Gene

KWMTBOMO16227

Annotation

hypothetical_protein_KGM_18772_[Danaus_plexippus]

Location

Bomo_Chr28(-):2441530-2441918      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 20      

Alternative Name

Mediator complex subunit 20

Location in the cell

Cytoplasmic   Reliability : 1.246 Extracellular   Reliability : 1.07 Mitochondrial   Reliability : 1.105

CDS

ATGTTTTTGGAGAAAACATTACACAAACTGCAATATGTAAACAAAGATATATGCGATGAATTCTACAATCGAGCTAAGCTTTCAGAAGGCTTGAAAGAACCGAAGCATTATCTTTGTGGTTTCGCTGTAAACAACAAGAAAGACTGCGTTTGGGAGAACGGGATGGTGCTGGCCTCGAATTCAAGCGGAAAATGGCATTTGGTAATTCCAGCATTACGATTCAATAGTTAA

Protein

MFLEKTLHKLQYVNKDICDEFYNRAKLSEGLKEPKHYLCGFAVNNKKDCVWENGMVLASNSSGKWHLVIPALRFNS

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subunit

Component of the Mediator complex.

Similarity

Belongs to the Mediator complex subunit 20 family.

Uniprot

H9JWJ8   A0A2W1BFQ8   A0A3S2NLM8   A0A2A4J7X2   A0A2H1V6I4   A0A212FFY3   + More
A0A2W1BAP2   A0A3S2PC33   A0A2A4JA18   A0A2A4IUV9   A0A2A4JDR7   A0A2A4IV93   H9JWQ6   H9JCW8   A0A0N0P9S4   A0A2W1BDT8   A0A2W1BMC9   A0A2W1BIT1   A0A2A4K582   A0A2W1BBU7   A0A212FIR3   A0A2A4K0S1   A0A2W1BFG4   A0A2W1B9V3  

Pubmed

19121390    28756777    22118469    26354079   

EMBL

BABH01018538    KZ150272    PZC71666.1    RSAL01000292    RVE42883.1    NWSH01002470    + More
PCG68227.1    ODYU01000748    SOQ36002.1    AGBW02008747    OWR52642.1    KZ150580    PZC70497.1    RSAL01000110    RVE47121.1    NWSH01002196    PCG68935.1    NWSH01007524    PCG62930.1    NWSH01001967    PCG69543.1    NWSH01005865    PCG63887.1    BABH01018465    BABH01018466    BABH01027664    KQ459166    KPJ03535.1    KZ150238    PZC71944.1    KZ150028    PZC74775.1    KZ150097    PZC73594.1    NWSH01000169    PCG78820.1    KZ150243    PZC71891.1    AGBW02008343    OWR53612.1    NWSH01000267    PCG77875.1    PZC71947.1    PZC71948.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000007151    UP000053268   

PRIDE

H9JWJ8    H9JWQ6    H9JCW8   

Pfam

PF00089   Trypsin        + More
PF08612   Med20

Interpro

IPR009003   Peptidase_S1_PA        + More
IPR001254   Trypsin_dom       
IPR013921   Mediator_Med20       

SUPFAM

SSF50494   SSF50494       

ProteinModelPortal

H9JWJ8   A0A2W1BFQ8   A0A3S2NLM8   A0A2A4J7X2   A0A2H1V6I4   A0A212FFY3   + More
A0A2W1BAP2   A0A3S2PC33   A0A2A4JA18   A0A2A4IUV9   A0A2A4JDR7   A0A2A4IV93   H9JWQ6   H9JCW8   A0A0N0P9S4   A0A2W1BDT8   A0A2W1BMC9   A0A2W1BIT1   A0A2A4K582   A0A2W1BBU7   A0A212FIR3   A0A2A4K0S1   A0A2W1BFG4   A0A2W1B9V3  

KEGG

101746599    no KO assigned | (RefSeq) uncharacterized LOC101746599

GO

GO:0004252   GO:0016592   GO:0006357   GO:0003712  

PANTHER

PTHR12465  

Subcellular location

Nucleus  

Length:

76

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00604

Exp number, first 60 AAs:

0.00274

Total prob of N-in:

0.14349

outside

1  -  76

 

 

Pi

210.658831

Theta

128.455456

Tajima's D

1.929386

CLR

0

CSRT

0.867956602169891

Interpretation

Uncertain