Gene

KWMTBOMO16250  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013902

Annotation

PREDICTED:_adenine_phosphoribosyltransferase_isoform_X3_[Bombyx_mori]

Location

Bomo_Chr28(-):2925045-2927142      View in EpiBrowser

Full name

Adenine phosphoribosyltransferase      

Location in the cell

Cytoplasmic   Reliability : 2.435

CDS

ATGAATAAAGACTACGAAAATAAAGTAGTCGTTCTAAAGAGTAAGATAAAAAGCTTTCCCGATTTTCCAAAAAAGGGAATCTTATTCTGGGACATATTTTCGGCAATATCAGATGGCAACATATGCAAACTATTGCAATCACTATTAGTTGATTGTATACGTACAAAATTTCCCGACGTAGAAGCTGTAGTTGGACTAGAATCTCGAGGATTCCTGTTCTCTTTCTCGCTTGCTTCAGAATTAGGAATCAGCTGTCTTTCAGTCAGGAAGAAGGGAAAGCTGCCAGGAGATGTAATATCTTATGAATATGATTTAGAATATGGTTCGGACACATTGGAAATCCAAAAAGATAAAATACGGCCAGGTTTAAAATGTCTGCTAGTTGATGATTTAATAGCAACTGGCGGTTCCATAACGGCCGCGACAAAATTACTGCAAACATGCGGTGCCGAAGTTCTTGGCTGTTTGGTCATCATTGAACTTAAAAGTTTGAAAGGAAGAGAGAACATTCCTGAAGGTATACCAGTGCATTCCTTGATTCAATATGAATAG

Protein

MNKDYENKVVVLKSKIKSFPDFPKKGILFWDIFSAISDGNICKLLQSLLVDCIRTKFPDVEAVVGLESRGFLFSFSLASELGISCLSVRKKGKLPGDVISYEYDLEYGSDTLEIQKDKIRPGLKCLLVDDLIATGGSITAATKLLQTCGAEVLGCLVIIELKSLKGRENIPEGIPVHSLIQYE

Description

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.

Catalytic Activity

AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine

Subunit

Homodimer.

Similarity

Belongs to the purine/pyrimidine phosphoribosyltransferase family.

Keywords

Complete proteome   Cytoplasm   Glycosyltransferase   Purine salvage   Reference proteome   Transferase  

Feature

chain  Adenine phosphoribosyltransferase

Uniprot

H9JWI8   A0A2W1BR32   A0A0N0P9T0   A0A0N1IQ42   A0A3S2TPQ1   A0A212F5X8   + More
A0A2H1W4Z6   A0A1B0AVU9   A0A1A9XRA0   D3TRH0   A0A1B0A291   A0A1B0FDG9   B4MXH1   A0A1A9VFE5   A0A1A9WGQ3   A0A0L0CKH2   Q1HQP5   B4KWW4   W8BVB6   A0A023EI33   A0A182GDY2   A0A0K8TSL2   A0A0M4ECZ8   A0A336LYK4   A0A034VRH8   A0A0K8WE68   A0A1Q3F7Q6   A0A0A1WX85   A0A1I8PVM9   A0A1L8DXR5   T1P9T4   A0A1B0CY73   B4PE88   B3NEX4   B4LH08   B4HW24   B0W403   B4IWQ2   B4QN03   A0A1W4W4M8   B4GS35   A0A182PMK4   X2J8L3   P12426   A0A182TII2   A0A182L305   Q7Q6Q8   A0A182HWL7   A0A2M4CLT0   A0A2M4CMW2   W5JSA6   A0A2M4C0G3   A0A182XMQ9   A0A182YD60   O44095   A0A084WDM3   A0A3B0JRX2   P54363   A0A182K8C4   A0A2M4C0H2   A0A182NIC5   A0A182MVT3   A0A2M4C0H3   A0A182WKV2   A0A2M3ZIG3   A0A182QN99   A0A2M4AN20   A0A2M3ZA44   A0A182T3T6   U5EJG9   A0A226F3J2   A0A0T6B7M4   B3M785   B5FX92   A0A0Q9XMW8   A0A1Y1MCW1   A0A2R7X0S6   E9IH41   A0A1J1J515   A0A026X030   A0A3S3PL76   A0A091HKD1   A0A1B0CP83   W5KUD4   A0A195C7F2   A0A158NTX8   D6WSW8   A0A182FE58   A0A2P8XH02   A0A0D2WKN8   A0A0B7AU19   F4WUB2   A0A3Q0SKE6   A0A3B4FJ72   A0A3P8NYD3   A0A3P9CR19   A0A0F8B451   I3K5Y7  

EC Number

2.4.2.7

Pubmed

19121390    28756777    26354079    22118469    20353571    17994087    + More
26108605    17204158    17510324    24495485    24945155    26483478    26369729    25348373    25830018    25315136    17550304    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    3125085    8492806    12537569    20966253    12364791    14747013    17210077    20920257    23761445    25244985    9720289    24438588    15632085    17018643    28004739    21282665    24508170    30249741    25329095    21347285    18362917    19820115    29403074    21719571    25186727    25835551   

EMBL

BABH01018578    KZ149970    PZC76075.1    KQ459166    KPJ03555.1    KQ459992    + More
KPJ18602.1    RSAL01000029    RVE51766.1    AGBW02010113    OWR49142.1    ODYU01006364    SOQ48151.1    JXJN01004398    EZ424022    ADD20298.1    CCAG010014128    CH963876    EDW76740.1    JRES01000281    KNC32727.1    DQ440399    CH477368    ABF18432.1    EAT42485.1    CH933809    EDW18585.1    GAMC01001281    GAMC01001280    JAC05276.1    JXUM01011310    GAPW01004851    KQ560328    JAC08747.1    KXJ83016.1    JXUM01010024    KQ560297    KXJ83185.1    GDAI01000241    JAI17362.1    CP012525    ALC43384.1    UFQT01000305    SSX23062.1    GAKP01013878    JAC45074.1    GDHF01003164    JAI49150.1    GFDL01011468    JAV23577.1    GBXI01011157    JAD03135.1    GFDF01002834    JAV11250.1    KA645477    AFP60106.1    AJWK01035517    CM000159    EDW92926.1    CH954178    EDV50247.1    CH940647    EDW69498.1    CH480817    EDW50139.1    DS231833    EDS32300.1    CH916366    EDV96278.1    CM000363    CM002912    EDX08885.1    KMY96983.1    CH479188    EDW40570.1    AE014296    AHN57933.1    AHN57934.1    M18432    L06280    AY119066    AAAB01008960    EAA10726.4    APCN01001503    GGFL01002061    MBW66239.1    GGFL01002060    MBW66238.1    ADMH02000499    ETN66188.1    GGFJ01009676    MBW58817.1    AF025800    AAB87885.1    ATLV01023045    KE525339    KFB48317.1    OUUW01000009    SPP84884.1    L06281    CH379069    GGFJ01009672    MBW58813.1    AXCM01005962    GGFJ01009675    MBW58816.1    GGFM01007548    MBW28299.1    AXCN02000880    GGFK01008862    MBW42183.1    GGFM01004557    MBW25308.1    GANO01002238    JAB57633.1    LNIX01000001    OXA63486.1    LJIG01009329    KRT83297.1    CH902618    EDV38746.1    DQ213177    ACH43653.1    KRG06270.1    GEZM01038245    JAV81696.1    KK856295    PTY25407.1    GL763174    EFZ20096.1    CVRI01000067    CRL06900.1    KK107054    QOIP01000004    EZA61607.1    RLU23916.1    NCKU01006308    NCKU01006051    NCKU01005112    RWS03639.1    RWS03883.1    RWS05000.1    KL217481    KFO95649.1    AJWK01021534    KQ978143    KYM96804.1    ADTU01026194    KQ971352    EFA06669.1    PYGN01002161    PSN31287.1    AVFK01000008    KJB95179.1    HACG01036606    CEK83471.1    GL888355    EGI62220.1    KQ041719    KKF23533.1    AERX01042073    AERX01042074   

Proteomes

UP000005204    UP000053268    UP000053240    UP000283053    UP000007151    UP000092460    + More
UP000092443    UP000092445    UP000092444    UP000007798    UP000078200    UP000091820    UP000037069    UP000008820    UP000009192    UP000069940    UP000249989    UP000092553    UP000095300    UP000095301    UP000092461    UP000002282    UP000008711    UP000008792    UP000001292    UP000002320    UP000001070    UP000000304    UP000192221    UP000008744    UP000075885    UP000000803    UP000075902    UP000075882    UP000007062    UP000075840    UP000000673    UP000076407    UP000076408    UP000030765    UP000268350    UP000001819    UP000075881    UP000075884    UP000075883    UP000075920    UP000075886    UP000075901    UP000198287    UP000007801    UP000183832    UP000053097    UP000279307    UP000285301    UP000054308    UP000018467    UP000078542    UP000005205    UP000007266    UP000069272    UP000245037    UP000032292    UP000007755    UP000261340    UP000261460    UP000265100    UP000265160    UP000005207   

PRIDE

H9JWI8    X2J8L3    P12426   

Pfam

PF00156   Pribosyltran        + More
PF10242   L_HMGIC_fpl

Interpro

IPR005764   Ade_phspho_trans        + More
IPR029057   PRTase-like       
IPR000836   PRibTrfase_dom       
IPR019372   LHFPL       

SUPFAM

SSF53271   SSF53271       

CDD

cd06223  PRTases_typeI

ProteinModelPortal

H9JWI8   A0A2W1BR32   A0A0N0P9T0   A0A0N1IQ42   A0A3S2TPQ1   A0A212F5X8   + More
A0A2H1W4Z6   A0A1B0AVU9   A0A1A9XRA0   D3TRH0   A0A1B0A291   A0A1B0FDG9   B4MXH1   A0A1A9VFE5   A0A1A9WGQ3   A0A0L0CKH2   Q1HQP5   B4KWW4   W8BVB6   A0A023EI33   A0A182GDY2   A0A0K8TSL2   A0A0M4ECZ8   A0A336LYK4   A0A034VRH8   A0A0K8WE68   A0A1Q3F7Q6   A0A0A1WX85   A0A1I8PVM9   A0A1L8DXR5   T1P9T4   A0A1B0CY73   B4PE88   B3NEX4   B4LH08   B4HW24   B0W403   B4IWQ2   B4QN03   A0A1W4W4M8   B4GS35   A0A182PMK4   X2J8L3   P12426   A0A182TII2   A0A182L305   Q7Q6Q8   A0A182HWL7   A0A2M4CLT0   A0A2M4CMW2   W5JSA6   A0A2M4C0G3   A0A182XMQ9   A0A182YD60   O44095   A0A084WDM3   A0A3B0JRX2   P54363   A0A182K8C4   A0A2M4C0H2   A0A182NIC5   A0A182MVT3   A0A2M4C0H3   A0A182WKV2   A0A2M3ZIG3   A0A182QN99   A0A2M4AN20   A0A2M3ZA44   A0A182T3T6   U5EJG9   A0A226F3J2   A0A0T6B7M4   B3M785   B5FX92   A0A0Q9XMW8   A0A1Y1MCW1   A0A2R7X0S6   E9IH41   A0A1J1J515   A0A026X030   A0A3S3PL76   A0A091HKD1   A0A1B0CP83   W5KUD4   A0A195C7F2   A0A158NTX8   D6WSW8   A0A182FE58   A0A2P8XH02   A0A0D2WKN8   A0A0B7AU19   F4WUB2   A0A3Q0SKE6   A0A3B4FJ72   A0A3P8NYD3   A0A3P9CR19   A0A0F8B451   I3K5Y7  

PDB

1ZN9     E-value=4.12108e-38,     Score=392

KEGG

101736026    K00759 adenine phosphoribosyltransferase [EC:2.4.2.7] | (RefSeq) adenine phosphoribosyltransferase

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0009116   GO:0003999   GO:0006168   GO:0005737   GO:0006166   GO:0044209   GO:0016208   GO:0002055   GO:0016021   GO:0016757   GO:0006261   GO:0001678   GO:0005536   GO:0046835   GO:0006281   GO:0006259  

PANTHER

PTHR12489  

Subcellular location

Cytoplasm  

Length:

183

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.27732

Exp number, first 60 AAs:

0.16697

Total prob of N-in:

0.37826

outside

1  -  183

 

 

Pi

260.616602

Theta

195.564601

Tajima's D

1.091712

CLR

0.032155

CSRT

0.687515624218789

Interpretation

Uncertain