAAAATCTGTTGGCAATGGACAAAAATGGAACAAGCGACCCGTACGTGAAATTCAAAGCCGGCGGAAGACTATTGCACAAATCAAGAATAGTTTACAGAGATCTGAATCCTGTTTGGGATGAATGTTTTACGGTGCCGGTTGAAGATCCCTTCCAGCCTGTGCAGATTAAGGTCTTCGATTACGATTGGGGCCTGCAAGACGATTTCATGGGCTCGTGCAATCTAGACCTGACAGCGTTAGAGCTCGGAAGGATGCAAGACCTGGTCCTTTGCTTGAGAGACCCGAACAAGCCGCACCAGGATATGGGAGAAATCGTTCTGAACGTTACTCTTTGGCCAAAATCACAGGAAGACAAGGATCAGGTAAGAGTTTGTATGTGTGCGCATGGTTAA

Protein

MQLEQDETQRLREQHLRQYAFFQLRVHLKRGQNLLAMDKNGTSDPYVKFKAGGRLLHKSRIVYRDLNPVWDECFTVPVEDPFQPVQIKVFDYDWGLQDDFMGSCNLDLTALELGRMQDLVLCLRDPNKPHQDMGEIVLNVTLWPKSQEDKDQVRVCMCAHG

Description

Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity (PubMed:28485711).

Cofactor

Ca(2+)

Keywords

Alternative splicing   Calcium   Complete proteome   Endoplasmic reticulum   Membrane   Reference proteome   Repeat   Transmembrane   Transmembrane helix  

Feature

chain  Multiple C2 and transmembrane domain-containing protein
splice variant  In isoform 2.

Uniprot

A0A0N0PA50   A0A212F330   A0A2A4K984   A0A2W1BKK6   A0A0L7KZP4   H9JW62   + More
A0A2H1VHN1   Q174I4   A0A1S4FEW1   A0A1L8DKH9   T1E932   A0A1A9XHA6   A0A0A1XHY1   W5JVS6   A0A1B0DNA3   A0A1Y1M4U5   A0A1Y1M080   A0A1I8MDU5   A0A0J7N7P9   B0XE00   B4JA15   A0A1Y1M5V4   A0A1S4FEV1   A0A182GQ57   D6WUE3   A0A139WFN8   A0A139WFX4   B0XKD0   A0A182Q4S6   B4GA38   A0A182FIA8   A0A1B0AMI4   A0A1A9URC3   A0A1B0G1V4   A0A1I8PKP5   A0A1A9WYX3   A0A0P6IW11   A0A088A9U7   A0A084VFA7   A0A2A3ENN7   A0A182NHJ8   A0A182J121   A0A182VKM5   A0A182KRV2   B4KPK1   A0A182RFQ2   B4LJ33   E2B859   Q5TX35   A0A182X6G0   A0A182I3R3   N6TJP3   A0A182WIT4   A0A0M3QVE9   A0A182UEL5   A0A1W4WMX6   E2AYX5   A0A1Q3G4Q9   A0A1Q3G4R3   A0A182JQQ1   U4UKD4   A0A182MA45   A0A158NNP2   A0A1Q3G4S1   A0A1Q3G4S2   A0A151X947   F4WQE3   A0A195B3G7   A0A195F6N0   E9IAS2   B4HP14   A0A310S7H1   T1I1Y3   B4QD29   A0A1B6EFX5   A0A1B6DM47   A0A0C9RHL5   Q291X9   A0A195DKS0   A0A0L7QX92   A0A1W4UMC6   B4MK12   A0A3B0JJV9   A0A3B0IZD0   A0A182P9V6   A0A154NZ39   A0A3B0IZ23   A0A182XZH8   V9IEV3   V9IFE7   K7IS27   A0A151I9P9   A0A0M9A7A8   A1ZBD6   A1ZBD6-2   A0A0J9RG79   B3MI22   B3NKB2   B4P491   A0A336MFH5  

Pubmed

26354079    22118469    28756777    26227816    19121390    17510324    + More
25830018    20920257    23761445    28004739    25315136    17994087    26483478    18362917    19820115    26999592    24438588    20966253    20798317    12364791    23537049    21347285    21719571    21282665    15632085    25244985    20075255    10731132    12537572    28485711    22936249    17550304   

EMBL

KQ459166    KPJ03576.1    AGBW02010634    OWR48140.1    NWSH01000040    PCG80353.1    + More
KZ150109    PZC73376.1    JTDY01004077    KOB68635.1    BABH01025335    BABH01025336    ODYU01002366    SOQ39774.1    CH477410    EAT41474.1    GFDF01007199    JAV06885.1    GAMD01001687    JAA99903.1    GBXI01009905    GBXI01009819    GBXI01003706    JAD04387.1    JAD04473.1    JAD10586.1    ADMH02000160    ETN67533.1    AJVK01007466    GEZM01043136    JAV79285.1    GEZM01043137    JAV79284.1    LBMM01008723    KMQ88670.1    DS232793    EDS45772.1    CH916367    EDW02602.1    GEZM01043135    JAV79286.1    JXUM01079729    JXUM01079730    JXUM01079731    JXUM01079732    KQ971352    EFA07297.2    KYB26752.1    KYB26751.1    DS233796    EDS31646.1    AXCN02000592    CH479181    EDW31790.1    JXJN01000456    CCAG010001058    CCAG010001059    GDUN01000054    JAN95865.1    ATLV01012371    KE524785    KFB36651.1    KZ288212    PBC32862.1    CH933808    EDW09111.2    CH940648    EDW61469.2    GL446283    EFN88121.1    AAAB01008807    EAL41731.2    APCN01000218    APGK01034847    APGK01034848    APGK01034849    APGK01034850    KB740923    ENN78073.1    CP012524    ALC42299.1    GL444028    EFN61345.1    GFDL01000258    JAV34787.1    GFDL01000254    JAV34791.1    KB632339    ERL92928.1    AXCM01001910    ADTU01021618    ADTU01021619    GFDL01000251    JAV34794.1    GFDL01000252    JAV34793.1    KQ982383    KYQ56897.1    GL888273    EGI63543.1    KQ976641    KYM78739.1    KQ981744    KYN36255.1    GL762047    EFZ22349.1    CH480816    EDW48516.1    KQ773232    OAD52398.1    ACPB03005944    CM000362    EDX07734.1    GEDC01000524    JAS36774.1    GEDC01010549    JAS26749.1    GBYB01000914    GBYB01006426    JAG70681.1    JAG76193.1    CM000071    EAL24983.3    KQ980765    KYN13437.1    KQ414705    KOC63159.1    CH963846    EDW72451.2    OUUW01000001    SPP73516.1    SPP73515.1    KQ434783    KZC04883.1    SPP73514.1    JR040572    AEY59192.1    JR040571    AEY59191.1    KQ978273    KYM95768.1    KQ435732    KOX77403.1    AE013599    CM002911    KMY94937.1    CH902619    EDV38032.2    CH954179    EDV55134.2    CM000158    EDW91577.2    UFQT01001061    SSX28680.1   

Proteomes

UP000053268    UP000007151    UP000218220    UP000037510    UP000005204    UP000008820    + More
UP000092443    UP000000673    UP000092462    UP000095301    UP000036403    UP000002320    UP000001070    UP000069940    UP000007266    UP000075886    UP000008744    UP000069272    UP000092460    UP000078200    UP000092444    UP000095300    UP000091820    UP000005203    UP000030765    UP000242457    UP000075884    UP000075880    UP000075903    UP000075882    UP000009192    UP000075900    UP000008792    UP000008237    UP000007062    UP000076407    UP000075840    UP000019118    UP000075920    UP000092553    UP000075902    UP000192223    UP000000311    UP000075881    UP000030742    UP000075883    UP000005205    UP000075809    UP000007755    UP000078540    UP000078541    UP000001292    UP000015103    UP000000304    UP000001819    UP000078492    UP000053825    UP000192221    UP000007798    UP000268350    UP000075885    UP000076502    UP000076408    UP000002358    UP000078542    UP000053105    UP000000803    UP000007801    UP000008711    UP000002282   

PRIDE

H9JW62    A1ZBD6   

Pfam

PF00168   C2        + More
PF08372   PRT_C
PF06398   Pex24p

Interpro

IPR035892   C2_domain_sf        + More
IPR000008   C2_dom       
IPR013583   PRibTrfase_C       
IPR010482   Peroxin       

Gene 3D

2.60.40.150    

ProteinModelPortal

A0A0N0PA50   A0A212F330   A0A2A4K984   A0A2W1BKK6   A0A0L7KZP4   H9JW62   + More
A0A2H1VHN1   Q174I4   A0A1S4FEW1   A0A1L8DKH9   T1E932   A0A1A9XHA6   A0A0A1XHY1   W5JVS6   A0A1B0DNA3   A0A1Y1M4U5   A0A1Y1M080   A0A1I8MDU5   A0A0J7N7P9   B0XE00   B4JA15   A0A1Y1M5V4   A0A1S4FEV1   A0A182GQ57   D6WUE3   A0A139WFN8   A0A139WFX4   B0XKD0   A0A182Q4S6   B4GA38   A0A182FIA8   A0A1B0AMI4   A0A1A9URC3   A0A1B0G1V4   A0A1I8PKP5   A0A1A9WYX3   A0A0P6IW11   A0A088A9U7   A0A084VFA7   A0A2A3ENN7   A0A182NHJ8   A0A182J121   A0A182VKM5   A0A182KRV2   B4KPK1   A0A182RFQ2   B4LJ33   E2B859   Q5TX35   A0A182X6G0   A0A182I3R3   N6TJP3   A0A182WIT4   A0A0M3QVE9   A0A182UEL5   A0A1W4WMX6   E2AYX5   A0A1Q3G4Q9   A0A1Q3G4R3   A0A182JQQ1   U4UKD4   A0A182MA45   A0A158NNP2   A0A1Q3G4S1   A0A1Q3G4S2   A0A151X947   F4WQE3   A0A195B3G7   A0A195F6N0   E9IAS2   B4HP14   A0A310S7H1   T1I1Y3   B4QD29   A0A1B6EFX5   A0A1B6DM47   A0A0C9RHL5   Q291X9   A0A195DKS0   A0A0L7QX92   A0A1W4UMC6   B4MK12   A0A3B0JJV9   A0A3B0IZD0   A0A182P9V6   A0A154NZ39   A0A3B0IZ23   A0A182XZH8   V9IEV3   V9IFE7   K7IS27   A0A151I9P9   A0A0M9A7A8   A1ZBD6   A1ZBD6-2   A0A0J9RG79   B3MI22   B3NKB2   B4P491   A0A336MFH5  

PDB

5A52     E-value=2.7278e-11,     Score=160

KEGG

105842993    no KO assigned | (RefSeq) multiple C2 and transmembrane domain-containing protein 1-like

GO

GO:0016021   GO:0016301   GO:0030672   GO:0005509   GO:0046928   GO:0048168   GO:0005789   GO:0005515   GO:0009116   GO:0004850   GO:0005737   GO:0009166   GO:0005839   GO:0051603   GO:0046835   GO:0006281   GO:0006259  

Subcellular location

Endoplasmic reticulum membrane  

Length:

161

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.29425

outside

1  -  161

 

 

Pi

186.268795

Theta

160.845756

Tajima's D

0.234081

CLR

0.840595

CSRT

0.437478126093695

Interpretation

Uncertain