Gene

KWMTBOMO16211  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013916

Annotation

PREDICTED:_6-phosphogluconolactonase_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr28(-):1884395-1886383      View in EpiBrowser

Full name

6-phosphogluconolactonase      

Location in the cell

Cytoplasmic   Reliability : 2.977

CDS

ATGACGATCATCAAAGTTATTGATGAAGAAGAAATCATCAGAAAACTATCGACATACATTCAAAAGATTTCAAACGACGCGATCTTGAATAGAAATAAATTCGTAGTTGGACTTTCTGGCGGCTCTGTCGTCAAATATTTATGTGAAGGTTTACCACAAGTTGAAACAGACTGGTCTAAATGGACTCTAGCCTTCTGTGATGAAAGAGTAGTACCTGAAGACAGCAGCGATTCTACATTCGGAATATACAAGAAAGATTTAATCCCTAAGACTGAATTAAAGGAGAGCCAGTTTATAACAATCAAACAAGGAGCTACAGCTCAAGAAACAGCAAAGGATTACATTGAAAAGTTAAGAAAAGTCTTTGGTGGAGATGATTTCAAATTTGACTTACTTCTACTTGGCATGGGACCAGATGGACACACATGCTCCCTGTTCCCAGGTCACAAATTGCTTGAAGAAACAGAAGATAAGGTAGCAGCTATAACAGATTCCCCAAAACCTCCACCGGAGAGAATCACATTAACTTATCCAGTTATAAATGGAGCAAGGAACTGTATTTTTGCTATTTCTGGGGCAGGGAAGTCAGAAATGGCTAAACGTATTCTAAAAGACAAAGAAGATTTACCAGCTGGTCGAGTGAAGCCGACAGACGGCTCTCTATATTGGATCCTGGACGAAGAAGCAGCTGTACATTTGTAA

Protein

MTIIKVIDEEEIIRKLSTYIQKISNDAILNRNKFVVGLSGGSVVKYLCEGLPQVETDWSKWTLAFCDERVVPEDSSDSTFGIYKKDLIPKTELKESQFITIKQGATAQETAKDYIEKLRKVFGGDDFKFDLLLLGMGPDGHTCSLFPGHKLLEETEDKVAAITDSPKPPPERITLTYPVINGARNCIFAISGAGKSEMAKRILKDKEDLPAGRVKPTDGSLYWILDEEAAVHL

Description

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic Activity

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)

Similarity

Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

Uniprot

H9JWK2   A2TF14   A0A0N1INN4   A0A194Q017   A0A212FC63   S4P9E4   + More
A0A2H1WMK7   A0A0L7LDU1   A0A2A4JCA4   A0A1W4XRF1   A0A2W1BG55   A0A2P8XFX3   A0A0C9Q5I1   D6WWZ6   A0A1B6CM29   A0A336MWD1   A0A1L8E2G0   A0A1B6H374   A0A232FBU0   K7IW11   A0A336MJQ0   A0A1Y1NEX0   A0A1L8E1T4   A0A0P4W4X3   A0A1L8E1Z4   A0A1B6KH60   A0A0P5KH27   A0A0P5BVL0   A0A0P5YXZ1   A0A154NZ42   A0A0N8DM66   A0A1L8E1M6   A0A310SHD3   A0A0P6IGJ5   A0A146LI57   A0A0A9WAB3   A0A0P5U6P0   A0A1I8N1L4   W8BW14   U4UTG0   A0A0K8SQJ7   N6U308   A0A0N0BL12   A0A1I8QA94   A0A2R7VY42   E2A481   A0A0L7QXE0   A0A069DQY8   F4WMX9   A0A224XJM6   A0A0P5CSK3   A0A195FUK7   A0A151HYV3   A0A158NSK5   A0A1S3KGS3   A0A023F1S0   A0A1B6K9M7   A0A0V0G8Q8   T1HIG0   A0A087TTH8   A0A151WIL5   A0A0A1XPE9   A0A2A3ESK3   A0A1B0GKZ1   A0A0P5E676   A0A0L0BMF2   A0A0P5T1I7   A0A0N7Z8V6   A0A210Q6A3   A0A0P5RE35   A0A0K8UDB3   W4XGH6   A0A026W4R4   T1JA20   A0A088A588   A0A2C9K2K9   A0A034V1A5   V4B8D7   E9GDE3   A0A0P5TED1   A0A1I8MXD4   A0A0B7B4I1   A0A023GGW8   G3MPZ5   U5EWT6   A0A131XJM1   A0A2S2PLM6   A0A067RLS3   A0A2H8THQ6   A0A0J7KT26   J9K0I9   A0A293MPE1   H3AHH1   A0A1D1W620   A0A1J1HM86   A0A224YS02   A0A131YTI9   L7M3L3   A0A131Y354   A0A0P5CEK3  

EC Number

3.1.1.31

Pubmed

19121390    26354079    22118469    23622113    26227816    28756777    + More
29403074    18362917    19820115    28648823    20075255    28004739    26823975    25401762    25315136    24495485    23537049    20798317    26334808    21719571    21347285    25474469    25830018    26108605    27129103    28812685    24508170    15562597    25348373    23254933    21292972    22216098    28049606    24845553    9215903    27649274    28797301    26830274    25576852   

EMBL

BABH01018477    EF198104    ABM90638.1    KQ460955    KPJ10244.1    KQ459583    + More
KPI98633.1    AGBW02009220    OWR51320.1    GAIX01009100    JAA83460.1    ODYU01009334    SOQ53684.1    JTDY01001611    KOB73366.1    NWSH01002132    PCG69070.1    KZ150509    PZC70643.1    PYGN01002284    PSN30910.1    GBYB01009318    JAG79085.1    KQ971361    EFA08071.1    GEDC01022863    JAS14435.1    UFQT01002057    SSX32557.1    GFDF01001389    JAV12695.1    GECZ01000634    JAS69135.1    NNAY01000450    OXU28304.1    UFQT01001350    SSX30160.1    GEZM01007487    GEZM01007486    GEZM01007485    GEZM01007484    GEZM01007483    JAV95155.1    GFDF01001391    JAV12693.1    GDRN01101384    JAI58391.1    GFDF01001390    JAV12694.1    GEBQ01029194    JAT10783.1    GDIQ01191076    JAK60649.1    GDIP01183501    JAJ39901.1    GDIP01053576    JAM50139.1    KQ434783    KZC04842.1    GDIP01020119    JAM83596.1    GFDF01001451    JAV12633.1    KQ759893    OAD62087.1    GDIQ01011478    JAN83259.1    GDHC01011440    JAQ07189.1    GBHO01040161    GBHO01013253    JAG03443.1    JAG30351.1    GDIP01117261    JAL86453.1    GAMC01013161    GAMC01013158    GAMC01013155    JAB93394.1    KB632356    ERL93410.1    GBRD01010182    JAG55642.1    APGK01041544    KB740994    ENN75955.1    KQ435687    KOX81368.1    KK854152    PTY12249.1    GL436596    EFN71752.1    KQ414705    KOC63226.1    GBGD01002822    JAC86067.1    GL888223    EGI64449.1    GFTR01003739    JAW12687.1    GDIP01171703    JAJ51699.1    KQ981261    KYN44101.1    KQ976720    KYM76708.1    ADTU01025002    ADTU01025003    ADTU01025004    ADTU01025005    GBBI01003255    JAC15457.1    GEBQ01031852    JAT08125.1    GECL01001774    JAP04350.1    ACPB03010283    KK116673    KFM68417.1    KQ983089    KYQ47651.1    GBXI01001542    JAD12750.1    KZ288191    PBC34494.1    AJWK01033970    GDIP01146504    GDIQ01198925    JAJ76898.1    JAK52800.1    JRES01001654    KNC21113.1    GDIP01132363    JAL71351.1    GDKW01002283    JAI54312.1    NEDP02004840    OWF44258.1    GDIQ01121552    JAL30174.1    GDHF01027761    JAI24553.1    AAGJ04037077    AAGJ04037078    KK107419    EZA51070.1    JH431980    GAKP01022678    JAC36274.1    KB203357    ESO84989.1    GL732540    EFX82067.1    GDIP01127664    JAL76050.1    HACG01040330    HACG01040331    CEK87195.1    CEK87196.1    GBBM01002304    JAC33114.1    JO843946    AEO35563.1    GANO01002822    JAB57049.1    GEFH01002261    JAP66320.1    GGMR01017157    MBY29776.1    KK852601    KDR20495.1    GFXV01001858    MBW13663.1    LBMM01003488    KMQ93476.1    ABLF02031720    GFWV01022810    MAA47537.1    AFYH01136520    AFYH01136521    BDGG01000019    GAV08881.1    CVRI01000004    CRK87566.1    GFPF01005608    MAA16754.1    GEDV01006702    JAP81855.1    GACK01006113    JAA58921.1    GEFM01002858    JAP72938.1    GDIP01171704    JAJ51698.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000037510    UP000218220    + More
UP000192223    UP000245037    UP000007266    UP000215335    UP000002358    UP000076502    UP000095301    UP000030742    UP000019118    UP000053105    UP000095300    UP000000311    UP000053825    UP000007755    UP000078541    UP000078540    UP000005205    UP000085678    UP000015103    UP000054359    UP000075809    UP000242457    UP000092461    UP000037069    UP000242188    UP000007110    UP000053097    UP000005203    UP000076420    UP000030746    UP000000305    UP000027135    UP000036403    UP000007819    UP000008672    UP000186922    UP000183832   

PRIDE

H9JWK2    A2TF14   

Pfam

PF01182   Glucosamine_iso        + More
PF11095   Gemin7
PF00567   TUDOR

Interpro

IPR039104   PGLS        + More
IPR005900   6-phosphogluconolactonase_DevB       
IPR006148   Glc/Gal-6P_isomerase       
IPR037171   NagB/RpiA_transferase-like       
IPR020338   SMN_gemin7       
IPR035437   SNase_OB-fold_sf       
IPR002999   Tudor       

SUPFAM

SSF100950   SSF100950       

Gene 3D

2.40.50.90    

CDD

cd01400  6PGL

ProteinModelPortal

H9JWK2   A2TF14   A0A0N1INN4   A0A194Q017   A0A212FC63   S4P9E4   + More
A0A2H1WMK7   A0A0L7LDU1   A0A2A4JCA4   A0A1W4XRF1   A0A2W1BG55   A0A2P8XFX3   A0A0C9Q5I1   D6WWZ6   A0A1B6CM29   A0A336MWD1   A0A1L8E2G0   A0A1B6H374   A0A232FBU0   K7IW11   A0A336MJQ0   A0A1Y1NEX0   A0A1L8E1T4   A0A0P4W4X3   A0A1L8E1Z4   A0A1B6KH60   A0A0P5KH27   A0A0P5BVL0   A0A0P5YXZ1   A0A154NZ42   A0A0N8DM66   A0A1L8E1M6   A0A310SHD3   A0A0P6IGJ5   A0A146LI57   A0A0A9WAB3   A0A0P5U6P0   A0A1I8N1L4   W8BW14   U4UTG0   A0A0K8SQJ7   N6U308   A0A0N0BL12   A0A1I8QA94   A0A2R7VY42   E2A481   A0A0L7QXE0   A0A069DQY8   F4WMX9   A0A224XJM6   A0A0P5CSK3   A0A195FUK7   A0A151HYV3   A0A158NSK5   A0A1S3KGS3   A0A023F1S0   A0A1B6K9M7   A0A0V0G8Q8   T1HIG0   A0A087TTH8   A0A151WIL5   A0A0A1XPE9   A0A2A3ESK3   A0A1B0GKZ1   A0A0P5E676   A0A0L0BMF2   A0A0P5T1I7   A0A0N7Z8V6   A0A210Q6A3   A0A0P5RE35   A0A0K8UDB3   W4XGH6   A0A026W4R4   T1JA20   A0A088A588   A0A2C9K2K9   A0A034V1A5   V4B8D7   E9GDE3   A0A0P5TED1   A0A1I8MXD4   A0A0B7B4I1   A0A023GGW8   G3MPZ5   U5EWT6   A0A131XJM1   A0A2S2PLM6   A0A067RLS3   A0A2H8THQ6   A0A0J7KT26   J9K0I9   A0A293MPE1   H3AHH1   A0A1D1W620   A0A1J1HM86   A0A224YS02   A0A131YTI9   L7M3L3   A0A131Y354   A0A0P5CEK3  

PDB

3ICO     E-value=1.74691e-17,     Score=216

KEGG

100037442    K01057 6-phosphogluconolactonase [EC:3.1.1.31] | (RefSeq) 6pgl; 6-phosphogluconolactonase

PATHWAY

00030    Pentose phosphate pathway - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)

GO

GO:0006098   GO:0005975   GO:0017057   GO:0016021   GO:0009051   GO:0034719   GO:0048478   GO:0008233   GO:0001678   GO:0005536   GO:0046835   GO:0006281   GO:0006259  

PANTHER

PTHR11054  

Length:

233

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02043

Exp number, first 60 AAs:

0.00492

Total prob of N-in:

0.07543

outside

1  -  233

 

 

Pi

200.561732

Theta

207.322876

Tajima's D

-0.608052

CLR

0

CSRT

0.214089295535223

Interpretation

Uncertain