Gene

KWMTBOMO16299

Pre Gene Modal

BGIBMGA014066

Annotation

PREDICTED:_anoctamin-8_[Bombyx_mori]

Location

Bomo_Chr28(-):4877641-4929030      View in EpiBrowser

Full name

Anoctamin      

Location in the cell

PlasmaMembrane   Reliability : 2.907

CDS

ATGGATGGGGAGGACGGAGGCACCGGAAACACCGATAAAGAAGAACATGAGAGCAGCACGAATTCTACACCTCAAGAACATAAATCTTTCGCTGAATTTGCGAAAGATAAACTCGACAGTGCTGGACGAGAGCTCCGCAGACGTTTACCCATGGCCGGTCAGCTTGGGGCTCACCTGATGCATCCGAGGAGATTACTTCTACACTCAACTCCCACTCAGCAAACCGATGTAGTGCTGATATTTCCCAAAGGTCTACCAGACAGTATGCTTTTATGGTTGCTGCAGAAGCTCAGAGGGAGTAGGCCGCGACTACGTGTCTGCGTCAGGCAGCACGCCTCCTCTCAATGCTCAGCCTTCTACATCACAGCCGACGATGATGTATTGTTGCAGACGGCTGAAGAAGTGCACCTTCCAAAACAATTGAAACCAGAATTTGGTGGGGGATACAAGGAATTCACTGTACGCGATATGCATTGTTTTCAAAAGGGCTCGTCAGCATCAGAACTCCTCAATACGCAGGAGCGTGGAGTCCTCGTGAAGCACGTGCTGGAGTCAGCTCGTGCGGAAGCAGGCGATGAGCATGCTTTAGAACCGGCGTTAACCCTAAGGCCTGGACAAAGTATTGTGCCTGCGTGTGTGAGTCGGGGCGTTGTAGCGAATATGTTTCCGTTGCACGAAAGAAATTCTCTGGAGAACCTGCGGAAGAAGTGGGTGAAGACTTTCTTCTCCCCACAGCCTTTAGATGAAATAAGTGAATATTTCGGCGTCAAAATCGCGATGTATTTCGCTTGGCTCGGCCACTACACGCGGTCGCTGACCGTGCCGGCCGTCGTCGGTTTTATATTCTGGATATGGCTGGGCACTGCGAATGAGCAGTGGAAGGACATAGCGTACATGCTGTTCTCATTGTTCAATGTATTGTGGGCGTGCATTTATTTGGAGACTTGGAAAAGGTACTCCAACGTGTTGGCTTATAGATGGGGGACCCTAGACCAGCGCGACGACTTGCTTCTCGAGCCCCGACCGCTATTCCAGGGTGAAATGAGCATAAGTCCGGTGACTGGCCGCCCGGAGCCCCAGTACGCCTCGTGGCGACGTCGGGTGTGGCGACACTGTATATCGATGCCCGCCACGCTGCTGTGTCTGTGTGTGGCCGCCGGAGCAACCTTTGCACTTTTGCGTGCGCAGGATTGGTGGGAAAATAATATAGTATATTTCACGTGGATACCCCGTGCACTGCTGGCTGTAATCATCGCCGTGGAAGAAGAAGTTTACGCGAGGATAGCCAGGTGGCTAAATGACAAAGAAAACTATCGCCTCGATACGAAATATGAGAACCATCTGATTGTGAAAATTGCATTGTTTCAATTCGTGAACTCGTTCATGAGTTTGTTCTACATTGCGTTTTATCTACAGGATATGGATAAATTGAAGGAGCAATTAGCAGTGTTGCTAATAACTAGACAGGTAATCGGTAATCTGAAAGAATCTGCTTTGCCTTACCTGATTGAGAATCTTCGACTCGCCAAAATATGCGTCGACGTGTTCGGTGCGATCAGTCCTAGTAAAGCGCCCACGTGCACACAATTAAACGAATTGTTTGACAAGAAGAATGAATCTGTAGGCGATGCACAGGACGGCGCCGTGCCCAACGGCAGTGCAGAGAGCGATGAAAGGAGGGACTCAGAGCCCCTCGTCGGGCAGAAGGTCATACATCAAGCAGAATTGGAATCGCAGTTGTTTAAGTACGACGGAACGTTCGCCGAGTACCTAGAGATGTTGACGCAGCTGGGCCACGTGGTGCTGTTCTCGTCCGCCTTCCCGCTGGCGGCGGCGTGCGCGCTGCTCAACAACGCGGCCGAGGTGCGCGCCGACGCCTTCAAGCTGTGCCACGTCGCGCAGAGACCCTTCGGCGAGAGGGTCAACAGCATCGGCAGCTGGCAGAACGCCATGGAAGCCATAGTGGCGGTGGCGGTACTGGTGAACTGCGCGCTGATAGGACTGTCGGGGCCCGTGCACAGACTGCTGCCGGACGCCACGCCCGCACAAACTATACTCATCATTGTGGGATTAGAGCACATAGTTTTAGTGATAGTATTAGCGCTACGAATCGCGATACCTGAGATCCCGGGTTGGCTCGCTACAGAAATGGCAAAAGTCGAGTTTCAACGTCGAGAAGCGATTAAAAACGCACATGCACCTTTGCTGTCTGAATGTACAAGTCAAGACGACATCCGGCTGTCGTCTCGCAACACGCCGCGCACAATGACGCCCACGACTCCGAAACAAGCCGAAAAAGCCGATAAAAAGAAGATAAGCATCGGCAAAATACCTGAGATACCACCTTTTAGTTAA

Protein

MDGEDGGTGNTDKEEHESSTNSTPQEHKSFAEFAKDKLDSAGRELRRRLPMAGQLGAHLMHPRRLLLHSTPTQQTDVVLIFPKGLPDSMLLWLLQKLRGSRPRLRVCVRQHASSQCSAFYITADDDVLLQTAEEVHLPKQLKPEFGGGYKEFTVRDMHCFQKGSSASELLNTQERGVLVKHVLESARAEAGDEHALEPALTLRPGQSIVPACVSRGVVANMFPLHERNSLENLRKKWVKTFFSPQPLDEISEYFGVKIAMYFAWLGHYTRSLTVPAVVGFIFWIWLGTANEQWKDIAYMLFSLFNVLWACIYLETWKRYSNVLAYRWGTLDQRDDLLLEPRPLFQGEMSISPVTGRPEPQYASWRRRVWRHCISMPATLLCLCVAAGATFALLRAQDWWENNIVYFTWIPRALLAVIIAVEEEVYARIARWLNDKENYRLDTKYENHLIVKIALFQFVNSFMSLFYIAFYLQDMDKLKEQLAVLLITRQVIGNLKESALPYLIENLRLAKICVDVFGAISPSKAPTCTQLNELFDKKNESVGDAQDGAVPNGSAESDERRDSEPLVGQKVIHQAELESQLFKYDGTFAEYLEMLTQLGHVVLFSSAFPLAAACALLNNAAEVRADAFKLCHVAQRPFGERVNSIGSWQNAMEAIVAVAVLVNCALIGLSGPVHRLLPDATPAQTILIIVGLEHIVLVIVLALRIAIPEIPGWLATEMAKVEFQRREAIKNAHAPLLSECTSQDDIRLSSRNTPRTMTPTTPKQAEKADKKKISIGKIPEIPPFS

Similarity

Belongs to the anoctamin family.
Belongs to the peptidase S8 family.

Feature

chain  Anoctamin

Uniprot

A0A3S2NIA2   A0A2W1BYM2   A0A0N0PCR8   A0A1B6BX11   K7IS28   F4WQE1   + More
A0A232ENE3   A0A0C9QA67   V9IDW2   A0A088A9V0   A0A0L7QX18   A0A195DKN4   A0A195F7U3   A0A154NYY1   D6WRQ5   A0A0N0BID2   A0A151I9L6   A0A151X994   T1HFC0   E2C170   A0A195B376   A0A026WLL0   E2AYX8   A0A1W4X945   A0A067QTS2   U4U0N3   N6TQ87   E0VQ68   T1IMB0   A0A0K8V6C9   A0A0K8UT94   A0A1I8MDJ5   A0A1W4W034   A0A1W4WAU9   A0A0M4E9C5   X2J9Y1   A0A0Q5W9S9   X2JE80   Q9V416   B3N5P1   A0A0J9R3I1   Q7KT76   A0A0J9R258   A0A0J9R2L6   A0A0J9TNM1   A0A0R1DN30   B4KLB3   B4NYE1   A0A0P8ZFW9   A0A0R3NX25   A0A0P8XFX5   B3MM99   A0A0Q9WR62   Q29P75   B4GK85   A0A0P8XWB2   B4MZE2   A0A0K8UTF9   A0A182XGY7   A0A3B0K7H6   A0A3B0K9J6   B4HXM4   A0A336LV50   A0A336M0G8   A0A182HR88   A0A1W4WC71   W8BXN5   A0A336LYX1   A0A1B0A844   B4Q5Z9   A0A087ZHV5   W5J5Y8   A0A182F552   M9PCX9   A0A182IUP3   A0A0J9R2N0   A0A1B0BFJ4   A0A0L0CJR6   Q17BF8   A0A0R3NQN6   A0A0J9TNM8   A0A182Y697   A0A2R5LCK2   A0A0Q9XBQ3   A0A0Q9X6X2   A0A1A9X8X8   J9KB30   A0A3B0KBE2   A0A1A9V174   A0A147BCM1   A0A1B0FL19   A0A182W8Q9   A0A182UDN0   A0A2P8Z3H1  

Pubmed

28756777    26354079    20075255    21719571    28648823    18362917    + More
19820115    20798317    24508170    24845553    23537049    20566863    25315136    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17994087    22936249    17550304    15632085    23185243    24495485    20920257    26109357    26109356    26108605    17510324    25244985    29652888    29403074   

EMBL

RSAL01000029    RVE51746.1    KZ149943    PZC76873.1    KQ460460    KPJ14638.1    + More
GEDC01031758    JAS05540.1    GL888273    EGI63541.1    NNAY01003184    OXU19847.1    GBYB01011308    JAG81075.1    JR039810    AEY58852.1    KQ414705    KOC63162.1    KQ980765    KYN13438.1    KQ981744    KYN36257.1    KQ434783    KZC04885.1    KQ971354    EFA05967.2    KQ435732    KOX77398.1    KQ978273    KYM95766.1    KQ982383    KYQ56899.1    ACPB03015452    ACPB03015453    GL451882    EFN78309.1    KQ976641    KYM78737.1    KK107154    EZA56930.1    GL444028    EFN61348.1    KK853284    KDR09005.1    KB631756    ERL85828.1    APGK01025214    APGK01025215    APGK01025216    KB740577    ENN80193.1    DS235389    EEB15524.1    JH431009    GDHF01017888    JAI34426.1    GDHF01022400    JAI29914.1    CP012523    ALC39715.1    AE014134    AHN54466.1    CH954177    KQS70220.1    AHN54465.1    AAF53439.1    EDV58000.2    CM002910    KMY90339.1    AAS64744.1    KMY90337.1    KMY90336.1    KMY90335.1    CM000157    KRJ98693.1    CH933807    EDW11774.2    EDW89777.2    CH902620    KPU73663.1    CH379058    KRT03488.1    KPU73665.1    EDV31859.1    CH963913    KRF98682.1    EAL34418.2    KRT03487.1    CH479184    EDW37051.1    KPU73664.1    EDW77481.2    GDHF01022536    JAI29778.1    OUUW01000052    SPP90034.1    SPP90033.1    CH480818    EDW51804.1    UFQT01000219    SSX21916.1    SSX21917.1    APCN01001657    APCN01001658    GAMC01008484    JAB98071.1    SSX21919.1    CM000361    EDX05102.1    GGFL01002370    MBW66548.1    ADMH02002089    ETN59391.1    AGB92994.1    KMY90338.1    JXJN01013491    JXJN01013492    JXJN01013493    JXJN01013494    JRES01000305    KNC32490.1    CH477322    EAT43586.1    KRT03489.1    KMY90340.1    GGLE01003070    MBY07196.1    KRG02906.1    KRG02905.1    ABLF02010405    SPP90032.1    GEGO01006893    JAR88511.1    CCAG010006621    CCAG010006622    CCAG010006623    PYGN01000213    PSN51037.1   

Proteomes

UP000283053    UP000053240    UP000002358    UP000007755    UP000215335    UP000005203    + More
UP000053825    UP000078492    UP000078541    UP000076502    UP000007266    UP000053105    UP000078542    UP000075809    UP000015103    UP000008237    UP000078540    UP000053097    UP000000311    UP000192223    UP000027135    UP000030742    UP000019118    UP000009046    UP000095301    UP000192221    UP000092553    UP000000803    UP000008711    UP000002282    UP000009192    UP000007801    UP000001819    UP000007798    UP000008744    UP000076407    UP000268350    UP000001292    UP000075840    UP000092445    UP000000304    UP000000673    UP000069272    UP000075880    UP000092460    UP000037069    UP000008820    UP000076408    UP000092443    UP000007819    UP000078200    UP000092444    UP000075920    UP000075902    UP000245037   

PRIDE

X2J9Y1    X2JE80    Q9V416    Q7KT76   

Pfam

PF04547   Anoctamin        + More
PF06679   DUF1180
PF08373   RAP
PF01483   P_proprotein
PF08368   FAST_2
PF16470   S8_pro-domain
PF08737   Rgp1
PF00082   Peptidase_S8

Interpro

IPR007632   Anoctamin        + More
IPR009565   DUF1180       
IPR015500   Peptidase_S8_subtilisin-rel       
IPR038466   S8_pro-domain_sf       
IPR013579   FAST_2       
IPR000209   Peptidase_S8/S53_dom       
IPR008979   Galactose-bd-like_sf       
IPR036852   Peptidase_S8/S53_dom_sf       
IPR006212   Furin_repeat       
IPR014848   Rgp1       
IPR023827   Peptidase_S8_Asp-AS       
IPR002884   P_dom       
IPR009030   Growth_fac_rcpt_cys_sf       
IPR022398   Peptidase_S8_His-AS       
IPR016017   GDNF/GAS1       
IPR032815   S8_pro-domain       
IPR034182   Kexin/furin       
IPR013584   RAP       
IPR023828   Peptidase_S8_Ser-AS       

SUPFAM

SSF57184   SSF57184        + More
SSF52743   SSF52743       
SSF49785   SSF49785       

Gene 3D

2.60.120.260     3.30.70.850     3.40.50.200    

CDD

cd00064  FU
cd04059  Peptidases_S8_Protein_converta

ProteinModelPortal

A0A3S2NIA2   A0A2W1BYM2   A0A0N0PCR8   A0A1B6BX11   K7IS28   F4WQE1   + More
A0A232ENE3   A0A0C9QA67   V9IDW2   A0A088A9V0   A0A0L7QX18   A0A195DKN4   A0A195F7U3   A0A154NYY1   D6WRQ5   A0A0N0BID2   A0A151I9L6   A0A151X994   T1HFC0   E2C170   A0A195B376   A0A026WLL0   E2AYX8   A0A1W4X945   A0A067QTS2   U4U0N3   N6TQ87   E0VQ68   T1IMB0   A0A0K8V6C9   A0A0K8UT94   A0A1I8MDJ5   A0A1W4W034   A0A1W4WAU9   A0A0M4E9C5   X2J9Y1   A0A0Q5W9S9   X2JE80   Q9V416   B3N5P1   A0A0J9R3I1   Q7KT76   A0A0J9R258   A0A0J9R2L6   A0A0J9TNM1   A0A0R1DN30   B4KLB3   B4NYE1   A0A0P8ZFW9   A0A0R3NX25   A0A0P8XFX5   B3MM99   A0A0Q9WR62   Q29P75   B4GK85   A0A0P8XWB2   B4MZE2   A0A0K8UTF9   A0A182XGY7   A0A3B0K7H6   A0A3B0K9J6   B4HXM4   A0A336LV50   A0A336M0G8   A0A182HR88   A0A1W4WC71   W8BXN5   A0A336LYX1   A0A1B0A844   B4Q5Z9   A0A087ZHV5   W5J5Y8   A0A182F552   M9PCX9   A0A182IUP3   A0A0J9R2N0   A0A1B0BFJ4   A0A0L0CJR6   Q17BF8   A0A0R3NQN6   A0A0J9TNM8   A0A182Y697   A0A2R5LCK2   A0A0Q9XBQ3   A0A0Q9X6X2   A0A1A9X8X8   J9KB30   A0A3B0KBE2   A0A1A9V174   A0A147BCM1   A0A1B0FL19   A0A182W8Q9   A0A182UDN0   A0A2P8Z3H1  

PDB

6R7Z     E-value=1.85533e-87,     Score=825

KEGG

101747096    K19502 anoctamin-8 | (RefSeq) anoctamin-8

GO

GO:0016021   GO:0004252   GO:0005227   GO:0006812   GO:0005229   GO:0006821   GO:0005886  

PANTHER

PTHR12308  

Subcellular location

Membrane  

Length:

784

Number of predicted TMHs:

8

Exp number of AAs in TMHs:

169.74223

Exp number, first 60 AAs:

0.0011

Total prob of N-in:

0.91881

inside

1  -  263

TMhelix

264  -  286

outside

287  -  295

TMhelix

296  -  313

inside

314  -  370

TMhelix

371  -  393

outside

394  -  402

TMhelix

403  -  420

inside

421  -  447

TMhelix

448  -  470

outside

471  -  596

TMhelix

597  -  619

inside

620  -  652

TMhelix

653  -  675

outside

676  -  684

TMhelix

685  -  707

inside

708  -  784

 

 

Pi

236.779725

Theta

178.732403

Tajima's D

1.195362

CLR

0.208126

CSRT

0.715514224288786

Interpretation

Uncertain